Oxurion NV — Major Shareholding Notification 2025

May 28, 2025

Oxurion Receives Transparency Notifications from Atlas Special Opportunities II LLC

Leuven, BELGIUM – May 28, 2025 – 06:00 PM CET - Oxurion NV (Euronext Brussels: OXUR), a biopharmaceutical company headquartered in Leuven, today announced that, pursuant to Belgian Transparency legislation¹ it has received transparency notifications as follows:

Oxurion received a transparency notification on May 27, 2025, from Atlas Special Opportunities II, LLC indicating that as of May 22, 2025, it held 921,914 shares of the then outstanding 6,156,035 shares, and therefore crossed under the threshold (15%) by virtue of the selling of voting securities.

Oxurion received a transparency notification on May 28, 2025, from Atlas Special Opportunities II, LLC indicating that as of May 27, 2025, it held 609,382 shares of the then outstanding 6,156,035 shares, and therefore crossed under the threshold (10%) by virtue of the selling of voting securities.

About Oxurion

Oxurion NV (Euronext Brussels: OXUR) is a biopharmaceutical group in transition, combining therapeutic innovation with technologies applied to clinical research. Through its rapidly expanding technology division, Oxurion is building integrated expertise around clinical data, with the ambition to accelerate, secure, and transform the processes involved in developing new treatments. Oxurion is based in Leuven, Belgium. More information is available at www.oxurion.com.

Important information about forward-looking statements

Certain statements in this press release may be considered "forward-looking". Such forward-looking statements are based on current expectations, and, accordingly, entail and are influenced by various risks and uncertainties. The Company therefore cannot provide any assurance that such forward-looking statements will materialize and does not assume any obligation to update or revise any forward-looking statement, whether as a result of new information, future events, or any other reason. Additional information concerning risks and uncertainties affecting the business and other factors that could cause actual results to differ materially from any forwardlooking statement is contained in the Company's Annual Report. This press release does not constitute an offer or invitation for the sale or purchase of securities or assets of Oxurion in any jurisdiction. No securities of Oxurion may be offered or sold within the United States without registration under the U.S. Securities Act of 1933, as amended, or in compliance with an exemption therefrom, and in accordance with any applicable U.S. state securities laws.

For further information please contact:

Oxurion NV Pascal Ghoson Chief Executive Officer Pascal.ghoson@oxurion.com

________

1. Article 14, first paragraph, of the Law of 2 May 2007 on disclosure of major holdings.

ANNEX 1

FSMA	FINANCIAL SERVICES AND MARKETS AUTHORITY	Transparency notification Form TR-1 BE PARTI
1) Status of the notification
	Final
2) Issuer
ldentification number 0881-620-924	Name OXURION
3) Reason for the notification
	Acquisition or disposal of voting securities or voting rights
4) Notification by
	A person that notifies alone
5) Persons subject to the notification requirement
	Name	Address (for legal entities)
	Atlas Special Opportunities II LLC	2500 Westchester Avenue, Suite 401, Purchase, NY 10577
	6) Persons that dispose of voting rights (only to be filled in if art. 7 of the Law applies)
	Name	Address (for legal entities)
	Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6	Part II
7) Date on which the threshold is crossed
		22/05/2025 (DD/MM/YYYY)
8) Threshold that is crossed (in %)
	15
		If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10
9) Denominator
	6,156,035
	Please enter the denominator before filling in the data
10) Notified details

A) Voting rights	Previous notification	After the transaction
	# of voting rights	# of voting rights		% of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
Atlas Special Opportunities II LLC	1,230,728	921,914		14.98%
TOTAL		921.914	o	14.98%	0.00%

B) Equivalent financial instruments	After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							+
TOTAL					0.00%

The totals will be updated once you have clicked on

TOTAL (A & B)		# of voting rights % of voting rights
	CALCULATE	921,914	14.98%

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

Atlas Special Opportunities II LLC is not a controlled entity.

12) In case of proxy voting for only one GM

Holder	will cease to hold / will hold again	voting rights as of	DUMMACH

13) Additional information

On 19 May 2025 (with setternet date on 21 May 2025), Mas-Special Operation NY, as a result of which its stareholding decreased of 1,30,173 shares = 1,50%, denominator = 6,156,035).
On 20 May 2025 (with setternet date on 22 May 2025), Mas Special Opportunities II LC sold 21 (rich its stares of o 1 wirith its stares to 921,914 stares (= 1.98%, denominator = 6,156,035).

	Done at New York
On		22/05/2025 (DD/MM/YYYY)
	Name & capacity Patrick Vance, Proxyholder

Signature Patnick Vanu

For security reasons, the unsigned form in xlsx format should be
transmitted to Irp.fin@fsma.be. You can do this manually
OR if you have MS Outlook at your disposal via the "

In addition, a signed copy in PDE format should also be
transmitted.

ANNEX 2

FSMA	FINANCIAL SERVICES AND MARKETS AUTHORITY		Form TR-1 BE PART I	Transparency notification
1) Status of the notification
	Final
2) Issuer
	Name OXURION
ldentification number 0881-620-924
3) Reason for the notification
	Acquisition or disposal of voting securities or voting rights
4) Notification by
	A person that notifies alone
5) Persons subject to the notification requirement
	Name			Address (for legal entities)
	Atlas Special Opportunities II LLC			2500 Westchester Avenue, Suite 401, Purchase, NY 10577
6) Persons that dispose of voting rights (only to be filled in if art. 7 of the Law applies)
	Name			Address (for legal entities)
B	Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6			Part II
7) Date on which the threshold is crossed
			27/05/2025 (DD/MM/YYYY)
8) Threshold that is crossed (in %)
		10
	If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10
9) Denominator
		6,156,035
	Please enter the denominator before filling in the data
10) Notified details
A) Voting rights	Previous notification			After the transaction
	# of voting rights			# of voting rights Not linked to the		% of voting rights Not linked to the
Holders of voting rights			Linked to securities	securities	Linked to securities	securities

B) Equivalent financial instruments	After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							+
	TOTAL			0	0.00%
	The totals will be undated once you have alieked on <CALCULATES

The totals will be updated once you have clicked on <CALC

TOTAL (A & B)			# of voting rights % of voting rights
	CALCULATE	609,382	9.90%

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

Atlas Special Opportunities II LLC is not a controlled entity.

12) In case of proxy voting for only one GM

Holder	will cease to hold / will hold again	voting rights as of

13) Additional information

On 21 May 2021 (with setterned an 22 May 2025) Altas Special Oppromies II L.C sod 90,22 stares in Oxirion is starendring ecreased of 3,488 spaces = 1,51%.
denominator = 6,156,035).
On 22 May 2025 (with setternet date on 20 May 2020), Atlass in Ourion NY, as a result it wirit its stareholing ecorased b 630,004 shares = 10.25%,
denominator = 6,156,035).
On 20 May 2025 (with settenent date on 21 May 2025), Altas Special Opportunities II L.C sold 21,522 shares in Oxicon its stareholing decreased o 609, 302 squares (=9.90%,
denominator = 6,156,035).

For security reasons, the unsigned form in xlsx format should be
transmitted to trp.fin@fsma.be. You can do this manually
OR if you have MS Outlook at your disposal via th

In addition, a signed copy in PDE format should also be
transmitted.