Oxurion NV — Major Shareholding Notification 2025

Aug 6, 2025

Oxurion Receives Transparency Notifications from Atlas Special Opportunities II LLC

Leuven, BELGIUM – August 6, 2025 – 06:00 PM CET - Oxurion NV (Euronext Brussels: OXUR), a biopharmaceutical company headquartered in Leuven, today announced that, pursuant to Belgian Transparency legislation¹ it has received transparency notifications as follows:

Oxurion received a transparency notification on August 6, 2025, from Atlas Special Opportunities II, LLC indicating that as of July 24, 2025, it held 2,353,539 shares of the then outstanding 25,821,963 shares, and therefore crossed under the threshold (10%) by virtue of the selling of voting securities.

Oxurion received a transparency notification on August 6, 2025, from Atlas Special Opportunities II, LLC indicating that as of July 25, 2025, it held 4,422,057 shares of the then outstanding 36,983,581 shares, and therefore crossed above the threshold (10%) by virtue of the selling of voting securities.

About Oxurion

Oxurion NV (Euronext Brussels: OXUR) is a biopharmaceutical group in transition, combining therapeutic innovation with technologies applied to clinical research. Through its rapidly expanding technology division, Oxurion is building integrated expertise around clinical data, with the ambition to accelerate, secure, and transform the processes involved in developing new treatments. The Group's headquarters are based in Leuven, Belgium. More information is available at www.oxurion.com.

Important information about forward-looking statements

Certain statements in this press release may be considered "forward-looking". Such forward-looking statements are based on current expectations, and, accordingly, entail and are influenced by various risks and uncertainties. The Company therefore cannot provide any assurance that such forward-looking statements will materialize and does not assume any obligation to update or revise any forward-looking statement, whether as a result of new information, future events, or any other reason. Additional information concerning risks and uncertainties affecting the business and other factors that could cause actual results to differ materially from any forwardlooking statement is contained in the Company's Annual Report. This press release does not constitute an offer or invitation for the sale or purchase of securities or assets of Oxurion in any jurisdiction. No securities of Oxurion may be offered or sold within the United States without registration under the U.S. Securities Act of 1933, as amended, or in compliance with an exemption therefrom, and in accordance with any applicable U.S. state securities laws.

Additional Disclaimer

________

The planned investment in digital assets (such as Bitcoin and Ethereum) exposes the company to specific risks related to volatility, regulatory uncertainty, and cybersecurity. These factors may significantly affect the expected performance of the investments.

For further information please contact:

Oxurion NV Pascal Ghoson Chief Executive Officer Pascal.ghoson@oxurion.com

^1. Article 14, first paragraph, of the Law of 2 May 2007 on disclosure of major holdings.

ANNEX 1

FSMA MARKETS AUTHORITY	FINANCIAL SERVICES AND	Transparency notification Form TR-1 BE PART I
1) Status of the notification
	Final
2) Issuer
ldentification number 0881-620-924	Name OXURION
3) Reason for the notification
	Acquisition or disposal of voting secunties or voting rights
4) Notification by
	A person that notifies alone
5) Persons subject to the notification requirement
	Name	Address (for legal entities)
	Atlas Special Opportunities II LLC	2500 Westchester Avenue, Suite 401, Purchase, NY 10577
6) Persons that dispose of votinq rights (only to be filled in if art. 7 of the Law applies)
	Name	Address (for legal entities)
B	Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6	Part II
7) Date on which the threshold is crossed
		24/07/2025 (DD/MM/YYYYY)
8) Threshold that is crossed (in %)
		10
		If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10
9) Denominator
	25,821,963
	Please enter the denominator before filling in the data
10) Notified details
A) Voting rights	Previous notification	After the transaction

A) Voting rights	Previous notification		After the transaction
	# of voting rights		# of voting rights		% of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
Atlas Special Opportunities II LLC	1,845,939	2,353,539		9.11%
	TOTAL	2,353,539	0	9.11%	0.00%

B) Equivalent financial instruments	After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							+
	TOTAL			0	0.00%
D	The totals will be updated once you have clicked on

TOTAL (A & B)			# of voting rights % of voting rights
	CALCULATE	2,353,539	9.11%

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

Atlas Special Opportunities II LLC is not a controlled entity.

12) In case of proxy votinq for only one GM

Holder	will cease to hold / will hold again	voting rights as of

13) Additional information

On 14 of the stimes and comment CC asses of the R.C. Marc Comments a recordina sected are recorder recorder recordere recordere recordere recomment of the management of the m

	Done at New York
On		01/08/2025 (DD/MM/YYYYY)
	Name & capacity Patrick Vance, Proxyholder

Signature Patrick Vance

For security reasons, the unsigned form in xlsx format should be transmitted to trp.fin@fsma.be. You can do this manually
OR if you have MS Outlook at your disposal via the "Save & Send" button

In addition, a signed copy in PDE format should also be
transmitted.

ANNEX 2

FSMA	FINANCIAL SERVICES AND MARKETS AUTHORITY		Form TR-1 BE PART I	Transparency notification
1) Status of the notification
	Final
2) Issuer
ldentification number 0881-620-924	Name OXURION
3) Reason for the notification
	Acquisition or disposal of voting securities or voting rights
4) Notification by
	A person that notifies alone
5) Persons subject to the notification requirement
	Name			Address (for legal entities)
	Atlas Special Opportunities II LLC			2500 Westchester Avenue, Suite 401, Purchase, NY 10577
6) Persons that dispose of votinq rights (only to be filled in if art. 7 of the Law applies)
	Name			Address (for legal entities)
B	Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6			Part II
7) Date on which the threshold is crossed
			25/07/2025 (DD/MM/YYYY)
8) Threshold that is crossed (in %)
		10
	If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10
9) Denominator
		36,983,581
	Please enter the denominator before filling in the data
10) Notified details
A) Voting rights	Previous notification			After the transaction
	# of voting rights			# of voting rights Not linked to the	% of voting rights Not linked to the

	# of voting rights	# of voting rights		% of voting rights
Holders of voting rights		Linked to securities	Not linked to the secunties	Linked to securities	Not linked to securities
Atlas Special Opportunities II LLC	2,353,539	4.422,057		11.96%
	TOTAL	4,422,057	0	11.96%	0.00%

Start with "groups" of holders. Add subtotals with 2, and then finish with the persons who are "alone"
For groups, start with the ultimate controlling natural person or le

B) Equivalent financial instruments	After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							+
TOTAL			0	0.00%
3	The totals will be updated once you have clicked on

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

total (a & b)

CALCULATE

12) In case of proxy voting for only one GM

13) Additional information

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Cl. 20.03.6% e etherent date of 2.0 J2025). Alas Special Clarici N. sa sestil rishin is themicing terrest by 1.133 haves ( 1.13% hare ( 1.13% hav

Done at New York
On	01/08/2025 (DD/MM/YYYYY)
Name & capacity Patrick Vance, Proxyholder	-Signed by: Patrick Vance Signature - BADC4789B05442E.

For security reasons, the unsigned form in xlsx format should
be transmitted to trp.fin@fsma.be. You can do this manually
OR if you have MS Outlook at your disposal via th Send" button.

In addition, a signed copy in PDE format should also be transmitted.

of voting rights % of voting rights

11 96%

4.422.057