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BIOTRON LIMITED Share Issue/Capital Change 2025

Dec 18, 2025

Share Issue/Capital Change

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Level 2, 66 Hunter Street Sydney NSW 2000 Tel: (61-2) 9300 3344 Fax: (61-2) 9221 6333 E-mail: [email protected] Website: www.biotron.com.au

19 December 2025

The Manager Companies ASX Limited 20 Bridge Street Sydney NSW 2000

(2 pages by email)

Dear Madam

I attach the Top 20 Option Holders and Distribution Schedule for the listed options issued on today’s Appendixes 2A.

This announcement has been approved by the Company’s Managing Director.

Yours faithfully

Marcelo Mora Company Secretary