BIOTRON LIMITED — Director's Dealing 2023

Nov 26, 2023

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Level 2, 66 Hunter Street Sydney NSW 2000 Tel: (61-2) 9300 3344 Fax: (61-2) 9221 6333 E-mail: pnightingale@biotron.com.au Website: www.biotron.com.au

27 November 2023

The Manager Companies ASX Limited 20 Bridge Street SYDNEY NSW 2000

(3 pages by email)

Dear Madam,

DIRECTORS’ INTERESTS

In accordance with Listing Rule 3.19A, I attach Appendix 3Y, Change of Director's Interest Notice, for Dr. Michelle Miller.

This announcement has been approved by the Managing Director, Michelle Miller.

Yours sincerely

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Peter J. Nightingale Company Secretary

pjn11955

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name of entity	BIOTRON LIMITED
ABN	60 086 399 144

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Michelle Miller
Date of last notice	29 November 2022.

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Direct and Indirect.
Nature of indirect interest(including registered holder)Note: Provide details of the circumstances giving riseto the relevant interest.	Michelle Miller + Peter Clarke <Miller Clarke Super FundA/C> in which Michelle Miller has a beneficial interest.
Date of change	26 November 2023
No. of securities held prior to change	1,987,500 fully paid ordinary shares and 165,625 listed optionsheld by Michelle Miller;1,800,000 fully paid ordinary shares and 150,000 listed optionsheld by Michelle Miller + Peter Clarke <Miller Clarke SuperFund A/C>;1,000,000 26 November 2023, 20 cents options
Class	Unlisted options expired.
Number acquired	Nil
Number disposed	1,000,000 26 November 2023 20 cent options (expired);
Value/ConsiderationNote: If consideration is non-cash, provide detailsand estimated valuation.	1,000,000 options expired unexercised $Nil
No. of securities held after change	1,987,500 fully paid ordinary shares and 165,625 listed optionsheld by Michelle Miller;1,800,000 fully paid ordinary shares and 150,000 listed optionsheld by Michelle Miller + Peter Clarke <Miller Clarke SuperFund A/C>;
Nature of changeExample: on-market trade, off-market trade, exerciseof options, issue of securities under dividendreinvestmentplan, participation in buy-back.	Unlisted options expired unexercised

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011

Appendix 3Y Change of Director’s Interest Notice

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	Nil.
Nature of interest	N/A.
Name of registered holder(if issued securities)	N/A.
Date of change	N/A.
No. and class of securities towhich interest related prior tochangeNote: Details are only required for a contract inrelation to which the interest has changed.	N/A.
Interest acquired	N/A.
Interest disposed	N/A.
Value/ConsiderationNote: If consideration is non-cash, provide details andan estimated valuation.	N/A.
Interest after change	N/A.

Part 3 –[+] Closed period

Were the interests in thesecurities or contracts detailedabove traded during a+closedperiod where prior writtenclearance was required?	No.
If so, was prior written clearanceprovided to allow the trade toproceed during this period?	N/A.
If prior written clearance wasprovided, on what date was thisprovided?	N/A.

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011