BIOTRON LIMITED — Director's Dealing 2019

Nov 6, 2019

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Level 2, 66 Hunter Street Sydney NSW 2000 Tel: (61-2) 9300 3344 Fax: (61-2) 9221 6333 E-mail: pnightingale@biotron.com.au Website: www.biotron.com.au

7 November 2019

The Manager Companies ASX Limited 20 Bridge Street SYDNEY NSW 2000

(3 pages by email)

Dear Madam,

DIRECTORS’ INTERESTS

In accordance with Listing Rule 3.19A, I attach an Appendix 3Y, Change of Director's Interest Notice, for Michael J. Hoy.

Yours sincerely

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Peter J. Nightingale Company Secretary

pjn10142

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name	of	entityBIOTRON LIMITED
ABN		60 086 399 144

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Michael J. HOY
Date of last notice	25 October 2018.

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

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----- Start of picture text ----- Direct or indirect interest Indirect.Nature of indirect interest Umbiram Pty Limited <Michael Hoy Superfund(including registered holder) A/C> in which Michael Hoy has an interest.Note: Provide details of the circumstances giving rise to therelevant interest.Date of change 7 November 2019.No. of securities held prior to change 7,789,828 fully paid ordinary shares and1,557,965 12 December 2019 5 cent listedoptions held by Umbiram Pty Limited <MichaelHoy Superfund A/C>.Class Fully paid ordinary shares.12 December 2019, 5 cent listed options.Number acquired 1,557,965 fully paid ordinary shares acquired on7 November 2019 by the exercise of 12December 2019 options.Number disposed 1,557,965 12 December 2019 options exercised.Value/Consideration Options exercised at $0.05 per option.Note: If consideration is non-cash, provide details and estimatedvaluation.No. of securities held after change 9,347,793 fully paid ordinary held by UmbiramPty Limited <Michael Hoy Superfund A/C>.Nature of change Exercise of options.Example: on-market trade, off-market trade, exercise of options,issue of securities under dividend reinvestment plan, participation inbuy-back.----- End of picture text -----

• See chapter 19 for defined terms.

Appendix 3Y Page 1

01/01/2011

Appendix 3Y Change of Director’s Interest Notice

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

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----- Start of picture text ----- Detail of contract Nil.Nature of interest N/A.Name of registered holder N/A.(if issued securities)Date of change N/A.No. and class of securities to which N/A.interest related prior to changeNote: Details are only required for a contract in relation to whichthe interest has changed.Interest acquired N/A.Interest disposed N/A.Value/Consideration N/A.Note: If consideration is non-cash, provide details and an estimatedvaluation.Interest after change N/A.----- End of picture text -----

Part 3 –[+] Closed period

art 3 –+Closed period
Were the interests in the securities orcontracts detailed above traded during a+closed period where prior writtenclearance was required?	No.
If so, was prior written clearanceprovided to allow the trade to proceedduring this period?	N/A.
If prior written clearance was provided,on what date was thisprovided?	N/A.

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011