BIOTRON LIMITED — Director's Dealing 2018

Nov 8, 2018

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Level 2, 66 Hunter Street Sydney NSW 2000 Tel: (61-2) 9300 3344 Fax: (61-2) 9221 6333 E-mail: pnightingale@biotron.com.au Website: www.biotron.com.au

9 November 2018

The Manager Companies ASX Limited 20 Bridge Street SYDNEY NSW 2000

(3 pages by email)

Dear Madam,

DIRECTORS’ INTERESTS

In accordance with Listing Rule 3.19A, I attach an Appendix 3Y, Change of Director's Interest Notice, for Dr Susan Pond.

Yours sincerely

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Peter J. Nightingale Company Secretary

pjn9689

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name	of	entityBIOTRON LIMITED
ABN		60 086 399 144

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Susan Pond
Date of last notice	14 June 2018

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

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----- Start of picture text ----- Direct or indirect interest Indirect.Nature of indirect interest BT Portfolio Services Limited <D&S Effeney(including registered holder) S/F A/C> in which Susan Pond has an interest.Note: Provide details of the circumstances giving rise to therelevant interest.Date of change 5 November to 9 November 2018.No. of securities held prior to change 545,246 fully paid ordinary shares, 87,239 30November 2018, 6 cent listed options and109,049 12 December 2019, 5 cent listed optionsheld by BT Portfolio Services Limited <D&SEffeney S/F A/C>.Class Fully paid ordinary shares.30 November 2018, 6 cent options.Number acquired 87,239 fully paid ordinary shares acquired on 9November 2018 by the exercise of 30 November2018 6 cent options.Number disposed 1.87,239 fully paid ordinary shares.2.87,239 30 November 2018 6 cent options.Value/Consideration 1.$12,431.56.Note: If consideration is non-cash, provide details and estimatedvaluation. 2.Options exercised at $0.06 per option.No. of securities held after change 545,246 fully paid ordinary shares and 109,04912 December 2019, 5 cent listed options held byBT Portfolio Services Limited <D&S EffeneyS/F A/C>.Nature of change 1. On market sale.Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in 2. Exercise of options.buy-back.----- End of picture text -----

Appendix 3Y Change of Director’s Interest Notice

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

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----- Start of picture text ----- Detail of contract Nil.Nature of interest N/A.Name of registered holder N/A.(if issued securities)Date of change N/A.No. and class of securities to which N/A.interest related prior to changeNote: Details are only required for a contract in relation to whichthe interest has changed.Interest acquired N/A.Interest disposed N/A.Value/Consideration N/A.Note: If consideration is non-cash, provide details and an estimatedvaluation.Interest after change N/A.----- End of picture text -----

Part 3 –[+] Closed period

Were the interests in the securities orcontracts detailed above traded during a+closed period where prior writtenclearance was required?	Yes.
If so, was prior written clearanceprovided to allow the trade to proceedduring this period?	Yes.
If prior written clearance was provided,on what date was thisprovided?	2 November 2018.

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011