Stoke Therapeutics, Inc.
Developing RNA-based medicines for genetic diseases by increasing protein from the healthy gene.
STOK | US
Overview
Corporate Details
- ISIN(s):
- US86150R1077
- LEI:
- Country:
- United States of America
- Address:
- 45 WIGGINS AVENUE, 1730 BEDFORD
- Sector:
- Manufacturing
- Industry:
- Manufacture of pharmaceuticals, medicinal chemical and botanical products
Description
Stoke Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing RNA-based medicines to treat severe genetic diseases. The company's proprietary research platform, TANGO (Targeted Augmentation of Nuclear Gene Output), aims to restore normal protein levels by increasing—or "stoking"—protein expression from the healthy copy of a mutated gene. This approach is primarily designed to address haploinsufficiencies, where a single functional gene is insufficient to prevent disease. Stoke's lead candidate, zorevunersen (STK-001), is in clinical development for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. The company's pipeline also includes programs for other genetic disorders, such as autosomal dominant optic atrophy (ADOA).
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Filings
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Market Data
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Financials & KPIs
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Insider Transactions
| Date | Insider Name | Position | Type | Shares | Value |
|---|---|---|---|---|---|
| No insider transactions recorded for this company. | |||||
Peer Companies
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