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Spyre Therapeutics, Inc. — Investor Relations & Filings

Ticker · SYRE ISIN · US00773J1034 LEI · 52990017AIJPRH3HQH40 US Manufacturing
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Filings indexed 740 across all filing types
Latest filing 2026-06-01 Regulatory Filings
Country US United States of America
Listing US SYRE

About Spyre Therapeutics, Inc.

https://spyre.com/

Spyre Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing next-generation therapeutics for patients with inflammatory bowel disease (IBD) and other immune-mediated conditions. The company's approach involves engineering novel antibodies with prolonged activity in the body, which allows for less frequent dosing. Its pipeline targets validated biological mechanisms and explores the use of these antibodies as both monotherapies and in rational combination therapies. Spyre aims to provide treatment options for various gastrointestinal and rheumatic diseases that offer the potential for enhanced efficacy and greater convenience.

Recent filings

Filing Released Lang Actions
8-K
Regulatory Filings Classification · 90% confidence The document is a U.S. SEC Form 8-K “Current Report” under the Securities Exchange Act of 1934, describing an amendment to a license agreement and listing an attached exhibit. It does not present full financial statements or detailed investor presentations, nor is it announcing dividends, management changes, or share issuances. It is a general regulatory filing under Form 8-K, making it best classified as a Regulatory Filing (RNS).
2026-06-01 English
8-K
Declaration of Voting Results & Voting Rights Announcements Classification · 88% confidence The document is a Form 8-K reporting Item 5.02 (departure and election of directors) and Item 5.07 (submission of matters to a vote of security holders) at the Annual Meeting, including detailed vote tallies for director elections, advisory votes, ratification of auditors, and plan approval. This matches the definition of a “Declaration of Voting Results & Voting Rights Announcements” (DVA), as it provides official voting results from a shareholder meeting.
2026-05-29 English
8-K - Spyre Therapeutics, Inc. (0001636282) (Filer)
Regulatory Filings Classification · 75% confidence The document is a SEC Form 8-K current report filed under the Securities Exchange Act, furnishing a press release of quarterly results as an exhibit. It does not contain the actual financial results itself but serves as a regulatory announcement. Form 8-K filings fall under General Regulatory Filings (RNS).
2026-05-05 English
10-Q - Spyre Therapeutics, Inc. (0001636282) (Filer)
Interim / Quarterly Report Q1 2026
2026-05-05 English
8-K - Spyre Therapeutics, Inc. (0001636282) (Filer)
Regulatory Filings
2026-04-16 English
424B5 - Spyre Therapeutics, Inc. (0001636282) (Filer)
Capital/Financing Update Classification · 100% confidence The document is a preliminary prospectus supplement filed pursuant to Rule 424(b)(5) under a shelf registration statement (Form S-3). It details an offering of $300 million of common stock, including underwriting details, risk factors, use of proceeds, and other offering-specific information. The document is clearly a capital raising filing related to a securities offering, not a financial report, earnings release, or management discussion. It is not an announcement of a report but the actual offering document. Therefore, it fits the category of Capital/Financing Update (CAP). The document length is substantial (15,000 characters), and it contains detailed offering terms, consistent with a prospectus supplement for a capital raise.
2026-04-13 English

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