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CIZZLE BIOTECHNOLOGY HOLDINGS PLC — Investor Relations & Filings

Ticker · CIZ ISIN · GB00BNG2VN02 LEI · 213800G3OS3SA2J1Y358 IL Professional, scientific and technical activities
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Filings indexed 305 across all filing types
Latest filing 2022-02-02 Major Shareholding Noti…
Country GB United Kingdom
Listing IL CIZ

About CIZZLE BIOTECHNOLOGY HOLDINGS PLC

https://cizzlebiotechnology.com/

Cizzle Biotechnology Holdings PLC is a cancer diagnostics developer focused on the early detection of lung cancer. The company is advancing a non-invasive, cost-effective blood test designed to identify lung cancer at its earliest stages, often before symptoms appear. The test utilizes a proprietary CIZ1B biomarker and an advanced immunoassay. Its primary goal is to improve patient outcomes by enabling swift, curative medical intervention. The technology aims to streamline the diagnostic pathway, reduce reliance on CT scans which can have high false-positive rates, and eliminate unnecessary invasive follow-up procedures. The company, a spin-out from the University of York, is conducting clinical trials to support global regulatory approval and adoption of its technology.

Recent filings

Filing Released Lang Actions
Holding(s) in Company
Major Shareholding Notification Classification · 1% confidence The document is explicitly titled 'TR-1: Standard form for notification of major holdings' and contains RNS Number information, indicating it is a regulatory filing related to share ownership changes. Specifically, it details an acquisition or disposal of voting rights by 'Rose Noble Limited' and references the FCA (Financial Conduct Authority). This type of filing, which reports changes in significant share ownership thresholds, corresponds directly to the Major Shareholding Notification category (MRQ). Although it is distributed via RNS, the specific content dictates the MRQ classification over the general RNS fallback.
2022-02-02 English
Holding(s) in Company
Major Shareholding Notification Classification · 1% confidence The document is explicitly titled 'TR-1: Standard form for notification of major holdings' and contains fields typical of a major shareholder disclosure, such as 'Identity of the issuer', 'Reason for the notification', 'Details of person subject to the notification obligation', and 'Total positions of person(s) subject to the notification obligation'. This form is used to report changes in significant share ownership, crossing notification thresholds. This directly corresponds to the definition of Major Shareholding Notification (MRQ). Although it is distributed via RNS, the content is specific to a major holding change, making MRQ the most accurate classification over the general RNS fallback.
2022-02-02 English
Holding(s) in Company
Major Shareholding Notification Classification · 1% confidence The document is explicitly labeled with 'RNS Number' and contains a standardized notification format titled 'TR-1: Standard form for notification of major holdings'. This form details changes in share ownership (acquisition or disposal of financial instruments) by a shareholder (Spreadex LTD) in the issuer (Cizzle Biotechnology Holdings plc). This type of mandatory disclosure regarding significant changes in shareholding thresholds is classified as a Major Shareholding Notification. Although it is distributed via RNS, the specific content dictates the 'MRQ' classification over the general 'RNS' fallback.
2022-01-19 English
Second Price Monitoring Extn
Regulatory Filings Classification · 1% confidence The document text explicitly starts with "RNS Number : 1880V" and contains information about a "Second Price Monitoring Extension" related to trading activity on the London Stock Exchange. The text concludes by stating, "This information is provided by RNS, the news service of the London Stock Exchange." This clearly identifies the document as a general regulatory announcement disseminated via the RNS system, which corresponds to the 'Regulatory Filings' category.
2021-12-09 English
Price Monitoring Extension
Regulatory Filings Classification · 1% confidence The document begins with 'RNS Number' and is distributed via 'RNS, the news service of the London Stock Exchange.' It announces a 'Price Monitoring Extension' for a security, which is a specific operational update related to trading mechanisms. This type of short, immediate regulatory announcement that doesn't fit into specific financial reporting categories (like 10-K, ER, or DIV) is best classified under the general regulatory announcement category.
2021-12-09 English
Holding(s) in Company
Major Shareholding Notification Classification · 1% confidence The document is explicitly labeled with "RNS Number : 8905U" and contains standard boilerplate language referencing RNS, the news service of the London Stock Exchange, and the Financial Conduct Authority (FCA). The content itself is a "TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES," detailing changes in voting rights and share ownership thresholds (crossing 9%). This type of mandatory disclosure regarding insider or major shareholder transactions/holdings is a specific regulatory filing. While it relates to director/insider activity (DIRS) or major shareholding changes (MRQ), the most accurate classification for a standard, structured regulatory notification filed via RNS that doesn't fit a more specific category like 10-K or ER, and is not a proxy statement (DEF 14A) or a general announcement of a report (RPA), is often captured under the general regulatory filing category, or the most specific fit. Since it details a change in major shareholding (crossing the 9% threshold), MRQ (Major Shareholding Notification) is highly relevant. However, TR-1 forms are often categorized broadly. Given the options, 'DIRS' covers director dealings, and 'MRQ' covers major shareholding changes. Since this is a notification of a major interest crossing a threshold (9%), MRQ is the most precise fit among the specific options provided for ownership changes. If MRQ were not available, RNS would be the fallback. Since MRQ is available, I select MRQ.
2021-12-07 English

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