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CIZZLE BIOTECHNOLOGY HOLDINGS PLC — Investor Relations & Filings

Ticker · CIZ ISIN · GB00BNG2VN02 LEI · 213800G3OS3SA2J1Y358 IL Professional, scientific and technical activities
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Filings indexed 305 across all filing types
Latest filing 2023-02-22 Major Shareholding Noti…
Country GB United Kingdom
Listing IL CIZ

About CIZZLE BIOTECHNOLOGY HOLDINGS PLC

https://cizzlebiotechnology.com/

Cizzle Biotechnology Holdings PLC is a cancer diagnostics developer focused on the early detection of lung cancer. The company is advancing a non-invasive, cost-effective blood test designed to identify lung cancer at its earliest stages, often before symptoms appear. The test utilizes a proprietary CIZ1B biomarker and an advanced immunoassay. Its primary goal is to improve patient outcomes by enabling swift, curative medical intervention. The technology aims to streamline the diagnostic pathway, reduce reliance on CT scans which can have high false-positive rates, and eliminate unnecessary invasive follow-up procedures. The company, a spin-out from the University of York, is conducting clinical trials to support global regulatory approval and adoption of its technology.

Recent filings

Filing Released Lang Actions
Holding(s) in Company
Major Shareholding Notification Classification · 1% confidence The document is identified by the RNS Number (6945Q) and the header 'TR-1: Standard form for notification of major holdings'. This form is used to report changes in significant share ownership, specifically detailing the acquisition or disposal of voting rights that cross a notification threshold. Section 7 shows the resulting situation (9.03%) and the previous notification (8.02%). This directly corresponds to the definition of 'Major Shareholding Notification' (Code: MRQ). Although it is an RNS filing, MRQ is the more specific category.
2023-02-22 English
Holding(s) in Company
Major Shareholding Notification Classification · 1% confidence The document is explicitly titled 'TR-1: Standard form for notification of major holdings' and contains fields related to the 'Identity of the issuer', 'Reason for the notification' (specifically 'An acquisition or disposal of voting rights'), and 'Total positions of person(s) subject to the notification obligation' detailing percentage changes in voting rights (e.g., 8.02% vs 7.52%). This structure is characteristic of regulatory filings concerning changes in significant share ownership. The presence of 'RNS Number' and reference to the 'FCA' (Financial Conduct Authority) confirms it is a regulatory announcement. The category that specifically covers 'Notification of changes in significant share ownership levels (crossing thresholds)' is Major Shareholding Notification (MRQ).
2023-02-06 English
Total Voting Rights
Declaration of Voting Results & Voting Rights Announcements Classification · 1% confidence The document is identified by the 'RNS Number' header and explicitly states it is providing information via 'RNS, the news service of the London Stock Exchange.' The content details the 'Total Voting Rights' as of a specific date (31 January 2023) and cites compliance with the FCA's Disclosure Guidance and Transparency Rules. This type of mandatory, periodic disclosure regarding share capital structure and voting rights is a standard regulatory announcement. Since it is a general regulatory announcement that doesn't fit a more specific category like Director's Dealing (DIRS) or Share Issue (SHA), the most appropriate classification is the general Regulatory Filings category (RNS). The document length (3218 chars) is short, but the content is the primary disclosure itself, not an announcement *about* a report, thus RPA is less suitable than RNS for this specific regulatory update.
2023-01-31 English
Holding(s) in Company
Major Shareholding Notification Classification · 1% confidence The document is explicitly titled 'TR-1: Standard form for notification of major holdings' and is filed via 'RNS Number : 7205N' by 'Cizzle Biotechnology Holdings PLC' on '24 January 2023'. This form is used to report changes in significant share ownership, crossing notification thresholds. This directly corresponds to the definition of Major Shareholding Notification (MRQ). Although it is distributed via RNS, the content is specific to a major holding change, making MRQ the most precise classification over the general RNS fallback.
2023-01-24 English
Update re. timing of Admission
Share Issue/Capital Change Classification · 1% confidence The document is very short (2978 characters) and announces an update regarding the timing of a share admission ('Update re. timing of Admission'). It references a previous announcement and provides a new expected effective date for the Admission. The text is clearly a brief regulatory notification, indicated by the 'RNS Number' header and the footer mentioning RNS, the news service of the London Stock Exchange, which acts as a Primary Information Provider. Since this is a short announcement about a corporate event (share listing/admission) that doesn't fit perfectly into the specific categories like DIV, CAP, or SHA (which usually deal with issuance/buybacks), and it is an official regulatory update, the most appropriate classification is the general regulatory announcement fallback category, RNS. It is not a full report, presentation, or transcript.
2022-12-20 English
Put Option re AZD1656 & £115,586 Subscription
M&A Activity Classification · 1% confidence The document is clearly identified as originating from 'RNS Number : 0752K' and contains the standard header 'This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom.' RNS filings cover a wide range of regulatory announcements that do not fit into more specific categories. The content details a corporate transaction (a put option agreement, a subscription for new shares, and related financing/merger news) which is a material event requiring immediate disclosure. Since this is a general regulatory announcement distributed via RNS and doesn't fit perfectly into categories like CAP (Capital/Financing Update, though it contains financing elements), DIV, or DIRS, the most appropriate general classification for a standard, material regulatory disclosure distributed via RNS is 'Regulatory Filings' (RNS). The document length (9305 chars) is substantial, indicating it is the full announcement, not just a brief notice of publication.
2022-12-19 English

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