ACTUATE THERAPEUTICS, INC. — Investor Relations & Filings

Actuate Therapeutics, Inc. is a clinical-stage biopharmaceutical company dedicated to developing therapies for cancers with high unmet medical needs. The company's lead drug candidate is elraglusib, a novel, first-in-class small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). Elraglusib is being developed for difficult-to-treat cancers, including metastatic pancreatic cancer. Its mechanism of action targets multiple molecular pathways involved in promoting tumor growth and resistance to conventional drugs. Additionally, it functions as a mediator of anti-tumor immunity by inhibiting immune checkpoints and regulating immune cell function. The company's goal is to develop therapies that can slow, stop, or shrink tumors with minimal adverse effects, thereby improving patient outcomes.