UCB — Major Shareholding Notification 2022

Mar 18, 2022

Transparency notification FMR LLC

Brussels (Belgium), 18 March 2022 – 20:05 (CET) – Regulated information

1. Summary of the notification

Pursuant to Article 14 of the law of 2 May 2007 on the disclosure of large shareholdings, UCB SA/NV announces that it has received a transparency notification from FMR LLC. (having its registered office at 245 Summer Street, Boston, Massachusetts, 02210, U.S.A.), on 16 March 2022.

FMR LLC., has notified that, following an acquisition of UCB shares with voting rights by its affiliates, its shareholding in UCB SA has increased and it has crossed the 5% threshold, on 14 March 2022.

On 14 March 2022, FMR LLC. (taking into account the holding of its affiliates) owned 9 770 956 UCB shares with voting rights, representing 5.02% of the total number of shares issued by the company (194 505 658), versus 4.98% (9 690 661 UCB shares) in the previous notification dated 31 January 2022.

2. Content of the notification

• Reason for the notification: Acquisition or disposal of voting securities or voting rights.
• Notification by: A parent undertaking or a controlling person.
• Persons subject to the notification requirement:

Name	Address (for legal entities)
FMR LLC	245 Summer Street, Boston, Massachusetts, 02210

• Date on which the threshold is crossed: 14 March 2022.
• Threshold crossed (in %): 5%.
• Denominator: 194 505 658.
• Notified details:

A) Voting rights Previous notification		After the transaction
# of voting rights						% of voting rights
							Not linked to the securities
0			0			0,00%
892.393		890.799			0,46%
Fidelity Institutional Asset Management 357.515 Trust Company		365.159				0,19%
Fidelity Management & Research 6.677.846		6.748.641			3,47%
Fidelity Management Trust Company 577.368		560.449			0,29%
FMR Investment Management (UK) 1.050.992 Limited		1.049.926				0,54%
134.547		155.622				0,08%
9.690.661		9.770.596				5,02%
TOTAL					0	5,02%	0,00%
After the transaction
Type of financial instrument		date			exercised		Settlement
TOTAL					0	0,00%
TOTAL (A & B)
				Linked to securities 9.770.596	Expiration date Exercise period or	# of voting rights Not linked to the securities	Linked to securities # of voting rights that may be acquired if the % of voting rights instrument is # of voting rights % of voting rights

• Chain of controlled undertakings through which the holding is effectively held:

CALCULATE 9.770.596 5,02%

Fidelity Institutional Asset Management Trust Company and FIAM LLC are controlled by FIAM Holdings LLC, FIAM Holdings LLC is controlled by FMR LLC Fidelity Management Trust Company is controlled by FMR LLC Fidelity Management & Research Company LLC is controlled by FMR LLC FMR Investment Management (UK) Limited is controlled by Fidelity Management & Research Company LLC Strategic Advisers LLC is controlled by Fidelity Advisory Holdings LLC Fidelity Advisory Holdings LLC is controlled by FMR LLC FMR LLC is not a controlled entity.

3. Further information

This press release and the detailed transparency notification are available on UCB SA/NV's website via the following link.

An updated overview of the UCB SA/NV large shareholdings will be available on UCB SA/NV's website via the following link.

For further information, contact UCB:

Investor Relations Antje Witte T +32 2 559 94 14 antje.witte@ucb.com

Corporate Communications Laurent Schots T+32 2 559 92 64 laurent.schots@ucb.com

About UCB

UCB, Brussels, Belgium (www.ucb.com) is a global biopharmaceutical company focused on the discovery and development of innovative medicines and solutions to transform the lives of people living with severe diseases of the immune system or of the central nervous system. With approximately 8 600 people in nearly 40 countries, the company generated revenue of € 5.8 billion in 2021. UCB is listed on Euronext Brussels (symbol: UCB). Follow us on Twitter: @UCB_news