TALPHERA, INC. — Director's Dealing 2025

Oct 16, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: TALPHERA, INC. (TLPH)
CIK: 0001427925
Period of Report: 2025-10-15

Reporting Person: Todisco Joseph (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-10-15	Common Stock	A	6397	—	Acquired	6397	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-10-15	Director Stock Option (right to buy)	$1.11	A	38381	Acquired	2035-10-14	Common Stock (38381)	Direct

Footnotes

F1: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F2: The restricted stock units shall vest in three equal consecutive annual installments on October 14, 2026, October 14, 2027, and October 14, 2028.

F3: The shares subject to the option shall vest in three equal consecutive annual installments on October 14, 2026, October 14, 2027, and October 14, 2028, subject to the Reporting Person's continuous service to the Company.