TALPHERA, INC. — Director's Dealing 2026

Feb 21, 2026

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: TALPHERA, INC. (TLPH)
CIK: 0001427925
Period of Report: 2026-02-10

Reporting Person: Angotti Vincent J. (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2026-02-10	Common Stock	F	3179	$0.8361	Disposed	481590	Direct
2026-02-12	Common Stock	P	105364	$0.8123	Acquired	586954	Direct
2026-02-14	Common Stock	F	9559	$0.7934	Disposed	577395	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2026-02-12	Stock Option (Right to Buy)	$0.8123	A	594000	Acquired	2036-02-11	Common Stock (594000)	Direct

Footnotes

F1: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of RSUs.

F2: Balance includes non-reportable acquisition of 10,000 shares of Common Stock through the Company's Employee Stock Purchase Plan.

F3: The restricted stock units shall vest in three equal consecutive annual installments on February 12, 2027, February 12, 2028 and February 12, 2029.

F4: On February 12, 2026, the reporting person was granted an option to purchase 594,000 shares of common stock. One fourth (1/4th) of the option shares shall vest on the one year anniversary of the grant date, and the remaining balance of the option shares shall vest in 36 equal consecutive monthly installments thereafter until fully vested so long as the reporting person remains in continuous service through such applicable vesting periods.