Sirnaomics Ltd. — Board/Management Information 2024

Dec 5, 2024

Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this announcement, make no representation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this announcement.

Sirnaomics Ltd.

(Incorporated in the Cayman Islands with limited liability)

(Stock Code: 2257)

RESIGNATION OF NON-EXECUTIVE DIRECTOR

The board (the "Board") of directors (the "Director(s)") of Sirnaomics Ltd. (the "Company") hereby announces that the Board has received a letter of resignation from Mr. Mincong Huang ("Mr. Huang") to resign as a non-executive Director and a member of the audit committee of the Board (the "Audit Committee") with effect from January 1, 2025, as Mr. Huang wishes to devote more time to his other commitments.

Mr. Huang has confirmed that he had no disagreement with the Board and there were no other matters relating to his resignation that need to be brought to the attention of the shareholders of the Company.

The Board would like to express its sincere gratitude to Mr. Huang for his valuable contribution to the Company during his tenure in office.

For continuous compliance with the Rules Governing the Listing of Securities on The Stock Exchange of Hong Kong Limited (the "Listing Rules"), the Company will make its best endeavor to identify a suitable candidate to fill the vacancy on the Audit Committee that will arise from Mr. Huang's resignation as soon as possible before January 1, 2025.

Further announcement will be made by the Company as and when appropriate and in accordance with the Listing Rules.

By order of the Board

Sirnaomics Ltd.

Yang (Patrick) Lu

Chairman and Non-Executive Director

Hong Kong, December 5, 2024

As at the date of this announcement, the Board comprises Dr. Poon Hung Fai as executive Director, Dr. Yang Lu (alias Patrick Lu), Mr. Mincong Huang and Mr. Jiankang Zhang as non-executive Directors, and Dr. Cheung Hoi Yu, Ms. Monin Ung and Ms. Shing Mo Han, Yvonne (alias Mrs. Yvonne Law) as independent non-executive Directors.