Sirnaomics Ltd. — Board/Management Information 2026

Jun 5, 2026

Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this announcement, make no representation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this announcement.

SIRNAOMICS LTD.

(Incorporated in the Cayman Islands with limited liability)

(Stock Code: 2257)

RESIGNATION OF NON-EXECUTIVE DIRECTOR, WITHDRAWAL OF RESOLUTION AT THE ANNUAL GENERAL MEETING AND CHANGES IN COMPOSITION OF BOARD COMMITTEES

Reference is made to the notice of the annual general meeting (the "Notice of AGM") of Sirnaomics Ltd. (the "Company") and the circular of the Company (the "Circular"), both dated May 29, 2026 in relation to, among others, the proposal for re-election of directors at the forthcoming annual general meeting of the Company (the "AGM") to be held on June 23, 2026. Unless otherwise specified, capitalised terms used in this announcement shall have the same meanings as those defined in the Circular and the Notice of AGM.

RESIGNATION OF NON-EXECUTIVE DIRECTOR

The board (the "Board") of directors (the "Director(s)") of the Company hereby announces that the Board has received a letter of resignation from Mr. Ouyang Yunlong ("Mr. Ouyang") to resign as a non-executive Director, a member of the audit committee of the Board (the "Audit Committee") and a member of the remuneration committee of the Board (the "Remuneration Committee") with effect from June 5, 2026, as Mr. Ouyang wishes to devote more time to his other commitments. Mr. Ouyang has confirmed that he has no disagreement with the Board and there is no other matter relating to his resignation that need to be brought to the attention of the shareholders of the Company or The Stock Exchange of Hong Kong Limited.

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The Board would like to express its sincere gratitude to Mr. Ouyang for his valuable contribution to the Company during his tenure in office.

WITHDRAWAL OF RESOLUTION AT THE ANNUAL GENERAL MEETING

The proposed resolution numbered 2(i) in respect of the re-election of Mr. Ouyang as Director as set out in the Notice of AGM and the proxy form for the AGM is no longer applicable and will not be put forward for consideration and approval by the Shareholders at the AGM. Save as disclosed above, all other proposed resolutions contained in the Notice of AGM and the proxy form for the AGM shall continue to be considered at the AGM, and the date, time and venue for holding the AGM shall remain unchanged.

The proxy form for the AGM already lodged by the Shareholders shall remain valid except that no poll will be conducted or counted for the proposed resolution numbered 2(i) at the AGM. No revised documents will be published by the Company.

CHANGES IN COMPOSITION OF BOARD COMMITTEES

The Board further announces that Dr. Yin Huijun, a non-executive Director, has been appointed as a member of the Audit Committee and the Remuneration Committee with effect from June 5, 2026.

By order of the Board

Sirnaomics Ltd.

Dr. Poon Hung Fai

Chairman and Executive Director

Hong Kong, June 5, 2026

As at the date of this announcement, the Board comprises Dr. Poon Hung Fai as executive Director, Dr. Yin Huijun as non-executive Director, and Mr. Wong Yu Shan Eugene, Dr. Zhang Peng and Ms. Lo Yee Hang as independent non-executive Directors.

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