Septerna, Inc. — Director's Dealing 2026

Feb 10, 2026

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Septerna, Inc. (SEPN)
CIK: 0001984086
Period of Report: 2026-02-06

Reporting Person: Wilson Mark Andrew (N/A)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2026-02-06	Stock Option (Right to Buy)	$25.41	A	165000	Acquired	2036-02-05	Common Stock (165000)	Direct

Footnotes

F1: 25% of the shares underlying this option will vest on January 5, 2027, and the remaining 75% of the shares underlying this option will vest in thirty-six substantially equal monthly installments thereafter, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.