PLUS THERAPEUTICS, INC. — Director's Dealing 2025

Aug 15, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: PLUS THERAPEUTICS, INC. (PSTV)
CIK: 0001095981
Period of Report: 2025-08-13

Reporting Person: Sims Andrew John Hugh MacIntyre (N/A)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-08-13	Stock Option (Right to Buy)	$0.5744	A	1379636	Acquired	2035-08-12	Common Stock (1379636)	Direct
2025-08-13	Restricted Stock Units	$	A	459878	Acquired		Common Stock (459878)	Direct

Footnotes

F1: The option vest over four years in equal 1/48th increments on each monthly anniversary of the issuance.

F2: The Restricted Stock Units (RSUs) awarded on August 13, 2025 vest over three years, with 1/3rd vesting on the first anniversary of the Grant Date and the remaining 2/3rds vesting in equal monthly installments over the following two years. The RSUs convert into shares of Common Stock upon vesting on a one for one basis.