PLUS THERAPEUTICS, INC. — Director's Dealing 2026

Feb 27, 2026

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: PLUS THERAPEUTICS, INC. (PSTV)
CIK: 0001095981
Period of Report: 2026-02-25

Reporting Person: Sims Andrew John Hugh MacIntyre (N/A)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2026-02-25	Restricted Stock Units	$0	A	349542	Acquired		Common Stock (349542)	Direct
2026-02-25	Stock Option (Right to Buy)	$0.28	A	349541	Acquired	2036-02-24	Common Stock (349541)	Direct

Footnotes

F1: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock. The RSUs awarded vest ratably over twelve quarters in substantially equal 1/12th increments, commencing with 1/12th vesting on April 1, 2026 and the remainder vesting quarterly thereafter.

F2: The options vest over four years in substantially equal 1/48th increments on each monthly anniversary of the issuance and vest on a change of control in accordance with the Optionee's employment agreement.