Oxurion NV — Major Shareholding Notification 2025

May 15, 2025

Oxurion Receives Transparency Notifications from Atlas Special Opportunities II LLC

Leuven, BELGIUM – May 15, 2025 – 06:00 PM CET - Oxurion NV (Euronext Brussels: OXUR), a biopharmaceutical company headquartered in Leuven, today announced that, pursuant to Belgian Transparency legislation¹ it has received transparency notifications as follows:

Oxurion received a transparency notification on May 15, 2025, from Atlas Special Opportunities II, LLC indicating that as of May 8, 2025, it held 202,731 shares of the then outstanding 4,634,663 shares, and therefore crossed under the threshold (5%) by virtue of the selling of voting securities.

Oxurion received a transparency notification on May 15, 2025, from Atlas Special Opportunities II, LLC indicating that as of May 12, 2025, it held 1,724,103 shares of the then outstanding 6,156,035 shares, and therefore crossed above the threshold (25%) by virtue of the purchase of voting securities.

About Oxurion

Oxurion (Euronext Brussels: OXUR) is engaged in developing next-generation standard of care ophthalmic therapies for the treatment of retinal disease. Oxurion is based in Leuven, Belgium. More information is available at www.oxurion.com.

Important information about forward-looking statements

Certain statements in this press release may be considered "forward-looking". Such forward-looking statements are based on current expectations, and, accordingly, entail and are influenced by various risks and uncertainties. The Company therefore cannot provide any assurance that such forward-looking statements will materialize and does not assume any obligation to update or revise any forward-looking statement, whether as a result of new information, future events, or any other reason. Additional information concerning risks and uncertainties affecting the business and other factors that could cause actual results to differ materially from any forwardlooking statement is contained in the Company's Annual Report. This press release does not constitute an offer or invitation for the sale or purchase of securities or assets of Oxurion in any jurisdiction. No securities of Oxurion may be offered or sold within the United States without registration under the U.S. Securities Act of 1933, as amended, or in compliance with an exemption therefrom, and in accordance with any applicable U.S. state securities laws.

For further information please contact:

Oxurion NV Pascal Ghoson Chief Executive Officer Pascal.ghoson@oxurion.com

________

1. Article 14, first paragraph, of the Law of 2 May 2007 on disclosure of major holdings.

ANNEX 1

FSMA	FINANCIAL SERVICES AND MARKETS AUTHORITY	Transparency notification Form TR-1 BE PART I
1) Status of the notification
	Final
2) Issuer
Identification number 0881-620-924	Name OXURION
3) Reason for the notification
	Acquisition or disposal of voting securities or voting rights
4) Notification by
	A person that notifies alone
5) Persons subject to the notification requirement
	Name	Address (for legal entities)
	Atlas Special Opportunities II LLC	2500 Westchester Avenue, Suite 401, Purchase, NY 10577
	6) Persons that dispose of votinq rights (only to be filled in if art. 7 of the Law applies)
	Name	Address (for legal entities)
B	Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6	Part II
7) Date on which the threshold is crossed
		08/05/2025 (DDMMYYYY)
8) Threshold that is crossed (in %)
	5
		If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10
9) Denominator
	4,634,663
	P Please enter the denominator before filling in the data
10) Notified details,
A) Voting rights	Previous notification	After the transaction

A) voung rights	r revious notification	And the transavivi
	# of voting rights	# of voting rights		% of voting rights
Holders of woting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
Atlas Special Opportunities II LLC	364,328	202.731		4.37%
	TOTAL	202,731	0	4.37%	0.00%

B) Equivalent financial instruments	After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							+
	TOTAL			0	0.00%
The totals will be updated once you have clicked on 19
TOTAL (A & B)				# of voting rights % of voting rights
			CALCULATE	202,731	4.37%

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

	Atlas Special Opportunities II LLC is not a controlled entity.
12) In case of proxy voting for only one GM
Holder		will cease to hold / will hold again	0 voting rights as of	(DDMM/YYYY)
13) Additional information
denominator = 4,634,663). denominator = 4,634,663), denominator = 4,634,663). denominator = 4,634,663), denominator = 4,634,663), denominator = 4,634,663).	On 25 Apr 2025 (with setternet date on 20 pm I LC sod 500 shares n Oxinon N, as a result in its stareboling deceased o 33,228 shares ( 7.88% On 28 And 2020 (with setternet date on 30 pril 2020) Atas Special Open N, as a result it shareholing decessed b 33,00 shares ( 7.65%, On 29 April settlement date on 2 May 2025), Attas Special Opportunities I LLC solo 61 shares in Cruicin its stareholing deceased of 30,025 stares (= 7.6%, On 30 Ann 2025 (with settenent date on 5 May 2025), Atas Special Operior N, as a result of which its stareholing decreased a 30,425 shares (= 7.8%, On 2 May 2025 (with settenent cate on 0 May 2025), Atas Special Open 10, as a result of which its stareholding decreased of 30,424 shares (= 7.8%, On 6 May 2025 (with setternent cate on 8 May 2025). Altas Special of Month N, as a result of which its starending decreased o 202, 31 shares ( +.37%,
Done at New York
On		13/05/2025 (DD/MMYYYY)
Name & capacity Patrick Vance, Proxyholder		Signature	Signed by: 9A8C4789B05442E

For security reasons, the unsiened form in xlsx format should
be transmitted to trp.fin@fsma.be. You can do this manually
OR if you have MS Outlook at your disposal via th

In addition, a signed copy in PDF format should also be
transmitted.

ANNEX 2

FSMA FINANCIAL SERVICES AND MARKETS AUTHORITY		Transparency notification Form TR-1 BE PART I
1) Status of the notification
Final
2) Issuer
Name OXURION
Identification number 0881-620-924
3) Reason for the notification
	Acquisition or disposal of voting securities or voting rights
4) Notification by
	A person that notifies alone
5) Rersons subiect to the notification requirement
	Name	Address (for legal entities)
	Atlas Special Opportunities II LLC	2500 Westchester Avenue, Suite 401, Purchase, NY 10577
6) Persons that dispose of voting rights (only to be filled in if art. 7 of the Law applies)
	Name	Address (for legal entities)
T	Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6	Part II
7) Date on which the threshold is crossed
		12/05/2025 (DD/MMYYYYY)
8) Threshold that is crossed (in %)
	25
		If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10
9) Denominator
	6,156,035
	Please enter the denominator before filling in the data
10) Notified details,

A) Voting rights	Previous notification	After the transaction
	# of voting rights		# of voting rights	% of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
Atlas Special Opportunities II LLC	202,731	1,724,103		28.01%
TOTAL		1,724,103	0	28.01%	0.00%

-

B) Equivalent financial instruments	After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							+
	TOTAL			0	0.00%
The totals will be updated once you have clicked on P

TOTAL (A & B)			# of voting rights % of voting rights
	CALCULATE	1,724,103	28.01%

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

12) In case of proxy voting for only one GM

	Holder		will cease to hold / will hold again		voting rights as of
--	--------	--	-----------------------------------------	--	---------------------	--	--

13) Additional information

On 8 May 2025 (with setternet date on 12 May 2020). Alta Special Operation N, as a result of which is shareholding inceased b 1,724,103 shares (=
28.01%, denominator = 6,156,035).

	Done at New York
On		13/05/2025 (DD/MMYYYYY)
	Name & capacity Patrick Vance, Proxyholder

For security reasons, the unsigned form in xlsx format should
be transmitted to trp.fin@fsma.be. You can do this manually
OR if you have MS Outlook at your disposal via th

(DDMM/YYYY)

In addition, a signed copy in PDE format should also be
transmitted.