Oxurion NV — Major Shareholding Notification 2023

Oct 30, 2023

Oxurion Receives Transparency Notifications from Atlas Special Opportunities LLC

October 30, 2023

Regulated Information

Leuven, BELGIUM, Boston, MA, US – October 30, 2023 – 8.00 AM CET Oxurion NV (Euronext Brussels: OXUR), a biopharmaceutical company developing next generation standard of care ophthalmic therapies, with clinical stage assets in vascular retinal disorders, today announced that, pursuant to Belgian Transparency legislation1 it has received transparency notifications as follows:

Oxurion received a first transparency notification on October 27, 2023, from Atlas Special Opportunities, LLC indicating that as of October 20, 2023, it held 124,268,139 shares of the then outstanding 2,879,124,260 shares, and therefore crossed above the threshold (3%) by virtue of the acquisition of voting securities. See Annex 1.

Oxurion received a second transparency notification on October 27, 2023, from Atlas Special Opportunities, LLC indicating that as of October 23, 2023, it held 31,523,659 shares of the then outstanding 2,879,124,260 shares, and therefore crossed under the threshold (3%) by virtue of the sale of voting securities. See Annex 2.

About Oxurion

Oxurion (Euronext Brussels: OXUR) is a biopharmaceutical company developing next generation standard of care ophthalmic therapies, which are designed to improve and better preserve vision in patients with retinal disorders including diabetic macular edema (DME), the leading cause of vision loss in working-age people, as well as other conditions. Oxurion intends to play an important role in the treatment of retinal disorders, including the successful development of THR-149, its novel therapeutic for the treatment of DME. THR-149 is a potent plasma kallikrein inhibitor being developed as a potential new standard of care for the up to 50% of DME patients showing suboptimal response to anti-VEGF therapy. Oxurion is headquartered in Leuven, Belgium, with corporate operations in Boston, MA. More information is available at www.oxurion.com.

Important information about forward-looking statements

Certain statements in this press release may be considered "forward-looking". Such forward-looking statements are based on current expectations, and, accordingly, entail and are influenced by various risks and uncertainties. The Company therefore cannot provide any assurance that such forward-looking statements will materialize and does not assume any obligation to update or revise any forward-looking statement, whether as a result of new information, future events, or any other reason. Additional information concerning risks and uncertainties affecting the business and other factors that could cause actual results to differ materially from any forward-looking statement is contained in the Company's Annual Report. This press release does not constitute an offer or invitation for the sale or purchase of securities or assets of Oxurion in any jurisdiction. No securities of Oxurion may be offered or sold within the United States without registration under the U.S. Securities Act of 1933, as amended, or in compliance with an exemption therefrom, and in accordance with any applicable U.S. state securities laws.

For further information please contact:

Oxurion NV	US
Tom Graney	Conway Communications
Chief Executive Officer	Mary T. Conway
Tel: +32 16 75 13 10	mtconway@conwaycommsir.com
tom.graney@oxurion.com
Michael Dillen
Chief Business Officer
Tel: +32 16 75 13 10
michael.dillen@oxurion.com

________

^1. Article 14, first paragraph, of the Law of 2 May 2007 on disclosure of major holdings.

FSMA FINANCIAL SERVICES AND MARKETS AUTHORITY	Transparency notification Form TR-1 BE PART I
1) Status of the notification
Final
2) Issuer
Name OXURION Identification number 0881-620-924
3) Reason for the notification
Acquisition or disposal of voting securities or voting rights
4) Notification by
A person that notifies alone
5) Persons subject to the notification requirement
Name	Address (for legal entities)
Atlas Special Opportunities LLC	2500 Westchester Avenue, Suite 401, Purchase, NY 10577
6) Persons that dispose of voting rights (only to be filled in if art. 7 of the Law applies)
Name	Address (for legal entities)
persons referred to in Sections 5 and 6	Please continue entering the information in part II concerning the Part II
7) Date on which the threshold is crossed
	20/10/2023 (DD/MM/YYYY)
8) Threshold that is crossed (in %)
	If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10

9) Denominator

2,879,124,260 Please enter the denominator before filling in the data

10) Notified details

A) Voting rights	Previous notification	After the transaction
	# of voting rights	% of voting rights # of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
Atlas Special Opportunities LLC	52.513.222	124.268.139		4.32%	0.00%
	TOTAL	124,268,139		4.32%	0.00%

$\pm$

Start with "groups" of holders. Add subtotals with $\Sigma$ , and then finish with the persons who are "alone".
For groups, start with the ultimate controlling natural person or legal entity.
The totals, subtotals and % will b

-
Sign Envelope ID: 2DA63517-76BC-4E81-98B1-87322EA2DD2B

B) Equivalent financial instruments			After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							┻
	TOTAL			O	$0.00\%$

The totals will be updated once you have clicked on

TOTAL (A & B)			# of voting rights % of voting rights
	CALCULATE	124,268,139	4.32%

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

12) In case of proxy voting for only one GM

will cease to hold / Holder voting rights as of will hold again			$\sim$

13) Additional information

On 20 October 2023, Atlas Special Opportunities LLC held 3,495,193 shares (= 1.27%, numerator = 2,758,351,314) in Oxurion NV. On the same day, Atlas Special Opportunities converted 120,772,946 shares in Oxurion NV, as a result of which its shareholding increased to 124,268,139 (= 4.32%, numerator = 2,879,124,260).

	Done at New York
On		25/10/2023 (DD/MM/YYYY)
	Name & capacity Patrick Vance, proxyholder

ANNEX 2

FSMA FINANCIAL SERVICES AND MARKETS AUTHORITY	Transparency notification Form TR-1 BE PARTI
1) Status of the notification
Final
2) Issuer
Name OXURION Identification number 0881-620-924
3) Reason for the notification
Acquisition or disposal of voting securities or voting rights
Downward crossing of the lowest threshold
4) Notification by
A person that notifies alone		$+$
5) Persons subject to the notification requirement
Name	Address (for legal entities)
Atlas Special Opportunities LLC	2500 Westchester Avenue, Suite 401, Purchase, NY 10577	$+$
6) Persons that dispose of voting rights (only to be filled in if art. 7 of the Law applies)
Name	Address (for legal entities)
Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6	Part II
7) Date on which the threshold is crossed
	23/10/2023 (DD/MM/YYYY)
8) Threshold that is crossed (in %)
w	If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10

9) Denominator

2,879,124,260

Please enter the denominator before filling in the data

10) Notified details

A) Voting rights	Previous notification	After the transaction
	# of voting rights	% of voting rights # of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
Atlas Special Opportunities LLC	124,268,139	31,523,659		1.09%	0.00%
	TOTAL	31,523,659		1.09%

$\pm$

Start with "groups" of holders. Add subtotals with $\Sigma$ , and then finish with the persons who are "alone".
For groups, start with the ultimate controlling natural person or legal entity.
The totals, subtotals and % will be

Sign Envelope ID: 2DA63517-76BC-4E81-98B1-87322EA2DD2B

B) Equivalent financial instruments			After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
							÷
	TOTAL

The totals will be updated once you have clicked on

TOTAL (A & B)			# of voting rights % of voting rights
	CALCULATE	31,523,659	1.09%

Atlas Special Opportunities LLC is not a controlled entity.

12) In case of proxy voting for only one GM

			(DD/MM/YYYY)
Holder	will cease to hold / will hold again	voting rights as of

13) Additional information

On 20 October 2023, Atlas Special Opportunities LLC held 124,268,139 shares (= 4.32%) in Oxurion NV. On the same day, Atlas Special Opportunities LLC sold 3,495,193 shares in Oxurion NV, as a result of which its shareholding decreased to 120,772,946 shares (= 4.18%). On the same day, Atlas Special Opportunities LLC sold 19,520,671 shares in Oxurion NV, as a result of which its shareholding decreased to 101.252.275 shares (= 3.51%). On 23 October 2023, Atlas Special Opportunities LLC sold 69,728,616 shares in Oxurion NV, as a result of which its shareholding decreased to 31,523,659 shares (= 1.09%).

Attachments

• $\frac{\epsilon}{N}$