OPKO Health Inc. — Proxy Solicitation & Information Statement 2017

Apr 29, 2017

SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Filed by the Registrant ☒ Filed by a party other than the Registrant ☐

Check the appropriate box:

• ☐ Preliminary Proxy Statement
• ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))
• ☐ Definitive Proxy Statement
• ☒ Definitive Additional Materials
• ☐ Soliciting Material under 240.14a-12

OPKO HEALTH, INC.

(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

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☐ Fee paid previously with preliminary materials.

• ☐ Check box if any part of the fee is offset as provided by Exchange Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.
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(4) Date Filed:

		*** Exercise Your Right to Vote ***
Important Notice Regarding the Availability of Proxy Materials for the Shareholder Meeting to Be Held on June 15, 2017
ОРКО HEALTH, INC.		Meeting Information Meeting Type: Annual Meeting For holders as of: April 20, 2017 Time: 10:00 AM EST Date: June 15, 2017 Location: 4400 Biscayne Blvd.	B
BROKER LOGO HERE		Miami, FL 33137	AROODE
Return Address Line 1 Return Address Line 2 Return Address Line 3 51 MERCEDES HAY		You are receiving this communication because you hold shares in the above named company. This is not a ballot. You cannot use this notice to vote
EDGEWOOD NY 11717 Investor Address Line Investor Address Line 2 Investor Address Line ਤੇ Investor Address Line 4	1 12	these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at www.proxyvote.com or easily request a paper copy (see reverse side).
Investor Address Line 5 John Sample 1234 ANYWHERE STREET ANY CITY, ON A1A 1A1	2	We encourage you to access and review all of the important information contained in the proxy materials before voting.
		See the reverse side of this notice to obtain proxy materials and voting instructions.
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How To Vote

Please Choose One of the Following Voting Methods

Vote In Person: If you choose to vote these shares in person at the meeting you must request a "legal proxy." To do so, please follow the instructions at www.broxyvote.com or request a paper copy of the materials, which will contain the appropriate instructions. Many shareholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance.

Vote By Internet: To vote now by Internet, go to www.proxyvote.com. Have the information that is printed in the box Internal Use marked by the arrow -> |xxxx xxxx xxxx xxxx | available and follow the instructions.

Only

Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a voting instruction form.

Voting items The Board of Directors recommends that you vote FOR the following:
1. Election of Directors
Nominees
Phillip Frost, M.D. 03 Steven D. Rubin 04 Richard M. Krasno, Ph.D 05 Richard A. Lerner, M.D. 01 02 Jane H. Hsiao, Ph.D. ાદ 07 Richard C. Pfenniger 08 Alice Yu, M.D., Ph.D. John A. Paganelli	B A
The Board of Directors recommends you vote FOR the following proposal (s) :
2 A non-binding advisory vote to approve the compensation paid to named executive officers of the Company ("Say on Pay").	R C 0
The Board of Directors recommends you vote 1 YEAR on the following proposal :	D
3 A non-binding advisory vote on the frequency with which stockholders are provided an advisory vote on Say on Pay .	E
NOTE: In their discretion, the proxy holders are authorized to vote upon such other matters as may properly come before the meeting or any postponement or adjournment thereof.

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Voting Instructions

RI.0.1.15

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