OPKO Health Inc. — M&A Activity 2014

Apr 23, 2014

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C002����� ���', ����2PublicOPKO HEALTH, INC10017Corporation no: 2279206Stock Exchange/Market: NYSE2893380Biscayne Boulevard 4400 , MIAMI, FLORIDA, U.S.A 19808 , ,Tel: 13055754100 , Fax: 13055754140E.mail address: Contact@Opko.ComReported via MAGNA: 23/04/2014              Time of broadcast: 08:51 08:44:02

Company site:		Www.Opko.Com

Reference: 2014-02-048426

Israel Securities Authority		Tel Aviv Stock Exchange
www.isa.gov.il		www.tase.co.il

Immediate ReportRegulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

The corporation is a foreign private issuer as defined by U.S. Securities Laws.
Attached hereto is a report on A Stock Purchase Agreement by and among the Company, OPKO Holdings Israel Ltd, Inspiro Medical Ltd, and certain shareholders of Inspiro. ����� ����� ���� ����� �� ���� ����� ����� ��� �����, �������� ����� ��"� ����� ������ �� �������� ����� ��"�
PR23414_isa.pdf

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
Previous names of reporting entity:
Date of revision of form structure: 02/03/2014
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Name of the Signatory: : Gerzi Ilan , Position of Signatory in the reporting corporation: Legal Adviser , Name of Employer Company: PEARL COHEN ZEDEK LATZER BARATZ .
Azrieli, Round Tower 18f Telephone: 03-6073777 , Facsimile: 03-6073778 , E-mail: IGERZI@PEARLCOHEN.COM 1