OPKO Health Inc. — Director's Dealing 2015

Oct 1, 2015

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C002����� ���', ����2PublicOPKO HEALTH, INC10802Corporation no: 2279206Stock Exchange/Market: NYSE2893380Biscayne Boulevard 4400 , MIAMI 19808 , FLORIDA , USATel: 13055754100 , Fax: 13055754140E.mail address: Contact@Opko.ComReported via MAGNA: 01/10/2015              Time of broadcast: 14:27 14:27:34

Company site:		Www.Opko.Com

Reference: 2015-02-127200

Israel Securities Authority		Tel Aviv Stock Exchange
www.isa.gov.il		www.tase.co.il

Immediate ReportRegulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

The corporation is a foreign private issuer as defined by U.S. Securities Laws.
Attached hereto is a report on interested party transaction
20151001Form4Signed.pdf

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
Previous names of reporting entity:
Date of revision of form structure: 16/09/2015
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Name of the Signatory: : Philip Yifat , Position of Signatory in the reporting corporation: General Counsel , Name of Employer Company: .
Golda Meir Telephone: 08-9300051 , Facsimile: 08-9300091 , E-mail: yphilip@opko.com 1