OPKO Health Inc. — Director's Dealing 2014

Apr 16, 2014

FORM 4

☐ Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person*
FROST PHILLIP M.D. ET AL
OPKO Health, Inc. (OPK)
☐ Director ☐ 10% Owner
☐ Officer (give title below) ☐ Other (specify below)
Officer: CEO & Chairman
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(Last) (First) (Middle)
OPKO Health, Inc. 4400 Biscayne Blvd.
04/14/2014
(Street)
Miami FL 33137
• Form filed by One Reporting Person
• Form filed by More than One Reporting Person
(City) (State) (Zip)
Table I — Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security
(Instr 3.)
(MM/DD/YYYY)
(MM/DD/YYYY)
(Instr. 8)
(Instr. 3, 4 and 5)
Following Reported Transactions
(Instr. 3 and 4)
Direct (D) or Indirect (I)
(Instr. 4)
Code

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FORM 4 (continued)

Table II — Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr.3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (MM/DD/YYYY)	3A. Deemed Execution Date (MM/DD/YYYY)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (MM/DD/YYYY)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)
				Code	V	Amount	(A) or (D)	Exercisable Date	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$8.37	04/14/2014		A		400000	A	(1)	04/13/2024	Common Stock	400000	$0.00	400000

Explanation of Responses: See attached footnotes page.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

• If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations

See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Philip Frost, M.D. 4/15/2014

**Signature of Reporting Person

Date

Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

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FORM 4 (continued)

Explanation of Responses

(1) This option will vest in four equal annual installments beginning April 14, 2015.