OPKO Health Inc. — Director's Dealing 2014

Jun 15, 2014

FORM 4

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* 2. Issuer Name and Ticker or Trading Symbol 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Baron Robert A OPKO Health, Inc. (OPK) Director 10% Owner (Last) (First) (Middle) 3. Date of Earliest Transaction (MM/DD/YYYY) Officer Other (give title below) (specify below) 2401 Ingleside Avenue Suite 1D 06/12/2014 (Street) 4. If Amendment, Date Original Filed (MM/DD/YYYY) 6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person Cincinnati OH 45206 Form filed by More than One Reporting Person (City) (State) (Zip) Table I — Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1. Title of Security 2. Transaction 2A. Deemed 3. Transaction 4. Securities Acquired (A) or Disposed of (D) 5. Amount of 6. Ownership 7. Nature of Indirect (Instr 3.) Date Execution Code (Instr. 3, 4 and 5) Securities Form: Beneficial (MM/DD/YYYY) Date, if any (Instr. 8) Beneficially Direct (D) Ownership (MM/DD/YYYY) Owned or (Instr. 4) Following Indirect (I) Reported (Instr. 4) Transactions (Instr. 3 and Code V Amount (A) or (D) Price 4)

FORM 4 (continued)

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----- Start of picture text ----- Table II — Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)1. 2. 3. 3A. 4. 5. 6. 7. 8. 9. 10. 11.Title of Derivative Security Conversion Transaction Deemed Transaction Number of Date Exercisable and Title and Amount Price of Number of Ownership Nature of(Instr.3) or Date Execution Date Code Derivative Expiration Date of Underlying Derivative Derivative Form of IndirectExercise (MM/DD/YYYY) (MM/DD/YYYY) (Instr. 8) Securities (MM/DD/YYYY) Securities Security Securities Derivative BeneficialPrice of Acquired (Instr. 3 and 4) (Instr. 5) Beneficially Securities: OwnershipDerivative (A) or Owned Direct (D) (Instr. 4)Security Disposed Following orof (D) Reported Indirect (I)(Instr. 3, 4 Transaction(s) (Instr. 4)and 5) (Instr. 4)Amountor(A) Numberor Exercisable Expiration ofCode V Amount (D) Date Date Title SharesStock Option (Right to Buy) $9.10 06/12/2014 A 20000 A 06/12/2015 06/11/2024 Common 20000 $0.00 20000 Dstock----- End of picture text -----

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.	Adam Logal, Attorney-in-Fact	6/13/2014
* If the form is filed by more than one reporting person,_see_Instruction 4(b)(v).** Intentional misstatements or omissions of facts constitute Federal Criminal Violations	___________________________________**Signature of Reporting Person	______Date
_See_18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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