MESOBLAST LTD — Share Issue/Capital Change 2016

Apr 18, 2016

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19 April 2016

Manager Market Announcements Office ASX Limited Exchange Centre 20 Bridge Street Sydney NSW 2000

Dear Sir or Madam

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Release of shares from voluntary escrow

Mesoblast Limited (ASX Code: MSB) gives notice in accordance with ASX Listing Rule 3.10A that 15,298,837 ordinary shares, which are subject to voluntary escrow arrangements, will be released from escrow on 5 May 2016.

Yours sincerely

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Charlie Harrison

Senior Legal Counsel and Company Secretary