MESOBLAST LTD — Director's Dealing 2022

Sep 19, 2022

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name of entity MESOBLAST LIMITED ABN 68 109 431 870

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	William Burns
Date of last notice	24 June 2020

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Indirect
Nature of indirect interest(including registered holder)Note: Provide details of the circumstances giving rise to the relevantinterest.	Registered holder is UBS (as custodian forthe director)
Date of change	13 September 2022
No. of securities held prior to change	63,000 ordinary shares220,000 options
Class	Ordinary shares
Number acquired	22,000 ordinary shares
Number disposed	0
Value/ConsiderationNote: If consideration is non-cash, provide details and estimatedvaluation	AU$20,020.00 (AU$ 0.91 per share)
No. of securities held after change	85,000 ordinary shares220,000 options

• See chapter 19 for defined terms.

01/01/2011

Appendix 3Y Page 1

Appendix 3Y Change of Director’s Interest Notice

Nature of changeExample: on-market trade, off-market trade, exercise of options, issueof securities under dividend reinvestment plan, participation in buy-back	Nature of changeExample: on-market trade, off-market trade, exercise of options, issueof securities under dividend reinvestment plan, participation in buy-back	On market share purchase
art 2 – Change of director’s interests in contractsote: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should beisclosed in this part.
Detail of contract	Not Applicable
Nature of interest	Not Applicable
Name of registered holder(if issued securities)	Not Applicable
Date of change	Not Applicable
No. and class of securities to whichinterest related prior to changeNote: Details are only required for a contract inrelation to which the interest has changed	Not Applicable
Interest acquired	Not Applicable
Interest disposed	Not Applicable
Value/ConsiderationNote: If consideration is non-cash, provide details andan estimated valuation	Not Applicable
Interest after change	Not Applicable

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Part 3 –[+] Closed period

Were the interests in the securities or contracts detailedabove traded during a+closed period where prior writtenclearance was required?	No
If so, was prior written clearance provided to allow thetrade to proceed during this period?	Not Applicable
If prior written clearance was provided, on what date wasthis provided?	Not Applicable

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011