MESOBLAST LTD — Director's Dealing 2008

Apr 23, 2008

Appendix 3Y Change of Director's Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX's property and may be made public.

Introduced 30/9/2001.

Name of eatity:	Bond Street Custedians Limited (Brian Jamieson - 802015536) Level 26, 20 Bond Street, Sydney NSW 2000
LABN.	65 508 799 106

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	BRIAN JAMESON
Date of last notice	$N0N^2$

Part 1 - Change of director's relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: in the case of a company, interests which come within paragraph (i) of the dafinition of "notifiable interest of a director" should be disclosed in this own.

Direct or indirect interest	DIRECT
Nature of indirect interest (including registered holder) Note: Provide dotalls of the nicomstances giving rise to the relavant interest.
Date of change
No. of securities held prior to change	NIL
Class
Number acquired	ORDINALY 125000
Number disposed
Value/Consideration Note: If consideration is non-cash, provide details and ortimated valuation	890625
No. of securities held after change	125,660

Appendix 3Y Page 1

^- See chapter 19 for defined terms.

Appendix 3Y Change of Director's Interest Notice

Nature of change Example: on-nurrical trade, off-reastint trade, exercise of ephone, issue of ecomines under dividend reinvestment gian, participation in buy-back		ON MARKET DURUMS
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------	--	------------------	--

Part 2 - Change of director's interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director" should be sixelosed.
In this part,

Detail of contract
Nature of interest
Name of registered holder (if issued securities)
Date of change
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed
Interest acquired
Interest disposed
Vaine/Consideration Note: If consideration is non-cash, provide details and an estimated valuation
Interest after change

⁺ See chapter 19 for defined terms.