MESOBLAST LTD — Capital/Financing Update 2022

Aug 11, 2022

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12 August 2022

The Manager Company Notices Section ASX Limited Level 4, North Tower, Rialto Towers 525 Collins Street MELBOURNE VIC 3000

Dear Sir/Madam

Notice under section 708A(5)(e) of the Corporations Act 2001 (Cth)

This notice is given by Mesoblast Limited ACN 109 431 870 ( Mesoblast ) under section708A(5)(e) of the Corporations Act 2001 (Cth) ( Corporations Act ).

Mesoblast has today issued 86,666,667 fully paid ordinary shares in Mesoblast (the Shares ) at an issue price of US$0.52 (A$0.75) per Share to sophisticated and professional investors under the private placement announced on Tuesday, 9 August 2022.

Mesoblast advises that:

1. the Shares were issued without disclosure to investors under Part 6D.2 of the Corporations Act;

2. this notice is being given under section 708A(5)(e) of the Corporations Act;

3. as at the date of this notice, Mesoblast has complied with:

   • a. the provisions of Chapter 2M of the Corporations Act as they apply to Mesoblast; and

   • b. section 674 of the Corporations Act; and

4. as at the date of this notice, there is no excluded information of the type referred to in sections 708A(7) and 708A(8) of the Corporations Act

Release authorised by the Chief Executive Officer.

Yours faithfully

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Paul Hughes Joint Company Secretary Mesoblast Limited

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