MESOBLAST LTD — Capital/Financing Update 2021

Feb 25, 2021

Market Announcement

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26 February 2021

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Mesoblast Limited (ASX: MSB) – Trading Halt

Description

The securities of Mesoblast Limited (‘MSB’) will be placed in trading halt at the request of MSB, pending it releasing an announcement. Unless ASX decides otherwise, the securities will remain in trading halt until the earlier of the commencement of normal trading on Tuesday, 2 March 2021 or when the announcement is released to the market.

Issued by

Melissa Kostopoulos

Compliance Adviser, Listings Compliance (Melbourne)

Market Announcement 1/1 ASX Customer Service Centre 131 279 | asx.com.au

26 February 2021 ASX Limited

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26 February 2021

Ms Melissa Kostopoulos Adviser, Listings Compliance (Melbourne) ASX Compliance Pty Limited Level 4 Rialto North Tower 525 Collins Street Melbourne VIC 3000

Copy: tradinghaltsmelbourne@asx.com.au

Dear Melissa,

Request for trading halt for Mesoblast Limited (ASX: MSB)

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Pursuant to ASX Listing Rule 17.1, Mesoblast Limited ACN 109 431 870 (ASX: MSB; NASDAQ: MESO) (the Company ) requests a trading halt in its securities effective immediately pending an announcement by the Company in relation to a proposed private placement to a targeted industry investor.

For the purposes of Listing Rule 17.1, the Company provides the following information:

• (a) the trading halt is requested pending an announcement in relation to the matters above;

• (b) the Company requests that the trading halt continues until the earlier of it making an announcement regarding the matters above and the commencement of trading on Tuesday, 2 March 2021; and

• (c) the Company is not aware of any reason why the trading halt should not be granted or of any other information necessary to inform the market about the trading halt.

Yours sincerely

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Niva Sivakumar Company Secretary Mesoblast Limited