IMMUTEP LIMITED — Major Shareholding Notification 2021

Nov 16, 2021

604 page 1/2 15 July 2001

Form604

Corporations Act 2001 Section 671B

Notice of change of interests of substantial holder

To Company Name/Scheme – Immutep Limited

ACN/ ARSN 009 237 889

1. Details of substantial holder (1)

Name The Bank of New York Mellon Corporation ( BNYMC ) and each Group Entity listed in Annexure A ( Group Entity ), (together BNYMC Group )

ACN/ARSN (if applicable)

There was a change in the interests of the Substantial holder on 15 November 2021 The previous notice was given to the company on 02 August 2021 The previous notice was dated 30 July 2021

2. Previous and present voting power

The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in when last required, and when now required, to give a substantial holding notice to the company or scheme, are as follows:

Classof securities(4)	Previous notice		Present notice
	Person's votes	Votingpower (5)	Person's votes	Votingpower (5)
Ordinary shares	279,232,349	32.82%	263,793,069*	30.89%*

• See Note 1 in Annexure C

3. Changes in relevant interests

Particulars of each change in, or change in the nature of, a relevant interest of the substantial holder or an associate in voting securities of the company or scheme, since the substantial holder was last required togivea substantial holding notice to thecompany or scheme are as follows:

Date of change	Person whose relevant interest changed	Nature of change(6)	Consideration giveninrelation tochange(7)	Class and number of securities affected	Person's votes affected
See Annexure B

4. Present relevant interests

Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows:

Holder of relevant interest	Registered holder of securities	Person entitled to be registered	Nature of relevant interest (6)	Class and number of securities	Person's votes
See Annexure C

604 page 2/2 15 July 2001

5. Changes in association

The persons who have become associates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder in relation to voting interests in the company or scheme are as follows:

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Name and ACN/ARSN (if applicable) Nature of association
BNYMC and each Group Entity Each Group Entity is an associate of BNYMC pursuant to section 12(2)(a) of the
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Corporations Act 2001 (Cth) as each entity is directly or indirectly owned and controlled by BNYMC.

6. Addresses

The addresses of persons named in this form are as follows:

Name	Address
The Bank of New York Mellon Corporation	240 Greenwich Street, New York, NY 10286 USA
Each Group Entity	240 Greenwich Street, New York, NY 10286 USA

Signature

print name Kevin Lockhart capacity[Attorney-In-Fact ] sign here Date 16 November 2021

Annexure A

This is Annexure A of 1 page referred to in Form 604 Notice of Change of Interests of Substantial Holder given by The Bank of New York Mellon Corporation and its related bodies corporate

The Bank of New York Mellon Corporation is the ultimate parent company of a corporate group comprised of a large number of operating and holding companies. Details of the entities directly owned and controlled by The Bank of New York Mellon Corporation are listed below.

• The Bank of New York Mellon

• Pershing Group LLC

• Pershing LLC

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print name Kevin Lockhart capacity Attorney-In-Fact
sign here date __ 16 November 2021 __
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Annexure B

This is Annexure B of 1 page referred to in Form 604 Notice of Change of Interests of Substantial Holder given by The Bank of New York Mellon Corporation and its related bodies corporate

Changes in relevant interests

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Class and number of
Person whose relevant interest Consideration given in Person's votes
Date of change Nature of Change securities affected
changed relation to change affected
(Ordinary Shares)
02-Aug-21 The Bank of New York Mellon Transfer out of Securities N/A (450,000) (450,000)
03-Aug-21 The Bank of New York Mellon Transfer out of Securities N/A (1,050,000) (1,050,000)
05-Aug-21 The Bank of New York Mellon Deposit of Securities N/A 38,510 38,510
11-Aug-21 The Bank of New York Mellon Transfer out of Securities N/A (100,000) (100,000)
16-Aug-21 The Bank of New York Mellon Transfer out of Securities N/A (60,000) (60,000)
17-Aug-21 The Bank of New York Mellon Transfer out of Securities N/A (100,000) (100,000)
18-Aug-21 The Bank of New York Mellon Transfer out of Securities N/A (300,000) (300,000)
19-Aug-21 The Bank of New York Mellon Transfer out of Securities N/A (100,000) (100,000)
23-Aug-21 The Bank of New York Mellon Transfer out of Securities N/A (530,000) (530,000)
02-Sep-21 The Bank of New York Mellon Deposit of Securities N/A 13,000 13,000
08-Sep-21 The Bank of New York Mellon Deposit of Securities N/A 100,000 100,000
10-Sep-21 The Bank of New York Mellon Deposit of Securities N/A 300,000 300,000
10-Sep-21 The Bank of New York Mellon Transfer out of Securities N/A (100,000) (100,000)
15-Sep-21 The Bank of New York Mellon Transfer out of Securities N/A (220,000) (220,000)
16-Sep-21 The Bank of New York Mellon Transfer out of Securities N/A (400,000) (400,000)
17-Sep-21 The Bank of New York Mellon Transfer out of Securities N/A (200,000) (200,000)
20-Sep-21 The Bank of New York Mellon Transfer out of Securities N/A (300,000) (300,000)
21-Sep-21 The Bank of New York Mellon Transfer out of Securities N/A (100,000) (100,000)
22-Sep-21 The Bank of New York Mellon Transfer out of Securities N/A (450,000) (450,000)
23-Sep-21 The Bank of New York Mellon Transfer out of Securities N/A (200,000) (200,000)
19-Oct-21 The Bank of New York Mellon Transfer out of Securities N/A (250,000) (250,000)
25-Oct-21 The Bank of New York Mellon Transfer out of Securities N/A (100,000) (100,000)
08-Nov-21 The Bank of New York Mellon Transfer out of Securities N/A (100,000) (100,000)
09-Nov-21 The Bank of New York Mellon Transfer out of Securities N/A (750,000) (750,000)
10-Nov-21 The Bank of New York Mellon Transfer out of Securities N/A (1,348,490) (1,348,490)
12-Nov-21 The Bank of New York Mellon Transfer out of Securities N/A (500,000) (500,000)
15-Nov-21 The Bank of New York Mellon Deposit of Securities N/A 54,180 54,180
15-Nov-21 The Bank of New York Mellon Transfer out of Securities N/A (8,236,480) (8,236,480)
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Print Name - Kevin Lockhart Capacity - Attorney - In - Fact Sign Here Date - 16 November 2021

Annexure C

This is Annexure C of 2 pages referred to in Form 604 Notice of Change of Interests of Substantial Holder given by The Bank of New York Mellon Corporation and its related bodies corporate Present relevant interests

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Holder of relevant interest Nature of relevant interest Class and number of
securities
The Bank of New York Remote Interest Held Under Deposit Agreement 263,792,979
Mellon ( BNYM ) ordinary shares
Relevant interest under section 608(1)(c) of the
Corporations Act 2001 (Cth) arising from BNYM having
the limited power to dispose of, or control the exercise
of a power to dispose of, securities deposited with or
held by BNYM (or its custodian or agent) in its capacity
as depositary administering an ADR program for
Immutep Limited (Company) under the Deposit
Agreement dated April 16, 2012 between the Company,
holders of American depositary receipts (ADRs) and
BNYM (Deposit Agreement). [See Note 1 below].
BNYMC Group (other than Relevant interest under section 608(3)(a) and/or section 263,792,979
BNYM) 608(3)(b) of the Corporations Act 2001 (Cth) being a ordinary shares
relevant interest held through a body corporate (namely
BNYM) in which the voting power of each other entity in
the BNYMC Group is above 20%, or that each other
entity in the BNYMC Group controls.
[See Note 1 and Note 2 below]
Pershing LLC Relevant interest under sections 608(1) of the 90 ordinary shares
Corporations Act 2001 (Cth) arising from Pershing LLC
being the registered owner of the securities.
BNYMC Group (other than Relevant interest under section 608(3)(a) and/or section 90 ordinary shares
Pershing LLC) 608(3)(b) of the Corporations Act 2001 (Cth) being a
relevant interest held through a body corporate (namely
Pershing LLC) in which the voting power of each other
entity in the BNYMC Group is above 20%, or that each
other entity in the BNYMC Group controls.
[See Note 2 below]
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NOTES :
Note 1 : Of the total of 263,793,069 securities in which the BNYMC Group has a relevant interest, BNYM has a
relevant interest in 263,792,979 securities as depositary for Immutep Limited ADR program
administered under the Deposit Agreement. BNYM's relevant interest in these securities arises as a result
of the Deposit Agreement containing rights for BNYM to dispose of securities held under the ADR
program in limited circumstances. Under the Deposit Agreement, ADR holders retain their rights to
dispose of those securities and to give voting instructions for the exercise of voting rights attached to the
securities. BNYMC Group's power to vote or dispose of these securities is qualified accordingly.
Note 2 : Each Group Entity is a direct or indirect wholly owned subsidiary of BNYMC, the ultimate parent
company. Other than BNYM in respect of 263,792,979 securities (of which BNYM's power to only
dispose of 263,792,979 securities is limited – see Note 1), and Pershing LLC in respect of 90 securities,
none of the BNYMC Group entities are entitled to be registered as holder of the securities and their power
to vote or dispose of the securities is qualified accordingly.
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print name Kevin Lockhart capacity Attorney-In-Fact
sign here date 16 November 2021____
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