IMMUTEP LIMITED — Director's Dealing 2025

Dec 4, 2025

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name of entity	IMMUTEP LIMITED (ASX: IMM)
ABN	90 009 237 889

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Dr Russell John Howard
Date of last notice	10 December 2024

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Indirect
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	Regulus Star Pty Ltd
Date of change	2 December 2025 – acquisition of Performance rights 4 December 2025 – Conversion of Performance rights to ordinary shares
No. of securities held prior to change	1. 1,417,977 Fully Paid Ordinary Shares 2. 100,000 Director Performance Rights
Class	1. Performance Rights (ASX: IMMAM) 2. Fully Paid Ordinary Shares (ASX: IMM)
Number acquired	1.) 1,573,646 Performance Rights 2.) 300,000 Fully Paid Ordinary Shares (ASX: IMM)
Number disposed	300,000 Performance Rights (ASX: IMMAM)

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	Nil for the issue of 300,000 shares. No amount is payable upon exercise of the 3rd tranche of Performance Rights which were approved by shareholders at the 2023 AGM and for the 1sttranche of Performance Rights which were approved by the shareholders at the 2025 AGM. Russell Howard is taking 50% of his fees for the period 1 December 2025 to 30 November 2028 in Performance Rights which will vest in accordance with the terms set out in the Notice of Annual General Meeting.
No. of securities held after change	1. 1,717,977 Fully Paid Ordinary Shares 2. 50,000 Performance Rights approved at 2023 AGM 3. 1,323,646 Performance Rights approved at 2025 AGM
Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buy- back	1,573,646 Performance Rights were acquired in accordance with shareholder approval obtained at the Annual General Meeting on 27 November 2025. 50,000 shares were issued upon vesting and exercising of 3rd tranche of Performance Rights out of the 178,356 additional Performance Rights which were issued in lieu of additional cash to compensate Dr Howard for his additional responsibilities as Chairman of the Company in accordance with the Shareholders approval obtained at the 2023 AGM. 250,000, shares were issued upon vesting and exercising of 1sttranche of Performance Rights out of the 1,573,646 Performance Rights were issued to Dr Howard in accordance with shareholder approval obtained at the 2025 AGM.

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract N/A

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011

Appendix 3Y Change of Director’s Interest Notice

Nature of interest	N/A
Name of registered holder (if issued securities)	N/A
Date of change	N/A
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed	N/A
Interest acquired	N/A
Interest disposed	N/A
Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation	N/A
Interest after change	N.A

Part 3 –[+] Closed period

Were the interests in the securities or contracts detailed above traded during a+closed period where prior written clearance was required?	No
If so, was prior written clearance provided to allow the trade to proceed during this period?	N/A
If prior written clearance was provided, on what date was this provided?	N/A

• See chapter 19 for defined terms.

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