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Immuron Ltd — Investor Presentation 2013
Nov 28, 2013
35121_rns_2013-11-28_794b60ee-a3c1-46fd-8f17-28a538ff4116.pdf
Investor Presentation
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ORAL IMMUNOTHERAPY USING BOVINE ANTIBODIES
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Forward-looking Statement
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Certain statements made in this presentation are forward-looking statements and are based on Immuron’s current expectations, estimates and projections. Words such as "anticipates," "expects," "intends," "plans," "believes," "seeks," "estimates," "guidance" and similar expressions are intended to identify forward-looking statements.
Although Immuron believes the forward-looking statements are based on reasonable assumptions, they are subject to certain risks and uncertainties, some of which are beyond Immuron’s control, including those risks or uncertainties inherent in the process of both developing and commercializing technology. As a result, actual results could materially differ from those expressed or forecasted in the forward-looking statements.
The forward-looking statements made in this presentation relate only to events as of the date on which the statements are made. Immuron will not undertake any obligation to release publicly any revisions or updates to these forward-looking statements to reflect events, circumstances or unanticipated events occurring after the date of this presentation except as required by law or by any appropriate regulatory authority.
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2013: THE ACHIEVEMENTS
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New Shareholders April rights issue: high networth investors who provide a lot of support
Travelan: continue commercialization
Fatty Liver / NASH
Direct-to-wholesale model in Australia, increase revenues Regulatory approval in Canada Regulatory progress in licensed territories Discussions in the US progressing Continue preparation for Phase IIb Clinical trial ASH trial cleared by FDA Industry (potential partner) interest
Clostridium Difficile and Very encouraging preventative result. Treatment studies other RD ongoing.
A number of promising applications, including for orphan conditions
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LOOKING AHEAD
What we are seeking to achieve
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Financial Strength
Improve balance sheet
Travelan: continue commercialization
US Travelan transaction
More licenses and more revenue
Fatty Liver / NASH Commence Phase IIb Clinical trial
Partner
Progress RD Progress to the clinic with another product
A number of promising applications, including for orphan conditions
We continue to nurture and benefit from strong partnerships with our research and development collaborators and with our commercial partners.
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TRAVELAN
The last 3 years
Takeda shed its License
License with Takeda
pharmacy sales force Termination
6,000
5,000
4,000
3,000
2,000
1,000
0
TRAVELAN
Jan-10 Feb-10 Mar-10 Apr-10 May-10 Jun-10 Jul-10 Aug-10 Sep-10 Oct-10 Nov-10 Dec-10 Jan-11 Feb-11 Mar-11 Apr-11 May-11 Jun-11 Jul-11 Aug-11 Sep-11 Oct-11 Nov-11 Dec-11 Jan-12 Feb-12 Mar-12 Apr-12 May-12 Jun-12 Jul-12 Aug-12 Sep-12 Oct-12 Nov-12 Dec-12 Jan-13 Feb-13 Mar-13
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TRAVELAN
Before July 2013
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TRAVELAN
Now (Australia)
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Immuron is commanding substantially higher margin
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TRAVELAN
Going Forward
Approved
In Discussion
In Discussion
Various
stages of<br>regulatory<br> process<br>Licensed In Discussion<br>
In Revenue `
Proceeding through
regulatory process
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IMM-124E for NASH
Mechanism of Action
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Oral Immunotherapy: An approach to treating autoimmune, infectious and inflammatory disease through the oral delivery of antibodies
There is continually growing scientific support for Immuron’s approach Immuron has the right product at the right time
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IMM-124E for NASH
Ready to go: Phase 2B trial
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Based on existing technology:
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Mature manufacturing process
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High Safety profile
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IND cleared by the FDA: Immuron set to commence clinical trials
Preparations under way
Investigators identified
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IMM-124E has been independently validated: selected as only 1 of 3 products to be studied for alcoholic steatohepatitis (ASH) under a fully funded NIH TREAT study
NASH remains a very large unmet medical need of significant interest to the medical profession and the pharmaceutical industry
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IMM-529 for Clostridium Difficile
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Clostridium difficile (C.diff): a bacteria normally found in people’s intestines
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Certain circumstances C.diff can multiply and its toxin causes illness such as diarrhoea & severe inflammation of the bowel
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C. diff infection accounts for:
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considerable increases in length of hospital stays
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more than US$3.2 billion in health care costs each year in the United States
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IMM-529 for Clostridium Difficile
Very encouraging results to date
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IMM-529 under collaboration with Monash University
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• All data owned by Immuron
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IMM-529 demonstrated positive pre-clinical results:
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Encouraging preventative data
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Treatment effect currently being investigated
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Proprietary vaccine given to cows being improved
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THE OPPORTUNITY
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Thank you
Contact Amos Meltzer – Chief Executive Officer 0437 587 680