GENETIC TECHNOLOGIES LIMITED — Major Shareholding Notification 2025

May 21, 2025

604 Page 1 of 2 15 July 2001

Form 604

Corporations Act 2001

Section 671B

Notice of change of interests of substantial holder

To Company Name/Scheme Genetic Technologies Limited ACN/ARSN 009 212 328

1. Details of substantial holder (1)

The Bank of New York Mellon Corporation (BNYMC) and each Group Name Entity listed in Annexure A (Group Entity),(together BNYMC Group)

ACN/ARSN (if applicable)

There was a change in the interests of the substantial holder on 14 / May / 2025 The previous notice was given to the company on 18 / July / 2024 The previous notice was dated 17 / July / 2024

2. Previous and present voting power

The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in when last required, and when now required, to give a substantial holding notice to the company or scheme, are as follows:

mpany or scheme, are as follows:
Class of securities (4)	Previous notice		Present notice
	Person’s votes	Voting power(5)	Person’s votes	Voting power(5)
Ordinary shares	103,900,271	71.45%	102,570,851*	7.68%**
			See Note 1in AnnexureC*** Updated**voting power% as aresult ofissuer’spublicnotice on 21May 2025announcingadditionalsharesissued as of14 May 2025,impactingthe totalsecuritieson issue.

3. Changes in relevant interests

Particulars of each change in, or change in the nature of, a relevant interest of the substantial holder or an associate in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows:

Person whoserelevant interestchanged	Nature of change (6)	Consideration given inrelation to change (7)	Class and numberof securitiesaffected	Person's votesaffected

604 Page 2 of 2 15 July 2001

4. Present relevant interests

Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows:

Registered holderof securities	Person entitled to beregistered as holder(8)	Nature of relevantinterest (6)	Class and numberof securities	Person's votes

5. Changes in association

The persons who have become associates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder in relation to voting interests in the company or scheme are as follows:

Name and ACN/ARSN (if applicable)	Nature of association
BNYMC and each GroupEntity	Each Group Entity is an associate of BNYMC pursuant tosection 12(2)(a) of the Corporations Act 2001 (Cth) as eachentity is directly or indirectly owned and controlled byBNYMC.

6. Addresses

The addresses of persons named in this form are as follows:

Name	Address
The Bank of New YorkMellon Corporation	240 Greenwich Street, New York, NY 10286 USA
Each Group Entity	240 Greenwich Street, New York, NY 10286 USA

Signature

print namesign here	Kevin LockhartcapacityAttorney-In-Fact
	date21/May/2025

Annexure A

This is Annexure A of 1 page referred to in Form 604 Notice of Change of Interests of Substantial Holder given by The Bank of New York Mellon Corporation and its related bodies corporate

The Bank of New York Mellon Corporation is the ultimate parent company of a corporate group comprised of a large number of operating and holding companies. Details of the entities directly owned and controlled by The Bank of New York Mellon Corporation are listed below.

• The Bank of New York Mellon

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Annexure B

This is Annexure B of 1 page referred to in Form 604 Notice of Change of Interests of Substantial Holder given by The Bank of New York Mellon Corporation and its related bodies corporate

Changes in relevant interest

Date of change	Person whose relevant interestchanged	Nature of Change	Consideration given inrelation to change	Class and number ofsecurities affected(Ordinary Shares)	Person's votesaffected
18-Jul-24	The Bank of New York Mellon	Transfer out of Securities	N/A	(330,000)	(330,000)
23-Jul-24	The Bank of New York Mellon	Transfer out of Securities	N/A	(210,000)	(210,000)
8-Oct-24	The Bank of New York Mellon	Transfer out of Securities	N/A	(168,420)	(168,420)
9-Oct-24	The Bank of New York Mellon	Transfer out of Securities	N/A	(300,000)	(300,000)
15-Oct-24	The Bank of New York Mellon	Transfer out of Securities	N/A	(321,000)	(321,000)

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Annexure C

This is Annexure C of 1 page referred to in Form 604 Notice of Change of Interests of Substantial Holder given by The Bank of New York Mellon Corporation and its related bodies corporate

Holder of relevant interest	Nature of relevant interest	Class and number ofsecurities
The Bank of New YorkMellon (BNYM)	Remote Interest Held Under Deposit AgreementRelevant interest under section 608(1)(c) of theCorporations Act 2001 (Cth) arising from BNYM havingthe limited power to dispose of, or control the exercise ofa power to dispose of, securities deposited with or heldby BNYM (or its custodian or agent) in its capacity asdepositary administering an ADR program for GeneticTechnologies Limited (Company) under the DepositAgreement dated January 14, 2002 between theCompany, holders of American depositary receipts(ADRs) and BNYM (Deposit Agreement).[*See Note 1 below].	102,570,851ordinary shares
BNYMC Group (other thanBNYM)	Relevant interest under section 608(3)(a) and/or section608(3)(b) of the Corporations Act 2001 (Cth) being arelevant interest held through a body corporate (namelyBNYM) in which the voting power of each other entity inthe BNYMC Group is above 20%, or that each otherentity in the BNYMC Group controls.[*See Note 1 and Note 2 below]	102,570,851ordinary shares
NOTES:Note 1: Of the total of102,570,851securities in which the BNYMC Group has a relevant interest, BNYM has arelevant interest in102,570,851securities as depositary for Genetic Technologies Limited ADR programadministered under the Deposit Agreement. BNYM's relevant interest in these securities arises as a result of theDeposit Agreement containing rights for BNYM to dispose of securities held under the ADR program in limitedcircumstances. Under the Deposit Agreement, ADR holders retain their rights to dispose of those securities andto give voting instructions for the exercise of voting rights attached to the securities. BNYMC Group's power tovote or dispose of these securities is qualified accordingly.Note 2: Each Group Entity is a direct or indirect wholly owned subsidiary of BNYMC, the ultimate parentcompany. Other than BNYM in respect of102,570,851**securities (of which BNYM's power to only dispose of102,570,851securities is limited – see Note 1), none of the BNYMC Group entities are entitled to be registered asholder of the securities and their power to vote or dispose of the securities is qualified accordingly.

print nameKevin Lockhart	capacity_ Attorney-In-Fact
sign here	date21/May/2025_