EXELIXIS, INC. — Director's Dealing 2010

May 20, 2010

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: EXELIXIS INC (EXEL)
CIK: 0000939767
Period of Report: 2010-05-19

Reporting Person: MARCHESI VINCENT T (Director)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2010-05-19	Option (right to buy)	$5.92	A	15000	Acquired	2020-05-18	Common Stock (15000)	Direct

Footnotes

F1: Options granted pursuant to Issuer's 2000 Non-Employee Directors' Stock Option Plan. The option is exercisable immediately, subject to repurchase provisions, and will vest monthly over the following year.