EXELIXIS, INC. — Director's Dealing 2026

Feb 20, 2026

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: EXELIXIS, INC. (EXEL)
CIK: 0000939767
Period of Report: 2026-02-17

Reporting Person: Smith Julie (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2026-02-17	Common Stock	M	42422	$18.19	Acquired	63012	Direct
2026-02-17	Common Stock	S	42422	$43.33	Disposed	20590	Direct
2026-02-18	Common Stock	M	44087	$19.39	Acquired	64677	Direct
2026-02-18	Common Stock	S	44087	$44.50	Disposed	20590	Direct
2026-02-18	Common Stock	M	20030	$21.69	Acquired	40620	Direct
2026-02-18	Common Stock	S	20030	$44.30	Disposed	20590	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2026-02-17	Option (right to buy)	$18.19	M	42422	Disposed	2029-05-25	Common Stock (42422)	Direct
2026-02-18	Option (right to buy)	$19.39	M	44087	Disposed	2030-05-31	Common Stock (44087)	Direct
2026-02-18	Option (right to buy)	$21.69	M	20030	Disposed	2031-05-30	Common Stock (20030)	Direct

Footnotes

F1: Includes 9,812 shares of Exelixis, Inc. common stock ("Common Stock") that will be issued to the Reporting Person upon vesting of restricted stock units ("RSUs"). Each RSU is the economic equivalent of one share of Common Stock.

F2: Represents the weighted average sales price. The shares were sold in multiple transactions at prices ranging from $44.30 to $44.44. Reporting Person undertakes to provide Exelixis, Inc., any security holder of Exelixis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote 2 to this Form 4.

F3: The option, representing the right to purchase a total of 42,422 shares of Common Stock, became fully exercisable on May 26, 2022.

F4: The option, representing the right to purchase a total of 44,087 shares of Common Stock, became fully exercisable on June 1, 2023.

F5: The option, representing the right to purchase a total of 20,030 shares of Common Stock, became fully exercisable on May 31, 2024.