CRYOSITE LIMITED — Board/Management Information 2008

Sep 21, 2008

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ASX RELEASE

Date: 22nd September 2008

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Subject: Appointment of Mr Graeme Moore as Executive Director

The Company wishes to advise the market of the appointment of Mr. Graeme Moore B.App.Sc (Biomed), MHA as an Executive Director.

Graeme Moore is currently the Quality and Regulatory Affairs Manager at Cryosite. Graeme joined Cryosite in July 2005 after a decade with the Australian Red Cross Blood Service. Graeme has over 20 years experience in biomedical science, manufacture of therapeutic goods, quality management and regulatory affairs. Graeme brings expertise in the regulation and manufacture of cellular therapies and process re-engineering to the company. Graeme is also responsible for ensuring that Cryosite’s systems retain the capacity to meet client’s needs in a constantly changing technological and regulatory environment.

Mr Moore’s Appendix 3x - Initial Director’s Interest Notice is attached

Bryan Dulhunty Company Secretary

9 Sirius Road Lane Cove NSW 2066 Australia phone +61 2 9420 1400 fax +61 2 9420 1414 email corporate@cryosite.com www.cryosite.com Cryosite Ltd ABN 86 090 919 476

Appendix 3X Initial Director’s Interest Notice

Rule 3.19A.1

Appendix 3X

Initial Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public. Introduced 30/9/2001.

Name of entity Cryosite Limited ABN 86 090 919 476

We (the entity) give ASX the following information under listing rule 3.19A.1 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Graeme Moore
Date of appointment	22 September 2008

Part 1 - Director’s relevant interests in securities of which the director is the registered holder

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Number & class of securities

Unlisted options issued under the employee option scheme

• 100,000 exercise price 20 cents, vest 30/10/2008

• 100,000 exercise price 30 cents, vest 30/10/2009

• 100,000 exercise price 40 cents, vest 30/10/2010

Expiry date of all options is 30 October 2012

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Appendix 3X Page 1

Appendix 3X Initial Director’s Interest Notice

Part 2 – Director’s relevant interests in securities of which the director is not the registered holder

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

	Name of holder & nature of interest Note: Provide details of the circumstances giving rise to the relevant interest. N/A	Number & class of Securities

Part 3 – Director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	N/A
Nature of interest
Name of registered holder (if issued securities)
No. and class of securities to which interest relates

Appendix 3X Page 2