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CONSTELLATION TECHNOLOGIES LIMITED Annual Report 2007

Oct 31, 2007

64712_rns_2007-10-31_e6ffc985-cdee-4fdc-aa1d-a76586a5c4db.pdf

Annual Report

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ANNUAL REPORT
07
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CONTENTS

Chairman’s Report 4
Managing Director’s Report 5
Board of Directors 10
Intellectual Property Rights 12
Financial Statements 13

3

AGENIX LIMITED ANNUAL REPORT 2007

CHAIRMAN’S REPORT

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“ Our company is in for exciting times in the next year.

Dear Shareholders,

The 2006/07 financial year has been a year of significant change.

The disposal of our human and animal health medical diagnostic businesses were finalised, save for some short term manufacturing and other business transfer tasks.

Our Brisbane, Australia-based wholly owned subsidiary, Agen Biomedical, during the year continued planning work for the commencement of a Phase II Pulmonary Embolism clinical trial. Indeed, that trial opened in Northern America for patient recruitment in September 2007. The expectation is that we will be ready to resume partnering discussions for ThromboView[®] during 2008.

Most notable during the year has been the establishment of a wholly owned subsidiary in China, Agenix Biopharmaceutical (Shanghai), and its acquisition of the businesses of two-related private companies in Shanghai in China: one a bio-pharmaceutical development company (SHRG) and the other a pharmaceutical manufacturing company (YSY).

The lead product, YouHeDing, an anti-hepatitis B virus drug, has successfully completed Phase III clinical trials and on 2 October 2007 we announced that we had received approval for the drug from the Chinese regulatory authority. We expect that YouHeDing will be deriving revenue in the second half of the 2007 calendar year.

As part of our acquisition in China we have acquired a pipeline of potential anti-viral drugs currently in pre-clinical development. The pharmaceutical manufacturing facility in Pudong (near Shanghai), China has the capacity to manufacture 150 million tablets per annum on a one-shift basis.

These acquisitions provide great promise and will form a platform for significant growth in the future.

The melding of different cultures in our company provides new challenges. However, enormous progress has been made on the integration of our Chinese operations into Agenix. Our Board has significant experience in conducting business in Asia generally, including China.

Changes to our Board reflect the strategic changes made this year. To that extent, I welcome Mr Jonathan Zhang, founder of SHRG, to our Board. I also welcome Mr Anthony Lee. Both Directors were appointed to the Board on 27 August 2007.

The finalisation of the disposal of our Animal Health and Human Health medical diagnostic businesses has continued to result in staff redundancies. On behalf of the Board, I wish all those people well for the future.

I offer thanks to all our staff for their efforts during the past year.

I thank shareholders for their continued support, particularly those contributing to capital raisings during the year, and assure you that our company is in for exciting times in the next year.

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Ravindran (“Ravi”) Govindan Chairman

4

AGENIX LIMITED ANNUAL REPORT 2007

MANAGING DIRECTOR’S REPORT

“ Implementing the transformation. Market launch approval in China. ThromboView[®] clinical trial underway in North America.

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CORPORATE STRATEGY

In my initial report to shareholders 12 months ago, I indicated that the Board had carried out a strategic review which had concluded that our strategy should be as follows:

  • RE-EVALUATE THE TIMING OF NEGOTIATIONS FOR A THROMBOVIEW[®] DEAL.

An attempt was being made to conclude a licensing deal for ThromboView[®] at too early a stage in its development. Further progress was required in clinical trials for the primary indication, pulmonary embolism, and in the development of a comprehensive data package suitable for a potential partner.

  • SELL OUR ANIMAL HEALTH AND HUMAN HEALTH DIAGNOSTIC TEST BUSINESSES.

Our Animal Health business was loss-making. We had low market share and attempts to grow revenue in the past had not been successful. In addition, contractual arrangements had been entered into which made it extremely unlikely that this business could become profitable for a number of years.

Our Human Health business had a very small market share and was positioned in a mature segment of the d-dimer diagnostic test market. Whilst this business was profitable, there had been no revenue growth for a number of years. Growth in this business could best be achieved by acquisition. However, the likely return to shareholders from such a strategy would have been less than from investment in other areas.

  • LEVERAGE OUR EXISTING SKILLS AND INFRASTRUCTURE IN MONOCLONAL ANTIBODY DEVELOPMENT TO DEVELOP A BROAD PIPELINE OF ANTIBODY-BASED THERAPEUTIC AND/OR IMAGING PRODUCTS.

The company had only one major development programme, the ThromboView[®] project. The best-performing life science companies have multiple programmes.

In addition, there had been a previous focus on imaging programmes only. This narrow approach was not supported by share market performance in Australia or overseas. As a result, the strategy has been broadened to consideration of both therapeutic and imaging programmes.

5

AGENIX LIMITED ANNUAL REPORT 2007

  • PLACE THE COMPANY ON A SOUND FINANCIAL FOOTING.

The confidence in the completion of a ThromboView[®] deal by December 2005 and the consequent receipt of an upfront milestone payment by that date had resulted in the company’s cash resources being limited. When it was realised that the completion of a ThromboView[®] deal by December 2005 was not only unlikely but also not appropriate, a small capital raising was essential. Therefore, a capital raising was announced in March 2006 and completed in May 2006.

The sale and leaseback of the company’s Brisbane properties was part of a sound financial management strategy. The disposals of Animal Health and Human Health assets were being carried out for strategic rather than financial reasons, but nonetheless generated additional cash.

Stringent cost saving regimes were also put in place. Nonetheless, operational initiatives resulted in revenue from the Human Health business increasing substantially in the second half year.

IMPLEMENTING OUR STRATEGY

As a result of this new strategy, we are in a period of transformation.

A number of announcements were made in 2006 demonstrating that we have been implementing this transformation of Agenix, as follows:

  • The announcement on 17 March 2006 of a share placement of $3.0 million at $0.22 per share.

  • The sale for $0.4 million of a property in Perth which had in past years supported research and development but more recently had been rented out as a non-core asset.

  • The announcement on 7 April 2006 of the assignment of intellectual property and granting of certain distribution rights for the loss-making Animal Health business to US company IDEXX Laboratories from which Agenix is expected to realise $10.0 million when all relevant operational transfer milestones are completed ($7.2 million has been received to date).

  • Sales initiatives, including above-budget sales of biological products, which will raise cash in excess of $2.0 million more than previously forecast.

  • Cost-cutting initiatives, including the announcement of redundancies.

  • The announcement on 20 June 2006 of completion of the interim analysis for the Phase II deep vein thrombosis clinical trial in the United States and Canada which supported the advance of the programme towards registration trials.

  • The announcement on 26 June 2006 of the sale and leaseback of our Brisbane, Australia properties, with a sale price of $5.15 million.

The transformation implementation process has continued this year, with the following activities:

  • The announcement on 25 July 2006 that our forecast result for the year ended 30 June 2006 was for a substantially reduced loss of ($3.7M) compared to ($13.6M) the previous year.

  • The announcement on 7 September 2006 of the appointment of world class people to our Scientific Advisory Board to support our new strategy.

  • The announcement on 26 October 2006 that a poster presentation on ThromboView had won the prestigious Best Poster Award at the CHEST 2006 Scientific Conference in Salt Lake City, Utah, USA.

  • The announcement on 16 November 2006 of the sale of the Human Health Laboratory-based products business to American Diagnostica Inc. of the USA for $3.5M.

  • The announcement on 14 February 2007 of the proposed acquisition of a private Chinese bio-pharmaceutical group, SHRG, for $16.5 million (this transaction settled on 5 June 2007).

  • The announcement on 5 March 2007 of the sale of the Human Health Point-Of-Care products business to BBI holdings of the UK for $3.9M.

  • The announcement on 28 March 2007 of a share placement to raise $3.5M.

  • The announcement on 16 May 2007 of the successful completion of a rights issue to shareholders to raise $6.7M.

  • The announcement on 6 August 2007 of the successful placement of shares to sophisticated investors and institutions to raise a further $6.7M.

  • The announcement on 2 October 2007 of the receipt of market approval in China for our anti-hepatitis B virus drug, YouHeDing.

6

AGENIX LIMITED ANNUAL REPORT 2007

THROMBOVIEW[®]

During the year the ThromboView[®] project achieved a number of important milestones, including:

  • The announcement on 10 August 2006 of the granting of patents for our ThromboView[®] technology in the United States and Singapore, with approval in other jurisdictions likely to follow. The patents granted expire on 26 June 2022.

  • The announcement on 31 August 2006 of a collaboration between our company and ANSTO (Australian Nuclear Science and Technology Organisation) for a research study into the development of a PET-labelled ThromboView[®] product. PET (Positron Emission Tomography) is an imaging technique which, has the potential to be used to create a product to image arterial-based clots.

  • The announcement on 13 February 2007 of the confirmation of strong efficacy results from the Phase II Deep Vein Thrombosis clinical trial.

  • Continued progress towards the design of a Phase II Pulmonary Embolism clinical trial to provide additional data to potential partners. This culminated in the commencement of the recruitment phase of the trial, with the imaging of the first patient being announced on 21 September 2007.

To date we have spent over $34.9 million on the ThromboView[®] project. We continue to have discussions regarding partnering arrangements with relevant parties. Data from the Phase II PE trial will provide the impetus to further discussions.

We will continue to place the project in a position which delivers maximum value to shareholders.

THROMBOVIEW[®] CUMULATIVE SPENDING

for the year ended 30 June

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$ ‘000
40,000
34,899
29,747
30.000
19,560
20,000
13,156
10,000 8070
2003 2004 2005 2006 2007
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MONOCLONAL ANTIBODY DEVELOPMENT PROGRAMMES

Agenix subsidiary, Agen Biomedical, has the skills and infrastructure which can be leveraged to other protein therapeutic/monoclonal antibody development programmes. Our development team is one of the few in Australia to have taken a monoclonal antibody all the way from bench research, through humanisation procedures, preclinical characterisation, first-in-man safety evaluation and on to late stage Phase II clinical studies.

We are actively seeking additional programmes. Areas of interest are in obtaining antibody-based programmes in the fields of oncology, inflammation, cardiovascular or other fields where there is a substantial unmet medical need.

Programmes which we are seeking to acquire are likely to range from pre-clinical development programmes to programmes which have commenced Phase I clinical trials. However, the primary focus is on programmes already in the clinic.

7

AGENIX LIMITED ANNUAL REPORT 2007

CASH AND “CASH BURN RATE”

At the date of this report we have $3.2 million in cash and no debt. We have a further $4.04 million in cash expected to be received from asset sale transactions and operational initiatives which have already occurred. Management and the Board will ensure that the company is adequately funded for its activities at any point in time.

NET LOSS AFTER TAX

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for the year ended 30 June
$ ‘000
(811)
(2,000)
(4,000) (3,721)
(4,773)
(6,000)
(8,000)
(10,000)
(12,000)
(13,616)
(14,000) (14,336)
(16,000)
2003 2004 2005 2006 2007
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EARNINGS BEFORE INTEREST, TAX, DEPRECIATION, AMORTISATION, RESEARCH & DEVELOPMENT for the year ended 30 June

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$ ‘000
8,497
10,000
5,587
5.000
854
-
(2,874)
(5,000)
(6,077)
(10,000)
2003 2004 2005 2006 2007
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OPERATIONAL PERFORMANCE

The operational result reflects the disposal of our medical diagnostic test businesses, the consequent winding down of manufacturing operations in Brisbane, the continued progress of our ThromboView[®] programme and the search for new opportunities.

8

AGENIX LIMITED ANNUAL REPORT 2007

SHARE PRICE PERFORMANCE

The graph below shows the performance of Agenix shares in the period from 3 July 2006 to 28 September 2007.

AGENIX SHARE PRICE

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from 3 July 2006 to 28 September 2007
$
0.35
0.30
0.25
0.20
0.15
0.10
0.05
0.00 JUL 06 AUG 06 SEP 06 OCT 06 NOV 06 DEC 06 JAN 07 FEB 07 MAR 07 APR 07 MAY 07 JUN 07 JUL 07 AUG 07 SEP 07
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In that period Agenix shares have increased 62.5%.

THE NEXT 12 MONTHS

Management and the Board of Directors will continue to advance operations in China – we have one product which will be deriving sales and we will introduce two new potential products into clinical trials. The ThromboView[®] project will continue to deliver data from the Phase II PE trial in North America.

We will continue to assess opportunities to utilise the company’s skill base and infrastructure in both Shanghai and Brisbane.

The company will consider all initiatives which will increase shareholder value.

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Neil Leggett CEO and Managing Director

9

AGENIX LIMITED ANNUAL REPORT 2007

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RAVINDRAN (“RAVI”) GOVINDAN – CHAIRMAN

Mr Ravindran Govindan read law at the University of Singapore and practiced as an advocate and solicitor in the supreme court of Singapore. As a serial entrepreneur with more than 27 years of experience as an investor and businessman, he co-founded diverse business interests in retail, biotech, medical device, IT, emerging technologies, real estate and manufacturing. Mr Govindan currently holds the position of Chairman of Magnus Energy Group Limited, an established oil and gas company listed on the Singapore Stock Exchange.

Mr Govindan was the co-founder and founding Chairman and Managing Director of MatrixView Limited, a company listed on the Australian Securities Exchange (ASX:MVU). Mr Govindan also provides strategic advice in the Asia Pacific Region for Latona Associates Inc, a private investment and financial advisory firm based in New York, USA. Mr Govindan was also Group President of the Fisher Scientific group of companies in the Asia Pacific Region.

Mr Govindan currently holds directorships in companies such as MedTech Global, a leading healthcare solutions provider in New Zealand and I NUOVI Cosmetics, which is the world’s first Asian based professional colour makeup line with a global presence.

DR ANDRE LAMOTTE – NON-EXECUTIVE DIRECTOR

Dr Lamotte is a Swiss entrepreneur, venture capitalist and experienced company director who has nurtured developing life sciences companies for nearly two decades. Dr Lamotte has a Bachelor of Science Degree from Ecole Centrale Paris, a Master of Science Degree and a Doctor of Science Degree from MIT (Massachusetts Institute of Technology) and a Master of Business Administration Degree from Harvard Business School.

Since 1988 Dr Lamotte has founded or co-founded 18 biotechnology and pharmaceutical companies, 7 medical technology companies and 2 medical service companies. Such companies include Arpida, Axovan, de CODE genetics, Neurex-Creagen, Cryocath, Diatide, ICAgen, Inspire Pharmaceuticals, Laser Vision, Acambis-Oravax, Paion, URRMA, and Vernalis. He also has a track-record of executing spin-offs from large pharmaceutical companies (such as Arpida from Roche, Paion from Schering AG and Targaceipt from RJR).

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BOARD OF DIRECTORS

10

AGENIX LIMITED ANNUAL REPORT 2007

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MR KARL SCHLOBOHM - NON - EXECUTIVE DIRECTOR

Mr Schlobohm is a Director of Prosperity Advisers, a fully integrated financial services firm. He spent seven years with Ernst & Young and more recently, was a Partner with mid tier accounting firm Grant Thornton with specialist expertise in business planning and facilitation.

Mr Schlobohm is Chairman of Australasian Retail Media Group Limited and Company Secretary of ASX listed Company Linc Energy Limited. He also acts as a Director and/or CFO for a number of private entities.

Mr Schlobohm has a Bachelor of Commerce Degree, Bachelor of Economics Degree, and a Masters of Taxation. He is a Chartered Accountant, Registered Tax Agent and a member of The Australian Institute of Company Directors.

MR JONATHAN ZHANG - CHIEF EXECUTIVE OFFICER CHINA AND DIRECTOR

Mr. Zhang who has a Bachelor of Science Degree from Fairleigh Dickinson University, New Jersey, USA is one of the originating founders, of Agenix’s Chinese organisations incorporating biopharmaceutical and GMP certified manufacturing operations. He is responsible for all new drug related research and development within the Chinese operations and is also Chief Executive Officer.

Mr Zhang has had previous extensive international pharmaceutical research and development experience in senior management roles for Sandoz, Ethical, Kendle, and Pfizer.

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Given Mr Schlobohm’s qualifications and experience, he has agreed to take responsibility to overview the financial affairs and financial reporting of the Company as well as acting as the Company Secretary.

MR NEIL LEGGETT – CEO AND MANAGING DIRECTOR

Appointed as CEO and Managing Director on 15 December 2005. Mr Leggett has been with Agenix since 1 May 2003, when he commenced as Chief Financial Officer and Company Secretary. He was appointed to the Board on 7 December 2004.

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MR ANTHONY LEE VUI HAN (LEE) –

NON - EXECUTIVE DIRECTOR

Mr Lee has in excess of 15 years international business experience and has been actively involved in business development/marketing, quality control and cost management.

Mr Lee has a Bachelor of Economics Degree with a Major in Banking & Finance.

Mr Lee is also involved in project management and is responsible for the management, business development, cost control, and growth of Malaysian companies such as UF Engineers Sdn BHD, a Company involved in major public utilities infrastructure such as highways, Onika Quarry Sdn BHD, a Company operating quarries in Tawau and Semporna and Leeka Holdings Sdn. BHD, a Company involved with palm oil plantations.

Mr Lee currently holds Directorships in the aforementioned companies.

Mr Leggett has a Bachelor of Commerce Degree and a Master of Business Administration Degree. He is a member of the Australian Institute of Company Directors, an Associate Fellow of the Australian Institute of Management, and a Fellow of both the Chartered Institute of Secretaries and Taxation Institute of Australia. Mr Leggett has been a company director for 18 years. Mr Leggett has broad experience as a senior executive and director covering a wide range of industries.

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11

AGENIX LIMITED ANNUAL REPORT 2007

INTELLECTUAL PROPERTY RIGHTS

PATENT FAMILY: THROMBOVIEW[®]

General Description: A de-immunised antibody or antibody fragment specific for an epitope on human D-dimer which recognises cross-linked fibrin but not fibrinogen.

Jurisdictions:

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COUNTRY PATENT NO. PRIORITY DATE ISSUE DATE EXPIRY DATE
Singapore 100592 26-Jun-01 28-Feb-06 26-Jun-22
United States 7087724 26-Jun-01 08-Aug-06 12-Jan-23
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PATENT FAMILY: ADEFOVIR DIPIVOXIL

General Description: Crystalized structure synthetic process and application.

Jurisdictions:

COUNTRY PATENT NO. PRIORITY DATE ISSUE DATE EXPIRY DATE
China 147148 04-Dec-02 17-Mar-04 03-Dec-22
China 147146 04-Dec-02 17-Mar-04 03-Dec-22
China 144533 04-Dec-02 25-Feb-04 03-Dec-22

12 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED ABN 58 009 213 754

FINANCIAL STATEMENTS

FOR THE YEAR ENDED 30 JUNE 2007

13

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED FINANCIAL STATEMENTS

For the year ended 30 June 2007

TABLE OF CONTENTS TABLE OF CONTENTS PAGE
Director’s Report 15
Independence Declaration 35
Corporate Governance Statement 36
Income Statement 41
Balance Sheet 42
Cash Flow Statement 43
Statement of Changes in Equity 44
Notes to the Consolidated Financial Statements 45
Note 1 Corporate Information 45
Note 2 Summary of Significant Accounting Policies 45
Note 3 Segment Reporting 53
Note 4 Revenues and Expenses 57
Note 5 Income Tax 59
Note 6 Discontinued Operations 60
Note 7 Loss per Share 62
Note 8 Dividends Paid and Proposed 62
Note 9 Cash and Cash Equivalents 63
Note 10 Trade and Other Receivables (Current) 64
Note 11 Inventories 64
Note 12 Receivables (Non-Current) 64
Note 13 Shares in Controlled Entities 64
Note 14 Property, Plant and Equipment 65
Note 15 Intangible Assets 66
Note 16 Share-Based Payment Plans 67
Note 17 Trade and Other Payables (Current) 69
Note 18 Derivative Financial Instruments 69
Note 19 Interest and Non-Interest Bearing Loans and Borrowings 70
Note 20 Provisions 71
Note 21 Contributed Equity and Reserves 72
Note 22 Financial Risk Management Objectives and Policies 74
Note 23 Financial Instruments 74
Note 24 Business Combinations 77
Note 25 Commitments and Contingencies 79
Note 26 Related Party Disclosure 80
Note 27 Events after Balance Sheet Date 82
Note 28 Auditor's Remuneration 82
Note 29 Director and Executive Disclosures 82
Directors’ Declaration 85
Independent Audit Report 86
Additional Information 88
Corporate Information 90

14 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report

Your Directors present their Report on the Company and its controlled entities for the financial year ended 30 June 2007.

DIRECTORS

The names and details of the Directors of the Company in office during the year and until the date of this Report are as follows. Directors were in office for the entire period unless otherwise stated.

Non-Executive Directors:

Mr Ravindran (“Ravi”) Govindan LLB (Hons) (Singapore)

Age 56

Non-Executive Chairman. Appointed 7 December 2004. Previously Executive Chairman appointed 13 June 2000.

Mr Ravindran Govindan read law at the University of Singapore and practiced as an advocate and solicitor in the supreme court of Singapore. As a serial entrepreneur with more than 27 years of experience as an investor and businessman, he has co-founded diverse business interests in retail, biotech, medical devices, IT and emerging technologies, real estate and manufacturing. Mr Govindan currently holds the position of Chairman of Magnus Energy Group Limited, an established oil and gas Company listed on the Singapore Stock Exchange.

Mr Govindan was the co-founder and founding Chairman and Managing Director of MatrixView Limited, a Company listed on the Australian Stock Exchange (ASX: MVU). He was appointed Director prior to MatrixView listing on the Australian Stock Exchange on 2 August 2004 until he resigned on 23 May 2006. Mr Govindan was also Group President of the Fisher Scientific group of companies in the Asia Pacific Region.

Mr Govindan currently holds Directorships in companies such as MedTech Global, a leading healthcare solutions provider in New Zealand and I NUOVI Cosmetics, which is the world’s first Asian based professional colour makeup line with a global presence. Mr Govindan also provides strategic advice in the Asia Pacific Region for Latona Associates Inc, a private investment and financial advisory firm based in New York, USA.

Mr Anthony Lee Vui Han (Lee) BEcon.

Age 38

Non-Executive Director. Appointed 27 August 2007.

Mr Lee has a Bachelor of Economics Degree with a Major in Banking & Finance.

Mr Lee has in excess of 15 years international business experience and has been actively involved in business development/marketing, quality control and cost management.

Mr Lee is also involved in project management and is responsible for the management, business development, cost control, and growth of Malaysian companies such as UF Engineers Sdn BHD, a Company involved in major public utilities infrastructure such as highways, Onika Quarry Sdn BHD, a Company operating quarries in Tawau and Semporna and Leeka Holdings Sdn. BHD, a Company involved with palm oil plantations.

Mr Lee currently holds Directorships in the aforementioned companies.

Dr Andre Lamotte BSc, M.S., Sc.D (MIT), MBA (Harvard)

Age 58

Non-Executive Director. Appointed 28 September 2005.

Dr Lamotte is a Switzerland-based entrepreneur, venture capitalist and experienced Company Director who has nurtured developing life sciences companies for nearly two decades.

Dr Lamotte has a Bachelor of Science Degree from Ecole Centrale Paris, a Master of Science Degree and a Doctor of Science Degree from MIT (Massachusetts Institute of Technology) and a Master of Business Administration Degree from Harvard Business School.

Since 1988 Dr Lamotte has founded or co-founded 18 biotechnology and pharmaceutical companies, 7 medical technology companies and 2 medical service companies. Such companies include Inspire Pharmaceuticals, Diatide, ICAgen, Oravax, Cryocath, Vernalis, Ontogeny, Neurex -Creagen, Axovan and Laser Vision. He also has a track record of executing spin-offs from large pharmaceutical companies (such as Arpida from Roche, Paion from Schering AG and Targaceipt from RJR).

15

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

Mr Karl Schlobohm B.Com, B.Ecom , M.Tax , CA, MAICD Chairman of the Audit Committee

Age 39

Non-Executive Director. Appointed 20 November 2006.

Mr Schlobohm has a Bachelor of Commerce Degree, Bachelor of Economics Degree, and a Masters of Taxation. He is a Chartered Accountant, Registered Tax Agent and a member of The Australian Institute of Company Directors.

Given Mr Schlobohm’s qualifications and experience, he has agreed to take responsibility to overview the financial affairs and financial reporting of the Company.

Mr Schlobohm is a Director of Prosperity Advisers, a fully integrated financial services firm. He spent seven years with Ernst & Young and more recently, was a Partner with mid tier accounting firm Grant Thornton with special expertise in business planning and facilitation. Mr Schlobohm has guided a number of start up enterprises through to commercial success.

Mr Schlobohm is Chairman of Australasian Retail Media Group Limited and Company Secretary of ASX listed Company Linc Energy Limited. He also acts as a Director and/or CFO for a number of private entities.

Executive Directors:

Mr Neil Leggett B.Com, MBA , CA, FCIS, FTIA, AFAIM, MAICD

Age 52

Chief Executive Officer and Managing Director. Appointed 15 December 2005. Previously Finance Director appointed 7 December 2004, Chief Financial Officer appointed 1 May 2003 (promoted out of this position 15 December 2005) and Company Secretary appointed 8 May 2003 (resigned as Company Secretary 15 December 2005).

Mr Leggett has a Bachelor of Commerce Degree and a Master of Business Administration Degree. He is a member of the Australian Institute of Company Directors, an Associate Fellow of the Australian Institute of Management, and a Fellow of both the Chartered Institute of Secretaries and Taxation Institute of Australia. Mr Leggett worked in chartered accountancy for 17 years and has 18 years of commercial experience.

Prior to this position he has held senior corporate financial positions including Chief Financial Officer and Company Secretarial roles at Orrcon Limited, A. Goninan and Sons Limited and Grow Force Australia Limited. He has been a chartered accountant for 27 years.

Mr Leggett was a Non-Executive Director of the ASX listed public Company MatrixView Limited. He was appointed 23 November 2004 and he resigned 18 August 2006.

Mr Zheng (Jonathan) Zhang B.Sc

Age 34

Chief Executive Officer of the recently acquired Chinese operations and appointed as a Director of the Company on 27 August 2007.

Mr Zhang has a Bachelor of Science Degree from Fairleigh Dickson University, New Jersey, USA.

Mr Zhang is one of the originating founders, of Agenix’ Chinese operations incorporating biopharmaceutical and GMP certified manufacturing operations and is responsible for all new drug related research and development within the Chinese operations.

Mr Zhang has also had previous extensive international pharmaceutical research and development experience in senior management roles for Sandoz, Ethical, Kendle, and Pfizer.

Directors not in office at date of report:

Mr Myles Davey BSc (UK), MA (UK)

Age 60

Non-Executive Director. Appointed 8 May 2003. Chairman of the Remuneration Committee. Resigned 20 November 2006.

Mr Davey has had an involvement in the medical diagnostics industry since 1972, working predominantly in marketing and general management, including with Abbott’s Laboratories.

Mr FF Wong (Wong Fong Fui) B Eng (Chem)

Age 63

Non-Executive Director. Appointed 11 August 2000. Resigned 12 December 2006.

Mr Wong is the Chairman and CEO of Boustead Singapore Ltd, a public company listed on the Singapore Stock Exchange. He also holds Directorships in many other companies in Singapore, Malaysia and Indonesia.

16 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

Directors not in office at date of report (continued):

Mr Gim-Choon Ang B.Arts

Age 58

Non-Executive Director. Appointed 12 December 2006. Member of the Audit Committee. Resigned 31 August 2007.

Mr Ang has a Bachelors Degree in Arts, majoring in Economics and Statistics from the University of Singapore.

Mr Ang has 25 years experience in the banking industry mostly within wholesale and merchant banking.

Company Secretary:

Mr Karl Schlobohm B.Com, B.Econ , M.Tax, CA, MAICD

Appointed 15 December 2005, as Joint Company Secretary. Appointed sole Company Secretary 13 July 2007.

INTERESTS IN THE SHARES AND OPTIONS OF THE COMPANY AND RELATED BODIES CORPORATE

As at the date of this Report the interests of the Directors in the shares and options of the Company were:

Ordinary
Shares
$0.30 Options
Expring
30/06/2011
Options
Expiring
20/07/2007
Options
Expiring
17/04/2009
Options
Expiring
21/07/09
Options
Expiring
21/07/2010
Options
Expiring
18/11/2010
Options
Expiring
15/12/2011
Options
Expiring
21/07/2012
Options
Expiring
17/04/2013
Options
Expiring
21/07/2013
R. Govindan
6,786,946
439,130
300,000
-
-
-
-
-
-
-
-
Dr A. Lamotte
-
-
-
-
-
-
-
-
-
-
-
K. Schlobohm
123,750
5,250
-
-
-
-
-
-
-
-
-
A. Lee
4,375,000
291,666
-
-
-
-
-
-
-
-
-
N. Leggett
2,000,000
238,333
-
-
175,000
250,000
1,250,000
4,000,000
500,000
- 500,000
J. Zhang
33,868,520
-
- 900,000
-
-
-
-
-
15,000,000

400,000
33,868,520 ordinary shares and 15,000,000 options held by J. Zhang were issued to W&Z Holdings Ltd, a company jointly owned by J. Zhang and R. Wang
Listed securities
Non-listed securities*
Listed securities Non-listed securities

LOSS PER SHARE

Cents

Basic and diluted earnings (loss) per share

(2.1)

DIVIDENDS PAID AND PROPOSED

No dividend has been paid or proposed by the Company in relation to the year ended 30 June 2007 (2006: $nil).

CORPORATE INFORMATION

Agenix Limited is a Company limited by shares that is incorporated and domiciled in Australia. Agenix is listed on the Australian Securities Exchange (Code: AGX).

Principal Activities

The principal activities of the Consolidated Entity during the financial year were:

  • Continued development of monoclonal antibody-based project ThromboView[®]

  • Continued sourcing of synergistic opportunities, the first of which culminated in the acquisition in China, covered in detail in Note 24 of this Report.

Employees

  • The Consolidated Entity employed 126 employees as at 30 June 2007 (2006: 57 employees). The increase is due to 72 employees from the Chinese acquisition effective 5 June 2007.

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OPERATIONAL AND FINANCIAL REVIEW

1. Operational Highlights

The main highlights of operations during the year were:

  • The announcement on 10 August 2006 of the granting of patents for our ThromboView[®] technology in the United States and Singapore, with approval in other jurisdictions likely to follow. The patents granted expire on 26 June 2022.

  • The announcement on 31 August 2006 of the collaboration with ANSTO (Australian Nuclear Science and Technology Organisation) for a research study into the development of PET-labelled ThromboView[®] product. PET (Positron Emission Tomography) is an imaging technique which has the potential to be used to create a product to image arterial-based clots.

  • Agenix appointed a world class Scientific Advisory Board. The five member team includes world-renowned experts in monoclonal antibody discovery and development.

  • The signing in November 2006, of an agreement with US based Company, American Diagnostica Inc (ADI), to sell the assets related to the laboratory-based range of Human Health d-dimer diagnostic products for $3.5 million.

  • The announcement on 26 October 2006 of the ThromboView[®] presentation at the CHEST 2006 Scientific Congress in Salt Lake City, Utah, US, winning the prestigious Best Poster Award.

  • The announcement on 1 February 2007 that the agreement with ADI had gone unconditional and settlement would occur on 28 February 2007.

  • The announcement on 13 February 2007 that the final ThromboView[®] Phase II DVT Report confirmed the product’s strong efficacy, which had been reported at the interim analysis.

  • The announcement on 14 February 2007 of the acquisition of the business interests of a Chinese bio-pharmaceutical operation which has a pipeline of products in development, for RMB100 million (A$16.5 million), made up of RMB49 million (A$8.1 million) in cash and up to RMB51 million (A$8.4 million) in the form of Agenix shares over the next two years if performance milestones are achieved.

  • The announcement on 5 March 2007 of the signing of an agreement to sell the assets related to the Simplify and SimpliRED point-of-care range of Human Health D-dimer diagnostic products to BBI Holdings Plc (BBI) of Cardiff, UK for $3.9 million.

  • The announcement on 28 March 2007 of a share placement which raised $3.1 million at $0.11 per share net of costs.

  • The announcement on 16 April 2007 of a 1:4 rights issue at $0.11 per share which raised $6.17 million net of costs.

  • Extraordinary General Meeting of shareholders on 17 April 2007, where shareholders overwhelmingly voted in favour of the SHRG acquisition.

  • The announcement on 6 June 2007 advising of the settlement of the SHRG acquisition.

2. Financial Overview

(a) Agenix Bio-Pharmaceutical (Shanghai) Co., Ltd Acquisition

On 14 February 2007 Agenix announced the agreement for the acquisition of two related private companies established in the People’s Republic of China (PRC). Agenix, through its wholly owned subsidiary (WOFE) Agenix Bio-Pharmaceutical (Shanghai) Co., Ltd, acquired all of the business assets and liabilities of Shanghai Rui Guang Bio-Pharma Development Co., Limited (SHRG), together with an option to acquire 100% of the shares of SHRG (for no further consideration). At the date of acquisition SHRG had a 55% shareholding interest in a Shanghai based pesticide Company, which was not included in the acquisition. SHRG is engaged in the development of a pipeline of anti-viral drugs. Under the agreement, Agenix also acquired 96% of the shares in Shanghai Yi Sheng Yuan Pharmaceuticals Co., Limited (YSY), which will manufacture drugs developed by SHRG and other parties.

The most developed product in SHRG’s product pipeline is an anti-hepatitis B virus drug called YouHeDing, which is expected to receive approval for market from the State Food & Drug Administration of the People’s Republic of China in the last quarter of the 2007 calendar year.

SHRG also has further pre-clinical products that are in the process of being developed within its product pipeline, including a next generation anti-hepatitis B virus drug which will be complementary to YouHeDing in the market, as well as separate drugs showing efficacy against HIV, colon cancer and liver cancer.

More information about this acquisition can be found in Note 24 of this Report – “Business Combinations”.

(b) Discontinued / Continuing Operations

In line with its previously announced strategic direction, Agenix has sold its non-core Animal Health and Human Health businesses. Agenix will continue to develop a broad pipeline of monoclonal antibody-based products, of which ThromboView[®] is the first. The non-core businesses are described as “Discontinued Operations” under accounting standards. At the time of this Report, Agenix is still manufacturing product under a supply-only arrangement for the purchaser of the Human Health business. That arrangement is anticipated to end on 28 February 2008. “Continuing Operations” currently encompasses the Company’s ThromboView[®] project, its interest in its Chinese drug development and pharmaceutical manufacturing operations, and its Australian corporate overheads.

18

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AGENIX LIMITED Directors’ Report continued

2. Financial Overview (continued)

(c) Financial result

The loss after tax of ($4,778,000) was higher than the prior year’s loss of ($3,721,000), although considerably lower than the losses in 2005 and 2004 attributable to members of Agenix.

The major contributors to the loss this year were:

Gross profit from continuing operations
Occupancy and administrative expenses
Operating profit from discontinued operations
Profit on the disposal of discontinued operations
Finance costs
Other items
Total loss
Attributable to minority interest
Attributable to members of Agenix
Research and development expenses - ThromboView ®
$ 000
1,048
(5,318)
(5,304)
5,667
1,256
(1,378)
(4,029)
(749)
(4,778)
(5)
(4,773)

(d) Loss per share

The basic and diluted loss per share increased 5% to (2.1) cents per share compared to (2.0) cents per share in the prior period.

(e) Revenue

Revenue 1
Sales
Agen - Human Health
Agen - Animal Health
Molecular biology
Consolidated results Consolidated results
30-Jun
2007
$ 000
30-Jun
2006

$ 000
8,506
171
95
12,468
4,131

248
8,772 16,847
Agen-Revenue from royalties and licences
Clinical trial revenue
Contract development revenue
Agen-Rental revenue
Finance revenue
-
194
47
-
762

448
234

78

44
273
Total Revenue 9,775 17,924
Note:

1 Revenue for Agen will be disclosed under discontinued operations for statutory purposes.

  • Total revenue is disclosed in the attached accounts as:
Continuing operations

Discontinuing operations

2007
$ 000
1,098
8,677
9,775
2006
$ 000
833
17,091
17,924
2006
  • Agen sales revenue declined due to the disposal of the non core Animal Health and Human Health businesses.

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AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

2. Financial Overview (continued)

(f) Expenditure

  • (i) Research and Development
Research and development
Continuing operations
ThromboView ®project
Other
Consolidated results Consolidated results
30-Jun
2007
$ 000
30-Jun
2006
$ 000
5,152
152
10,187
211
10,398
521
10,919
Discontinued operations:
Animal and Human Health
5,304
-
Total research and development 5,304
  • ThromboView[®] expenditure decreased 49.4% over last year, due to lower clinical trial and product manufacturing costs.

  • The first patient for the Phase II PE study was recruited on 21 September 2007.

(ii) Salaries & Wages

Employee expenses
Continuing operations
Salaries and wages (including on costs)
Share based Payments
Corporate restructure - redundancies
Executive termination payments
Write-back of executive share-basedpayments expense
Consolidated results Consolidated results
30-Jun
2007
$ 000
30-Jun
2006
$ 000
2,229
230
62
78
-
2,330
469
38
662
(215)
2,599 3,284
Discontinued
Salaries and wages (including on costs)
Share based payments expense / (write-back)
Corporate restructure - redundancies
1,946
97
306
3,689
(186)
272
2,349 3,775
Total employee expenses 4,948 7,059
  • Employee numbers on 30 June 2007 were 126 compared to 57 as at 30 June 2006. The increase is due to 72 employees from the Chinese acquisition effective 5 June 2007.

  • Agenix Group employee expenses decreased by 30% in the year ended 30 June 2007 compared to the year ended 30 June 2006.

(g) Distribution to shareholders

Dividends

The Company will not be paying a dividend in relation to the current period nor did it pay a dividend in the previous period. The Company does not anticipate that it will be paying a dividend in the year ended 30 June 2008.

(h) Balance Sheet

Total equity at 30 June 2007 was $19,752,000, which was an increase of $5,541,000 over the prior year due to the receipt of new share capital of $9,278,000 (net of costs), and an increase in the share option reserve of $1,126,000 which was offset against the operating loss incurred this financial year of $4,778,000.

Assets exceed Liabilities at 30 June 2007 by a ratio of 3.48 : 1 (2006: 2.5 : 1).

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2. Financial Overview (continued)

(i) Share issue

(i) Capital Raising

Share Placement Announced 28 March 2007

On 28 March 2007 Agenix announced the successful placement to institutional and sophisticated investors in Australia and Asia of 31,889,000 shares at $0.11 per share to raise $3.1 million (net of costs).

Rights Issue Announced 16 April 2007 (1:4 basis)

On 16 April 2007 Agenix announced a fully underwritten 1 for 4 rights issue to raise $6.17 million (net of costs) through the issue of 61,121,205 new shares and 20,373,735 attaching options. The issue offered 1 new share for every 4 shares held, at a subscription price of $0.11 per share, together with one attached new listed option exercisable at $0.30 for every 3 new shares subscribed for. The attached options can be exercised at any time up until 30 June 2011.

(ii) Shares and Options Issued in Relation to the SHRG Acquisition

SHRG Completion Shares and Options

Following the settlement of the SHRG acquisition, and in accordance with the Acquisition Agreement, Agenix issued the following securities on 6 June 2007:

  • 33,868,520 shares at $0.16 each to the Chinese vendor shareholders, fully financed by a non-cash, non-recourse loan from Agenix at 8% interest per annum. The shares are subject to the following escrow conditions: 50% to 17 April 2008, 30% to 17 April 2009 and 20% to 17 April 2010; and

  • 15 million options over unissued Agenix shares. The options are in five (5) tranches of 3 million, vest on 17 April 2010, expire on 17 April 2013 and have exercise prices ranging from $0.30 for the first tranche and increasing in $0.10 increments to $0.70 for the final tranche.

SHRG Milestone Options

Upon achieving certain performance criteria, milestone options approved for issue under the SHRG acquisition agreement, entitle the SHRG vendor shareholders to be issued Agenix shares up to a total value of RMB 51 million (A$7.6million). Refer to Note 21 and Note 24.

(iii) Employee Options

During the financial year, no employees or consultants exercised their options to acquire fully paid ordinary shares in Agenix Limited. Since the end of the financial year, no options have been exercised.

Issue of Employee Options under Employee Option Plan

The Company issues options to employees under the employee option plan on 21 July each year, subject to confirmation by the Directors. The exercise price under the plan rules is to be the average closing price of Agenix Limited fully paid ordinary shares for the 20 trading days prior to each 21 July, or as otherwise determined by the Directors. Refer to note 16 for details on options granted during the year and outstanding at 30[th] June 2007. Subsequent to the end of the year, the following options were granted:

  • (a) Effective 21 July 2007 2,600,000 options were issued to employees pursuant to the Company’s annual option grant policy. These options have a vesting period of 2 years, an exercise price of $0.24 and expire on 21[st] July 2013. As part of remuneration for additional duties performed for the Company, the Company intends to issue 125,000 options to Mr Karl Schlobohm (a Nonexecutive Director) on the same terms and conditions as outlined, but subject to shareholder approval.

  • (b) Also effective 21 July 2007 the Board of Directors issued 2,880,000 “short-term” options to employees as a “one-off’ exercise to provide incentive to Company management due to the significant difference between the historical option prices and the recent share price performance. These options were issued with an exercise price of $0.24, vest immediately, and expire after 24 months. The Company also intends to issue 3,120,000 options to Mr Neil Leggett (CEO and Managing Director) on the same terms and conditions as outlined, but subject to shareholder approval.

21

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AGENIX LIMITED Directors’ Report continued

2. Financial Overview (continued)

(iv) Lapsing of Employee Options

As a result of employees ceasing employment with Agenix 2,152,500 employee options were forfeited during the year.

(j) Statement of Cash Flows

(i) Cash on hand

Cash on hand
$ 000
Cash on hand 30 June 2006 8,743
Outflow relatingto Thromboview ® (4,454)
(4,454)
Other operatingcashflows (6,126)
(10,580)
Capital expenditure (27)
Payment for the Agenix (Shanghai) Bio-pharm acquistion (9,009)
Proceeds from sale of property, plant and equipment 5,563
Proceeds from the sale of discontinued operations (net of costs of sale) 4,649
Proceeds from sale of Industrial Biosystems PtyLtd 165
1,341
Repayment of borrowings (5,000)
Proceeds from issue of shares from capital raisings (net of costs) 9,278
Loans to other entities -
Cash on hand 30 June 2007 3,782

RISK MANAGEMENT

A structured approach is taken towards risk management. These risks include foreign currency, credit, liquidity, compliance and operational risk. Management is responsible for implementing risk management strategies and reporting back to the Board or Audit Committee, as appropriate.

The Managing Director and Finance Director have provided a declaration to the Board that the Company’s Financial Statements and Reports that:

  • 1) The Company’s financial records have been properly maintained for the relevant financial period.

  • 2) The Company’s financial reports are complete, present and true and fair view in all material respects.

  • 3) The above statements are based on a sound system of risk management and internal compliance and control, which in all material respects, complies with the policies of the Audit Committee.

The Company, for all of its operating entities, has centralised financial control and policy. This ensures consistency of application throughout the Group. For the purpose of ensuring financial integrity from our Chinese operations, the Company has engaged professional Asian-based advisors.

Foreign currency risk

The Group has transactional currency exposures. Such exposures arise from sales and purchases in currencies other than the Group’s measurement currency. The Group manages this through the use of US dollar bank accounts as well as forward exchange contracts designed to hedge specified amounts for foreign currencies in the future at stipulated exchange rates. The objective in entering into the forward exchange contracts is to protect the Group against unfavourable exchange rate movements for both contracted and anticipated future sales and purchases undertaken in foreign currencies.

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AGENIX LIMITED Directors’ Report continued

2. Financial Overview (continued)

Credit risk exposure

The Group trades only with recognised, creditworthy third parties. It is the Group’s policy that all customers who wish to trade on credit terms are subject to credit verification procedures. Since the Group trades with recognised third parties, there is no requirement for collateral.

Credit risk in trade receivables is managed in the following ways:

  • payment terms are 30 days for domestic customers and 60 days for international customers; and

  • a risk assessment process is used for customers with balances over $25,000.

Liquidity risk

The Group manages liquidity risk by maintaining adequate reserves, banking facilities and reserve borrowing facilities by continuously monitoring forecast and actual cash flows and matching the maturity profile of financial assets and liabilities.

Operational risk

Operational risk is the risk of non-compliance with internal guidelines and policies which may result in a loss in either a financial or reputational sense.

The Group has stringent Quality Assurance controls in its operations and has a regular management review process to ensure compliance. Deviation from accepted parameters are reported to the Board.

STATEMENT OF COMPLIANCE

This Report is based on the guidelines in The Group of 100 Incorporated publication Guide to the Review of Operations and Financial Condition .

SIGNIFICANT CHANGES IN THE STATE OF AFFAIRS

Establishment of Operations in China

On 5 June 2007, Agenix established operations in China, via the acquisition of two related private companies. Agenix, through its wholly owned subsidiary Agenix Bio-Pharmaceutical (Shanghai) Co. Ltd, acquired all of the business assets and liabilities of Shanghai Rui Guang Bio-Pharma Development Co. Limited (SHRG), together with an option to acquire 100% of the shares of SHRG (for no further consideration). At the date of acquisition SHRG held a 55% shareholding interest in a Shanghai based pesticide Company, which was not included in the acquisition. SHRG is engaged in the development of a pipeline of anti-viral drugs. Under the agreement, Agenix also acquired 96% of the shares in Shanghai Yi Sheng Yuan Pharmaceuticals Co. Limited (YSY), which will manufacture drugs developed by SHRG and other parties. Refer to note 24 for further details.

Discontinuance of Human Health business

The Company successfully disposed of its Human Health business during the year. The disposal was in line with the Company’s long-term focus and strategy, and which was noted in the 30 June 2006 Annual Report as a business held for sale. Refer to note 6 for further details.

SIGNIFICANT EVENTS AFTER BALANCE DATE

Under announcements made on the 6[th] and the 16[th] of August 2007, the Company raised $7,150,000 (before costs) for the issue of 44,687,500 shares at $0.16 each. This capital raising was undertaken in line with shareholder approval at a meeting of shareholders convened on 17 April 2007, and predominantly provided working capital for the drug development pipeline of the Company’s Chinese operations.

FUTURE FINANCIAL PROSPECTS

Following its previously announced strategy, the Company has successfully divested itself of its non-core businesses and assets, allowing it to focus on:

(i) the further development of its existing ThromboView[®] technology, and (ii) the further expansion of its product development pipeline, including via acquisition.

The Company continues to be involved in discussions with a number of parties with regard to a partnering deal for the further development and ultimate commercialisation of ThromboView[®] . Critical to this on-going process is the conduct of Phase II Pulmonary Embolism trials in Northern America. At the time of this Report, the Company is in the midst of conducting this important trial across seven (7) sites in the USA and Canada.

23

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AGENIX LIMITED Directors’ Report continued

2. Financial Overview (continued)

FUTURE FINANCIAL PROSPECTS (continued)

The Company expects SHRG to receive approval for the sale of its first drug, YouHeDing, within the Chinese domestic market in the fourth quarter of 2007. This important step is expected to herald the commencement of significant revenues from sales of the anti-hepatitis B drug. Importantly, part of the cash flows expected to be generated from YouHeDing will be utilised in the further development of the SHRG drug development pipeline, which includes a next generation anti-hepatitis B drug which will be complimentary to YouHeDing in the Chinese market, and drugs showing efficacy against HIV, colon cancer, and liver cancer.

ENVIRONMENTAL REGULATION AND PERFORMANCE

The Consolidated Entity holds any necessary licences issued by the relevant environmental protection authorities. These licences specify limits and regulate the management of discharges to the air and storm water run-off associated with the production processes and storage of any hazardous materials.

There have been no significant known breaches of the Consolidated Entity’s licence conditions.

SHARE OPTIONS

Unissued ordinary shares

At the date of this Report, there were the following options which could be exercised into ordinary shares under the employee option plan:

(b) Options held at the end of the reporting period:

The following table summarises information about options held by employees as at 30 June 2007:

WAEP
Number of options Grant date Vesting date Expiry date $
1,014,200 20 July 2001 19 July 2003 20 July 2007 0.3228
457,500 14 March 2003 25 July 2004 25 July 2008 0.3328
842,500 6 October 2003 21 July 2005 21 July 2009 0.4128
945,750 21 September 2004 21 July 2006 21 July 2010 0.6728
1,250,000 18 November 2004 18 November 2006 18 November 2010 0.5428
1,328,250 31 August 2005 21 July 2007 21 July 2011 0.2928
1,470,000 31 August 2006 21 July 2008 21 July 2012 0.2200
500,000 21 November 2006 21 July 2008 21 July 2012 0.2500
3,000,000 21 November 2006 15 December 2007 15 December 2011 0.5300
1,000,000 21 November 2006 15 December 2008 15 December 2011 0.5300
3,000,000 6 June 2007 18 April 2010 17 April 2013 0.3000
3,000,000 6 June 2007 18 April 2010 17 April 2013 0.4000
3,000,000 6 June 2007 18 April 2010 17 April 2013 0.5000
3,000,000 6 June 2007 18 April 2010 17 April 2013 0.6000
3,000,000 6 June 2007 18 April 2010 17 April 2013 0.7000
26,808,200

^ Weighted average exercise price (WAEP)

Effective 21 July 2007 2,600,000 unlisted options were granted to employees under the Employee Option Plan with an exercise price of $0.24, expiring 21 July 2013. A further 2,880,000 unlisted options were granted to key executives vesting immediately with an exercise price of $0.24, expiring on 21 July 2009.

Subject to shareholder approval, the Directors have approved the issuance of 3,120,000 options to Neil Leggett and 125,000 options to Karl Schlobohm with an exercise price of $0.24, vesting immediately and expiring in two years.

At 30 June 2007, there were the following unissued options which could be exercised into ordinary shares, which have been granted to external consultants of the Company:

WAEP
Number of options Grant date Vesting date Expiry date $
250,000 27 December 2002 22 September 2004 22 September 2009 0.4000
200,000 1 January 2006 1 January 2006 1 January 2012 0.4000
450,000

Options cannot be transferred and are not quoted on the Australian Securities Exchange. Option holders do not participate in any share issue or interest issue of the Company or any other body corporate. They have no voting powers.

Shares issued as a result of the exercise of options

During the financial year, no employees or consultants exercised their options to acquire fully paid ordinary shares in Agenix Limited. Since the end of the financial year, no options have been exercised.

24

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

INDEMNIFICATION AND INSURANCE FOR DIRECTORS AND OFFICERS

During the year, the Consolidated Entity has paid premiums in respect of a contract insuring all of the Directors and executive officers of the Consolidated Entity against a liability incurred in their role as Directors and officers of the Consolidated Entity, except where:

  • (a) The liability arises out of conduct involving a wilful breach of duty; or

  • (b) There has been a contravention of Sections 182 or 183 of the Corporations Act 2001.

The Company paid a premium in respect of a contract insuring Directors, secretaries and executive officers in respect of certain liabilities. The insurance contract contains a confidentiality condition, which prohibits disclosure of the nature of the liabilities insured or the premium paid.

REMUNERATION REPORT (AUDITED)

This Remuneration Report outlines the remuneration arrangements in place for Directors and executives of Agenix Limited (the Company).

Remuneration philosophy

The performance of the Company depends upon the quality of its Directors, executives and staff. To prosper, the Company must attract, motivate and retain highly-skilled Directors and executives.

To this end, the Company embodies the following principles in its remuneration framework:

  • Provide competitive rewards to attract high calibre executives

  • Link executive rewards to shareholder value

  • Allocate a significant portion of executive remuneration as ‘at risk’, dependent upon meeting pre-determined performance benchmarks

  • Establish appropriate, demanding performance hurdles in relation to variable executive remuneration.

Remuneration Committee

The Remuneration Committee of the Board of Directors of the Company is responsible for determining and reviewing compensation arrangements for the Directors, the Chief Executive Officer (CEO) and the senior management team.

The Remuneration Committee assesses the appropriateness of the nature and amount of remuneration of Directors and senior managers on a periodic basis by reference to relevant employment market conditions with the overall objective of ensuring maximum stakeholder benefit from the retention of a high quality Board and executive team.

Remuneration structure

In accordance with best practice corporate governance, the structure of non-executive Director and senior manager remuneration is separate and distinct.

Non-Executive Director remuneration

The Board seeks to set aggregate remuneration at a level which provides the Company with the ability to attract and retain Directors of the highest calibre, whilst incurring a cost which is acceptable to shareholders.

Non-Executive Director remuneration is determined within the aggregate Directors fee pool, which is periodically recommended for approval by shareholders. The latest determination was at an Extraordinary General Meeting held on 17 April 2007 when shareholders approved an aggregate remuneration of $500,000 per annum. The actual amount paid during the financial year ended 30 June 2007 was $328,043 (2006: $319,273).

Each Director receives a fee for being a Director of the Company. No additional fees are paid for Board committee membership. Should a Director be requested by the Chairman to undertake review work additional to normal Board and Board committee work, the Director receives additional fees based on commercial hourly rates. However the additional fees will not result in the aggregate amount of Directors’ fees approved by shareholders being exceeded.

Non-Executive Directors have long been encouraged by the Board to hold shares in the Company (purchased by the Director on market). Shareholdings of Directors are disclosed within this Report.

The remuneration of Non-Executive Directors for the period ending 30 June 2007 is detailed in Table 1 of this Report.

25

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REMUNERATION REPORT (continued)

Senior Manager and Executive Director remuneration

The Company aims to reward executives with a level and mix of remuneration commensurate with their position and responsibilities within the Company and so as to:

  • reward executives for Company, business unit and individual performance against targets set by reference to appropriate benchmarks;

  • align the interests of executives with those of shareholders;

  • link reward with the strategic goals and performance of the Company; and

  • ensure total remuneration is competitive by market standards.

In determining the level and make-up of executive remuneration, the Remuneration Committee benchmarks remuneration packages with comparable organisations.

It is the Remuneration Committee’s policy that employment contracts are entered into for all senior executives. Details of the contracts for the Chief Executive Officer (“CEO”), the Director Research and Product Development, the Director Clinical and Commercial Programs and the Operations Manager are provided within this Report.

Remuneration consists of the following key elements:

  • Fixed Remuneration

  • Variable Remuneration - Short Term Incentive (‘STI’); and

  • Long Term Incentive (‘LTI’).

The proportion of fixed remuneration and variable remuneration (potential short term and long term incentives) is established for each senior executive by the Remuneration Committee and for other employees by the CEO. Table 2 of this Remuneration Report details the fixed and variable components percentage of the senior executives of the Company.

Fixed remuneration

The level of fixed remuneration is set so as to provide a base level of remuneration, which is both appropriate to the position and is competitive in the market.

Fixed remuneration is reviewed annually by the Remuneration Committee and the process consists of a review of Companywide, business unit and individual performance, relevant comparative remuneration in the market and internal and, where appropriate, external advice on policies and practices.

Senior executives are given the opportunity to receive their fixed (primary) remuneration in a variety of forms including cash and fringe benefits such as motor vehicles and additional superannuation, which is provided by salary sacrifice. It is intended that the manner of payment chosen will be optimal for the recipient without creating undue cost for the Company.

The fixed remuneration component of the senior executives is detailed in Table 2 of this Remuneration Report.

Variable remuneration – Short Term Incentive (STI)

The objective of the STI program is to link the achievement of the Company’s operational targets with the remuneration received by the executives charged with meeting those targets. The total potential STI available is set at a level so as to provide sufficient incentive to the senior manager to achieve the operational targets and such that the cost to the Company is reasonable in the circumstances.

Actual STI payments granted to each senior manager depend on the extent to which specific operating targets, set at the beginning of the financial year are met. The operational targets consist of a number of Key Performance Indicators (KPIs) covering both financial and nonfinancial measures of performance. Typically included are measures such as contribution of net profit after tax, customer service and product management.

The aggregate of annual STI payments available for senior executives within the Company is subject to the approval of the Remuneration Committee. Payments made are usually delivered as a cash bonus or as a superannuation contribution.

26 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

REMUNERATION REPORT (continued)

Senior Manager and Executive Director remuneration (continued)

Variable pay – Long Term Incentive (LTI)

The LTI plan aims to reward executives in a manner, which aligns this element of remuneration with the creation of shareholder wealth.

As such LTI grants are only made to executives who are able to influence the generation of shareholder wealth and thus have a direct impact on the Company’s performance against the relevant long-term performance hurdle.

LTI grants to executives are delivered in the form of options.

All options issued under the employee option plan, including executive options, have a two year vesting period. If an executive ceases employment with the Company prior to the options vesting, then those options are forfeited. Vested options are forfeited if they are not exercised within one month upon an executive ceasing employment with the Company, or six months in special circumstances as deemed appropriate by Board of Directors.

Remuneration, Company performance and shareholder wealth

The development of remuneration policies and structures are considered in relation to the effect on Company performance and shareholder wealth. They are designed by the Board to align Director and executive behaviours with improving Company performance and ultimately, shareholder wealth.

The generally improving trend in the Company’s financial performance over the recent past reflects the rationalisation and refocussing of the Company’s direction. The Directors expect this trend to continue into the future, with the Company moving into profits by virtue of its activities in China. In addition, while the Company’s share price has improved during the financial year it remains below the average price for the last few years. The table below sets out the Company’s share price at the end of each of the last five financial years, together with the Earnings Per Share for the same period.

Financial year ended Closing Share Price (cents) Earnings per share (cents)
30 June 2003 39.00 (0.53)
30 June 2004 66.00 (9.21)
30 June 2005 28.29 (8.70)
30 June 2006 16.00 (2.00)
30 June 2007 27.00 (2.40)

27

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

REMUNERATION REPORT (continued)

Fixed-term employment contracts

The Chief Executive Officer and Managing Director, Mr Neil Leggett , is employed under contract. The current employment contract is a 3 year contract that commenced on 15 December 2005 and terminates on 15 December 2008. The Company may commence negotiations to enter into a new employment contract with Mr Leggett at a time not less than 3 months prior to the end of the current term.

The terms of the present contract are:

  • Mr Leggett is paid fixed compensation of $310,000p.a. and is entitled to short -term and long-term incentives.

  • The amount of incentive paid is based on the achievement of annual performance criteria, which are set and evaluated by the Remuneration Committee. The criteria include both operational and share price performance milestones.

  • The Company or Mr Leggett may terminate this contract by giving 6 months’ written notice at any time on or after that date which is 6 months prior to the end of the term of the contract. Any vested options will be forfeited within a month of the resignation date or six months in special circumstances as deemed appropriate by the Board of Directors.

  • The Company may terminate this employment agreement by making a one-off lump sum payment of:

  • (i) An amount equal to twelve months’ fixed remuneration plus the amount which represents the average annual percentage of the short term incentive plan (STI) paid over the previous three years, or the duration of employment if such is less than three years; and

  • (ii) Pay any amount to which Mr Leggett is entitled in lieu of unused annual leave or long service leave, as at the termination date; and

  • (iii) An amount equal to the Black-Scholes valuation of the unexercised options issued to Mr Leggett as a Director at the termination date, and

  • (iv) The difference between the lease payout and the trade-in value of the vehicle normally driven by Mr Leggett.

  • The Company may terminate the contract if serious misconduct has occurred. Where termination with cause occurs, Mr Leggett is only entitled to that portion of remuneration that is fixed and any amount to which the employee is entitled in lieu of unused annual leave or long service leave, and only up to the date of termination. On termination with cause, any unvested options will be immediately be forfeited.

The Director Research and Product Development, Dr Michael Gerometta , is employed under contract. The current employment contract is a 2 year contract commencing on 1 April, 2006 and terminating on 31 March 2008. The Company may commence negotiations to enter into a new employment contract with Dr Gerometta at a time not less than 3 months prior to the end of the current term.

The terms of the present contract are:

  • Dr Gerometta is paid a fixed remuneration of $171,675 p.a. and is entitled to short-term and long-term incentives.

  • The amount of incentive paid is based on the achievement of annual performance criteria, which are set and evaluated by the Managing Director. The criteria include operational milestones.

  • The Company or Dr Gerometta may terminate this contract by giving 3 months’ written notice at any time on or after that date which is 3 months prior to the end of the term of the contract. Any vested options will be forfeited within a month of the resignation date or six months in special circumstances as deemed appropriate by the Board of Directors.

  • The Company may terminate this employment contract by making a one-off lump sum payment of:

  • (i) An amount equal to six months’ Fixed Remuneration.

  • (ii) Pay any amount to which Dr Gerometta is entitled in lieu of unused annual leave or long service leave, as at the termination date.

  • The Company may terminate the contract without notice if serious misconduct has occurred. Where termination with cause occurs, the employee is only entitled to any remuneration as at termination date and any amount to which the employee is entitled in lieu of annual leave or long service leave. On termination without notice by the Company, any unvested options will be forfeited. Vested options are forfeited if they are not exercised within one month of termination, or six months in special circumstances as deemed appropriate by the Board of Directors.

28

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

REMUNERATION REPORT (continued)

Fixed term employment contracts (continued)

The Director Clinical and Commercial Programs, Ms Helen Roberts , was employed under contract. The employment contract was a 2 year contract commencing on 1 April, 2006 and terminating on 31 March, 2008. Ms Roberts ceased employment on 13 July 2007.

The terms of the contract were:

  • Ms Roberts was paid a fixed remuneration of $163,500 p.a. and was entitled to short-term and long-term incentives.

  • The amount of incentive paid was based on the achievement of annual performance criteria, which were set and evaluated by the Managing Director. The criteria included operational milestones.

  • The Company or Ms Roberts could have terminated this contract by giving 3 months’ written notice given at any time on or after that date which was 3 months prior to the end of the term of the contract. Any vested options would be forfeited within a month of the resignation date or six months in special circumstances as deemed appropriate by the Board of Directors.

  • The Company could have terminated this employment contract by making a one-off lump sum payment of: (i) An amount equal to six months’ Fixed Remuneration.

  • (ii) Paying any amount of entitlements in lieu of unused annual leave or long service leave, as at the termination date.

  • The Company was able to terminate the contract without notice if serious misconduct occurred. Where termination with cause occurred, the employee would only have been entitled to any remuneration as at termination date and any amount to which the employee is entitled in lieu of annual leave or long service leave. On termination without notice by the Company , any unvested options would be forfeited. Vested options are forfeited if they are not exercised within one month of termination, or six months in special circumstances as deemed appropriate by the Board of Directors.

The Operations Manager, Mr Mark McArthur , is employed under contract. The current employment contract is a 2 year contract commencing on 1 April, 2006 and terminating on 31 March, 2008. The Company may commence negotiations to enter into a new employment contract with Mr McArthur at a time not less than 3 months prior to the end of the current term.

The terms of the present contract are:

  • Mr McArthur is paid a fixed remuneration of $148,785 p.a. and is entitled to short -term and long-term incentives.

  • The amount of incentive paid is based on the achievement of annual performance criteria, which are set and evaluated by the Managing Director. The criteria include operational milestones.

  • The Company or Mr McArthur may terminate this contract by giving 3 months’ written notice given at any time on or after that date which is 3 months prior to the end of the term of the contract. Any vested options will be forfeited within a month of the resignation date or six months in special circumstances as deemed appropriate by the Board of Directors.

  • The Company may terminate this employment contract by making a one-off lump sum payment of: (i) An amount equal to six months’ Fixed Remuneration.

  • (ii) Pay any amount to which Mr McArthur is entitled in lieu of unused annual leave or long service leave, as at the termination date.

  • The Company may terminate the contract without notice if serious misconduct has occurred. Where termination with cause occurs, the employee is only entitled to any remuneration as at termination date and any amount to which the employee is entitled in lieu of annual leave or long service leave. On termination without notice by the Company, any unvested options will be forfeited. Vested options are forfeited if they are not exercised within one month of termination, or six months in special circumstances as deemed appropriate by the Board of Directors.

29

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

REMUNERATION REPORT (continued)

Employment contracts (continued)

The Chief Executive Officer of Agenix Bio-Pharmaceutical (Shanghai) Co. Ltd, Mr. Jonathan Zhang is employed under contract. The current employment contract is a 3 year contract commencing on 17 April 2007 (with a deemed effective date of 1 March 2007) and terminating on 16 April 2010. The Company may commence negotiations to enter into a new employment contract with Mr. Zhang at a time not less than 3 months prior to the end of the current term.

The terms of the present contract are:

  • Mr. Zhang is paid a fixed remuneration of RMB1,200,000 (AUD$185,637) p.a. and is entitled to short-term and long-term incentives.

  • The amount of incentive paid is based on the achievement of annual performance criteria, which are set and evaluated by the Managing Director. The criteria include operational milestones.

  • The Company or Mr. Zhang may terminate this contract by giving 6 months’ written notice given at any time on or after that date which is 6 months prior to the end of the term of the contract. Any vested options will be forfeited within a month of the resignation date or six months in special circumstances as deemed appropriate by the Board of Directors.

  • The Company may terminate this employment contract where there is no breach by Mr. Zhang by making a one-off lump sum payment of:

  • (i) An amount equal to twelve months’ Fixed Remuneration plus the amount which represents the average annual percentage of the actual STI paid over the previous three years, or the duration of employment if such is less than three years.

  • (ii) Any amount of entitlements in lieu of unused annual leave or long service leave, as at the termination date.

  • The Company may terminate the contract without notice if serious misconduct has occurred. Where termination with cause occurs, the employee is only entitled to any remuneration as at termination date and any statutory leave entitlements. On termination without notice by the Company, any unvested options will be forfeited. Vested options are forfeited if they are not exercised within one month of termination, or six months in special circumstances as deemed appropriate by the Board of Directors.

The Chief Operating Officer of Agenix Bio-Pharmaceutical (Shanghai) Co. Ltd , Mr. Richard Wang , is employed under contract. The current employment contract is a 3 year contract commencing on 17 April, 2007 (with a deemed effective date of 1 March 2007) and terminating on 16 April, 2010. The Company may commence negotiations to enter into a new employment contract with Mr. Wang at a time not less than 3 months prior to the end of the current term.

The terms of the present contract are:

  • Mr. Wang is paid a fixed remuneration of RMB780,000 (AUD$120,664) p.a. and is entitled to short-term and long-term incentives.

  • The amount of incentive paid is based on the achievement of annual performance criteria, which are set and evaluated by the Managing Director. The criteria include operational milestones.

  • The Company or Mr. Wang may terminate this contract by giving 6 months’ written notice given at any time on or after that date which is 6 months prior to the end of the term of the contract. Any vested options will be forfeited within a month of the resignation date or six months in special circumstances as deemed appropriate by the Board of Directors.

  • The Company may terminate this employment contract where there is no breach by Mr. Wang by making a one-off lump sum payment of:

  • (i) An amount equal to twelve months’ Fixed Remuneration plus the amount which represents the average annual percentage of the actual STI paid over the previous three years, or the duration of employment if such is less than three years.

  • (ii) Any amount of entitlements in lieu of unused annual leave or long service leave, as at the termination date.

  • The Company may terminate the contract without notice if serious misconduct has occurred. Where termination with cause occurs, the employee is only entitled to any remuneration as at termination date and any statutory leave entitlements. On termination without notice by the Company, any unvested options will be forfeited. Vested options are forfeited if they are not exercised within one month of termination, or six months in special circumstances as deemed appropriate by the Board of Directors.

30

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

REMUNERATION REPORT (continued )

Remuneration of Key Management Personnel

Executives J. Zhang Chief Executive Officer for China (commenced 17 April 2007 – appointed Director 27 August 2007) R. Wang Chief Operating Officer for China (commenced 17 April 2007) G. Mastroianni Corporate Business Development Director M. Gerometta Director Research and Development M. McArthur Operations Manager C. Holmes Human Resources Manager H. Roberts Director Clinical and Commercial Programs (ceased employment 13 July 2007) P.Toye Manager of Research (ceased employment 17 November 2006)

The key management personnel of the Consolidated Entity are the executives (including the Directors of the Company ) who report to the CEO and Managing Director and their remuneration is tabled on the following page.

The remuneration paid or payable to Directors during the year, including payments made to companies was as follows:

Table 1: Directors remuneration for the year ended 30 June 2007

R. Govindan
2007
2006
Dr A. Lamotte
2007
2006
Salary &
Fees
Cash Bonus
Non
Monetary
Consulting
Fees
$
$
$
$
150,000
-
-
-
150,000
-
-
-
50,000
-
-
-
37,911
-
-
-
Short term
Superannuation
Termination
Benefits
$
$
13,500
-
13,500
-
4,500
-
3,412
-
Post Employment
Share
based
payments
Total
Total
Performance
Related
Options
$
$
-
163,500
0.00%
-
163,500
0.00%
-
54,500
0.00%
-
41,323
0.00%
K. Schlobohm
2007
2006
35,500
-
-
-
-
-
-
-
-
-
-
-
-
35,500
0.00%
-
-
0.00%
G.C. Ang (i)
2007
2006
N. Leggett
2007
27,688
-
-
-
-
-
-
-
176,833
121,660
70,536
2,492
-
-
-
58,556
-
30,180
0.00%
-
-
0.00%
156,798
584,383
20.82%

2006
142,275
72,842
46,478
39,240
-
120,698
421,533
17.28%
F.F. Wong (ii)
2007
22,446
-
-
-
2,020
-
-
24,466
0.00%

2006
50000
-
-
-
4500 54500
0.00%
J. Zhang
2007
2006
M. Davey (iii)
2007
2006
D. Home (iv)
2007
2006
Total Remuneration
2007
2006
,
56,770
-
-
-
-
-
-
-
21,388
-
-
-
55,000
-
-
-
-
-
-
-
109,125
-
38,222
-
540,625
121,660
70,536
-
544,311
72,842
84,700
-
,
5,109
-
-
-
1,925
-
4,950
-
-
-
11,425
542,080
88,102
-
77,027
542,080
,
-
61,879
0.00%
-
-
0.00%
-
23,313
0.00%
-
59,950
0.00%
-
-
0.00%
(139,722)
561,130
0.00%
156,798
977,721
(19,024)
1,301,936

(i) Resigned effective 31 August 2007

(ii) Resigned effective 12 December 2006

(iii) Resigned effective 20 November 2006

(iv) Resigned effective 15 December 2005

31

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

REMUNERATION REPORT (continued)

Table 2: Remuneration of key executives for the year ended 30 June 2007

Salary &
Fees
Cash Bonus
Non
Monetary
$
$
$
Short term
Superannuation
Termination
Benefits
$
$
Post Employment
Share
based
payments
Total
Total
Performance
Related
Options
$
$
S. Morrison
2007
2006
16,034
-
-
147,642
30,267
-
-
61,518
16,012
-
-
77,552
0.00%
29,608
223,529
13.54%
R. Wang(i)
2007
2006
M. Gerometta
2007
2006
H. Roberts
2007
2006
P. Toye
2007
2006
G. Mastroianni
2007
2006
M. McArthur
2007
36,900
-
-
-
-
-
140,383
41,850
875
124,960
27,351
-
150,000
33,300
-
126,679
34,170
-
39,848
-
-
87,682
12,275
-
135,904
44,640
-
131,402
33,937
-
119,463
49,000
10,537
3,321
-
-
-
24,655
-
20,645
-
16,497
-
14,476
-
3,511
-
8,996
-
30,449
-
25,780
-
16,110
-
-
40,221
0.00%
-
-
0.00%
18,629
226,392
18.49%
20,812
193,768
14.12%
18,629
218,426
15.25%
20,812
196,137
17.42%
-
43,359
0.00%
12,497
121,450
10.11%
19,073
230,066
19.40%
29,279
220,398
15.40%
11,491
206,601
23.72%
2006 97,963
21,593
-
10,760
-
12,497
142,813
15.12%
C. Holmes
2007
79,266
11,753
-
17,192
-
6,872
115,083
10.21%
2006 -
-
-
-
-
-
-
0.00%
B. Calvin
2007
2006
G. Taylor
2007
2006
-
-
-
61,158
-
8,094
72,173
10,197
-
-
-
5,541
98,325
49,036
78,015
-
-
0.00%
(75,601)
97,517
0.00%
7,277
216,698
4.71%
-
-
-
-
-
-
-
0.00%
Total Remuneration
2007
2006
789,971
190,740
11,412
777,486
159,593
8,094
160,771
139,533
102,210
98,325
81,971
1,374,398
49,904
1,195,612

(i) Appointed 01 March 2007

Table 3: Options granted as part of remuneration for the year ended 30 June 2007

Value of Total value of
options Value of options granted,
exercised options lapsed exercised and
Value per
Value of options
during the during the lapsed during
% of
Number option at
granted during the
year year the year remuner-
Grant date granted Vesting date grant date ^ year $'000 $'000 $'000 $'000 ation
N. Leggett 21 July 2006 500,000 21 July 2008 0.0467 23,350 - - 23,350 4.00%
N. Leggett 21 November 2006 3,000,000 15 December 2007 0.0193 57,900 - - 57,900 9.91%
N. Leggett 21 November 2006 1,000,000 15 December 2007 0.0005 500 - - 500 0.09%
M. Gerometta 21 July 2006 150,000 21 July 2008 0.0714 10,710 - - 10,710 4.73%
H. Roberts 21 July 2006 150,000 21 July 2008 0.0714 10,710 - - 10,710 4.90%
G. Mastroianni 21 July 2006 150,000 21 July 2008 0.0714 10,710 - - 10,710 56.15%
M. McArthur 21 July 2006 150,000 21 July 2008 0.0714 10,710 -
- 10,710 5.18%
C. Holmes 21 July 2006 67,500 21 July 2008 0.0714 4,820 - - 4,820 4.19%

^ From 1 July 2004, options granted as part of employees’ remuneration have been valued using the Black-Scholes model, which takes account factors including the option exercise price, the current level of volatility of the underlying share price, the risk free interest rate, expected dividends of the underlying share, current market price of the underlying share and expected life of the option.

There were no alterations to the terms and conditions of options granted as remuneration since their grant date.

On 21[st] July 2007, the Directors approved the issuance, subject to shareholder approval, of 3,120,000 options to Neil Leggett and 125,000 to Karl Schlobohm.

32

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

DIRECTORS’ MEETINGS

During the year, 7 Directors’ meetings were held.

The number of meetings of Directors (including meetings of committees of Directors) held during the year and the number of meetings attended by each Director was as follows:

attended by each Director was as follows:
Meetings Held
Whilst in
Board Office Attended
R. Govindan 7 7
Dr. A. Lamotte 7 3
K. Schlobohm1 5 5
GC. Ang2 3 3
N. Leggett 7 7
F.F. Wong 3 4 1
M. Davey 4 3 3

1) Mr Schlobohm was appointed a director on 20 November 2006.

2) Mr Ang was appointed a director on 12 December 2006.

3) Mr FF Wong resigned as a director on 12 December 2006.

4) Mr Davey resigned as a director on 20 November 2006.

Meetings Held
Whilst in
Audit Committee Office Attended
K. Schlobohm 1 1 1
G.C. Ang1 1 1
Dr. A. Lamotte 2 1 1
F.F. Wong 2 1 1

1) Mr Schlobohm was appointed Chairman of the Audit Committee on 12 December 2006 and Mr Ang was appointed the Audit Committee on that date.

2) Dr Lamotte resigned from the Audit Committee on 12 December 2006. Mr Wong also resigned from the Audit Committee on that 2) Dr Lamotte resigned from the Audit Committee on 12 December 2006. Mr Wong also resigned from the Audit Committee on that date.
Meetings Held
Whilst in
Remuneration Committee Office Attended
Dr. A. Lamotte 1 - -
R. Govindan 1 1
M. Davey 2 1 1

1) Dr Lamotte was appointed Chairman of the Remuneration Committee on 12 December 2006.

2) Mr Davey resigned from the Remuneration Committee on 20 November 2006.

COMMITTEE MEMBERSHIP

As at the date of this Report, the Company had an Audit Committee and a Remuneration Committee of the Board of Directors.

Members acting on the committees of the Board during the year were:

Audit Remuneration Mr. K Schlobohm Chairman (from 12 December 2006) Dr. A Lamotte Chairman (from 20 November 2006) Dr. A. Lamotte, Chairman (until 12 December 2006) Mr. Myles Davey, Chairman (until 20 November 2006) Mr. G. C. Ang (from 12 December 2006) Mr. Ravindran Govindan Mr. F.F. Wong (until 12 December 2006)

ROUNDING

The amounts contained in this Report and in the financial report have been rounded to the nearest $1,000 (where rounding is applicable) under the option available to the Company under ASIC Class Order 98/0100. The Company is an entity to which the Class Order applies.

33

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Directors’ Report continued

AUDITOR INDEPENDENCE AND NON-AUDIT SERVICES

The Directors acknowledge receipt of the independence declaration on Page 35 of this Report from the Company’s auditors, Ernst & Young.

NON-AUDIT SERVICES

The following non-audit services were provided by the entity’s auditors, Ernst & Young. The Directors are satisfied that the provision of nonaudit services is compatible with the general standard of independence for auditors imposed by the Corporations Act. The nature and scope of each type of non-audit service provided means that auditor independence was not compromised.

Ernst & Young received or are due to receive the following amounts for the provision of non-audit services:

R&D tax concession work

$20,000

Signed in accordance with a resolution of the Directors.

==> picture [118 x 68] intentionally omitted <==

______Neil Leggett CEO and Managing Director Brisbane, 30 September 2007

34

AGENIX LIMITED ANNUAL REPORT 2007

==> picture [558 x 795] intentionally omitted <==

AGENIX LIMITED ANNUAL REPORT 2007 35

AGENIX LIMITED Corporate Governance

Introduction

Agenix Limited is committed to best practice in the area of Corporate Governance in line with the ASX Corporate Governance Council’s Principles of Good Corporate Governance and Best Practice Regulations. However, given the size and ownership structure of the Company, the nature of its business activities, the stage of its development and the cost of strict and detailed compliance with all of the recommendations, it has adopted a range of slightly modified systems, procedures and practices which it considers will enable it to meet the principles of good corporate governance.

The Company’s practices are mainly consistent with those of the guidelines and where they do not correlate with the recommendations in the guidelines the Company considers that its adopted practices are appropriate to it. At the end of this statement a table is included detailing the recommendations with which the Company does not strictly comply.

All of the Corporate Governance policies listed below have been posted on the Company’s website.

  • Corporate Governance Practices and Policies;

  • Board Charter;

  • Matters Reserved;

  • Code of Conduct;

  • Continuous Disclosure Policy;

  • Disclosure of Information to Market;

  • Share Trading Policy;

  • Chief Executive Officer/Chief Financial Officer sign-off;

  • Director Appointment Procedures.

Principle 1 : Laying Solid Foundations for Management and Oversight

Role and Responsibilities of the Board

The Board of Directors – Role of the Board

The Board of Directors is responsible for the overall Corporate Governance of the Company. The Board recognises the need for the highest standards of behaviour and accountability. The Board of the Company has final responsibility for the management of the Company’s business and affairs.

This responsibility is addressed by the Board:

  • Contributing to approving the Company's goals and strategic direction and monitor implementation of those goals and strategies;

  • Monitoring the financial performance of the Company including adopting annual budgets and approving the Company's financial statements;

  • Approving and monitoring the progress of capital expenditure capital management acquisitions and divestitures;

  • Ensuring that adequate systems of internal compliance and control exist and are appropriately monitored for compliance;

  • Appointing and removing the Managing Director and ratifying the appointment or removal of the Chief Financial Officer and Company Secretary and reviewing the performance of senior management;

  • Ensuring significant business risks are identified and appropriately managed and review the systems of risk management at least annually;

  • Reviewing and ratifying codes of conduct and legal compliance; and

  • Disclosure of information to shareholders, the Australian Stock Exchange Limited and Australian Securities & Investments Commission.

The Board operates under a written charter (Board Charter) that identifies the functions reserved to the Board. Management of the day-to-day operations of the Company vests in the Managing Director who, together with the executive team, is accountable to the Board.

36 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Corporate Governance continued

Principle 2 : Structuring the Board to Add Value

Composition of the Board

The constitution of the Company provides that the number of Directors is to be not less than three nor more than seven. The Board is currently comprised of six Directors, four of whom (including the Chairman) hold their positions in a non-executive capacity. The Company’s constitution provides that at every Annual General Meeting, one third or the nearest third of the Directors and any other Director who has held office for three years or more since last being elected (excluding the Managing Director), are to retire from office. Each retiring Director under the constitution is eligible for re-election.

Independence

There are six Directors, four of whom are Non-Executive Directors (including the Chairman). The predominance of non-executive Directors and an independent Chairman separates the Board from the Company’s executive management and enshrines Board independence from management. This structure also provides the Company with the benefit of a diverse range of experience, qualifications and professional skills.

The Board (and each individual Director) is entitled to seek independent professional advice at the Company’s expense (subject to the reasonableness of the costs and Board consent) in the conduct of their duties for the Company.

- Principle 3 : Promotion of Ethical and Responsible Decision Making

Ethical Standards – Code of Conduct

The Board recognises the need to observe the highest standards of corporate practice and business conduct. Accordingly the Board has adopted a formal Code of Conduct to be followed by all employees and officers. The key aspects of this code are:

  • to act with honesty, integrity and fairness;

  • to act in accordance with the law;

  • to use Company resources and property appropriately.

Dealing in Shares

The Company has a formal written policy for Directors, officers and staff with respect to trading in the Company’s securities (Share Trading Policy). Directors and senior management (and their associates) are prohibited from engaging in short-term trading of Company securities.

The policy also restricts the selling of Company securities in specific circumstances (such as the period preceding the release of the Company’s financial results) and such other times whereby there is materially price sensitive information not yet available to the market. In addition, Directors, officers and senior management must notify the Managing Director or Company Secretary before they buy or sell Company securities and confirm once the transaction is complete.

Principle 4 : Safeguarding Integrity in Financial Reporting

The Company’s Managing Director and Chief Financial Officer provide a written statement to the Board (for the half-year and fullyear results) to the effect that the Financial Reports present a true and fair view of the Company’s financial condition, and the operational results are presented in accordance with the relevant accounting standards.

The Board has established an Audit Committee. At this stage, given the fact that four of the Board members are resident offshore, including three of the four Non-Executive/Independent Directors, there are only two members of the Committee. As such, this represents a departure from the ASX guidelines, which recommends a membership of three.

Under its Charter, this Committee supports the full Board and essentially acts in a review and advisory capacity in matters that require a more intensive review. Other Board committees may be established from time to time to address matters of special importance. An outline of the activities of the Committee is set out below.

37

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITEDAGENIX LIMITED Corporate Governance continuedCorporate Governance

Audit Committee Charter

Under the Charter this Committee must have a minimum of two members both of whom must be non-executive Directors. It should be noted that this represents a departure from the ASX guidelines. The Chairman of this committee must not be the Chairman of the Company. Under the Charter, the Audit Committee should include members who are financially literate (i.e. are able to read and understand financial statements). At least one member must have financial expertise (i.e. is a qualified accountant or other financial professional with experience of financial and accounting matters).

This Committee provides ongoing assurance in the areas of:

  • financial administration and reporting:

  • audit control and independence;

  • legal compliance;

  • applying accounting policies;

  • internal controls; and

  • risks oversight and management.

The primary role of this Committee is to assist the Board in:

  • verifying and safeguarding the integrity of the Company financial reporting;

  • establishing a sound system of risk oversight and management, and internal control; and

  • establishing a sound system of compliance with laws and regulations, internal compliance guidelines, policies, procedures and control systems and prescribed internal standards of behaviour.

Principle 5 : Making Timely and Balance Disclosure

All Directors, executives and staff are required to abide by all legal requirements, the Listing Rules of the Australian Stock Exchange (ASX) and the highest standards of ethical conduct. This includes compliance with the continuous disclosure requirements of the Listing Rules.

The Company Secretary is the person responsible for overseeing and co-ordinating disclosure of information to ASX as well as communicating with the ASX. The Company has written procedures for this purpose.

Principle 6 : Respecting the Rights of Shareholders

The Board’s fundamental responsibility to shareholders is to work towards meeting the Company’s objectives so as to add value for them.

In accordance with its Shareholders Communications Policy, the Board seeks to inform shareholders of all major developments affecting the Company by :

  • preparing half yearly and yearly financial reports;

  • making announcements in accordance with the listing rules and the continuous disclosure obligations;

  • hosting all of the above on the Company’s website;

  • annually, and more regularly if required, holding a general meeting of shareholders and forwarding to them the Annual Report together with notice of meeting and proxy form; and

  • voluntarily releasing other information which it believes is in the interests of shareholders.

The Annual General Meeting enables shareholders to receive the reports and participate in the meeting by attendance or by written communication. The Board seeks to notify all shareholders so they can be fully informed annually for the voting on the appointment of Directors and so as to enable them to have discussion at the Annual General Meeting with the Directors and/or the auditor of the Company who is invited to the Annual General Meeting.

38

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Corporate GovernanceCorporate Governance continued

Principle 7 : Recognising and Managing Risk

The Board has established an Audit Committee (discussed under Principle 4 above).

Under its Charter this Committee supports the full Board and essentially acts in a review and advisory capacity in matters that require a more intensive review. Other Board Committees may be established from time to time to address matters of special importance.

The Managing Director and the Company’s Chief Financial Officer provide a written statement to the Board that:

  • the statement they provide in relation to the integrity of the Company’s financial statements is founded on a sound system of risk management, and internal compliance and controls which implement the policies adopted by the Board; and

  • the Company’s risk management and internal compliance and controls system is operating efficiently and effectively in all material respects.

Principle 8 : Encouraging Enhanced Performance

The Board discusses and reviews it performance on an annual basis. The Board also discusses with each Director their requirements, performances and aspects of involvement in the Company.

The Company Secretary monitors Board policies and procedures, and advises on matters of Corporate Governance.

Principle 9 : Remunerate Fairly and Responsibly

A Remuneration Committee has been established. There is commentary on Directors remuneration in the section headed Directors’ Report in the Annual Report published each year.

There is a clear distinction made by the Company in remunerating the Board and remunerating executive management.

From time to time (although not regularly) a Non-Executive Director may undertake special duties or manage a particular project or process for the Company. In such instances, the non-executive Director is entitled to additional remuneration. At the recommendation of the Remuneration Committee, the Board may include a grant of options as part of this remuneration. Whilst such a grant would always be subject to shareholder approval, it represents a departure from 9.3 of the ASX guidelines.

One third of the Directors (excluding the Managing Director) retires annually in accordance with the Constitution and is free to seek reelection by shareholders.

Each member of the Board has committed to spending sufficient time to enable them to carry out their duties as a Director of the Company.

A maximum amount of remuneration for non-executive Directors is fixed by shareholders in general meeting and can be varied in that same manner.

39

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Corporate GovernanceCorporate Governance continued

~~SUPPLEMENTARY CORPORA~~ TE GOVERNANCE STATEMENT

Table of Departures and Explanations (from the Recommendations of the ASX Corporate Governance Council)

“Recommendation” Ref Departure Explanation
2.4 Separate Nomination
Committee
A separate Nomination
Committee has not been
formed.
The Board comprises six members each of whom
have varied skills & experiences and therefore
have valuable contributions to make in fulfilling
the role of a nomination committee member. A
Director will excuse himself/herself where there is
a personal interest ofconflict.
9.3 Non-Executive Director
Remuneration
Non-executive Directors have
been and may be granted
options.
Due to the nature of the Company’s activities, the
size of its Board and the workload of the
Directors, from time to time it may be determined
to grant options to the Non-Executive Directors
where they perform additional duties or accept
additional responsibilities. Shareholder approval
will be sought at a general meeting of
shareholders.
4.3 Audit Committee
Composition
Composition currently not at
a minimum of three members.
Committee is currently chaired by an independent
Director and has a membership of independent
Directors. However, given the current size of the
Board (six members) it is considered that a
Committee oftwois sufficient.

40

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED INCOME STATEMENT For the year ended 30 June 2007

Note CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Revenue 4(a) 1,098 833 196 87
Cost of sales (50) (144) - -
Gross profit 1,048 689 196 87
Other income 4(b) 6 381 6 -
Occupancy and administrative expenses (5,318) (3,666) (5,085) (2,952)
Research and development expenses 4(c) (5,304) (10,398) (29) 2
Executive termination payments (78) (662) (78) (662)
Write-back of executive share-based payments expense - 215 - 215
Impairment of financial assets - investment in subsidary - - (8,049) (10,186)
Corporate redundancies (62) - (62) -
Surplus lease space (183) - - -
Write-off unused tax credits (418) - (418) -
Finance Costs 4(d) (1,378) (735) (707) (734)
Other expenses (14) (38) (1) (55)
Loss before income tax (11,701) (14,214) (14,227) (14,285)
Income tax expense 5 - - - -
Loss after tax from continuing operations (11,701) (14,214) (14,227) (14,285)
Discontinued operation
Profit/(loss) after tax from discontinued operation 6 6,923 10,493 (115) (4,388)
Net loss for the period
(4,778) (3,721) (14,342) (18,673)
Attributable to:
Loss attributable to minority interest (5) - - -
Loss attributable to members of Agenix Limited (4,773) (3,721) (14,342) (18,673)
Earnings per share (cents per share) 7
- basic and diluted loss per share for the year
(cents per share)
(2.1) (2.0) (6.3) (9.9)
- basic and diluted loss per share from continuing operations
(cents per share)
(5.1) (7.5) (6.2) (7.6)

41

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED BALANCE SHEET As at 30 June 2007

Note CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Current assets
Cash and cash equivalents 9 3,782 8,743 2,444 5,976
Trade and other receivables 10 994 788 9,995 973
Inventories 11 4 - - -
Prepayments 192 137 77 22
Other current assets 234 - - -
5,206 9,668 12,516 6,971
Assets classified as held for sale 6 7,148 13,313 8 -
Total current assets 12,354 22,981 12,524 6,971
Non-current assets
Receivables 12 46 - - -
Shares in controlled entities 13 - - 3,833 11,810
Plant and equipment 14 5,529 572 51 74
Intangible assets and goodwill 15 15,102 101 43 70
Other non-current assets - - - -
20,677 673 3,927 11,954
Assets classified as held for sale 6 772 - - -
Total non-current assets 21,449 673 3,927 11,954
Total assets 33,803 23,654 16,451 18,925
Current liabilities
Trade and other payables 17 4,621 1,617 8,382 2,340
Derivative financial instruments 18 654 - 654 -
Interest and non-interest bearing loans and borrowings 19(a) 666 4,976 - 4,976
Interest and non-interest bearing loans and borrowings 19(a) 2,262 - - -
Provisions 20 250 342 135 186
8,453 6,935 9,171 7,502
Liabilities directly associated with assets classified as held for sale 6 3,399 2,167 142 149
Total current liabilities 11,852 9,102 9,313 7,651
Non-current liabilities
Interest and non-interest bearing loans and borrowings 19(b) 2,063 - - -
Provisions 20 136 341 118 316
Total non-current liabilities 2,199 341 118 316
Total liabilities 14,051 9,443 9,431 7,967
Net assets 19,752 14,211 7,020 10,958
Equity
Issued capital 21(a) 59,392 50,114 59,392 50,114
Share option reserve 21(f) 4,598 3,472 4,598 3,472
FX translation reserve (85) - - -
Loss attributable to Minority Interest (5) - - -
Accumulated losses 21(e) (44,148) (39,375) (56,970) (42,628)
Total equity 19,752 14,211 7,020 10,958

42 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED CASH FLOW STATEMENT

For the year ended 30 June 2007

Note CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Cash flows from operating activities
Receipts from customers 9,580 16,830 5 (9)
Payments to suppliers, employees and others (16,012) (14,776) (4,833) (3,685)
Payments relating to ThromboView
®project
(4,454) (10,096) - -
START grant - 223 - -
Income tax paid (2) (81) (2) -
Interest received 338 140 196 87
Borrowing costs (30) (723) (28) (723)
Net operating cash flows 9 (10,580) (8,483) (4,662) (4,330)
Cash flows from investing activities
Payments for property, plant, equipment and other assets (27) (191) (16) -
Payment for acquistion of subsidiaries 24 (9,009) - (72) -
Proceeds from the sale of discontinued operations (net of costs) 4,649 8,307 - 1,754
Proceeds from the sale of plant and equipment 5,563 45 - -
Proceeds from the sale of Industrial Biosystems PtyLtd 165 211 165 211
Net investing cash flows 1,341 8,372 77 1,965
Cash flows from financing activities
Repayment of borrowings (5,000) (5,650) (5,000) (5,650)
Proceeds from issue of shares from capital raising (net of costs) 21(c) 9,278 12,450 9,278 12,450
Loans to other entities - - (3,225) 1,539
Net financing cash flows 4,278 6,800 1,053 8,339
Net increase/(decrease) in cash held (4,961) 6,689 (3,532) 5,974
Cash at the beginningof the financialperiod 8,743 2,054 5,976 2
Cash at the end of the financialperiod 9 3,782 8,743 2,444 5,976

43

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED STATEMENT OF CHANGES IN EQUITY

For the year ended 30 June 2007

Share option Total
Issued capital Accumulated losses Minority reserves FX translation equity
$ 000 $ 000 Interest $000 $ 000 reserve $000 $ 000
CONSOLIDATED
At 1 July 2006 50,114 (39,375) - 3,472 - 14,211
-
Currency translation differences - - - - (85) (85)
Cost of issue of share capital (953) - - - - (953)
Total income and expenses for the year recognised directly in equity (953) - - - (85) (1,038)
Loss for the period - (4,773) (5) - - (4,778)
Total income/expense for the year - (4,773) (5) - - -
Share-based payments (note 21(f)) - - 1,126 - 1,126
Issue of share capital 10,231 - - - 10,231
At 30 June 2007 59,392 (44,148) (5) 4,598 (85) 19,752
.
Share option Total
Issued capital Accumulated losses Minority reserves FX translation equity
$ 000 $ 000 Interest $000 $ 000 reserve $000 $ 000
At 1 July 2005 37,664 (35,654) - 3,384 - 5,394
-
Cost of issue of share capital (898) - - - - (898)
Total income and expenses for the year recognised directly in equity (898) - - - - (898)
Loss for the period - (3,721) - . - (3,721)
Total income/expense for the year - (3,721) - - - -
Write-back of share based payments expense - - - 88 - 88
Loss attributable to Outside Equity - - - - -
Issue of share capital 13,348 - - - - 13,348
At 30 June 2006 50,114 (39,375) - 3,472 - 14,211
Share option Total
Issued capital Accumulated losses Minority reserves FX translation equity
$ 000 $ 000 Interest $000 $ 000 reserve $000 $ 000
PARENT
At 1 July 2006 50,114 (42,628) - 3,472 - 10,958
Cost of issue of share capital (953) - - - - (953)
Total income and expenses for the year recognised directly in equity (953) - - - - (953)
Loss for the period - (14,342) - - - (14,342)
~~Total income / expense for the year~~ - (14,342) - - - -
Share-based payments (note 21(f)) - - - 1,126 - 1,126
Issue of share capital 10,231 - - - - 10,231
At 30 June 2007 59,392 (56,970) - 4,598 - 7,020
Share option Total
Issued capital Accumulated losses Minority reserves FX translation equity
$ 000 $ 000 Interest $000 $ 000 reserve $000 $ 000
At 1 July 2005 37,664 (23,955) - 3,384 - 17,093
~~Cost of issue of share capital~~ ~~(898)~~ - - - - (898)
Total income and expenses for the year recognised directly in equity (898) - - - - (898)
Loss for the period - (18,673) - - - (18,673)
Total income / expense for the year - (18,673) - - - -
Cost of share-based payments - - - 88 - 88
Issue of share capital 13,348 - - - - 13,348
At 30 June 2006 50,114 (42,628) - 3,472 - 10,958

44

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

1. CORPORATE INFORMATION

The financial Report of Agenix Limited (the Company) for the year ended 30 June 2007 was authorised for issue in accordance with a resolution of the Directors on 30[th] September 2007.

Agenix Limited is a Company limited by shares incorporated in Australia whose shares are publicly traded on the Australian Stock Exchange. (ASX Code: AGX)

The nature of the operations and principal activities of the Consolidated Entity are described in Note 3.

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

(a) Basis of preparation

The financial Report is a general purpose financial Report, which has been prepared in accordance with the requirements of the Corporations Act 2001 , and Australian Accounting Standards. The financial Report has been prepared on a historical cost basis, except for derivative financial instruments, which have been measured at fair value.

(b) Statement of compliance

The financial report complies with Australian Accounting Standards, which include Australian equivalents to International Financial Reporting Standards (AIFRS). Compliance with AIFRS ensures that the financial report, comprising the financial statements and notes thereto, complies with International Financial Reporting Standards (IFRS).

Australian Accounting Standards that have recently been issued or amended but are not yet effective have not been adopted for the annual reporting period ended 30 June 2007. The Company’s assessment of the impact of the new standards and interpretations considered relevant to it is set out below:

i. AASB 7 Financial Instruments: Disclosures and AASB 2005-10 Amendments to Australian Accounting Standards [AASB 132, AASB 101, AASB 114, AABS 117, AASB 133, AASB 139, AASB 1, AASB 4, AASB 1023, and AASB 1038]

AASB 7 and AASB 2005-10 are applicable to annual reporting periods beginning on or after 1 January 2007. The Company has not adopted the standards early. Application of the standards will not affect any of the amounts recognised in the financial statements, but is likely to impact the type of information disclosed in relation to the Company’s financial instruments.

ii. AASB Interpretation 10 Interim Financial Reporting and Impairment

AASB Interpretation 10 is applicable to reporting periods commencing on or after 1 November 2006. The Company has not recognised an impairment loss in relation to goodwill in an interim reporting period but subsequently reversed the impairment loss in the annual report. Application of the interpretation therefore does not have an impact on Company’s financial statement.

iii. AASB 2007-4 Amendments to Australian Accounting Standards arising from ED 151 and Other Amendments [AASB 1, 2, 3, 4, 5, 6, 1023, and 1038]

AASB 2007-4 is applicable to reporting periods commencing on or after 1 July 2007. As a result of this guidance the Company expects to reduce the extent of some disclosures in the financial report.

iv. AASB 8 Operating Segments and AASB 2007-3 Amendments to Australian Accounting Standards [AASB 5, 6, 102, 107, 119, 127, 134, 136, 1023 and 1038]

AASB 8 is applicable to reporting periods on or after 1 January 2009. AASB 8 is a disclosure standard so will have no direct impact on the amounts included in the financial statements.

45

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)

(c) Basis of consolidation

The consolidated financial statements comprise the financial statements of Agenix Limited and its subsidiaries ('the Group') as at 30 June each year.

The financial statements of subsidiaries are prepared for the same Reporting period as the parent Company, using consistent accounting policies.

All intercompany balances and transactions, including unrealised profits arising from intra-group transactions, have been eliminated in full. Unrealised losses are eliminated unless costs cannot be recovered.

Subsidiaries are consolidated from the date on which control is transferred to the Group and cease to be consolidated from the date on which control is transferred out of the Group.

Where there is loss of control of a subsidiary, the consolidated financial statements include the results for the part of the Reporting period during which Agenix Limited has control.

Minority interests not held by the group are allocated their share of net profits after tax in the income statement and are presented within equity in the consolidated balance sheet, separately from parent shareholders’ equity.

46

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)

(d) Significant accounting estimates and assumptions

The carrying amount of certain assets and liabilities are often determined based on estimates and assumptions of future events. The key estimates and assumptions that have a significant risk of causing a material adjustment to the carrying amounts of certain assets and liabilities within the next annual reporting period are:

Impairment of goodwill and intangibles with indefinite lives

The Company determines whether goodwill and intangibles with indefinite lives are impaired at least on an annual basis. This requires an estimation of the recoverable amount of cash-generating units to which the goodwill and intangibles with indefinite lives are allocated.

Share-based payment transactions

The Company measures the cost of equity-settled transactions with employees by reference to the fair value of the equity instruments at the date at which they are granted. The fair value is determined by the Black-Scholes option-pricing formula detailed in Note 16.

(e) Foreign currency translation

Both the functional and presentation currency of Agenix Limited and all its subsidiaries are initially recorded in the functional currency at the exchange rates ruling at the date of the transaction. Monetary assets and liabilities denominated in foreign currencies are retranslated at the rate of exchange ruling at the balance sheet date.

All differences in the Consolidated Financial Report are taken to the income statement with the exception of differences on foreign currency borrowings that provide a hedge against a net investment in a foreign entity. These are taken directly to equity until the disposal of the net investment, at which time they are recognised in the income statement. Tax charges and credits attributable to exchange differences on those borrowings are also recognised in equity.

Non-monetary items that are measured in terms of historical cost in a foreign currency are translated using the exchange rate as at the date of the initial transaction. Non-monetary items measured at fair value in a foreign currency are translated using the exchange rates at the date when the fair value was determined.

As at the reporting date the assets and liabilities of these overseas subsidiaries are translated into the presentation currency of Agenix Limited at the rate of exchange ruling at the balance sheet date and the income statements are translated at the weighted average exchange rates for the period.

The exchange differences arising on the retranslation are taken directly to a separate component of equity.

On disposal of a foreign entity, the deferred cumulative amount recognised in equity relating to that particular foreign operation is recognised in the income statement.

  • (f) Property, plant and equipment

Plant and equipment is stated at cost, less accumulated depreciation.

Land and buildings are measured at cost, less accumulated depreciation.

Depreciation is calculated on a straight-line over the estimated useful life of the asset as follows:

Buildings – over 40 to 50 years

Plant and equipment – over 3 to 20 years

Impairment

The carrying values of plant and equipment are reviewed for impairment when events or changes in circumstances indicate the carrying value may not be recoverable.

For an asset that does not generate largely independent cash inflows, the recoverable amount is determined for the cash-generating unit to which the asset belongs.

If any such indication exists and where the carrying values exceed the estimated recoverable amount, the assets or cash-generating units are written down to their recoverable amount.

The recoverable amount of plant and equipment is the greater of fair value less costs to sell and value in use. In assessing value in use, the estimated future cash flows are discounted to their present value using a pre-tax discount rate that reflects current market assessments of the time value of money and the risks specific to the asset.

47

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITEDAGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTSNOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007For the year ended 30 June 2007

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)

(g) Borrowing costs

Borrowing costs are recognised as an expense when incurred.

(h) Intangible assets

Intangibles acquired both separately and from a business combination

Intangible assets acquired separately are capitalised at cost and from a business combination are capitalised at fair value as at the date of acquisition. Following initial recognition, intangible assets are carried at cost less any impairment losses. Internally generated intangible assets created within the business are not capitalised and expenditure is charged against profits in the period in which the expenditure is incurred.

The useful lives of intangible assets are assessed to be either finite or indefinite. Intangible assets with finite lives are amortised over the useful life and assessed for impairment whenever there is an indication that the intangible asset may be impaired. The amortisation period and the amortisation method for an intangible asset with a finite useful life are reviewed at least at each financial year-end. Changes in the useful life or the expected pattern of consumption of future economic benefits embodied in the asset is accounted for by changing the amortisation period or method, as appropriate, which is a change in accounting estimates. The amortisation expense on intangible assets with finite lives is recognised in the income statement in the expense category consistent with the function of the intangible asset.

Intangible assets with indefinite useful lives (other than goodwill) are tested for impairment annually either individually or at the cashgenerating unit level. Such intangibles are not amortised. The useful life of an intangible asset is reviewed annually to determine whether indefinite life assessment continues to be supportable. If not, the change in the useful life assessment from indefinite life to finite is made on a prospective basis.

Research and development costs

Research costs are expensed as incurred. An intangible asset arising from development expenditure on a internal project is recognised only when the Group can demonstrate the technical feasibility of completing the intangible asset so that it will be available for use or sale, its intention to complete and its ability to use or sell the asset, how the asset will generate future economic benefits, the availability of resources to complete the development and the ability to measure reliably the expenditure attributable to the intangible asset during its development. Following the initial recognition of the development expenditure, the cost model is applied requiring the asset to be carried at cost less any accumulated amortisation and accumulated impairment losses. Any expenditure carried forward is amortised over the period of expected future sales from the related project.

The carrying value of an intangible asset arising from development expenditure is tested for impairment annually when the asset is not yet in use, or more frequently when an indicator of impairment arises during the reporting year.

A summary of the policies applied to the Group's intangible assets is as follows:

Patents and Licences Brand Names Software Intellectual Property
Useful lives Finite Indefinite Finite Indefinite
Method used 5-10 years – straight line Not depreciated or re-
valued
1-5 years – straight line Not Depreciated
Internally
generated /
Acquired
Acquired Acquired Acquired Acquired
Impairment test /
Recoverable
amount testing
Amortised method
reviewed at each
financial year-end;
Reviewed annually for
indicator of impairment
Annually and where an
indicator of impairment
exists
Amortised method
reviewed at each
financial year-end;
Reviewed annually for
indicator of impairment
Annually and where an
indicator of impairment
exists

Gains or losses arising from de-recognition of an intangible asset are measured as the difference between the net disposal proceeds and the carrying amount of the asset and are recognised in the income statement when the asset is derecognised.

48

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)

(i) Impairment of Assets

The Group assesses at each reporting date whether there is any indication that an asset may be impaired. If any such indication of impairment exists, the Group makes an estimate of the asset’s recoverable amount. An asset’s recoverable amount is the higher of its fair value less costs to sell and value in use and is determined for an individual asset, unless the asset does not generate cash inflows that are largely independent of those from other assets or groups of assets and the value in use cannot be estimated to be close to its fair value. In such cases the asset is tested for impairment as part of the cash-generating unit to which it belongs. When the carrying amount of an asset or cash-generating unit is considered impaired and is written down to its recoverable amount.

In assessing value in use, the estimated future cash flows are discounted to their present value using a pre-tax discount rate that reflects current market assessments of the time value of money and the risks specific to the asset. Impairment losses relating to continuing operations are recognised in those expense categories consistent with the function of the impaired asset unless the asset is carried at the revalued amount (in which the impairment loss is treated as a revaluation decrease).

An assessment is made at each reporting date as to whether there is any indication that previously recognised impairment losses may no longer exist or may have decreased. If such indication exists, the recoverable amount is estimated. A previously recognised impairment loss is reversed only if there has been a change in the estimate used to determine the asset’s recoverable amount since the last impairment loss was recognised. If that is the case the carrying amount of the asset is increased to its recoverable amount. That increased amount is increased to its recoverable amount. That increased amount cannot exceed the carrying amount that would have been determined, net of depreciation, had no impairment loss been recognised for the asset in prior years. Such reversal is recognised in profit or loss unless the asset is carried at revalued amount, in which case the reversal is treated as a revaluation increase. After such a reversal the depreciation charged is adjusted in future periods to allocate the asset’s revised carrying amount, less any residual value, on a systematic basis over its remaining useful life.

(j) Inventories

Inventories are valued at the lower of cost and net realisable value.

Costs incurred in bringing each product to its present location and condition is accounted for as follows:

  • Raw materials – purchase cost on a first-in, first-out basis;

  • Finished goods and work-in-progress – cost of direct materials and labour and a proportion of manufacturing overheads based on normal operating capacity but excluding borrowing costs.

Net realisable value is the estimated selling price in the ordinary course of business, less estimated costs of completion and the estimated costs necessary to make the sale.

(k) Trade and other receivables

Trade receivables, which generally have 30-60 day terms, are recognised and carried at original invoice amount less an allowance for any uncollectible amounts.

An allowance for doubtful debts is made when there is objective evidence that the Group will not be able to collect the debts.

(l) Cash and cash equivalents Cash and short-term deposits in the balance sheet comprise cash at bank and in hand and short-term deposits with an original maturity of seven days or less.

For the Cash Flow Statement, cash and cash equivalents consist of cash and cash equivalents as defined above.

(m) Interest-bearing loans and borrowings

All loans and borrowings are initially recognised at cost, being the fair value of the consideration received net of issue costs associated with the borrowing.

After initial recognition, interest-bearing loans and borrowings are subsequently measured at amortised cost using the effective interest method. Amortised cost is calculated by taking into account any issue costs, and any discount or premium on settlement.

Gains and losses are recognised in the income statement when the liabilities are derecognised.

49

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)

(n) Provisions

Provisions are recognised when the Group has a present obligation (legal or constructive) as a result of a past event, it is probable that an outflow of resources embodying economic benefits will be required to settle the obligation and a reliable estimate can be made of the amount of the obligation.

Where the Group expects some or all of a provision to be reimbursed, for example under an insurance contract, the reimbursement is recognised as a separate asset but only when the reimbursement is virtually certain. The expense relating to any provision is presented in the income statement net of any reimbursement.

If the effect of the time value of money is material, provisions are determined by discounting the expected future cash flows at a pretax rate that reflects current market assessments of the time value of money and, where appropriate, the risks specific to the liability.

Where discounting is used, the increase in the provision due to the passage of time is recognised as a finance cost.

(o) Employee leave benefits

Wages, salaries, annual leave and sick leave

Liabilities for wages and salaries, including non-monetary benefits, annual leave and accumulating sick leave expected to be settled within 12 months of the Reporting date are recognised in the other payables in respect of employees’ services up to Reporting date. They are measured at the amounts expected to be paid when the liabilities are settled. Liabilities for non-accumulating sick leave are recognised when the leave is taken and are measured at the rates paid or payable.

Long service leave

The liability for long service leave is recognised in the provision for employee benefits and measured as the present value of expected future payments to be made in respect of services provided by employees up to the Reporting date using the projected unit credit method. Consideration is given to expected future wage and salary levels, experience of employee departures, and periods of service. Expected future payments are discounted using market yields at the Reporting date on national government bonds with terms to maturity and currencies that match, as closely as possible, the estimated future cash outflows.

(p) Leases

Leases where the lessor retains substantially all the risks and benefits of ownership of the asset are classified as operating leases. Initial direct costs incurred in negotiating an operating lease are added to the carrying amount of the leased asset and recognised over the lease term on the same bases as the lease income.

Operating lease payments are recognised as an expense in the income statement on a straight-line basis over the lease term.

(q) Share-based payment transactions

The Group provides benefits to employees (including Directors) of the Group in the form of share-based payment transactions, whereby employees render services in exchange for rights over shares (‘equity-settled transactions’).

The current plan in place to provide these benefits is the Employee Option Plan (EOP), which provides benefits to all employees including Directors and senior executives.

The cost of these equity-settled transactions with employees is measured by reference to the fair value at the date at which they are granted. The fair value is determined by the Black-Scholes option-pricing model.

In valuing equity-settled transactions, no account is taken of any performance conditions, other than conditions linked to the price of the shares of Agenix Limited (‘market conditions’). The cost of equity-settled transactions is recognised, together with a corresponding increase in equity, over the period in which the performance conditions are fulfilled, ending on the date on which the relevant employees become fully entitled to the award (‘vesting date’).

The cumulative expense recognised for equity-settled transactions at each Reporting date until vesting date reflects (i) the extent to which the vesting period has expired and (ii) the number of awards that, in the opinion of the Directors of the Group, will ultimately vest. This opinion is formed based on the best available information at balance date. No adjustment is made for the likelihood of market performance conditions being met, as the effect of these conditions is included in the determination of fair value at grant date.

No expense is recognised for awards that do not ultimately vest, except for awards where vesting is conditional upon a market condition.

50

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)

(q) Share-based payment transactions (continued)

Where the terms of an equity-settled award are modified, as a minimum an expense is recognised as if the terms had not been modified. In addition, an expense is recognised for any increase in the value of the transaction as a result of the modification, as measured at the date of modification.

Where an equity-settled award is cancelled, it is treated as if it had vested on the date of cancellation, and any expense not yet recognised for the award is recognised immediately. However, if a new award is substituted for the cancelled award, and designated as a replacement award on the date that it is granted, the cancelled and new award are treated as if they were a modification of the original award, as described in the previous paragraph.

The dilution effect, if any, of outstanding options is reflected as additional share dilution in the computation of earnings per share.

(r) Government grants

Government grants are recognised at their fair value where there is reasonable assurance that the grant will be received and all attaching conditions will be complied with.

When the grant relates to an expense item, it is recognised as income over the periods necessary to match the grant on a systematic basis to the costs that it is int ended to compensate.

Where the grant relates to an asset, the fair value is credited to a deferred income account and is released to the income statement over the expected useful life of the relevant asset by equal annual instalments.

(s) Tax consolidation

The Company and all its wholly owned Australian resident subsidiary companies are part of a consolidated tax group under Australian taxation law. Agenix Limited is the head Company. Tax expense / income, deferred tax liabilities and deferred tax assets arising from temporary differences of the members of the consolidated tax group are recognised in the separate financial statements of the members of the consolidated tax group. Current tax liabilities and assets and deferred tax assets arising from carried forward tax losses are recognised by the Company (as head Company of the consolidated tax group).

Due to the existence of a tax funding agreement between the companies in the consolidated tax group, amounts are recognised as payable to or receivable by the Company, and each member of the consolidated tax group, in relation to the tax contribution amounts paid or payable, between the Company and the other members of the consolidated tax group in accordance with the agreement.

(t) Revenue

Revenue is recognised to the extent that it is probable that the economic benefits will flow to the Group and the revenue can be reliably measured. The following specific recognition criteria must also be met before revenue is recognised:

Sale of goods

Revenue is recognised when the significant risks and rewards of ownership of the goods have passed to the buyer and can be measured reliably. Revenue from the sale of products and services is recognised upon transfer to the customer of the significant risks and rewards of ownership. This is generally when goods are dispatched to customers.

Interest

Revenue is recognised as the interest accrues (using the effective interest method, which is the rate that exactly discounts estimated future cash receipts through the expected life of the financial instrument) to the net carrying amount of the financial asset.

Rental revenue

Rental income arising on investment properties is accounted for on a straight-line basis over the lease term. Contingent rental income is recognised as income in the periods in which it is earned.

Royalties and licences

Royalty and licence revenue is brought to account on an accrual basis to the extent that it is probable that the economic benefit will flow to the entity and can be reliably measured.

Clinical trial services revenue

Clinical trial services revenue is brought to account on an accrual basis to the extent that it is probable that the economic benefit will flow to the entity and can be reliably measured.

Contract development services revenue

Contract development services revenue is brought to account on an accrual basis to the extent that it is probable that the economic benefit will flow to the entity and can be reliably measured.

51

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)

(u) Income taxes

Deferred income tax is provided on all temporary differences at the balance sheet date between the tax bases of assets and liabilities and their carrying amounts for financial Reporting purposes.

Deferred income tax liabilities are recognised for all taxable temporary differences:

  • except where the deferred income tax liability arises from the initial recognition of an asset or liability in a transaction that is not a business combination and, at the time of the transaction, affects neither the accounting profit nor taxable profit or loss; and

  • in respect of taxable temporary differences associated with investments in subsidiaries, except where the timing of the reversal of the temporary differences can be controlled and it is probable that the temporary differences will not reverse in the foreseeable future.

Deferred income tax assets are recognised for all deductible temporary differences, carry-forward of unused tax assets and unused tax losses, to the extent that it is probable that taxable profit will be available against which the deductible temporary differences, and the carry-forward of unused tax assets and unused tax losses can be utilised:

  • except where the deferred income tax asset relating to the deductible temporary difference arises from the initial recognition of an asset or liability in a transaction that is not a business combination and, at the time of the transaction, affects neither the accounting profit nor taxable profit or loss; and

  • in respect of deductible temporary differences associated with investments in subsidiaries, deferred tax assets are only recognised to the extent that it is probable that the temporary differences will reverse in the foreseeable future and taxable profit will be available against which the temporary differences can be utilised.

The carrying amount of deferred income tax assets is reviewed at each balance sheet date and reduced to the extent that it is no longer probable that sufficient taxable profit will be available to allow all or part of the deferred income tax asset to be utilised.

Deferred income tax assets and liabilities are measured at the tax rates that are expected to apply to the year when the asset is realised or the liability is settled, based on tax rates (and tax laws) that have been enacted or substantively enacted at the balance sheet date.

Income taxes relating to items recognised directly in equity are recognised in equity and not in the income statement.

  • (v) Other taxes

Revenues, expenses and assets are recognised net of the amount of GST except:

  • � where the GST incurred on a purchase of goods and services is not recoverable from the taxation authority, in which case the GST is recognised as part of the cost of acquisition of the asset or as part of the expense item as applicable; and

  • � receivables and payables are stated with the amount of GST included.

The net amount of GST recoverable from, or payable to, the taxation authority is included as part of receivables or payables in the balance sheet. Cash flows are included in the Cash Flow Statement on a gross basis and the GST component of cash flows arising from investing and financing activities, which is recoverable from, or payable to, the taxation authority are classified as operating cash flows.

Commitments and contingencies are disclosed net of the amount of GST recoverable from, or payable to, the taxation authority.

(w) Derivative financial instruments

The Group uses derivative financial instruments such as foreign currency contracts to economically hedge its risks associated with foreign currency fluctuations. Such derivative financial instruments are stated at fair value on the date on which the derivative contract is entered into and are subsequently remeasured at fair value. Derivatives are carried as assets when their fair value is positive and as liabilities when their fair value is negative.

Forward exchange contracts

Forward exchange contracts are entered into where agreements are made to buy or sell specified amounts of foreign currencies in the future at a predetermined exchange rate. The objective is to match the contract with anticipated future cash flows from sales and purchases in foreign currencies, to protect against the possibility of loss from future exchange fluctuations. The forward exchange contracts are usually for no longer than 6 months.

The fair value of forward exchange contracts is calculated by reference to current forward exchange rates for contracts with similar maturity profiles.

(x) Trade and other payables

Trade payables and other payables at amortised costs and represent liabilities for goods and services provided to the Group prior to the end of the financial year that are unpaid and arise when the Group becomes obligated to make future payments in respect of the purchase of these goods and services.

52

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (continued)

(y)

Earnings per share

Basic earnings per share amounts are calculated by dividing net profit for the year attributable to ordinary equity holders of the parent by the weighted average number of ordinary shared outstanding during the year.

Diluted earnings per share amounts are calculated by dividing the net profit attributable to ordinary equity holders of the parent by the weighted average number of ordinary shares outstanding during the year plus the weighted average number of ordinary shares that would be issued on the conversion of all of the dilutive potential ordinary shares into ordinary shares.

(z) Going concern

The going concern basis of accounting contemplates the continuity of normal business activities and the realisation of assets and settlement of liabilities. This Report adopts the going concern basis.

The Company and the Consolidated Entity have incurred an operating loss after income tax of $14.227 million and $4.773 million (2006: $18.673 million and $3.721 million respectively).

The Directors believe that the Company and the Consolidated Entity continue to be going concerns and that they will be able to pay their debts as and when they fall due for a period of 12 months from the date of signing this Report due to the following:

  • (i) As at 30 June 2007 the Consolidated Entity had net assets of $19.757 million. At the same date, the market capitalisation of Agenix Limited was in excess of $90 million (including shares currently under escrow).

  • (ii) As at 30 June 2007, Assets of the Consolidated Entity exceeded Liabilities by a ratio of 3.48 : 1.

  • (iii) The Consolidated Entity had cash at its disposal of $3.846 million at 30 June 2007.

  • (iv) The Consolidated Entity had no substantive borrowings from banks or other financial institutions at 30 June 2007. As of the date of this Report, that position had not changed.

  • (v) On the 6[th] and 16[th] of August 2007, the Company announced the successful placement to institutional and sophisticated investors in Australia and Asia raising $7.15 million before costs.

  • (vi) The ThromboView[®] project has go/no go decision points throughout the project and, theoretically, at any point where the project was not considered viable, future expenditure would not be required. The Directors believe that the Company has adequate funding alternatives to fund the forecast cost of Phase II clinical trials for both DVT (deep vein thrombosis) and PE (pulmonary emboli). The Directors will continually evaluate the timing of cost requirements for manufacture of material and commercialisation of ThromboView[®] .

  • (vii) The impending commercialisation of SHRG’s anti-hepatitis B virus drug called YouHeDing in China, which is expected to result in immediate cash-flows for the Consolidated Entity upon approval.

  • (viii) As a listed public Company, Agenix has access to shareholders or other investors from which to seek capital at relatively short notice.

3. SEGMENT REPORTING

Primary segment

The business segments below derive revenue from the following products and operations:

Continuing operations

  • (i) Monoclonal antibody development

  • (ii) Molecular biology (iii) Agenix Bio-pharmaceuticals (Shanghai, PRC)

Development of monoclonal antibody-based products. Manufacture and sale of biomedical products.

Development, manufacture and sale of pharmaceuticals.

Discontinued operations

  • (iv) Medical diagnostics

  • (v) Pharmaceuticals

  • (vi) Industrial Biosystems

Development, manufacture and sale of human and veterinary diagnostics.

Residual items from sale of Milton Pharmaceuticals. Residual items from sale of non-core subsidiary.

53

AGENIX LIMITED ANNUAL REPORT 2007

Total Operations Consolidated Total $ 000 9,579 196 9,775 1,423 (6,196) (4,773) (5) - (4,778) 31,088 2,715 33,803 28,643 (14,592) 14,051 25 (279) (44) (67) (365) (10,580) 1,341 4,278
Total $ 000 8,677 - 8,677 6,923 - 6,923 - - 6,923 7,912 8 7,920 3,399 - 3,399 - - - 163 163 1,777 10,377 (12,154)
Discontinued Operations Pharma-
Industrial
Eliminations /
ceuticals
Biosystems
Unallocated
$ 000
$ 000
$ 000
-
-
-
260
-
-
-
-
-
-
-
-
134
-
-
-
-
-
-
-
-
-
-
-
-
-
163
-
-
163
(399)
-
-
-
165
-
399
(165)
-
Medical diagnostics $ 000 8,677 6,663 - 7,912 3,265 - - - - - 2,176 10,212 (12,388)
Total $ 000 902 196 1,098 (5,500) (6,196) (11,696) (5) - (11,701) 23,176 2,707 25,883 25,244 (14,592) 10,652 25 (279) (44) (230) (528) (12,357) (9,036) 16,432
Eliminations / Unallocated $ 000 - - - (518) - 25 (165) (43) (201) (384) (7,806) (27) (1,701)
3.
SEGMENT REPORTING (continued)
Continuing Operations Business segment
Agenix (Shanghai)
Monoclonal
Bio-pharma-
antibody
Molecular
ceuticals
development
biology
$ 000
$ 000
$ 000
For the year ended 30 June 2007 Revenue Segment revenue
-
807
95
Unallocated revenue Total consolidated revenue Result Segment result
(151)
(5,394)
45
Unallocated expenses Consolidated profit / (loss) before tax Minority interest
(5)
-
-
Income tax (expense) benefit Consolidated profit / (loss) after tax Assets and liabilities Segment assets
21,236
1,906
552
Unallocated assets Total consolidated assets Segment liabilities
21,355
3,877
12
Unallocated liabilities Total consolidated liabilities Other segment information Acquisitions of property, plant and equipment, -
-
-
intangible assets and other non-current assets
(4)
(108)
(2)
Depreciation
-
(1)
-
Amortisation
Non-cash income (expenses) other than -
(29)
-
depreciation and amortisation
(4)
(138)
(2)
Non cash expenses
Cash flow information Net cash flow from operating activities
(152)
(4,454)
55
Net cash flow from investing activities
(9,009)
-
-
Net cash flow from financing activities
13,734
4,454
(55)

54

AGENIX LIMITED ANNUAL REPORT 2007

Total Operations Consolidated Total $ 000 17,837 87 17,924 379 (4,100) (4,100) (3,721) - (3,721) 18,194 5,460 5,460 23,654 3,681 5,762 5,762 9,443 258 (601) (541) 3,608 3,608 2,724 (8,483) 8,372 6,800
Total $ 000 17,091 - 17,091 10,493 - 10,493 - 10,493 13,313 - 13,313 2,167 - 2,167 197 (352) (507) 3,733 3,071 4,077 8,587 (12,664)
Discontinued Operations Pharma-
Industrial
Eliminations /
ceuticals
Biosystems
Unallocated
$ 000
$ 000
$ 000
-
36
-
134
91
-
-
-
-
164
-
-
-
-
-
-
(5)
-
-
-
-
-
-
186
-
(5)
186
(316)
36
-
1,754
211
-
(1,438)
(247)
-
Medical diagnostics $ 000 17,055 10,268 13,313 2,003 197 (347) (507) 3,547 2,890 4,357 6,622 (10,979)
Total $ 000 746 87 833 (10,114) (4,100) (14,214) - (14,214) 4,881 5,460 10,341 1,514 5,762 7,276 61 (249) (34) (125) (347) (12,560) (215) 19,464
Eliminations / Unallocated $ 000 - - (463) (5,440) 22 (19) (20) (234) (251) (4,330) 3,504 6,800
Continuing Operations Monoclonal antibody
Molecular
development
biology
$ 000
$ 000
498
248
(10,210)
96
4,835
509
6,940
14
39
-
(228)
(2)
(14)
-
109
-
(94)
(2)
(8,393)
163
(3,719)
-
12,827
(163)
3.
SEGMENT REPORTING (continued)
Business segment
Agenix (Shanghai)
Bio-pharma- ceuticals $ 000 For the year ended 30 June 2006 Revenue Segment revenue
-
Unallocated revenue Total consolidated revenue Result Segment result
-
Unallocated expenses Consolidated profit / (loss) before tax Income tax (expense) benefit Consolidated profit / (loss) after tax Assets and liabilities Segment Assets
-
Unallocated assets Total consolidated assets Segment liabilities
-
Unallocated liabilities Total consolidated liabilities Other segment information Acquisitions of property, plant and equipment, -
intangible assets and other non-current assets
-
Depreciation
-
Amortisation
Non-cash income (expenses) other than -
depreciation and amortisation
-
Non cash expenses
Cash flow information Net cash flow from operating activities
-
Net cash flow from investing activities
-
Net cash flow from financing activities
-

55

AGENIX LIMITED ANNUAL REPORT 2007

Total Operations Consolidated Total $ 000 9,775 33,803 25 Total Operations Consolidated Total $ 000 17,924 23,654 258
Total $ 000 8,677 7,920 - Total $ 000 17,091 13,313 197
Australia and New Zealand $ 000 16,521 7,920 - Australia and New Zealand $ 000 4,105 13,313 197
3.
SEGMENT REPORTING (continued)
Secondary segment – geographical Geographically, the group predominately generates revenue from markets in North America, Europe, Asia and Australia and New Zealand. Continuing operations (i)
Monoclonal antibody development
Revenues are generated from the Australian market.
(ii)
Molecular biology
Revenues are generated from the Australian market.
(iii)
Agenix (Shanghai) Bio-pharmaceuticals
Revenues will be generated from the Asian market.
Discontinued operations - see note 6 for more detail. (i)
Medical diagnostics
Revenues are generated from all the above mentioned markets.
Discontinuing Operations
Continuing Operations
Geographical segment
Australia and
North
Asia
For the year ended 30 June 2007
China
New Zealand
Total
America
Europe
Pacific
$ 000
$ 000
$ 000
$ 000
$ 000
$ 000
Segment revenue
-
1,098
1,098
(3,988)
(2,031)
(1,825)
Segment assets
21,236
4,647
25,883
-
-
-
Capital expenditure
-
25
25
-
-
-
Discontinuing Operations
Continuing Operations
Geographical segment
Australia and
North
Asia
For the year ended 30 June 2006
China
New Zealand
Total
America
Europe
Pacific
$ 000
$ 000
$ 000
$ 000
$ 000
$ 000
Segment revenue
-
833
833
8,316
2,559
2,111
Segment assets
-
10,341
10,341
-
-
-
Capital expenditure
-
61
61
-
-
-

56 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

4. REVENUE AND EXPENSES

CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Note 4. Revenues and expenses
Revenue and Expenses from Continuing Operations
**(a) ** Revenue
Revenue from the sale of goods 95 248 - -
Clinical trial services revenue 194 234 - -
Contract development services revenue 47 78 - -
Finance revenue 762 273 196 87
1,098 833 196 87
Breakdown of finance revenue:
Interest received - bank interest 309 140 169 87
Interest received - related parties 36 - 27 -
Interest received - change in NPV of milestone receipts 287 - - -
Net realised foreign exchange gains 104 24 - -
Net unrealised foreign exchange gains 26 109 - -
762 273 196 87
**(b) ** Other income
Net gains on disposal of non-current assets - 14 - -
Grants and development funding - 366 - -
Other revenue 6 1 6 -
6 381 6 -
**(c) ** Research and development costs
Research and development costs
®
ThromboView (5,152) (10,187) (32) 14
Other (152) (211) 3 (12)
(5,304) (10,398) (29) 2
**(d) ** Finance costs
Bank loans (60) (735) (52) (734)
Net realised foreign exchange losses (187) - - -
Net unrealised foreign exchange losses (1,131) - (655) -
(1,378) (735) (707) (734)
**(e) ** Depreciation and amortisation
Depreciation of non-current assets (279) (249) (38) (31)
Amortisation of non-current assets (44) (34) (27) (20)
(323) (283) (65) (51)
**(f) ** Employee benefit expense
Wages and salaries (2,191) (2,298) (1,212) (1,036)
Workers compensation costs (15) (21) (8) (15)
Long service leave provision (23) (11) (8) 3
Share-based payments expense (230) (469) (230) (469)
Corporate restructure - redundancies (62) (38) (62) (38)
Executive termination payments (78) (662) (78) (662)
~~Write-back of executive share-based payments expense~~ - 215 - 215
(2,599) (3,284) (1,598) (2,002)
**(g) ** Significant items
Executive termination payments (78) (662) (78) (662)
Write-back of executive share-based payments expense - 215 - 215
(78) (447) (78) (447)

57

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED

N OTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

4. REVENUE AND EXPENSES (continued)

CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Note 4. Revenues and expenses (continued)
Revenue and Expenses from Discontinued Operations
(h) Revenues from discontinued operations (note 6)
Revenue from the sale of goods 8,677 16,599 - -
Revenue from royalties and licences - 448 - -
Rental revenue - 44 - -
8,677 17,091 - -
Other income
Write-back of surplus lease space 260 - 260 -
Other revenue 25 6 - -
285 6 260 -
**(i) ** Expenses from discontinued operations (note 6)
Cost of sales (5,997) (6,533) (44) 68
Marketing expenses (603) (1,920) (41) 99
Occupancy and administration expenses (622) (1,330) (12) 41
Research and development - (521) - (21)
Restructure costs (306) (272) - -
Amortisation of patents, licences and brand names - (251) - -
Surplus lease space - (281) - (281)
Other expenses (178) (116) - -
(7,706) (11,224) (97) (94)
**(j) ** Depreciation and amortisation
Depreciation - (352) - -
Amortisation
Patents, licences and brand names - (251) - -
Directors' valuation - buildings - (254) - -
Other - (2) - -
- (859) - -
**(k) ** Employee benefit expense
Wages and salaries (1,907) (3,643) - -
Workers compensation costs (10) (17) - -
Long service leave provision (29) (29) - -
Share-based payments expense (97) 186 (97) 186
Restructure costs (306) (272) - -
(2,349) (3,775) (97) 186

58

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED

NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

5. INCOME TAX

INCOME TAX
CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
The prima facie tax, using tax rates applicable in the
country of operation, on loss and extraordinary items
differs from the income tax provided in the financial
statements as follows:
Loss before tax from continuing operations (11,701) (14,214) (14,227) (14,285)
Profit/(Loss) before tax from discontinued operations 6,923 10,493 (115) (4,388)
Loss before tax (4,778) (3,721) (14,342) (18,673)
Tax on loss before income tax at Group's statutory tax rate of 30%
(2006:30%) (1,433) (1,116) (4,303) (5,602)
Tax effect of permanent differences
Amortisation of intangibles - 152 - -
Share based payments expense 337 26 327 26
Write-down of related party receivables - - - 1,312
Impairment of financial assets - investment in subsidary - - - 3,056
(Profit) / loss on disposal of discontinued operations (1,700) (1,310) - -
Research and development concession (222) (740) - -
Other (net) - 8 - 3
Future income tax benefits arising from tax losses of - - - -
current year not brought to account 3,018 2,980 - 3,976 1,205
- - - -
Income tax expense reported in the consolidated income statement - - - -
Income tax expense attributed to discontinued operations - - - -
- - - -

The Group has tax losses arising in Australia of $38,263,621. In March 2007 an amendment was lodged with the Australia Taxation Office for R&D tax concessions relating to the 2006 financial year. The Group tax losses for the year ended 30 June 2006, taking into account this amendment, were $30,033,333. These losses may not be available to offset against future taxable profits of the companies in which the losses arose, due to the recent change in ownership structure. The Company is currently seeking advice from its taxation advisers in this regard.

At 30 June 2007 there is no recognised or unrecognised deferred income tax liability (2006: $nil) for taxes that would be payable on the unremitted earnings of certain of the Group’s subsidiaries, as the Group has no liability for additional taxation should such amount be remitted.

Tax Consolidation

The Company and its wholly owned Australian resident subsidiary companies have formed a consolidated tax group with effect from 1 April 2004 and are therefore taxed as a single entity from that date. The head Company of the consolidated tax group is Agenix Limited.

The members of the consolidated tax group have entered into a tax funding agreement and a tax sharing agreement with the head Company. Under the terms of the tax funding agreement, Agenix Limited and each of the companies in the consolidated tax group has agreed to pay a tax equivalent payment to or from the head Company, based on the current tax liability or current tax asset of the Company. Such amounts are reflected in amounts receivable from or payable to other members of the consolidated tax group.

The tax sharing agreement entered into between members of the consolidated tax group provides for the determination of the allocation of income tax liabilities between the companies should the head Company default on its tax payment obligations. No amounts have been recognised in the financial statements in respect of this agreement as payment under the tax sharing agreement is considered remote.

59

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

6. DISCONTINUED OPERATIONS

(a) Medical Diagnostics – Agen Biomedical

  • Animal Health in vitro diagnostic business

The Company has disposed of its Animal Health business.

The Animal Health in vitro diagnostic operations is reported under “Medical diagnostics”.

  • Human Health in vitro diagnostic business

The Company has disposed of Human Health business. The disposal is inline with the Company’s long-term focus and strategy.

The Human Health in vitro diagnostic operations is reported under “Medical diagnostics”.

(b) Pharmaceuticals - Milton Pharmaceuticals

As previously announced and reported, the Milton Pharmaceuticals operations were discontinued from 28 February 2005.

Agenix has retained responsibility for the lease of the former Milton Pharmaceuticals office and warehouse in Carole Park, a suburb of Ipswich, Queensland.

An amount of $150,751 has been provided for in the financial statements, being equal to the present value of total expected outlays relating to the surplus space, as specified under the lease agreement, net of expected sub-lease rental revenue.

Income of $260,000 has been reported reflecting a write-back of previous remaining accruals.

The Milton Pharmaceuticals operations are reported under “Pharmaceuticals”.

(c) Industrial Biosystems Pty Ltd

Agenix sold its non-core subsidiary, Industrial Biosystems Pty Ltd in March 2006 for $376,000. The Company’s sole asset, a land and building situated in Belmont Western Australia, had in past years supported research and development activities but more recently had been leased as a commercial property. An amount of $211,000 was received prior to 30 June 2006, with the final balance of $165,000 received on 6 July 2006.

60

AGENIX LIMITED ANNUAL REPORT 2007

6.
DISCONTINUED OPERATIONS (Continued)
Medical
diagnostics
Pharma-
ceuticals
Industrial
Biosystems
Total
Medical
diagnostics
Pharma-
ceuticals
Industrial
Biosystems
Total
$ 000
$ 000
$ 000
$ 000
$ 000
$ 000
$ 000
$ 000
CONSOLIDATED
2006
CONSOLIDATED
2007
Revenues (note 4(h))
8,677
-
-
8,677
17,055
-
36
17,091
Other income
25
260
-
285
6
-
-
6
Expenses (note 4(i))
(7,706)
-
-
(7,706)
(11,252)
34
(6)
(11,224)
(d) Financial performance information
Gross profit / (loss)
996
260
-
1,256
5,809
34
30
5,873
Profit / (loss) on disposal from discontinued operations
5,667
-
-
5,667
4,459
100
61
4,620
Profit / (loss) before tax on discontinued operations
6,663
260
-
6,923
10,268
134
91
10,493
Income tax (expense)/benefit from discontinued operations
-
-
-
-
-
-
-
-
6,663
260
-
6,923
10,268
134
91
10,493
Profit/(loss) after income tax (expense)/benefit from discontinued operations
(e) Asset disposals and liabilities to be settled
Assets
Current receivables
4,235
8
-
4,243
4,006
-
-
4,006
Non-current receivables
772
-
-
772
-
-
-
-
Inventories
734
-
-
734
1,950
-
-
1,950
Property, plant and equipment held for disposal
335
-
-
335
5,521
-
-
5,521
Intangibles
1,836
-
-
1,836
1,836
-
-
1,836
The carrying amounts of total assets to be disposed of and liabilities to
be settled of as at 30 June 2007 are as follows:
Total assets
7,912
-
-
7,920
13,313
-
-
13,313
Liabilities
Trade and other payables
2,876
134
-
3,010
1,770
23
-
1,793
Provisions
389
-
-
389
374
-
-
374
Total liabilities
3,265
134
-
3,399
2,144
23
-
2,167
Net assets
4,647
(134)
-
4,521
11,169
(23)
-
11,146
(f) Operation cash flows during the year
Net operating cash flows
2,176
(399)
-
1,777
4,357
(316)
36
4,077
Net investing cash flows
10,212
-
165
10,377
6,622
1,754
211
8,587
Net financing cash flows
(12,388)
399
(165)
(12,154)
(10,979)
(1,438)
(247)
(12,664)
Net cash inflows/(outflows)
-
-
-
-
-
-
-
-

61

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

7. LOSS PER SHARE

Basic earnings per share amounts are calculated by dividing net profit/(loss) for the year attributable to ordinary equity holders of the parent by the weighted average number of ordinary shares outstanding during the year.

Diluted earnings per share amounts are calculated by dividing the net profit/(loss) attributable to ordinary equity holders of the parent by the weighted average number of ordinary shares outstanding during the year plus the weighted average number of ordinary shares that would be issued on the conversion of all of the dilutive potential ordinary shares into ordinary shares (i.e. options).

Options granted are considered to be potential ordinary shares and have been taken into account in the determination of diluted earnings per share. As the group has incurred losses during the year, the options are not dilutive and therefore not used in the calculation of diluted earnings per share. These options could potentially dilute basic earnings per share in the future.

The following reflects the income and share data used in the basic and diluted earnings per share computations:

CONSOLIDATED
2007 2006
$ 000 $ 000
The following reflects the income and share data used in the
calculations of basic and diluted earnings per share
Net loss (4,778) (3,721)
CONSOLIDATED
2007 2006
Number of Shares Number of Shares
Weighted average number of ordinary shares used in
calculating basic and diluted earnings per share 228,647,333 188,833,432

There have been no transactions involving ordinary shares between the reporting date and the date of completion of these financial statements.

Effective 21 July 2007 2,600,000 unlisted employee options were issued to employees with an exercise price of $0.24, expiring 21 July 2013. A further 2,880,000 unlisted options were issued to key executives with an exercise price of $0.24, expiring on 21 July 2009.

To calculate earnings per share amounts for the discontinued operations, the weighted average number of ordinary shares for both basic and diluted amounts is as per table above. The following table provides profit (loss) figure used as numerator:

2007 2006
$ 000 $ 000
Net profit attributable to ordinary equity holders
of the parent from discontinued operations (Note 6): 6,923 10,493

8. DIVIDENDS PAID AND PROPOSED

No dividend has been paid or proposed by the Company in relation to the year ended 30 June 2007 (2006: $nil).

CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Franking credit balance
Franking credits available for the subsequent financial year
calculated on tax paid basis - - 539 539

62 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTSNOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007For the year ended 30 June 2007

9. CASH AND CASH EQUIVALENTS

Cash at bank earns interest at floating rates based on daily bank deposit rates.

CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Cash at bank 3,782 354 2,444 146
Deposits at call - 8,389 - 5,830
3,782 8,743 2,444 5,976

The fair value of cash and cash equivalents is $3,782,000 (2006: $8,743,000).

Reconciliation to Cash Flow Statement

CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Reconciliation of the net loss after tax to the net cash
flows from operations
Net loss (4,778) (3,721) (14,342) (18,673)
Non-cash items
~~Depreciation of non-current assets~~ ~~279~~ ~~601~~ ~~38~~ (31)
Amortisation of non-current assets 44 541 27 (20)
Share based payments expense 327 88 327 88
Intercompany charges - - - -
Write-off of tax credit 418 - 418 -
Loss on forward contracts 654 - 654 -
Write-down of non-current assets 43 - - 4,351
Impairment of financial assets - investment in subsidary - - 8,049 10,186
~~Losses (profits) on sale of property, plant and equipment~~ ~~-~~ ~~(14)~~ ~~-~~ -
Profit on disposal of discontinued operations (5,667) (4,620) - -
Change in NPV of Milestone receivables - - - -
Net foreign currency (gains) losses 1,131 (133) - -
Other (562) 116 - (37)
Changes in assets and liabilities
Decrease (increase) in receivables (136) (1,233) (340) (186)
Decrease (increase) in prepayments and other current assets (73) 160 (55) 112
Decrease (increase) in inventories (4) 494 - -
(Decrease) increase in payables (2,833) (468) 812 (231)
(Decrease) increase in provisions (343) (294) (250) 111
Decrease increase in assets/liabilities held for sale 920 - - -
Net cash provided by (used in) operating activities (10,580) (8,483) (4,662) (4,330)

Disclosure of financing facilities Refer to Note 19 and 23.

63

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

10. TRADE AND OTHER RECEIVABLES (CURRENT)

Terms and conditions relating to the above financial instruments

CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
Notes $ 000 $ 000 $ 000 $ 000
Trade debtors (i) 713 729 14 183
Provision for doubtful debts - - - -
713 729 14 183
Sundry debtors 151 24 575 13
Amounts receivable from controlled entities (ii) - - 9,287 770
Australian Taxation Office 130 35 119 7
994 788 9,995 973

(i) Trade receivables are non-interest bearing and generally are on 30-60 day terms. An allowance for doubtful debts is made when there is objective evidence that a trade receivable amount is impaired.

(ii) Amounts payable to Agenix Limited from controlled entity at call.

(iii) For terms and conditions relating to related party receivables refer to Note 26.

Details regarding the effective interest rate and credit risk of current receivables are disclosed in Note 23.

11. INVENTORIES

INVENTORIES
CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Raw materials and stores
At cost 4 - - -
Provision for diminution in value - - - -
4 - - -
Work-in-progress
At cost - - - -
Provision for diminution in value - - - -
- - - -
Finished goods
At cost - - - -
Provision for diminution in value - - - -
- - - -
Total inventories at lower of cost and net realisable value 4 - - -
At 30 June 2007, inventories in Medical Diagnostics were classified as assets held for sale (Note 6).
RECEIVABLES (NON-CURRENT)
CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 **$ ** 000
Wholly-owned group receivables 46 - - -
46 - - -

12. RECEIVABLES (NON-CURRENT)

(a) Details of terms and conditions of related party receivables are set out in Note 26.

13. SHARES IN CONTROLLED ENTITIES

SHARES IN CONTROLLED ENTITIES
CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Investment in controlled entities at cost (note 26(a)) - - 11,882 26,846
Accumlative impairment losses - - (8,049) (15,036)
- - 3,833 11,810

64

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMAGENIX LIMITEDTED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

14. PROPERTY, PLANT AND EQUIPMENT

CONSOLIDATED PARENT
Construction in Freehold land Plant and Freehold land Plant and
progress and buildings Equipment Total and buildings Equipment Total
$ 000 $ 000 $ 000 $ 000 $ 000 $ 000 $ 000
Year ended 30 June 2007
As at 1 July 2006, net of accumulated
depreciation and amortisation - - 572 572 - 74 74
Additions - - 25 25 - 16 16
Acquisition of subsidiary 4,631 - 537 5,168 - - -
Disposals - - (2) (2) - - -
Transferred from assets held for sale - - 141 141 - (1) (1)
Asset written-down to nil - - (21) (21) - - -
Depreciation - - (279) (279) - (38) (38)
Amortisation - - - - - - -
~~Foreign currency translation difference~~ ~~(65)~~ ~~-~~ ~~(10)~~ ~~(75)~~ ~~-~~ ~~-~~ -
At 30 June 2007, net of accumulated
depreciation and amortisation 4,566 - 963 5,529 - 51 51
At 1 July 2006
At cost - opening balance - - 1,609 1,609 - 183 183
Accumulated depreciation - - (1,037) (1,037) - (109) (109)
At directors' valuation deemed cost - - - - - - -
Accumulated amortisation - - - - - - -
Net carrying amount - - 572 572 - 74 74
~~At 30 June 2007~~
At cost 4,566 - 2,279 6,845 - 196 196
Accumulated depreciation - - (1,316) (1,316) - (145) (145)
Net carrying amount 4,566 - 963 5,529 - 51 51
CONSOLIDATED PARENT
Freehold land Plant and Freehold land Plant and
and buildings Equipment Total and buildings Equipment Total
$ 000 $ 000 $ 000 $ 000 $ 000 $ 000
Year ended 30 June 2006
As at 1 July 2005, net of accumulated
depreciation and amortisation 4,978 1,807 6,785 - 120 120
Additions 46 212 258 - 22 22
Disposals - (95) (95) - (38) (38)
Transferred to assets held for sale (4,641) (880) (5,521) - - -
Depreciation (129) (472) (601) - (30) (30)
Amortisation (254) - (254) - - -
At 30 June 2006, net of accumulated
depreciation and amortisation - 572 572 - 74 74
At 1 July 2005
At cost - opening balance 6,890 4,548 11,438 - 221 221
Accumulated depreciation (3,400) (2,741) (6,141) - (101) (101)
At directors' valuation deemed cost 2,492 - 2,492 - - -
Accumulated amortisation (1,004) - (1,004) - - -
Net carrying amount 4,978 1,807 6,785 - 120 120
At 30 June 2006
At cost - 1,609 1,609 - 183 183
Accumulated depreciation - (1,037) (1,037) - (109) (109)
Net carryingamount - 572 572 - 74 74

The useful life of the assets was estimated as follows both for 2007 and 2006:

Buildings – over 40 to 50 years Plant and equipment – over 3 to 20 years

65

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED

NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

15. INTANGIBLE ASSETS

15. INTANGIBLE ASSETS
CONSOLIDATED PARENT
Brand names at Intellectual Patents and Brand names at Intellectual Patents and
cost Property licences Software Total cost Property licences Software Total
$ 000 $ 000 $ 000 $ 000 $ 000 $ 000 $ 000 $ 000
As at 1 July 2006
Cost (gross carrying amount) - - - 423 423 - - - 115 115
Accumulated amortisation - - - (322) (322) - - - (45) (45)
Net carryingamount - - - 101 101 - - - 70 70
Year ended 30 June 2007
At 1 July 2006, net of accumulated amortisation - - - 101 101 - - - 70 70
Additions - - - - - - - - -
Acquisition of subsidiary (note 24) - 15,182 - - 15,182 - - - - -
Transferred to assets held for sale - - - - - - - - - -
Disposals - - - (1) (1) - - - - -
Asset written-down to nil - - - (8) (8) - - - - -
Amortisation - - (44) (44) - - - (27) (27)
Foreign currency translation difference - (128) - - (128)
At 30 June 2007,net of accumulated amortisation - 15,054 - 48 15,102 - - - 43 43
At 30 June 2007
Cost (gross carrying amount) - 15,054 - 414 15,468 - - - 115 115
Accumulated amortisation - - - (366) (366) - - - (72) (72)
Net carryingamount - 15,054 - 48 15,102 - - - 43 43
CONSOLIDATED CONSOLIDATED PARENT PARENT
Brand names at Intellectual Patents and Brand names at Intellectual Patents and
cost Property licences Software Total cost Property licences Software Total
$ 000 $ 000 $ 000 $ 000 $ 000 $ 000 $ 000 $ 000
As at 1 July 2005
Cost (gross carrying amount) 3,428 - 1,868 410 5,706 - - - 117 117
Accumulated amortisation and impairment - - (478) (288) (766) - - - (25) (25)
Net carryingamount 3,428 - 1,390 122 4,940 - - - 92 92
Year ended 30 June 2006
At 1 July 2005, net of accumulated amortisation 3,428 - 1,390 122 4,940 - - - 92 92
Additions - - - 17 17 - - - - -
Transferred to assets held for sale (1,836) - - - (1,836) - - - -
Disposals (1,592) - (1,139) (4) (2,735) - - - (2) (2)
Amortisation - - (251) (34) (285) - - - (20) (20)
At 30 June 2006,net of accumulated amortisation - - - 101 101 - - 70 70
At 30 June 2006
Cost (gross carrying amount) - - - 423 423 - - - 115 115
Accumulated amortisation and impairment - - - (322) (322) - - - (45) (45)
Net carryingamount - - - 101 101 - - - 70 70

The excess of Consideration paid for SHRG and the Company’s stake in YSY over the net fair value of net tangible assets acquired, represents the inherent intellectual property. Refer to note 24 for further details.

Software has been determined to have a finite life and is amortised using the straight line method over a period of 3 to 5 years. If an impairment indication arises, the recoverable amount is estimated and the expense is taken to the income statement.

No impairment loss was recognised for the 2007 financial year.

66 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

16. SHARE-BASED PAYMENT PLANS

Employee option plan

An employee option plan was approved by the shareholders on 8 June 2001. Under the plan all Directors, executives and staff of the Consolidated Entity are eligible to be issued with options over the ordinary shares of Agenix Limited. Options are issued to all full-time and part-time employees at the discretion of the Board at an exercise price calculated as the average closing price for the twenty trading days prior to the grant date. The options are issued for a maximum term of six years and have a maximum vesting period of two years from date of grant. Employees forfeit their options if they cease employment with the Company prior to the options vesting. The options cannot be transferred and are not quoted on the Australian Securities Exchange. Option holders do not participate in any share issue of the Company or any other body corporate. They have no voting powers.

The expense recognised in the income statement in relation to share-based payments is disclosed in note 4(f) and note 4(k).

The following table illustrates the number (No.) and weighted average exercise price (WAEP) of and movements in share options during the year:

Notes
No.
WAEP
$
2007
No.
WAEP
$
2006
Balance at the beginning of the year
1
7,844,450
0.4307
Granted
21,116,250
0.4786
Forfeited
(2,152,500)
0.4144
Exercised
-
-
13,308,225
0.4752
2,578,750
0.2928
(8,042,525)
0.4483
-
-
Balance at the end of the year
2
26,808,200
0.4700
7,844,450
0.4307

Exercisable at the end of theyear
4,509,950
0.4750
3,173,950
0.3621
Notes:
1 See table 16(a)
2 See table 16(b)

During the financial year, no employees or consultants exercised options to acquire fully paid ordinary shares in Agenix Limited.

The average remaining contractual life for the share options outstanding as at 30 June 2007 is between 1 and 6 years (2006: 1 and 6 years).

The range of exercise price for options outstanding granted during the year was $0.2200 -$0.7000 (2006: $0.2928-$0.7028).

The weighted average fair value of options granted during the year was $0.4801 as valued by the Black-Scholes option pricing model.

(a) Options held at the beginning of the reporting period:

The following table summarises information about options held by employees as at 1 July 2006:

Number WAEP
of options Grant date Vesting date Expiry date $
1,230,200 20 July 2001 19 July 2003 20 July 2007 0.3228
607,500 14 March 2003 25 July 2004 25 July 2008 0.3328
1,306,250 6 October 2003 21 July 2005 21 July 2009 0.4128
30,000 1 February 2004 31 January 2006 31 January 2010 0.7028
1,418,000 21 September 2004 21 July 2006 21 July 2010 0.6728
1,250,000 18 November 2004 18 November 2006 18 November 2010 0.5428
2,002,500 31 August 2005 21 July 2007 21 July 2011 0.2928
7,844,450

67

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITEDAGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTSNOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007For the year ended 30 June 2007

16. SHARE-BASED PAYMENT PLANS (continued)

(b) Options held at the end of the reporting period:

The following table summarises information about options held by employees as at 30 June 2007:

Number of options
Grant date
Vesting date
Expiry date
WAEP
$
Number of options
Grant date
Vesting date
Expiry date
WAEP
$
1,014,200
20 July 2001
19 July 2003
20 July 2007
0.3228
457,500
14 March 2003
25 July 2004
25 July 2008
0.3328
842,500
6 October 2003
21 July 2005
21 July 2009
0.4128
945,750
21 September 2004
21 July 2006
21 July 2010
0.6728
1,250,000
18 November 2004
18 November 2006
18 November 2010
0.5428
1,328,250
31 August 2005
21 July 2007
21 July 2011
0.2928
1,470,000
31 August 2006
21 July 2008
21 July 2012
0.2200
500,000
21 November 2006
21 July 2008
21 July 2012
0.2500
3,000,000
21 November 2006
15 December 2007
15 December 2011
0.5300
1,000,000
21 November 2006
15 December 2008
15 December 2011
0.5300
3,000,000
6 June 2007
18 April 2010
17 April 2013
0.3000
3,000,000
6 June 2007
18 April 2010
17 April 2013
0.4000
3,000,000
6 June 2007
18 April 2010
17 April 2013
0.5000
~~3000000~~
~~6 June 2007~~
~~18 April 2010~~
~~17 April 2013~~
~~06000~~
~~,,~~




~~.~~
3,000,000
6 June 2007
18 April 2010
17 April 2013
0.7000
26,808,200

The following table lists the inputs to the model used for the years ended 30 June 2006 and 30 June 2007:

O22 O21B O21A O20 O19 O18 O17 O16 O13 O10 OP 8
Dividend yield (%) - - - - - - - - - - -
Expected Volatility (%) 48.90% 51.49% 49.61% 49.61% 47.1% 47.9% 48.1% 48.7% 47.3% 49.6% 44.4%
Risk-free interest rate (%) 5.80% 6.00% 5.80% 5.80% 5.30% 5.20% 5.60% 5.90% 5.90% 5.90% 5.40%
Expected life of options (years) 5.41 2.00 4.82 5.64 5.75 5.64 5.75 5.60 5.75 5.54 5.12
Option exercise price ($) 0.2400 0.5300 0.5300 0.2200 0.4000 0.2928 0.5428 0.6728 0.7028 0.4128 0.3328
Weighted average share price at grant date ($) 0.25 0.55 0.55 0.22 0.26 0.30 0.64 0.55 0.71 0.69 0.29

The expected life of the options is based on historical data and is not necessarily indicative of exercise patterns that may occur. The expected volatility reflects the assumption that the historical volatility is indicative of future trends, which may also not necessarily be the actual outcome. No other features of options granted were incorporated into the measurement of fair value.

The fair value of options is measured using the Black-Scholes option pricing model taking into account the terms and conditions upon which the instrument was granted.

Subsequent to year end the following options were granted:

Effective 21 July 2007 2,600,000 options were issued to employees pursuant to the Company’s annual option grant policy. These options have a vesting period of 2 years, an exercise price of $0.24 and expire on 21[st] July 2013. As part of remuneration for additional duties performed for the Company, the Company intends to issue 125,000 options to Mr Karl Schlobohm (a Non-Executive Director) on the same terms and conditions as outlined, but subject to shareholder approval.

Also effective 21 July 2007 the Board of Directors issued 2,880,000 “short-term” options to employees as a “one-off’ exercise to provide incentive to Company management due to the significant difference between the historical option prices and the recent share price performance. These options were issued with an exercise price of $0.24, vest immediately, and expire after 24 months. The Company also intends to issue 3,120,000 opti ~~ons to Mr Neil Leggett (CEO and Managing Director) on the same terms and conditions as outlined, but subject to shareholder approval.~~

(c) Options issued to consultants:

(c) Options issued to consultants:
N WAEP
umber of options
Grant date
Vesting date
Expiry date
$
250,000
27 December 2002
22 September 2004
22 September 2009
0.4000
200,000
1 January2006
1 January2006
1 January2012
0.4000
450,000

68

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

17. TRADE AND OTHER PAYABLES (CURRENT)

CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Trade creditors 1,402 1,288 319 181
Amounts payable to controlled entities - - 7,318 2,088
Other creditors 2,855 329 745 71
Loans to related parties 364 - - -
4,621 1,617 8,382 2,340

(a) Terms and conditions relating to the above financial instruments

(i) Trade creditors are non-interest bearing and are normally settled on 7 to 60 day terms.

(ii) Amounts payable from Agenix Limited to controlled entities are at call.

(iii) Other creditors in the nature of accounting accruals, are non-interest bearing and have a an average term of 6 months.

(iv) Related party payables relate to amounts owing to ex-shareholders of SHRG, these amounts are interest free and payable on demand.

Information regarding the effective interest rate and credit risk of current payables is set out in note 23.

18. DERIVATIVE FINANCIAL INSTRUMENTS

CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Current liabilities
Forward currency contracts 654 - 654 -
654 - 654 -

USD forward foreign exchange contracts were taken out to reduce the Company’s exposure to fluctuations in foreign exchange rates for contracted cashflows related to the China acquisition. These contracts are fair valued by comparing the contract rate to the market rates with the same length of maturity. All movements in fair value are recognised in profit or loss in the period they occur.

At balance date, the Consolidated Entity had five (5) outstanding forward contracts to buy United States dollars (USD) and sell Australian dollars (AUD) for a total value of USD 6,325,000 settling in 30 days at an average exchange rate of AUD/USD 0.7831. The hedge is not considered to have the level of specificity required to classify it as a specific hedge.

69

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

19. INTEREST AND NON-INTEREST BEARING LOANS AND BORROWINGS

CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
(a) Current
Commercial bill facility - 4,976 - 4,976
Interest bearing liabilities (i) 666 - - -
Non-interest bearingloans 2,262 - - -
2,928 4,976 - 4,976
(b) Non-current
Commercial bill facility - - - -
Interest bearingloans(i) 2,063 - - -
2,063 - - -
(c) Financing facilities available
At the reporting date the following financing facilities had
been negotiated and were available
Total facilities:
commercial bills - 5,000 - 5,000
Facilities used at reporting date:
commercial bills - 5,000 - 5,000
Facilities unused at reporting date:
commercial bills - - - -
(d) Assets pledged as security
Current
Floating charge
Cash and cash equivalents - 8,743 - 5,976
Receivables - 788 - 973
- 9,531 - 6,949
Non-current
First mortgage
Property, plant and equipment - 572 - 74
Available for sale assets - 13,313 8 -
- 13,885 8 74
Total assets pledged as security - 23,416 8 7,023

(i). SHRG has a restructuring loan payable to a Chinese development company. The Chinese management team are conducting discussions with the lenders in relation a repayment schedule, however no agreement on terms has been finalised.

70

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITEDAGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTSNOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007For the year ended 30 June 2007

20. PROVISIONS

PROVISIONS
Items in
relation to Surplus leased
Milton Long service leave Annual leave space Total
$ 000 $ 000 $ 000 $ 000 $ 000
CONSOLIDATED
At 1 July 2006 31 144 146 362 683
Acquisition of subsidiary - - - - -
Expensed (credited ) to income statement 14 248 243 (152) 353
Utilised (45) - (85) (59) (189)
Transferred to liabilities held for sale(note 6) - (298) (163) - (461)
At 30 June 2007 - 94 141 151 386
Current 2007 - 51 141 58 250
Non-current 2007 - 43 - 93 136
- 94 141 151 386
Current 2006 31 112 146 53 342
Non-current 2006 - 32 - 309 341
31 144 146 362 683
Items in
relation to Surplus leased
Milton ~~Long service leave~~ ~~Annual leave~~ ~~space~~ Total
$ 000 $ 000 $ 000 $ 000 $ 000
~~PARENT~~
At 1 July 2006 31 52 57 362 502
Expensed (credited ) to income statement 14 8 61 (152) (69)
Utilised (45) (36) (41) (58) (180)
At 30 June 2007 - 24 77 152 253
Current 2007 - - 77 58 135
Non-current 2007 - 24 - 94 118
- 24 77 152 253
Current 2006 31 45 57 53 186
Non-current 2006 - 7 - 309 316
31 52 57 362 502

Surplus lease space

Agenix has retained responsibility for the lease of the former Milton Pharmaceuticals office and warehouse in Carole Park, a suburb of Ipswich, Queensland.

This provision recognised for the present value of total expected outlays relating to the surplus leased space, as specified under the lease agreement, net of expected sub-leased rental revenue.

71

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

21. CONTRIBUTED EQUITY AND RESERVES

CONTRIBUTED EQUITY AND RESERVES
CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
(a) Issued and paid up capital
Ordinary shares fully paid 64,811 50,114 64,811 50,114
Less: escrowed shares to SHRG Vendors (5,419) - (5,419) -
Total contributed equityattributable to members of the Company 59,392 50,114 59,392 50,114

(b) Terms and conditions of contributed equity Ordinary shares

Ordinary shares have the right to receive dividends as declared and, in the event of winding up the Company, to participate in the proceeds from the sale of all surplus assets in the proportion to the number of and amounts paid up on shares held.

Escrowed Shares

Ordinary fully-paid shares were issued to the SHRG Vendors on 17 April 2007. The shares have been funded by a non-cash loan by Agenix at an annual interest rate of 8% secured over the shares. Shares are escrowed 50% to 17 April 2008, 30% to 17 April 2009 and 20% to 17 April 2010. The shares will not be released from Escrow unless the shareholders warranties in the agreement for the SHRG aquisition are satisfied.

Escrowed Shares
Ordinary fully-paid shares were issued to the SHRG Vendors on 17 April 2007. The shares have been funded by a non-cash loan by Agenix at an annual
interest rate of 8% secured over the shares. Shares are escrowed 50% to 17 April 2008, 30% to 17 April 2009 and 20% to 17 April 2010. The shares will not
be released from Escrow unless the shareholders warranties in the agreement for the SHRG aquisition are satisfied.
Escrowed Shares
Ordinary fully-paid shares were issued to the SHRG Vendors on 17 April 2007. The shares have been funded by a non-cash loan by Agenix at an annual
interest rate of 8% secured over the shares. Shares are escrowed 50% to 17 April 2008, 30% to 17 April 2009 and 20% to 17 April 2010. The shares will not
be released from Escrow unless the shareholders warranties in the agreement for the SHRG aquisition are satisfied.
2007
2006
$'000
Number of Shares
$'000
Number of
Shares
(c) Movement in ordinary shares on issue
Balance at the beginning of the financial year
212,595,820
50,114
Issued during the year
- Employee options exercised during the year
-
-
- 1:4 non-renouncable entitlement offer
61,121,205
6,723
Cost of the non-renounceble entitlement offer
-
(550)
$3.5 million share placement
31,889,000
3,508
Cost of the share placement
-
(403)
157,567,565
37,664
-
-
41,391,891
10,348
-
(718)
13,636,364
3,000
-
(180)
Balance at the end of the financialyear
305,606,025
59,392
212,595,820
50,114

(d) Terms and conditions of share options

Options are offered to employees on an annual basis under the Employee Option Plan. Details of the plan can be found in note 16. Options are also issued to certain external consultants to the company.

Details of options granted to external consultants are as follows:

2007
2006
2007
2006
Expiry
Expiry
1/01/2012
22/09/2009
Number of 40c
Number of 40c
Options
Options
Expiry
Expiry
Expiry
1/01/2012
31/10/2010
22/09/2009
Number of 40c
Number of 71c
Number of 40c
Options
Options
Options
Share options
Balance at the beginning of the financial year
200,000
250,000
- granted
-
-
- forfeited
-
-
-exercised
-
-
-
30,000
250,000
200,000
-
-
(30,000)
-
-
-
-
Balance at the end of the financialyear
200,000
250,000
200,000
-
250,000

Options cannot be transferred and are not quoted on the Australian Securities Exchange. Option holders do not participate in any share issue or interest issue of the Company or any other body corporate. They have no voting powers.

72

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITEDAGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTSNOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007For the year ended 30 June 2007

21. CONTRIBUTED EQUITY AND RESERVES (continued)

CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
(e) Movement in accumulated losses
Balance at beginning of the financial year (39,375) (35,654) (42,628) (23,955)
Net loss attributable to members of Agenix Limited (4,773) (3,721) (14,342) (18,673)
Balance at end of the financial year (44,148) (39,375) (56,970) (42,628)
CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
(f) Share option reserves
At 1 July 3,472 3,384 3,472 3,384
Milestone payments (see note 24) 510 - 510 -
Share options issued as payments for SHRG (see note 24) 289 - 289 -
Share basedpayments 327 88 327 88
At 30 June 4,598 3,472 4,598 3,472
CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
(g) Movement in Minority interest
Balance at beginning of the financial year - - - -
Net loss attributable to MinorityInterest (5) - - -
Balance at end of the financial year (5) - - -

~~Nature and purpose of reserves~~

The share option reserve is used to record the fair value of options issued.

Share based payments

The share based payments expense line is used to record the value of options provided to employees and Directors as part of their remuneration. Refer to Note 16 for further details.

Milestone payments and share options issued for the acquisition of SHRG (refer to note 24)

The Milestone options and share options issued for the acquisition of SHRG have been valued using the Black-Scholes model, which takes into account factors including the option exercise price, the current level of volatility of the underlying share price, the risk free interest rate, expected dividends of the underlying share, current market price of the underlying share and expected life of the option. Refer to note 24 (a) for details of the option terms.

73

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

22. FINANCIAL RISK MANAGEMENT OBJECTIVES AND POLICIES

The Group’s principal financial instruments comprise the commercial facility, cash and short-term deposits. The main purpose of these financial instruments is to raise finances for the Group’s operations. The Group has various other financial assets and liabilities such as trade receivables and trade payables which arise directly from its operations. The main risks arising from the Group’s financial instruments are foreign currency risk, credit risk and liquidity risk.

Foreign currency risk

The Group has transactional currency exposures. Such exposures arise from sales and purchases in currencies other than the Group’s measurement currency particularly with the US dollar and the Chinese RMB. The Group manages this through the use of US dollar bank accounts as well as forward exchange contracts designed to hedge specified amounts for foreign currencies in the future at stipulated exchange rates. The objective in entering into the forward exchange contracts is to protect the Consolidated Entity against unfavourable exchange rate movements for both contracted and anticipated future sales and purchases undertaken in foreign currencies. The accounting policy in regards to forward exchange contracts is detailed in Note 2(e).

At balance date, the Consolidated Entity had five outstanding forward contracts to buy United States dollars (USD) and sell Australian dollars (AUD) for a total value of USD 6,325,000 settling in 30 days. The hedge is not considered to have the level of specificity required to classify it as a specific hedge.

Credit risk exposure

It is the Group’s policy that all customers who wish to trade on credit terms are subject to credit verification procedures.

Credit risk in trade receivables is managed in the following ways:

  • payment terms are 30 days for domestic customers and 60 days for international customers; and

  • a risk assessment process is used for customers with balances over $25,000.

Liquidity risk

The Group manages liquidity risk by maintaining adequate reserves, banking facilities and reserve borrowing facilities by continuously monitoring forecast and actual cash flows and matching the maturity profile of financial assets and liabilities.

23. FINANCIAL INSTRUMENTS

Net fair values

All financial assets and liabilities have been recognised at the balance date at their fair values.

The following methods and assumptions are used to determine the net fair values of financial assets and liabilities:

Recognised financial instruments

Cash, cash equivalents: The carrying amount approximates fair value because of the short term to maturity.

Trade receivables, trade creditors: The carrying amount approximates fair value because of the short term to maturity of the instruments.

Interest bearing loans and borrowings: The carrying amount approximates fair value because of the short term to maturity of the instruments.

Long-term interest bearing loans and borrowings: The fair values of long-term borrowings are estimated using discounted cash flow analysis, based on current incremental borrowing rates for similar types of borrowing arrangements.

Non-interest bearing loans (current): The carrying amount approximates fair value of the investments because of the short term to maturity.

Long-term non-interest bearing loans: The carrying amount approximates fair value of the investments because of the short term to maturity.

Forward exchange contracts: The fair values of forward exchange contracts is determined as the recognised gain or loss at Reporting date calculated by reference to current forward exchange rates for contracts with similar maturity profiles.

74 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

23. FINANCIAL INSTRUMENTS (continued)

Interest rate risks

The following table sets out the carrying amounts, by maturity, of the financial instruments exposed to interest rate risks:

Year ended 30 June 2007
Floating
interest rate
Total carrying
Weighted
amount as per
average
1 year
1 to
Non-interest
balance
effective
or less
5years
bearing
sheet
interest rate
MATURING IN:
FIXED INTEREST RATE
2007
2007
2007
2007
2007
2007
$ 000
$ 000
$ 000
$ 000
$ 000
%
CONSOLIDATED
Interest rate risk
Financial assets
Cash and deposits
3,781
-
-
1
3,782
5.61%

Trade and other receivables
-
-
-
994
994
N/A
Reveivables non-current
-
-
-
46
46
N/A
Total financial assets
3,781
-
-
1,041
4,822
Financial liabilities
Trade and sundry creditors
-
-
-
4,621
4,621
N/A
Derivative financial instruments
-
-
-
654
654
N/A
Interest bearing loans and borrowings (i)
-
666
-
-
666
12.00%
Non-interest bearing loans - Current
2,262
-
-
-
2,262
N/A
Interest bearing loans and borrowings non-curr
-
-
2,063
-
2,063
12.00%
Total financial liabilities
2,262
666
2,063
5,275
10,266
FIXED INTEREST RATE FIXED INTEREST RATE FIXED INTEREST RATE FIXED INTEREST RATE Total carrying Weighted
MATURING IN: amount as per average
Floating 1 year 1 to Non-interest balance effective
interest rate or less 5years bearing sheet interest rate
2007 2007 2007 2007 2007 2007
$ 000 $ 000 $ 000 $ 000 $ 000 %
PARENT
Interest rate risk
Financial assets
Cash and deposits 2,444 - - - 2,444 5.61%
Trade and other receivables - - - 9,995 9,995 N/A
Total financial assets 2,444 - - 9,995 12,439
Financial liabilities
Short term borrowings - - - - - N/A
Trade and sundry creditors - - - 8,382 8,382 N/A
Derivative financial statements - - - 654 654 N/A
Interest-bearing loans and borrowings - - - - - N/A
Non-interest bearing loans - current - - - - - N/A
Non-interest bearing loans-non-current - - - - - N/A
Total financial liabilities - - - 9,036 9,036

(i). This relates to an SHRG restructuring loan payable to a Chinese development company. The Chinese management team are conducting discussions with the lenders in relation to a repayment schedule, however no agreement has been met.

75

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED (ii). AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTSNOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007For the year ended 30 June 2007

23. FINANCIAL INSTRUMENTS (continued)

Year ended 30 June 2006 FIXED INTEREST RATE FIXED INTEREST RATE Total carrying Weighted
MATURING IN: amount as per average
Floating 1 year 1 to Non-interest balance effective
interest rate or less 5years bearing sheet interest rate
2006 2006 2006 2006 2006 2006
$ 000 $ 000 $ 000 $ 000 $ 000 %
CONSOLIDATED
Interest rate risk
Financial assets
Cash and deposits 8,742 - - 1 8,743 5.24%
Trade and other receivables - - - 788 788 N/A
Total financial assets 8,742 - - 789 9,531
Financial liabilities
Commercial bills 4,976 - - - 4,976 6.43%
Trade and sundry creditors - - - 1,617 1,617 N/A
Total financial liabilities 4,976 - - 1,617 6,593
FIXED INTEREST RATE FIXED INTEREST RATE FIXED INTEREST RATE FIXED INTEREST RATE Total carrying Weighted
MATURING IN: amount asper average
Floating 1 year 1 to Non-interest balance effective
interest rate or less 5years bearing sheet interest rate
2006 2006 2006 2006 2006 2006
$ 000 $ 000 $ 000 $ 000 $ 000 %
PARENT
Inte~~rest rate risk~~
Financial assets
Cash and deposits 5,976 - - - 5,976 5.47%
Trade and other receivables - - - 973 973 N/A
Total financial assets 5,976 - - 973 6,949
Financial liabilities
Commercial bills 4,976 - - - 4,976 6.43%
Trade and sundry creditors - - - 2,340 2,340 N/A
Total financial liabilities 4,976 - - 2,340 7,316

76

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITEDAGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTSNOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007For the year ended 30 June 2007

24. BUSINESS COMBINATIONS

(a) Summary of acquisition

  • On 5[th] June 2007 Agenix acquired 100% of the business and assets of Shanghai Rui Guang Bio-Pharma Development Co. (SHRG) and a 96% interest in Shanghai Yi Sheng Yuan Pharmaceutical Co. Ltd (YSY). The remaining 4% of YSY is owned by The Economic Association of Zhou Pu Town, Nunhui District, Shanghai and is disclosed in the financial statements as a minority interest. Agenix registered a wholly owned foreign enterprise, (WOFE) Agenix Bio-Pharmaceutical (Shanghai) Co., Ltd. to act as the Chinese resident holding Company for the acquisition of the acquired Chinese assets and companies. The Company has full control over the assets of SHRG.

The fair value of the identifiable assets and liabilities of SRHG and YSY combined as at the date of acquisition were:

Fair Value $'000
Acquiree's
carrying amount
$'000
Cash
306
306
Trade and other receivables
70
70
Other current assets
216
216
Fair Value $'000
Acquiree's
carrying amount
$'000
Cash
306
306
Trade and other receivables
70
70
Other current assets
216
216
Fixed assets
Construction in progress
537
537
4,631
4,631
5,760
5,760
Trade and other payables
Non-interest bearing loans and borrowings
Interest bearing loans and borrowings
(5,450)
(5,450)
(2,262)
(2,262)
(2,729)
(2,729)
(10,441)
(10,441)
~~Fair value of identifiable net assets~~
Intangible arising on acquisition (note 15)
~~(4,681)~~
15,182
~~10,501~~
Cost of the combination:
Cash paid
7,751
Cash payable (iii)
387
15,000,000 Share Options issued, at fair value (ii)
289
10,325,000 Milestone Options, at fair value (i)
510
Direct costs relating to the acquisition
1,564
10,501
The cash outflow on acquisition is as follows:
Cash acquired with the subsidiary
306
Cash consideration paid
(7,751)
Direct costs relating to the acquisition
(1,564)
(9,009)

Since acquisition date, 5[th] June 2007, Agenix Bio-Pharmaceutical (Shanghai) Co., Ltd has contributed $156,168 to the Group loss. No revenue from operations have been received during this period as the market launch of YouHeDing is still in progress. The disclosure of this sub-group’s financial results for the complete financial year would not be reflective of future performance expected from operations.

In accordance with AASB 3 Business Combinations, the acquirer has a period of 12 months for the date of acquisition to complete the final allocation of the purchase price to the fair value of the identifiable net assets. Initial accounting for the China acquisition has ~~provisionally allocated a fair value of $15.182 million to intellectual property. The Company will be performing a final assessmen~~ t of the allocation of fair value allocations to net assets and to intellectual property during the 2007 financial year. Should there be any subsequent adjustments, these adjustments will be recognised in future periods with corresponding adjustments to comparative ~~amounts.~~

77

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTSNO ES TO THE FINANCIAL STATEMENTS For the y ar ended 30 June 2007

24. BUSINESS COMBINATIONS (continued)

  • (i). Additional cash consideration of $393,348 is payable upon the granting of a drug license for the YouHeDing (YHD) drug.

  • (ii). Fifteen million options, over fully paid Agenix Limited shares, were issued on 17 April 2007 and were valued using the Black-Scholes model. The options are in five tranches of 3 million, subject to a 3 year vesting period, an expiry period of 6 years and exercise prices ranging from $0.30 for the first tranche and increasing in $0.10 increments for the final tranche of $A0.70. The options may be exercised at any time during the three year period after vesting (17 April 2010) and will expire automatically if not exercised during that period.

The Share Options, as noted above, have been valued using the Black-Scholes model, which takes into account factors including the option exercise price, the current level of volatility of the underlying share price, the risk free interest rate, expected dividends of the underlying share, current market price of the underlying share and expected life of the option.

  • (iii). These Milestone Options are grantable upon the commencement of Phase I trials in PRC for new anti-infective & anti-cancer drugs these events are currently considered probable. Under the terms of the Master Agreement, the exercise price per share option will be the weighted average share price for the 10 trading days prior to the achievement of the milestone but shall not be less than $0.16 The component of the investment cost outlined above as being represented by the Milestone Options utilises an exercise price of $0.16. The options may be exercised within five years after completion of achievement of each milestone.

The Milestones Options, as noted above, have been valued using the Black-Scholes model, which takes into account factors including the option exercise price, the current level of volatility of the underlying share price, the risk free interest rate, expected dividends of the underlying share, current market price of the underlying share and expected life of the option.

  • (b) In addition to the Milestone Options and Share Options, the acquisition agreement calls for the issuance of a number of options[(i)] on achievement of five specific milestones. As the achievement of these milestones is not currently considered probable, they have not been included in the cost of the combination. Following are details of the specific milestones:
Value of Milestone Milest one
RMB 2 0 million Receip
Republ
t by SHRG of a grant to the value of RMB 20 million from the government of the People’s
ic of China.
RMB 6 million Achiev ement of SHRG’s budgeted profit and cash flow during the first 12 months after completion.
RMB 5 million Achiev ement of sales of RMB 60 million ($9.9 million) over a period of 12 continuous months.
RMB 5 million Achiev ement of sales of RMB 100 million ($16.5 million) over a period of 12 continuous months.
RMB 5 million Achiev ement of netprofit of RMB 25 million over 12 continuous months.
  • (i). The number of options to be issued will be calculated by taking the value attributed to each milestone divided by the average Agenix share price for the ten days prior to achievement of the milestone (the Agenix share price may not be lower than $0.16 or higher than $0.50). The options expire five years from 21[st] May 2007, regardless of whether they are granted or not, and have an exercise price of $1.00.

(c) (c) Other information regarding the Business Combination.

As disclosed in note 26 (b)(i) and note 21, a loan for $5,419,000, bearing interest at 8%, was issued to the SHRG Vendors on 17 April 2007 to acquire ordinary shares in Agenix Limited. These shares are in escrow at 30 June 2007. The shares will not be released from escrow unless the shareholders warranties are satisfied. Both the loan and the related shares have not been recorded in the Balance Sheet however the details with regards to these transactions have been disclosed in full.

78

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

25. COMMITMENTS AND CONTINGENCIES

(a) Lease expenditure commitments

CONSOLIDATED CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
Operating leases (non-cancellable)
Minimum lease payments
not later than one year 917 458 71 86
later than one year and not later than five years 3,885 2,394 841 794
later than fiveyears 17,154 535 7 107
Aggregate lease expenditure contracted but not capitalised in the
accounts at reportingdate. 21,956 3,387 919 987

Operating leases have an average remaining lease term of 8 years. Assets that are the subject of operating leases are property and building.

Carole Park property

The Company has retained responsibility for the lease of the former Milton Pharmaceuticals office and warehouse in Carole Park, a suburb of Ipswich, Queensland. The property is currently sub-leased until April 2008.

Sale/leaseback of Acacia Ridge property

On 26 June 2006 Agenix signed a sale and leaseback agreement of the Company’s head office in Acacia Ridge. The initial lease term is 6 years, with two option periods of 4 years each. These lease commitments are included above.

Agenix Bio-pharmaceutical (Shanghai) Co.Ltd

YSY has entered into a lease agreement with a PRC owned Company, for a period of 15 years, expiring on 30 September 2020. SHRG has an office rental agreement ceasing on 22 May 2010

(b) Research and development commitments

  • At 30 June 2007, commitments in relation to the clinical trials currently being undertaken for ThromboView[®] , totalled $119,903 (2006: $1,050,587). These commitments will become due and payable not later than one year.

(c) Expenditure commitments relating to the disposal of the Milton Group and the Animal Health unit are disclosed in Note 6.

(d) Contingent liability

Legal dispute over consulting fees

A former consultant of the Company has commenced legal proceedings in Australia against the Company in relation to the Animal Health business transaction announced 7 April 2006. The consultant is seeking fees of $500,000 plus reimbursement of legal fees plus interest.

The Company has received legal advice. Based on that advise, the company believes that is has no liability whatsoever.

If the matter proceeds to trial, the Company’s potential exposure is estimated at $820,000. The company has recorded an accrual of $746,000 in the Balance Sheet as at 30 June 2007.

79

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

26. RELATED PARTY DISCLOSURE

Ultimate parent

Agenix Limited is the ultimate parent Company of the Consolidated Entity.

Wholly owned group transactions

Loans made by Agenix Limited to wholly owned subsidiaries, carry an interest rate of 10% (2006: 10%). The loans made by Agenix Limited to wholly owned subsidiaries and loans from wholly-owned subsidiaries to Agenix Limited are non-secured and have no formal repayment terms, but will not be repaid within 12 months from the date of these accounts.

INVESTMENT IN ORDINARY INVESTMENT IN ORDINARY
SHARES AT COST PERCENTAGE OWNED
2007 2006 2007 2006
$ $ % %
(a) Controlled entities of Agenix Limited
Agenix (Shanghai) Bio-pharma Co., Limited 71,735 - 100.00% -
AGEN Limited 11,810,000 11,810,000 100.00% 100.00%
Agen Biomedical - - 100.00% 100.00%
Agen Inc - - 100.00% 100.00%
Jemaka Pty Ltd - - 100.00% 100.00%
Agenix Asia Pacific Pte Ltd 2 2 100.00% 100.00%
Agen International Limited - - - 100.00%
Agen R&D Syndicate Pty Ltd - - - 100.00%
Biotech International Investments Ltd - 4,849,795 - 100.00%
Biopulp Research & Development Pty Ltd - - - 100.00%
Resource & Industry Limited - 10,186,192 - 100.00%
HCL Nominees PtyLtd - - - 100.00%
11,881,737 26,845,989

Agen Inc. was incorporated in the United States, Agenix Asia Pacific Pte Ltd was incorporated in Singapore and Agenix (Shanghai) Biopharma Co., Limited, was incorporated in the Peoples Republic of China. All other controlled entities were incorporated in Australia.

(b) Related party transactions

(b)
Related party transactions
CONSOLIDATED PARENT
2007 2006 2007 2006
$ 000 $ 000 $ 000 $ 000
(i) Loans to related parties
Begnning of the year - - - -
Loan advanced 5,419 - 5,419 -
End of year 5,419 - 5,419 -

Loan to SHRG vendors is for the acquisition of ordinary shares which is escrowed as detailed in note 21(b). Interest of 8% is charged on the outstanding balance. The loan is repayable in full upon sale of the shares. The Company is required to pay the net proceeds after netting off the amount of the shareholder loan plus accrued interest to the date of sale outstanding in relation to those shares to the shareholder.

This loan has not been recorded in the Balance Sheet as the shares related to the transaction have not been paid in full and are in escrow.

The following balances are outstanding from related parties at Reporting date.

(ii) Receivables from related parties
Receivable from ex-shareholders of China operations 46 - - -
Current receivable(interest on loan) 27 - 27 -
73 - 27 -

(iii) Payments to related parties

Directors remuneration payments to Karl Schlobohm are remitted to Prosperity Advisers. Karl Schlobohm is a Director of Prosperity Advisers.

80 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS

For the year ended 30 June 2007

26. RELATED PARTY DISCLOSURE (continued)

(c) Entities subject to class order

Pursuant to Class Order 98/1418 dated 5 May 1999, relief has been granted to all the above controlled entities of Agenix Limited, that were incorporated in Australia, from the Corporations Act 2001 requirement for preparation, audit and lodgement of their financial Reports.

Agenix Limited and the controlled entities subject to the Class Order have entered into a Deed of Cross Guarantee. The effect of the Deed is that Agenix Limited has guaranteed to pay any deficiency in the event of the winding up of the controlled entities and the controlled entities have guaranteed to pay any deficiency in the event of the winding up of Agenix Limited. Agen Inc. and Agenix Asia Pacific Pte Ltd and Agenix (Shanghai) Bio-pharmaceuticals Co. Ltd are not subject to the Deed of Cross Guarantee.

The consolidated Statements of Financial Performance and Position of the entities, which are members of the “Closed Group”, are as follows:

CLOSED GROUP
2007 2006
$ 000 $ 000
(i) Consolidated Income Statement
Loss before income tax (4,773) (3,721)
Income tax benefit/(expense) - -
Loss after income tax (4,773) (3,721)
Retained (losses) / profits at the beginning of the financial year (39,373)
(35,652)
Dividends provided for or paid - -
Aggregate amounts transferred to reserves - -
Retained losses at the end of the financial year (44,146) (39,373)
(ii) Consolidated Balance Sheet
Current assets
Cash assets 3,425 8,734
Receivables 14,093 788
Inventories - -
Prepayments 192 137
Other current assets 234 -
Current assets 17,944 9,659
Assets held for disposal 7,148 13,313
Total current assets 25,092 22,972
Non-current assets
Receivables 46 11
Shares in controlled entities 72 -
Property, plant and equipment 424 572
Intangible assets 48 101
Other non-current assets - -
Non-current assets 590 684
Assets held for disposal 772 -
Total non-current assets 1,362 684
Total assets 26,454 23,656
Current liabilities
Trade and other payables 2,027 1,617
Derivative financial instruments 654 -
Interest and non-interest bearing loans and borrowings - -
Interest-bearing liabilities - 4,976
Provisions 250 342
Current liabilities 2,931 6,935
Liabilities associated with assets held for sale 3,399 2,167
Total current liabilities 6,330 9,102
Non-current liabilities
Interest and non-interest bearing loans and borrowings - -
Provisions 136 341
Total non-current liabilities 136 341
Total liabilities 6,466 9,443
Net assets 19,988 14,213
Shareholders' equity
Contributed equity 59,392 50,114
Share option reserve 4,598 3,472
FX translation reserve (85) -
Loss attributable to outside equity (5) -
Retained losses (43,912)
(39,373)
Total shareholders' equity 19,988 14,213

81

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

27. EVENTS AFTER BALANCE SHEET DATE

Share Placement Announced 6[th] and 16[th] August 2007

On 6[th] and 16[th] August 2007 Agenix announced the successful placement to institutional and sophisticated investors in Australia and Asia of 44,687,500 shares at $0.16 per share to raise $7.15 million before costs.

28. AUDITOR’S REMUNERATION

The auditor of Agenix Limited is Ernst & Young.

CONSOLIDATED CONSOLIDATED PARENT PARENT
2007 2006 2007 2006
$ $ $ $
Amounts received or due and receivable by Ernst & Young for:
An audit or review of the financial report of the entity and any
other entity in the consolidated entity 95,000 108,000 45,000 108,000
Acquisition Audit China Operation 25,000 - 25,000 -
Disposals Audit Animal Health and Human Health 20,000 - - -
START Grant audit - 10,000 - 10,000
R&D tax concession work 20,000 37,000 20,000 37,000
AIFRS transition audit - 22,000 - 22,000
160,000 177,000 90,000 177,000

29. DIRECTOR AND EXECUTIVE DISCLOSURES

(a) Details of key management personnel

(i) Directors

  • R. Govindan Non-executive Chairman (from 7 December 2004; previously Executive Chairman) G. Ang Non-executive Director (resigned 31 August 2007) F.F. Wong Non-executive Director (resigned 20 November 2006) M. Davey Non-executive Director (resigned 12 December 2006) Dr A. Lamotte Non-executive Director N. Leggett Chief Executive Officer and Managing Director K. Schlobohm Non-executive Director (appointed 20 November 2006) J. Zhang Chief Executive Officer for China (commenced 17 April 2007 – appointed as a Director 27 August 2007) A. Lee Vui Han Non-executive Director (appointed 27 August 2007)

(ii) Executives

  • G. Mastroianni Vice President Sales and Marketing

  • M. Gerometta Director Research and Development

  • M. McArthur Operations Manager

C. Holmes Human Resources Manager R. Wang Chief Operating Officer for China (appointed 17 April 2007) S. Morrison Vice President Operations (made redundant 4 July 2006)

  • H. Roberts Director Clinical and Commercial Programs (ceased employment 13 July 2007) P. Toye Manager of Research (ceased employment 17 November 2006)

(b) Shares issued on exercise of compensation options (Consolidated)

No shares were issued on exercise of compensation options in the 2007 financial year.

82

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

29. DIRECTOR AND EXECUTIVE DISCLOSURES (continued)

(c) Option holdings of key management personnel (Consolidated)

Balance at
Balance at
Beginning
end of
of Period
Options
Options
Options
period
1 July 2006
Granted
Forfeited
Exercised
30 June 2007
Not
Total
Exercisable
Exercisable
VESTED AT 30 JUNE 2007
Directors
R. Govindan
300,000
-
-
-
300,000
300,000
-
300,000
-
-
-
-
-
-
Dr A. Lamotte
-
-
-
-
-
K. Schlobohm
-
-
-
-
-
GC. Ang
-
-
-
-
-
-
-
-
N. Leggett***
1,675,000
4,500,000
-
-
6,175,000
1,675,000
-
1,675,000
-
-
-
-
-
-
-
-
-
500,000
-
500,000
202,500
-
202,500
202,500
-
202,500
275,000
-
275,000
187,500
-
187,500
-
-
-
-
-
-
-
-
-
-
-
-
FF. Wong
-
-
-
-
-
M. Davey*
60,000
-
(60,000)
-
-
J. Zhang
-
-
-
-
-
D. Home

500,000
-
-
-
500,000
Executives
M. Gerometta
352,500
150,000
-
-
502,500
H. Roberts
352,500
150,000
-
-
502,500
G. Mastroianni
425,000
150,000
-
-
575,000
M. McArthur
255,000
150,000
-
-
405,000
C. Holmes
52,500
67,500
-
-
120,000
R. Wang
-
-
-
-
-
S. Morrison
450,000
-
(450,000)
-
-
P.Toye

255,000
-
(255,000)
-
-
4,677,500
5,167,500
(765,000)
-
9,080,000
3,342,500
-
3,342,500
  • At the time of Mr. Home's resignation on 15 December 2005, Mr Home retained the opportunity to exercise 500,000 options with an exercise price of $0.3228 per share. These options were not exercised and expired on 20 July 2007.

  • ** Mr. M. Davey, Mr. S. Morrison and Mr. P. Toye forfeited their options during the year, after ceased employment with Agenix.

  • *** Shareholder approval has been received to grant Mr. Leggett additional options as part of his remuneration package as Chief Executive Officer and Managing Director:

  • 500,000 options to be issued on each of 21 July 2007 and 21 July 2008 in conjunction with the annual Employee Option Plan.

For the 500,000 options issued on 21 July 2007, the exercise price was $0.24. The options will expire 6 years from grant date.

Balance at
Balance at
Beginning
end of
of Period
Options
Options
Options
period
1 July 2005
Granted
Forfeited
Exercised
30 June 2006
Not
Total
Exercisable
Exercisable
VESTED AT 30 JUNE 2006
Directors
R. Govindan
300,000
-
-
-
300,000
300,000
-
300,000
60,000
-
60,000
-
-
-
-
-
-
175,000
-
175,000
-
-
-
-
-
-
-
-
-
500,000
-
500,000
135,000
-
135,000
135,000
-
135,000
150,000
-
150,000
135,000
-
135,000
-
-
-
175,000
-
175,000
135,000
-
135,000
-
-
-
Dr A. Lamotte
-
-
-
-
-
K. Schlobohm
-
-
-
-
-
GC. Ang
-
-
-
-
-
N. Leggett
1,675,000
-
-
-
1,675,000
FF. Wong
-
-
-
-
-
M. Davey
60,000
-
-
-
60,000
J. Zhang
-
-
-
-
-
D. Home
4,000,000
-
(3,500,000)
-
500,000
Executives
M. Gerometta
202,500
150,000
-
-
352,500
H. Roberts
202,500
150,000
-
-
352,500
G. Mastroianni
275,000
150,000
-
-
425,000
M. McArthur
187,500
67,500
-
-
255,000
C. Holmes
-
52,500
-
-
52,500
S. Morrison
300,000
150,000
-
-
450,000
P. Toye
187,500
67,500
-
-
255,000
B. Calvin
500,000
250,000
(750,000)
-
-
7,890,000
1,037,500
(4,250,000)
-
4,677,500
1,900,000
-
1,900,000

83

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED NOTES TO THE FINANCIAL STATEMENTS For the year ended 30 June 2007

29. DIRECTOR AND EXECUTIVE DISCLOSURES (continued)

(d) Shareholding of key management personnel (Consolidated)

Shares on
Balance Shares granted Exercise of Net Change Balance
30 June 2007 1 July 2006 as Compensation Options Other 30 June 2007
Directors
R. Govindan 5,062,500 - - 1,724,446 6,786,946
Dr A. Lamotte - - - - -
K. Schlobohm - - - 123,750 123,750
GC. Ang - - - - -
N. Leggett 629,000 - - 1,371,000 2,000,000
FF. Wong 3,125,000 - - (2,500,000) 625,000
M. Davey 175,323 - - (175,323) -
J. Zhang - - - - -
Executives
M. Gerometta - - - - -
H. Roberts - - - - -
G. Mastroianni - - - - -
M. McArthur - - - - -
C. Holmes - - - - -
R. Wang - - - - -
P. Toye - - - - -
8,991,823 - - 543,873 9,535,696
Shares on
Balance Shares granted Exercise of Net Change Balance
30 June 2006 1 July 2005 as Compensation Options Other 30 June 2006
Directors
R. Govindan 4,050,000 - - 1,012,500 5,062,500
Dr A. Lamotte - - - - -
K. Schlobohm - - - - -
GC. Ang - - - - -
N. Leggett 185,000 - - 444,000 629,000
FF. Wong 2,500,000 - - 625,000 3,125,000
M. Davey 140,323 - - 35,000 175,323
J. Zhang - - - - -
Executives - - - - -
M. Gerometta - - - - -
H. Roberts - - - - -
G. Mastroianni - - - - -
M. McArthur - - - - -
C. Holmes - - - - -
P.Toye - - - - -
6,875,323 - - 2,116,500 8,991,823

84

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED DIRECTORS’ DECLARATION

In accordance with a resolution of the Directors of Agenix Limited, I state that:

  1. In the opinion of the Directors:

  2. (a) the financial statements, notes and the additional disclosures included in the Remuneration Report in Directors’ Report of the Company and of the Consolidated Entity are in accordance with the Corporations Act 2001, including:

  3. (i) giving a true and fair view of the Company’s and the Consolidated Entity’s financial position as at 30 June 2007 and of their performance for the year ended on that date; and

  4. (ii) complying with Accounting Standards and Corporations Regulations 2001; and

  5. (b) there are reasonable grounds to believe that the Company will be able to pay its debts as and when they become due and payable.

  6. This declaration has been made after receiving the declarations required to be made to the Directors in accordance with section 295A of the Corporations Act 2001 for the financial period ending 30 June 2007.

  7. In the opinion of the Directors, as at the date of this declaration, there are reasonable grounds to believe that the members of the Closed Group identified in Note 26 will be able to meet any obligations or liabilities to which they are or may become subject, by virtue of the Deed of Cross Guarantee.

On behalf of the Board

==> picture [118 x 68] intentionally omitted <==

____Neil Leggett _CEO and Managing Director 30 SEPTEMBER 2007

85

AGENIX LIMITED ANNUAL REPORT 2007

==> picture [533 x 797] intentionally omitted <==

86 AGENIX LIMITED ANNUAL REPORT 2007

==> picture [548 x 793] intentionally omitted <==

AGENIX LIMITED ANNUAL REPORT 2007 87

AGENIX LIMITED ADDITIONAL INFORMATION

Additional information required by the Australian Stock Exchange Ltd and not shown elsewhere in this Report is as follows. The information is current as at close of business on 26[th] September 2007.

(a) Distribution of ordinary shareholders and option holders:

ORDINARY SHARES
Category (size of holding) Number of holders Number of shares
1 - 1,000 155 98,792
1,001 - 5,000 1,173 3,732,155
5,001 - 10,000 838 6,947,865
10,001 - 100,000 1,518 49,436,480
100,001 and over 284 323,946,753
Total 3,968 384,162,045
Shareholders holdingless than a marketableparcel of shares 523 756,083
Number of Number of Weighted average
Option Issue Option Category holders options Grant date Vesting date Expiry date exercise price $
O 15 Options 1 250,000 27 December 2002 22 September 2004 22 September 2009 0.3928
O 19 Options 1 200,000 1 January 2006 1 January 2008 1 January 2012 0.4000
O23 Options 1 3,000,000 6 June 2007 18 April 2010 17 April 2013 0.3000
O24 Options 1 3,000,000 6 June 2007 18 April 2010 17 April 2013 0.4000
O25 Options 1 3,000,000 6 June 2007 18 April 2010 17 April 2013 0.5000
O26 Options 1 3,000,000 6 June 2007 18 April 2010 17 April 2013 0.6000
O27 Options 1 3,000,000 6 June 2007 18 April 2010 17 April 2013 0.7000
OP 8 Employee options 22 326,250 14 March 2003 25 July 2004 25 July 2008 0.3328
O 10 Employee options 26 688,750 6 October 2003 21 July 2005 21 July 2009 0.4128
O 16 Employee options 32 784,500 21 September 2004 21 July 2006 21 July 2010 0.6728
O 17 Employee options 1 1,250,000 18 November 2004 18 November 2006 18 November 2010 0.5428
O 18 Employee options 34 1,065,750 31 August 2005 21 July 2007 21 July 2011 0.2928
O 20 Employee options 36 1,140,000 13 September 2006 21 July 2008 21 July 2012 0.2200
O21 Employee options 1 4,000,000 17 November 2006 15 December 2007 15 December 2011 0.5300
O22 Employee options 1 500,000 17 November 2006 21 July 2008 21 July 2012 0.2500
O28 Employee options 9 2,880,000 31 August 2007 21 July 2007 21 July 2009 0.2400
O29 Employee options 26 2,600,000 31 August 2007 21 July2009 21 July2013 0.2400
30,685,250

88 AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED ADDITIONAL INFORMATION

(b) 20 Largest shareholders - fully paid ordinary shares

(b) 20 Largest shareholders - fully paid ordinary shares
Number of % of issued
Shareholder ordinary shares ordinary shares
1. Pacific Superannuation Pty Limited 34,038,934 8.86
2. W & Z Holdings Company Limited 33,868,520 8.82
3. HSBC Custody Nominees (Australia) Limited 20,680,616 5.38
4. ANZ Nominees Limited 19,426,812 5.06
5. Citicorp Nominess Pty Limited 18,455,091 4.80
6 Annmac Investments Pty Ltd 18,000,000 4.69
7. New Brooklyn Holdings Limited 15,000,000 3.90
8. Merrill Lynch (Aust) Nominees Pty Limited 11,390,500 2.97
9. Success Communication Ltd 6,891,011 1.79
10. Asiaeagle International Limited 6,171,875 1.61
11. DBS Vickers Securities (Singapore) Pte Ltd 4,677,107 1.22
12. Mr Anthony Lee Vui Han 4,375,000 1.14
13. Mr Sing En Chan 4,350,000 1.13
14. HSBC Custody Nominees (Australia) Limited 4,317,000 1.12
15. DMG & Partners Securities Pte Ltd Clients A/C 4,150,000 1.08
16. UOB Kay Hian Private Limited Clients A/C 4,006,438 1.04
17. F H Nominees Pty Ltd 3,500,000 0.91
18. CIMB-GK Securities Pte Ltd Client A/C 2,386,500 0.62
19. Mr Davy Devaraj 2,087,500 0.54
20. Clear Island Investments PtyLtd Super Fund A/C 2,000,000 0.52
219,772,904 57.20

(c) Substantial shareholders

(c) Substantial shareholders
Number of % of issued
ordinary shares ordinary shares
Pacific Superannuation Pty Limited 34,038,934 8.86
W & Z Holdings CompanyLimited 33,868,520 8.82

(d) Voting rights

No restrictions. On show of hands, every member or proxy present shall be entitled to one vote unless a poll is called in which case every share shall have one vote.

(e) Stock exchange listing

Quotation has been granted for all the ordinary shares of Agenix Limited on all Member Exchanges of the Australian Stock Exchange Limited.

(f) Directors interest in equity

The interests of each Director in the share capital of Agenix Limited as disclosed by the Register of Director’s shareholding.

Options Options Options Options Options Options Options Options
Ordinary Listed Expiring Expiring Expiring Expiring Expiring Expiring Expiring Expiring
Name shares Options 21/07/2009 21/07/2010 18/11/2010 15/12/2011 21/07/2012 21/07/2009 17/4/2013 21/07/2013
R. Govindan 6,786,946 439,130 -
-
-
-
-
- -
F.F. Wong 1,250,000 -
-
-
-
-
-
- -
M. Davey - - - -
- -
-
- -
Dr A. Lamotte - - - -
- -
-
- -
A Lee Vui Han 4,375,000 291,666 - -
N. Leggett 2,000,000 238,333 175,000 250,000 1,250,000 4,000,000 500,000 - 500,000
K. Schlobohm 123,750 5,250 -
-
-
-
-
- -
J. Zhang 33,868,520 - - -
- -
-
900,000 15,000,000 400,000

89

AGENIX LIMITED ANNUAL REPORT 2007

AGENIX LIMITED Corporate Information

ABN 58 009 213 754

This annual Report covers both Agenix Limited as an individual entity and the Consolidated Entity comprising Agenix Limited and its subsidiaries. The Group’s functional and presentation currency is AUD ($).

A description of the Group’s operations and of its principal activities is included in the review of operations and activities in the Directors’ Report on page 18. The Directors’ Report is not part of the Financial Report.

Directors

Ravindran Govindan (Non-Executive Chairman) Neil Leggett (Chief Executive Officer and Managing Director) Karl Schlobohm (Non-Executive Director) Jonathan Zhang (CEO China Operations) Dr Andre Lamotte (Non-Executive Director) Anthony Lee Vui Han (Lee) (Non-Executive Director)

Company Secretary

Karl Schlobohm

Registered Office and Principal Place of Business

7 Durbell Street Acacia Ridge Qld 4110 Tel: +61 (07) 3370 6396 Fax: +61 (07) 3370 6370 Email: [email protected] Website: www.agenix.com

Share Register

Computershare Investor Services Pty Ltd Level 27, 345 Queen Street Brisbane Qld 4000 Tel: 1300 552 270 Fax: +61 (07) 3229 9860

Solicitors

DLA Phillips Fox

Bankers

Westpac Banking Corporation

Auditors

Ernst & Young

Tax Advisers

Johnston Rorke

90 AGENIX LIMITED ANNUAL REPORT 2007