CCSB — Annual Report 2021

Nov 12, 2021

Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries

Consolidated financial statements and Auditor's Report 2021 and 2020

(Stock Code: 1762)

Address: No.1, Dongxing St., Shulin Dist., New Taipei City Tel: (02)8684-3318

----------------------------------------------------------------------------------------------------------------------------------------------------------For the convenience of readers and for information purpose only, the auditors’ report and the accompanying financial statements have been translated into English from the original Chinese version prepared and used in the Republic of China. In the event of any discrepancy between the English version and the original Chinese version or any differences in the interpretation of the two versions, the Chinese-language auditors’ report and financial statements shall prevail.

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries The 2021 and 2020 Consolidated Financial Report and Independent Auditor’s Report Table of Contents

		Item	Page
1.	Cover		1
2.	Table	of Contents	2 ~ 3
3.	Declaration		4
4.	Auditor's Report		5 ~ 9
5.	Consolidated Balance Sheet		10 ~ 11
6.	Consolidated comprehensive income statements		12 ~ 13
7.	Consolidated statement of changes in equity		14
8.	Consolidated cash flow statement		15 ~ 16
9.	Notes	to consolidated financial statement	17 ~ 56
	(1)	Company history	17
	(2)	Date On Which And Procedures By Which The Financial Reports Were
		Authorized For Issuance.	17
	(3)	Application of New Standards, Amendments and Interpretations	17 ~ 18
	(4)	Summary of significant accounting policies	18 ~ 26
	(5)	Critical accounting judgments, estimates and key sources of assumption
		uncertainty	27
	(6)	Descriptions of major accounts	27 ~ 43
	(7)	Related party transactions	43 ~ 44
	(8)	Collateralized assets	44

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	Item	Page
(9)	Significant contingent liabilities and unrecognized contractual	44 ~ 45
	commitments
(10)	Losses due to major disasters	45
(11)	Major post-balance sheet events	45
(12)	Other	45 ~ 53
(13)	Notes of disclosure	53
(14)	Segment information	54 ~ 55

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. The Affiliate’s Declaration of Consolidated Financial Statements

In 2021 (from January 1, 2021 to December 31, 2021), the companies that should be included in the consolidated financial reports of affiliated companies based on the "Criteria Governing Preparation of Affiliation Reports, Consolidated Business Reports and Consolidated Financial Statements of Affiliated Enterprises" and the companies that should be included in the consolidated financial reports of subsidiaries based on the "Consolidated and separate financial statements" of Section 10 of International Financial Reporting Standards were the same. The related information that should be disclosed in the consolidated financial statements of affiliated companies are also already disclosed in the consolidated financial reports for subsidiaries, so that the consolidated financial statements of affiliated companies would not be published separately.

Declared by:

Company name: Chunghwa Chemical Synthesis & Biotech Co., Ltd.

March 29, 2022

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Auditor's Report (2022) Cai-Shen-Bao-Zi No. 21004240

To Chunghwa Chemical Synthesis & Biotech Co., Ltd.,

Audit opinion

We have audited the accompanying proprietary consolidated balance sheet of Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries (hereinafter referred to as Chunghwa Group) as of December 31, 2021 and 2020 and the related consolidated statements of income, of changes in shareholders’ equity and of cash flows and Notes to consolidated financial statement (including significant accounting policies) for the years then ended.

In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial position of Chunghwa Group as of December 31, 2021 and 2020, and the results of its operations and its cash flows for the years then ended in conformity with the “Regulations Governing the Preparation of Financial Reports by Securities Issuers,” and International Financial Reporting Standards (IFRS) that was recognized by the Financial Supervisory Commission, International Accounting Standards, Interpretations, and Notices (IFRS), International Accounting Standards (IAS), Interpretation (IFRIC) and Interpretative Announcement (SIC).

Basis of an audit opinion

We conducted our audit in accordance with the “Rules Governing the Examination of Financial Statements by Certified Public Accountants” and generally accepted auditing standards. The responsibilities of the independent auditor under these standards will be further explained in the paragraph of “independent auditor’s responsibility for consolidated financial statements.” The personnel of the CPA Firm subject to the independence requirement have acted independently from the business operations of Chunghwa Group in accordance with the Code of Ethics and with other responsibilities of the Code of Ethics performed. We believe that our audit provides a reasonable basis for our opinion.

Key Audit Matters

The “key audit matters” means that the independent auditor has used their professional judgment to audit the most important matters on the 2021 consolidated financial statements of Chunghwa Group. The key audit matters have been responded to in the process of auditing the consolidated financial statements as a whole and forming an audit opinion; therefore, the independent auditor does not express an opinion on these matters separately.

The key audit items from the 2021 consolidated financial statement of Chunghwa Chemical Synthesis and Biotech Co., Ltd. are presented below:

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Accounting assessment of inventory valuation

Description of the matter

See Note 4 (12) in the consolidated financial report regarding the accounting policy on inventory valuation, Note 5 (2) for the accounting assessment and hypothetical uncertainty on inventory valuation, and Note 6 (4) for the description of the inventory account.

Chunghwa Chemical Synthesis & Biotech Ltd. is engaged mainly in the production and sale of active pharmaceutical ingredients. Since drug tests are now stricter and it takes a longer time to obtain drug certificates, the risk of inventory loss or obsolescence becomes higher. Since the inventories involve large amounts of money and large numbers of items that require laborious work by human beings to identify expired or damaged goods, we regard the assessment of allowance to reduce inventory to market as a key audit item.

The responsive auditing process

Our key audit procedures performed in respect of the above area included the following:

1. Assessing the policy on allowance to reduce inventory to market in accordance with our understanding of the Company's operations and the nature of the business.

2. Performing sampling tests to examine if the market price of net realized value is consistent with the Company's policy, and randomly examining the accuracy of the selling price of individual inventory parts and the way net realized value is calculated.

3. Obtain out-of-date inventory details that are identified by the management, check the related information and verify the account records.

Checking whether the time point of sales income recognition is appropriate

Description of the matter

For the accounting policy on the recognition of income, please refer to Note 4 (26) of the consolidated financial statement. For information on income accounts, please refer to Note 6 (15) of the consolidated financial statement. As stated in the accounting policies, the sales revenue is recognized when products are delivered to customers who have discretionary power in channels and prices of products sold and Chunghwa Chemical Synthesis and Biotech has no outstanding performance obligations which may affect customers’ acceptance of products. As exports are the main source of income for Chunghwa Chemical Synthesis & Biotech Co., Ltd., the terms of business agreed upon between the Company and its customers are the basis of income assessment. However, such a process often involves a lot of manpower for verification and may lead to inappropriate income recognition time points. Therefore, we regard the sales income recognition time points as a key audit item.

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The responsive auditing process

Our key audit procedures performed in respect of the above area included the following:

1. The group's operating procedure for and internal control on income recognition time points were examined and assessed, while the Company's internal control on sales deadlines was tested to verify the correctness of the income recognition time points.

2. The execution of sales and income over a certain period before and after the time periods covered in the financial report were examined with the packing lists, customer orders and declaration forms in order to confirm that income was recognized at appropriate periods.

Other matters - individual financial report

Chunghwa Group has compiled its 2021 and 2020 individual financial statements, for which we issued unqualified opinion.

The responsibility of the management and management units to the consolidated financial statements

The responsibility of the management is to have the consolidated financial statements presented fairly, in all material respects, in accordance with the “Regulations Governing the Preparation of Financial Reports by Securities Issuers”, and International Financial Reporting Standards (IFRS) that was recognized by the Financial Supervisory Commission, International Accounting Standards, Interpretations, and Notices (IFRS), International Accounting Standards (IAS), Interpretation (IFRIC) and Interpretative Announcement (SIC); also, maintain the necessary internal controls related to the consolidated financial statements in order to ensure that the consolidated financial statements are free of any material misstatement arising from fraud or errors.

While preparing the consolidated financial statements, the management’s responsibility also includes assessing the continuing operation of Chunghwa Group, the disclosure of the relevant matters, and the adoption of the accounting base for continuing operation, unless the management intends to liquidate Chunghwa Group or cease the business operation, or there is lack of any alternative except for liquidation or suspension.

The governance units (including the Audit Committee) of Chunghwa Group are responsible for supervising the financial reporting process.

The responsibilities of the independent auditor to the consolidated financial statements

The purpose of the independent auditor’s auditing the consolidated financial statements is to obtain reasonable assurance about whether the consolidated financial statements are free of material misstatement arising from fraud or errors and with an audit report issued. Reasonable assurance means a high degree of assurance. However, the audit conducted in accordance with generally accepted auditing standards of the R.O.C. does not guarantee having any material misstatement in the individual financial statements detected. Material misstatement could arise from fraud or errors. If the misstated amount or aggregated amount is reasonably expected to affect the economic decisions made by the users of the consolidated financial statements, it is considered significant.

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The independent auditor when conducting the audit in accordance with generally accepted auditing standards of the R.O.C. exercises professional judgment and maintains professional skepticism. The independent auditor also performs the following tasks:

1. Identify and evaluate the risk of material misstatement arising from fraud or errors of the consolidated financial statements; design and implement proper responsive measures to the risk assessed; also, obtain sufficient and adequate audit evidences for forming an audit opinion. The risk of fraud may involve conspiracy, forgery, deliberate omission, false declaration, or violating internal control; therefore, the risk of material misstatement arising from the undetected fraud is higher than that caused by errors.

2. Obtain necessary understanding on the internal control related to the audit in order to design appropriate audit procedures under the circumstance, but the purpose is not to express an opinion on the effectiveness of the internal control of Chunghwa Group.

3. Assess the appropriateness of the accounting policies adopted by the management; also, the reasonableness of the accounting estimates and related disclosures made.

4. Base on the audit evidence obtained to make conclusions on the suitability of the accounting base for continuing operation base adopted by the management and whether or not the events or circumstances causing significant doubts to the continuing operation ability of Chunghwa Group are with significant uncertainties. If the independent auditor believes that such events or circumstances are with significant uncertainties, it is necessary to remind the users of the consolidated financial statements in the audit report to pay attention to the relevant disclosure or to revise the audit opinion when such disclosures are inappropriate. The conclusion of the independent auditor is based on the audit evidence obtained as of the audit report date. However, future events or circumstances may result in the inability of Chunghwa Group to continue operating.

5. Assess the overall expression, structure, and content of the consolidated financial statements (including the relevant notes) and whether or not the relevant transactions and events in the consolidated financial statements are presented fairly.

6. Obtain sufficient and appropriate audit evidence on the financial information of business entities within the Group in order to express an opinion on the consolidated financial statements. The independent auditor is responsible for guiding, supervising, and implementing the audit of the Group; also, is responsible for forming an opinion on the audit of the Group.

The matters communicated by the independent auditor to the governing unit include the scope and timing of the planned audit, and the significant findings (including the major nonconformities of internal controls identified in the auditing process).

The independent auditor has provided the declaration of independence of the CPA Firm personnel subject to the Code of Ethics to the governing unit; also, it has communicated with the governing unit regarding the relationship and other matters (including the relevant protection measures) that may affect the independence of the independent auditor.

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The independent auditor has based on the communications with the governing unit to determine the key audit matters to be performed on the 2021 consolidated financial statements of Chunghwa Group. The independent auditor shall state the key audit matters in the audit report except for the specific matters prohibited by law from being disclosed, or, in rare cases; the independent auditor decides not to have specific matters communicated in the audit report since the negative effect of such disclosure can be reasonably expected to be greater than the increase of public interest.

PwC Taiwan

March 29, 2022

Notice to Readers

The accompanying consolidated financial statements are intended only to present the consolidated financial position, financial performance and cash flows in accordance with accounting principles and practices generally accepted in the ROC and not those of any other jurisdictions. The standards, procedures and practices to audit such consolidated financial statements are those generally applied in the ROC.

For the convenience of readers, the independent auditors’ report and the accompanying consolidated financial statements have been translated into English from the original Chinese version prepared and used in the ROC. If there is any conflict between the English version and the original Chinese version or any difference in the interpretation of the two versions, the Chinese-language independent auditors’ report and consolidated financial statements shall prevail.

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries Consolidated Balance Sheet December 31, 2021 and 2020

Unit: NTD thousand

Assets	Additional notes 6 (1) 6 (15) 6(3) 6(3) 7 4(3) 6 (4) 6 (2) 6 (5) 6 (6) 6 (7) 6 (21) 6 (11) and 8	December 31, 2021 Amount % $ 195,250 5 - - 480 - 355,923 8 23,477 1 16,127 - - - 753,850 17 11,971 - 1,357,078 31 26,726 1 1,032,860 24 1,866,152 43 2,313 - 10,700 - 1,803 - 24,480 - 58,649 1 3,023,683 69 $ 4,380,761 100	December 31, 2020 Amount % $ 148,625 5 21 - 344 - 315,610 10 41,952 2 9,653 - 21 - 481,244 15 4,132 - 1,001,602 32 32,456 1 511,434 16 1,539,251 49 3,110 - 10,700 - 1,293 - 16,758 1 30,536 1 2,145,538 68 $ 3,147,140 100
		Amount $ 195,250 - 480 355,923 23,477 16,127 - 753,850 11,971 1,357,078 26,726 1,032,860 1,866,152 2,313 10,700 1,803 24,480 58,649 3,023,683 $ 4,380,761	Amount $ 148,625 21 344 315,610 41,952 9,653 21 481,244 4,132 1,001,602 32,456 511,434 1,539,251 3,110 10,700 1,293 16,758 30,536 2,145,538 $ 3,147,140
Current assets 1100 Cash and cash equivalents 1140 Contract assets - Current 1150 Notes receivable-net 1170 Net accounts receivable 1180 Account receivables-Related Parties- net 1200 Other receivable 1220 Current income tax assets 130X Inventory 1410 Prepayments 11XX Total of Current Assets Non-Current assets 1510 Financial assets that are measured at fair value through profit or loss-non-current 1550 Investments accounted for by the equity method 1600 property , plant, and equipment 1755 Right-of-use assets 1760 Real property for investment- net 1780 Intangible assets 1840 Deferred income tax assets 1900 Other current non-assets 15XX Total of Non-Current Assets 1XXX Total assets

(Continued next page)

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries Consolidated Balance Sheet December 31, 2021 and 2020

Liabilities and equity	Additional notes 6 (8) 6 (15) 6 (9) and 7 6 (10) 6 (21) 6 (12) 6 (13) 6 (14) 9 11	December 31,2021 Amount % $ 150,000 3 73,988 2 1,215 - 77,550 2 297,541 7 31,047 1 1,320 - 2,509 - 635,170 15 600,000 13 250,299 6 1,018 - 851,317 19 1,486,487 34 775,600 18 334,323 8 226,015 5 183,296 4 1,335,088 30 39,762 1 2,894,084 66 190 - 2,894,274 66 $ 4,380,761 100	Unit: NTD thousand December 31,2020 Amount % $ - - 3,657 - 1,215 - 96,495 3 187,686 6 106,544 4 2,252 - 2,310 - 400,159 13 - - 247,499 8 819 - 248,318 8 648,477 21 775,600 25 334,323 10 171,229 5 183,296 6 1,030,235 33 3,719 - 2,498,402 79 261 - 2,498,663 79 $ 3,147,140 100
		Amount $ 150,000 73,988 1,215 77,550 297,541 31,047 1,320 2,509 635,170 600,000 250,299 1,018 851,317 1,486,487 775,600 334,323 226,015 183,296 1,335,088 39,762 2,894,084 190 2,894,274 $ 4,380,761	Amount $ - 3,657 1,215 96,495 187,686 106,544 2,252 2,310 400,159 - 247,499 819 248,318 648,477 775,600 334,323 171,229 183,296 1,030,235 3,719 2,498,402 261 2,498,663 $ 3,147,140
Current liabilities 2100 Shot-term borrowings 2130 Contract liabilities - Current 2150 Payable notes 2170 Accounts payable 2200 Other payable 2230 Current Income Tax Liability 2280 Lease liabilities – Current 2399 Other current liabilities- other 21XX Total of current liabilities Non-current liabilities 2540 Long-term borrowings 2570 Deferred income tax liabilities 2580 Lease liabilities – Non-current 25XX Total of non-current liabilities 2XXX Total liabilities Attributable to owners of the parent company Share capital 3110 Ordinary shares capital Capital reserve 3200 Capital reserve Retained earnings 3310 Legal earnings reserve 3320 Special earnings reserve 3350 Undistributed earnings Other equity 3400 Other equity 31XX Equity attributable to owners of the parent Company 36XX non-controlling interests 3XXX Total equity Significant contingent liabilities and unrecognized contractual commitments Major post-balance sheet events 3X2X Total liabilities and equity

Please refer to the notes enclosed in the consolidated financial reports that are an integral part of the consolidated financial statements.

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries Consolidated comprehensive income statements January 1 to December 31, 2021 and 2020

Unit: NTD thousand (except EPS in NTD)

Item

2021 2020 Additional notes Amount % Amount % 6 (15) and 7 $ 1,934,702 100 $ 1,543,589 100 6(4)(20) and 7 ( 985,314)( 51) ( 856,836)( 56) 949,388 49 686,753 44 6 (20) and 7 ( 144,667) ( 8) ( 109,696) ( 7) ( 95,227) ( 5) ( 92,408) ( 6) ( 252,674) ( 13) ( 215,729) ( 14) ( 18,345) ( 1) - - ( 510,913) ( 27) ( 417,833)( 27) 438,475 22 268,920 17 6 (16) 181 - 424 - 6 (17) 18,500 1 10,834 1 6 (18) ( 6,322) - 336,980 22 6 (19) ( 3,321) - ( 4,757) - 6 (5) 50,100 2 37,896 2 59,138 3 381,377 25 497,613 25 650,297 42 6 (21) ( 96,563)( 5)( 118,234)( 8) $ 401,050 20 $ 532,063 34

4000 Operating revenues 5000 Operating cost 5900 Operating gross profit Operating expenses 6100 Marketing expenses 6200 Administrative expenses 6300 Research and development expenses 6450 Expected loss on credit impairment 6000 Total operating expenses 6900 Operating profit Non-operating revenues and expenses 7100 Interest income 7010 Other revenue 7020 Other profits and losses 7050 Financial costs 7060 Shareholding in the affiliated companies and joint ventures under the equity method 7000 Total non-operating revenues and expenses 7900 Earnings before tax 7950 Income tax expense 8200 Current period net profit

(Continued next page)

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries Consolidated comprehensive income statements January 1 to December 31, 2021 and 2020

Unit: NTD thousand (except EPS in NTD)

Item	2021 Additional notes Amount 6 (11) $ 1,750 111,209 6 (21) ( 350) 112,609 ( 507) ( 868) ( 1,375) $ 111,234 $ 512,284 $ 400,778 $ 272 $ 512,022 $ 262 6 (22) $ $	2021	2020 % Amount - ( $ 244) 6 13,848 - 49 6 13,653 - ( 1,028) - 1,031 - 3 6 $ 13,656 26 $ 545,719 20 $ 531,873 - $ 190 26 $ 545,550 - $ 169 5.17 $ 5.12 $	2020	% - 1 - 1 - - - 1 35 34 - 35 - 6.86 6.79
Other comprehensive income (net) Items not re-classified under profit or loss 8311 Defined benefit plan revaluation amount and volume 8320 The proportion of other comprehensive incomes from associates, and equity joint-ventures accounted for under the equity method – not reclassified as profit and loss 8349 Income tax related to accounts not being reclassified 8310 Total amount of items not reclassified to profit or income Items that may be re-classified subsequently under profit or loss 8361 Exchange differences arising from translating the financial statements of foreign operations 8370 The proportion of other comprehensive incomes from associates, and equity joint-ventures accounted for under the equity method – may be reclassified as profit and loss. 8360 Total amount of items probably reclassified to profit or loss subsequently 8300 Other comprehensive income (net) 8500 Total comprehensive income for the period Profit attributable to: 8610 Owners of parent 8620 non-controlling interests Total comprehensive income attributable to: 8710 Owners of parent 8720 non-controlling interests Earnings per share 9750 Base earnings per share 9850 Diluted earnings per share
		$		$

Please refer to the notes enclosed in the consolidated financial reports that are an integral part of the consolidated financial statements.

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries Consolidated statement of changes in equity January 1 to December 31, 2021 and 2020

Unit: NTD thousand

2020 Balance as of January 1, 2020 Current period net profit Current other comprehensive income Total comprehensive income for the period The 2019 appropriation and distribution of earnings: Legal earnings reserve Cash dividend The reinvested company(ies) disposed of equity instruments measured at the fair value through other comprehensive profits and losses Change in non-controlling interests Balance at December 31, 2020 January 1 to December 31, 2021 Balance at January 1, 2021 Current period net profit Current other comprehensive income Total comprehensive income for the period The 2020 appropriation and distribution of earnings: Legal earnings reserve Cash dividend The reinvested company(ies) disposed of equity instruments measured at the fair value through other comprehensive profits and losses Change in non-controlling interests Balance at December 31, 2021	Additional notes								Attribut	able to owners ofthe	able to owners ofthe	able to owners ofthe	parent company								non-controlling interests		Total equity
			Ordinary shares capital		Capital	re	serve			Retained earnings					Other	equity			Total
					Issuance premium		Others		Legal earnings reserve	Special earnings reserve			Undistributed earnings		Exchange differences arising from translating the financial statements of foreign operations		Unrealized gain or loss on financial assets at fair value through other comprehensive profit or loss
	6 (14) 6 (14)		$ 775,600 - - - - - - - $ 775,600 $ 775,600 - - - - - - - $ 775,600		$ 333,746 - - - - - - - $ 333,746 $ 333,746 - - - - - - - $ 333,746		$ 577 - - - - - - - $ 577 $ 577 - - - - - - - $ 577		$159,344 - - - 11,885 - - - $171,229 $171,229 - - - 54,786 - - - $226,015		$ 183,296 - - - - - - - $ 183,296 $ 183,296 - - - - - - - $ 183,296		$ 556,306 531,873 ( 385 ) 531,488 ( 11,885 ) ( 62,048 ) 16,374 - $1,030,235 $1,030,235 400,778 4,412 405,190 ( 54,786 ) ( 116,340 ) 70,789 - $1,335,088		($ 2,691 ) - 24 24 - - - - ($ 2,667 ) ($ 2,667 ) - ( 1,365 ) ( 1,365 ) - - - - ($ 4,032 )		$ 8,722 - 14,038 14,038 - - ( 16,374 ) - $ 6,386 $ 6,386 - 108,197 108,197 - - ( 70,789 ) - $ 43,794		$ 2,014,900 531,873 13,677 545,550 - ( 62,048 ) - - $ 2,498,402 $ 2,498,402 400,778 111,244 512,022 - ( 116,340 ) - - $ 2,894,084		$ 232 190 ( 21 ) 169 - - - ( 140 ) $ 261 $ 261 272 ( 10 ) 262 - - - ( 333 ) $ 190	$ 2,015,132 532,063 13,656 545,719 - ( 62,048 ) - ( 140 ) $ 2,498,663 $ 2,498,663 401,050 111,234 512,284 - ( 116,340 ) - ( 333 ) $ 2,894,274

Please refer to the notes enclosed in the consolidated financial reports that are an integral part of the consolidated financial statements.

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries Consolidated cash flow statement

January 1 to December 31, 2021 and 2020

Unit: NTD thousand

Cash flow from operating activities Pre-tax profit for the current period Adjustments Income, expense, and loss Depreciation Amortization Expected loss on credit impairment Interest expenses Net profit from financial assets and liabilities at fair value through profit and loss Interest income Shareholding in the affiliated companies and joint ventures under the equity method Gain in disposal of property, plant and equipment Changes in assets/liabilities relating to operating activities Net changes in assets relating to operating activities De-capitalization refunded monies of financial assets at fair value through profit or loss Contract assets - Current Notes receivable-net Net accounts receivable Accounts receivable-related parties (net) Other receivable Inventory Prepayments Net defined benefit assets Net changes in liabilities relating to operating activities Contract liabilities - Current Payable notes Accounts payable Other payable Other current liabilities-others Net cash provided by operating activities Interest received Dividends received Interest paid Income tax paid Net cash inflow from operating activities

Additional notes January 1 to December 31, 2021 January 1 to December 31, 2020 $ 497,613 $ 650,297 6 (20) 130,414 129,545 6 (20) 1,579 1,609 18,345 - 6 (19) 3,321 4,757 6 (2) (18) ( 3,270 ) ( 4,296 ) 6 (16) ( 181 ) ( 424 ) 6 (5) ( 50,100 ) ( 37,896 ) 6 (18) - ( 346,826 ) 6 (2) 9,000 - 21 431 ( 136 ) 1 ( 58,658 ) ( 190,342 ) 18,475 ( 17,659 ) ( 6,480 ) 11,247 ( 272,606 ) ( 69,060 ) ( 7,839 ) ( 1,652 ) 1,057 ( 1,428 ) 70,331 ( 57,982 ) - 23 ( 18,945 ) 19,269 28,371 54,988 199 ( 311 ) 360,511 144,291 187 432 38,977 20,235 ( 3,198 ) ( 4,864 ) ( 177,298 ) ( 21,859 ) 219,179 138,235

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries Consolidated cash flow statement

January 1 to December 31, 2021 and 2020

Cash flow from investing activities Acquisition of investment under the equity method Costs of property, plant and equipment acquired Proceeds from disposal of property, plant and equipment Acquisition of Intangible assets Decrease (increase) in deposits paid Net cash inflow (outflow) from investing activities Cash flow from financing activities Increase (decrease) in Shot-term borrowings Decrease in short-term bills payable Proceeds from long-term loan Re-payments of long-term borrowings Lease principal repayment Cash dividend distribution Cash dividends paid by subsidiaries - Changes in non-controlling interests Net cash inflow (outflow) from financing activities Effects of exchange rate fluctuation on cash Increase in cash and cash equivalents for the current period Opening balance of cash and cash equivalents Closing balance of cash and cash equivalents

Unit: NTD thousand Additional notes January 1 to December 31, 2021 January 1 to December 31, 2020 6 (5) ( $ 399,961 ) $ - 6 (23) ( 403,363 ) ( 191,612 ) 6 (23) - 1,059,906 ( 2,090 ) ( 1,371 ) 2,664 ( 1,895 ) ( 802,750 ) 865,028 6 (24) 150,000 ( 70,000 ) 6 (24) - ( 219,740 ) 6 (24) 1,200,000 600,000 6 (24) ( 600,000 ) ( 1,200,000 ) 6 (24) ( 2,712 ) ( 2,918 ) 6 (14) ( 116,340 ) ( 62,048 ) ( 333 ) ( 140 ) 630,615 ( 954,846 ) ( 419 ) ( 1,012 ) 46,625 47,405 148,625 101,220 $ 195,250 $ 148,625

Please refer to the notes enclosed in the consolidated financial reports that are an integral part of the consolidated financial statements.

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries Consolidated Notes to financial statements

2021 and 2020

Unit: NTD thousand (Except where otherwise stated)

1. Organization and operations

Chunghwa Chemical Synthesis and Biotech Co., Ltd. (hereinafter referred to as the Company) was established in Taiwan on May 19, 1964. Originally named as China Chemical Synthesis Industry Co., Ltd., the company was renamed to the current name at the shareholder meeting in 2003. The main areas of business of the Company and the subsidiaries (collectively referred to as the Group) include research, development, manufacturing and sales of active pharmaceutical ingredients. The Company was officially listed in the Taiwan Stock Exchange on December 20, 2010.

2. Financial reporting date and procedures

The Board of Directors approved the consolidated financial statements for publication on March 8, 2022.

3.

Application of new and revised standards and interpretation

(1) Effect of the adoption of new issuances of or amendments to International Financial Reporting Standards (“IFRS”) as endorsed by the Financial Supervisory Commission (“FSC”)

The following table summarizes the applicable newly released, corrected and amended standards and interpretations of the International Financial Reporting Standards recognized by the Financial Supervisory Commission in 2021.

The effective date announced by the New releases / amendments / revisions of the Standards and International Accounting Interpretations Standards Board Amendment to International Financial Reporting Standards (IFRS) #4 January 1, 2021 “The temporary exemption is equally applicable to the extension under IFRS #9.”

Phase II amendment to “Revolution to Interest Indicators” in January 1, 2021 International Financial Reporting Standards (IFRS) #9; IAS#39, IFRS#7, IFRS#4 and IFRS#16. Amendment to International Financial Reporting Standard 16: April 1, 2021 (Note) “Related Lease Concession due to COVID-19 after June 30, 2021”

Note: The Financial Supervisory Commission permits it to be applied on January 1, 2021 ahead of schedule.

The Group has assessed the aforementioned standards, interpretations, and interpretative announcements and has concluded that they have no material impact on the Group’s financial position and financial performance.

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(2) Effect of new issuances of or amendments to IFRS as endorsed by the FSC but not yet

adopted by the Company and subsidiaries

The following table summarizes the applicable newly released, corrected and amended standards and interpretations of the International Financial Reporting Standards recognized by the Financial Supervisory Commission in 2022.

The effective date announced by the New releases / amendments / revisions of the Standards and International Accounting Interpretations Standards Board Amendment to International Financial Reporting Standards (IFRS) #3 January 1, 2022 “Index to Conceptual Framework.” Amendment to International Financial Reporting Standards (IFRS) #16 January 1, 2022 “Real property, factories & equipment: Pricing prior to reach of anticipated state of use.” Amendment to International Financial Reporting Standards (IAS) #37 January 1, 2022 “Onerous contracts—the cost of fulfilling the contracts.” Improvements to IFRS 2018-2020 January 1, 2022

The Group has assessed the aforementioned standards, interpretations, and interpretative announcements and has concluded that they have no material impact on the Group’s financial position and financial performance.

(3) IFRS issued by IASB but not yet endorsed by the FSC

The newly released, revised and amended IFRS standards and interpretations by the IASB but not yet recognized by the FSC are summarized as follows:

The effective date announced by the New releases / amendments / revisions of the Standards and International Accounting Interpretations Standards Board Amendment to IFRS 10 and IAS 28 “The Assets Sales or Purchase To be determined by the between Investors and Their Affiliates or Joint Ventures” “International Accounting Standards Board (IASB). IFRS 17 “Insurance Contracts” January 1, 2023 Amendments to IFRS 17 “Insurance Contracts” January 1, 2023 Amendment to International Financial Reporting Standard 17: "Initial January 1, 2023 Application of IFRS 17 and IFRS 9―Comparative Information" Current or non-current classification of liabilities (Amendments to IAS 1) January 1, 2023 Amendment to International Financial Reporting Standards (IAS) #1 January 1, 2023 “Disclosure of accounting policies.” Amendment to International Financial Reporting Standards (IAS) #8 January 1, 2023 “Definition of accounting estimate.” Amendment to International Accounting Standard 12 “Deferred Tax January 1, 2023 related to Assets and Liabilities arising from a Single Transaction”

The Group has assessed the aforementioned standards, interpretations, and interpretative announcements and has concluded that they have no material impact on the Group’s financial position and financial performance.

4. Summary of significant accounting policies

The principal accounting polices applied in the preparation of these consolidated financial statements are set out below. These policies have been consistently applied to all the period presented, unless otherwise stated.

(1) Compliance Statement

These consolidated financial statements of the Group have been prepared in accordance with the “Regulations Governing the Preparation of Financial Statements by Securities Issuers”,

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International Financial Reporting Standards, International Accounting Standards, IFRIC Interpretations, and SIC Interpretations as endorsed by the FSC (collectively referred herein as the “IFRSs).

(2) Basis of preparation

1. Except for the following items, these consolidated statements have been prepared under the historical cost convention:

2. (1) Financial assets at fair value through other comprehensive Income

3. (2) The ascertained welfare assets recognized as the net amount of the pension fund assets minus the current value of the ascertained welfare obligations.

4. The preparation of financial statements in conformity with IFRS requires the use of certain critical estimates. It also requires management to exercise its judgment in the process of applying the accounting policies. The areas involving a higher degree of judgment or complexity, or areas where assumption and estimates are significant to the consolidated financial statements are disclosed in Note 5.

(3) Basis of consolidation

1. The basis of preparation for consolidated financial statements

2. (1) The Group incorporates all subsidiaries for the preparation of the consolidated financial statements. Subsidiaries are all entities (including structured entities) controlled by the Group. The Group controls an entity when the Group is exposed, or has rights, to variable returns from its involvement with the entity and has the ability to affect those returns through its power over the entity. Subsidiaries are incorporated into the consolidated financial statements from the date they are controlled by the Group and cease to be consolidated on the date it is no longer controlled by the Group.

3. (2) Inter-company transactions, balances and unrealized gains or losses on transactions between companies within the Group are eliminated from the consolidated financial statements. Subsidiaries’ financial statements are adjusted to align the accounting policies with those of the Group.

4. (3) The components of profit and loss and other comprehensive income are attributable to the owner of the parent company and non-controlling interests. The total comprehensive income is also attributable to the owner of the parent company and non-controlling interests, even if it results in a loss of non-controlling interests.

5. (4) Changes in a parent’s ownership interest in a subsidiary that do not result in the parent losing control of the subsidiary (transactions with non-controlling interests) are accounted for as equity transactions, i.e. transactions with owners in their capacity as owners. Any difference between the amount by which the non-controlling interests are adjusted and the fair value of the consideration paid or received is recognized directly in equity.

6. (5) When the Group loses control of a subsidiary, the Group re-measures any investment retained in the former subsidiary at its fair value. That fair value is regarded as the fair value on initial recognition of a financial asset or the cost on initial recognition of the associate or joint venture. Any difference between fair value and carrying amount is recognized in profit or loss. All amounts previously recognized in other comprehensive income in relation to the subsidiary are reclassified to profit or loss, on the same basis as would be required if the related assets or liabilities were disposed of. That is, when the Group loses control of a subsidiary, all gains or losses previously recognized in other comprehensive income in relation to the subsidiary should be reclassified from equity to profit or loss, if such gains or losses would be reclassified to profit or loss when the related assets or liabilities are disposed of.

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1. Subsidiaries included in the financial statements:

Subsidiaries included in the financial statements:
Investor Subsidiary name Nature of the operation Chunghwa Chemical Synthesis & Biotech Co., Ltd. PHARMAPORTS, LLC Trading of API drugs " CCSB HOLDING CO., LTD. Engaged in shareholding and reinvestment	Percentage of shareholdings December 31, 2021 December 31, 2020 98.00% 98.00% - -	Description
		Note

• Note 1: CCSB Holding Co., Ltd. reduced its capital in 2020 and remitted the investment amount NT$14,590 back to our Company on October 6, 2020 and completed the cancellation process on December 31, 2020. Since then, the Company discontinues to count it into the consolidated financial statement and enters it into other receivables instead. As of December 31, 2021, the other receivables amounted to NT$1,500.

• Subsidiary company not included in the consolidated financial statements are as follows: None

• Adjustments on subsidiary companies with different accounting periods: None.

• Significant limitations: None

• Subsidiaries of the Group with significant non-controlling interests: None.

- (4) Foreign currency translations

Items included in the financial statements of each of the Group’s entities are measured using the currency of the primary economic environment in which the entity operates (the “functional currency”). The consolidated financial statements are presented in New Taiwan Dollars, which is the Company’s functional currency.

1. Foreign Currency Transactions and Balances

2. (1) Transactions denominated in foreign currency are translated into a functional currency at the spot exchange rate on the date of the transaction or measurement. Foreign currency differences arising from translating such transactions are recognized in current profit or loss.

3. (2) The foreign currency asset or liability balances are revaluated based on spot exchange rate of the balance sheet date, and any exchange difference arising from the adjustment is included in the profit and loss for the year.

4. (3) Non-monetary assets and liabilities denominated in foreign currency held at fair value through profit or loss are re-translated at the exchange rates prevailing at the balance sheet date; their translation differences are recognized in current profit or loss ; Non-monetary assets and liabilities denominated in foreign currency held at fair value through other comprehensive income are re-translated at the exchange rates prevailing at the balance sheet date; their translation differences are recognized in other comprehensive income. However, non-monetary assets and liabilities denominated in foreign currency that are not measured at fair value are translated using the historical exchange rates at the date of the initial transaction.

5. (4) All foreign exchange gains and losses are presented in the statement of comprehensive income within “Other gains and losses”.

6. Translation of the financial statements of foreign operations

7. (1) The operating results and financial position of all the subsidiaries that have a functional currency different from the presentation currency are translated into the presentation currency as follows:

   • A. Assets and liabilities for each balance sheet presented are translated at the closing exchange rate at the date of that balance sheet.

   • B. Income and expenses for each statement of comprehensive income are translated at average exchange rates of that period; and

   • C. All resulting exchange differences are recognized in other comprehensive income.

8. (2) When the foreign operation partially disposed of or sold is a subsidiary, cumulative exchange differences that were recorded in other comprehensive income are

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proportionately transferred to the non-controlling interest in this foreign operation. However, if the Group retains partial interest in the former subsidiary after losing control of the former foreign subsidiary, such transactions should be accounted for as disposal of all interests in the foreign operation.

(5) Criteria for distinguishing Current or Non-Current on the Balance Sheet

1. Assets that meet one of the following criteria are classified as current assets:

2. (1) Assets arising from operating activities that are expected to be realized, or are intended to be sold or consumed within the normal operating cycle.

3. (2) Held mainly for the purpose of trading.

4. (3) Assets that are expected to be realized within twelve months from the balance sheet date.

5. (4) Cash and cash equivalents, excluding restricted cash and cash equivalents and those that are to be exchanged or used to pay off liabilities more than twelve month after the balance sheet date.

The Group classifies assets that do not meet any of the above criteria as non-current assets.

1. Liabilities that meet one of the following criteria are classified as current liabilities:

2. (1) Liabilities that are expected to be paid off within the normal operating cycle.

3. (2) Held mainly for the purpose of trading.

4. (3) Expected to be repaid within 12 months of the balance sheet date

5. (4) Liabilities for which the repayment date cannot be extended unconditionally to more than 12 months after the balance sheet date. Terms of a liability that could, at the option of the counterparty, result in its settlement by the issue of equity instruments do not affect its classification.

The Group classifies liabilities that do not meet any of the above criteria as non-current liabilities.

(6) Cash equivalents

Cash equivalents refer to short-term, highly liquid investments that are readily convertible to known amounts of cash and which are subject to an insignificant risk of changes in value. Time deposits that meet the definition above and are held for the purpose of meeting short-term cash commitments in operations are classified as cash equivalents.

(7) Financial assets at fair value through profit and loss

1. Refer to the financial assets that are not measured at amortized cost or are measured at fair value through other comprehensive income.

2. A regular way purchase or sale of financial assets is recognized and derecognized using either trade date or settlement date accounting.

3. The Group measures financial assets at fair value in initial recognition. The related transaction costs are recognized in profit and loss. These financial assets are subsequently re-measured and stated at fair value, and any changes in the fair value of these financial assets are recognized in profit or loss.

4. Once the right to receive dividends is confirmed, the Group recognizes the dividend income in profit or loss if the future economic benefits are expected to flow to the entity and the dividend can be measured reliably.

(8) Accounts receivable and notes

1. Refers to accounts and notes that have been unconditionally charged for the right to exchange the value of the consideration due to the transfer of goods or services.

2. The short-term accounts and notes receivable without bearing interest are subsequently measured at initial invoice amount as the effect of discounting is immaterial.

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(9) Impairment of Financial Assets

Financial assets measured at amortized cost, the Group, on each balance sheet date, considers all reasonable and supportable information (including forward-looking ones) and measures the loss allowance based on the 12-month expected credit losses for those that do not have their credit risk increased significantly since initial recognition. For those that have increased significantly since initial recognition, the loss allowance is measured based on the full lifetime expected credit losses. A loss allowance for full lifetime expected credit losses is also required for trade receivables that do not constitute a financing transaction.

(10) The de-recognition of financial assets

A financial asset is derecognized when the Group’s rights to receive cash flows from the financial assets have expired.

(11) The lessor’s lease transaction/business lease

Income from under an operating lease (net of any incentives given to the lessee) are recognized in profit or loss on a straight-line basis over the lease term.

(12) Inventory

Inventories are measured at the lower of cost or net realizable value, and the cost is determined by weighted-average method. The costs of finished and work in process goods include raw materials, direct labor, other direct costs and manufacturing-related expenses, excluding borrowing costs. At the end of year, inventories are evaluated at the lower of cost or net realizable value. The item by item approach is used in applying the lower of cost and net realizable value. Net realizable value is the estimated selling price in the ordinary course of business, less applicable variable costs of completion and selling expenses.

- (13) Investments in equity method associate companies

1. Associates are all entities over which the Group has significant influence but not control. In general, it is presumed that the investor has significant influence, if an investor holds, directly or indirectly 20 percent or more of the voting power of the investee. Investments in associates are accounted for under the equity method and are initially recognized at cost.

2. The Group’s share of its associates’ post-acquisition profits or losses is recognized in profit or loss in the current period, and its share of post-acquisition movements in other comprehensive income is recognized in other comprehensive income. When the Group’s share of losses in an associate equals or exceeds its interest in the associate (including any other unsecured receivables), the Group does not recognize further losses, unless it has incurred statutory/constructive obligations or made payments on behalf of the associate.

3. When there is equity change in non-profit and loss and other consolidated profit and loss occurring to the affiliated enterprises that do not affect the shareholding of the affiliated enterprises, the Group will have the equity change recognized as “additional paid-in capital” proportionally to the shareholding ratio.

4. Unrealized gains on transactions between the Group and its associates are eliminated to the extent of the Group’s interest in the associates. Unrealized losses are also eliminated unless the transaction provides evidence of an impairment of the asset transferred. Accounting policies of associates have been adjusted where necessary to ensure consistency with the polices adopted by the Group.

5. When the Group disposes of its investment in an associate and loses significant influence over this associate, the amounts previously recognized in other comprehensive income in relation to the associate are accounted for on the same basis as direct disposal of related assets or liabilities, that is, profit or loss previously recognized in other comprehensive income are reclassified to profit or loss when related assets or liabilities are disposed of. When the Group loses significant influence over the associate, the aforesaid profit or loss is

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reclassified from retained earnings to profit or loss. If it still retains significant influence over the associate, then the amounts previously recognized in other comprehensive income in relation to the associate are reclassified to profit or loss proportionately in accordance with the aforementioned approach.

(14) Property , plant, and equipment

1. Property, plant and equipment are initially recorded at cost. Borrowing costs incurred during the construction period are capitalized.

2. Subsequent costs are included in the asset’s carrying amount or recognized as a spate asset, as appropriate, only when it is probable that future economic benefits associated with the item will flow to the Group and the cost of the item can be measured reliably. The carrying amount of the replaced part is derecognized. All other repairs and maintenance are charged to profit or loss during the period in which they are incurred.

3. Land is not depreciated. Other property, plant and equipment apply cost model and are depreciated using the straight-line method to allocate their cost over their estimated useful lives. Each part of an item of property, plant, and equipment with a cost that is significant in relation to the total cost of the item must be depreciated separately.

4. The assets’ residual values, useful lives and depreciation methods are reviewed, and adjusted if appropriate, at each balance sheet date. If expectations for the assets’ residual values and useful lives differ from previous estimates or the patterns of consumption of the assets’ future economic benefits embodied in the assets have changed significantly, any change is accounted for as a change in estimate under IAS 8, “Accounting Policies, Changes in Accounting Estimates and Errors”, from the date of change. The estimated useful lives of property, plant and equipment are as follows:

Buildings and structures 2 years ~ 60 years Machinery equipment 1 years ~ 43 years Transport equipment 2 years ~ 34 years Other equipment 5 years ~ 18 years

(15) The lessee’s lease transaction-right-of-use assets/lease liabilities.

1. Lease assets are recognized on the day of the available for use by the Group as right-of-use assets and lease liabilities. If the lease contract is a short-term lease or a lease of an underlying asset with low-value, lease payment is recognized using the straight-line method as an expense during the period of lease based.

2. The lease liability on the first day of lease is recognized at the present value after unpaid lease payments are converted into cash according to the Group’s incremental borrowing interest rate. Lease payments include fixed payments deducted by any lease incentives received. According to the follow-up interest method and measurements by the amortized cost method, interest incurring during the period of lease is provisioned. In case of changes in the period of lease or lease payments not attributed to contract modifications, the lease liability will be re-evaluated, and the remeasurement will be used to readjust the right-of-use asset.

3. The right-of-use asset is recognized by cost on the starting day of lease. The costs include:

4. (1) The original measured amount of lease liability;

5. (2) Any original direct costs incurred;

The cost model is adopted for subsequent measurements. Either the end of the durability of right-of-use assets or the end of the period of lease incurring earlier will be provisioned as depreciation fees. When re-evaluating lease liability, the right-of-use asset will readjust any remeasurements of lease liability.

(16) Investment property

Investment properties are initially measured at cost and may be subsequently measured using

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a cost model.

(17) Intangible assets

Computer software is recognized at cost and is amortized over the estimated useful life of 1 to 3 years according to the straight-line method.

(18) Losses in non-financial asset

The Group assesses at each balance sheet date the recoverable amounts of those assets where there is an indication that they are impaired. An impairment loss is recognized for the amount by which the asset’s carrying amount exceeds its recoverable amount. Recoverable amount refers to an asset’s fair value less the cost of disposal or the useful value, whichever is the higher. Except for goodwill, when the impairment of assets recognized in prior period is non-existent or reduced, the impairment loss should be reversed. However, the increased book value of the asset due to the reversed impairment loss may not exceed the book value net of depreciation or amortization before recognizing impairment loss.

(19) Loans

Borrowings are recognized initially at fair value, net of transaction costs incurred. Borrowings are subsequently stated at amortized cost; any difference between the proceeds (net of transaction costs) and the redemption value is recognized in profit or loss over the period of the borrowings using the effective interest method.

(20) Notes and accounts payable

1. Refers to debts incurred as a result of the purchase of raw materials, goods or services and the notes payable due to business and non-business purposes.

2. The short-term accounts and notes payable without bearing interest are subsequently measured at initial invoice amount as the effect of discounting is immaterial.

(21) De-recognition of financial liabilities

The Group derecognizes a liability when the obligation under the liability specified in the contract is discharged or cancelled or expires.

(22) Financial assets and liabilities written-off against each other

Recognized financial liabilities and assets are offset and the net amount reported in the balance sheet when there is a legally enforceable right to offset the recognized amounts and there is an intention to settle on a net basis or realize the asset and settle the liability simultaneously.

(23) Employee benefits

1. Short-term employee benefits

Short-term employee benefits are measured at the discounted amount of the benefits expected to be paid in respect of service rendered by employees and are recognized as expenses in the period when the employees render service.

1. Pension

2. (1) Defined contribution plan

For defined contribution plans, the contributions are recognized as pension expenses when they are due on an accrual basis. Prepaid contributions are recognized to the extent of a cash refund or a reduction in the future payments.

• (2) Defined benefit plan

• A. Net obligation under a defined benefit plan is defined as the present value of an

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amount of pension benefits that employees will receive on retirement for their services with the Group in current period or prior periods. The liability recognized in the balance sheet in respect of defined benefit pension plans is the present value of the defined benefit obligation at the balance sheet date less the fair value of plan assets. The net defined benefit obligation is calculated annually by independent actuaries using the projected unit credit method. The rate used to discount is determined by using interest rates of government bonds (at the balance sheet date) instead.

• B. Re-measurements arising on defined benefit plans are recognized in other comprehensive income in the period in which they arise and are recoded as retained earnings.

• C. The expense associated with prior service cost is recognized immediately as a profit or loss.

• Remunerations for employees and directors

Remunerations for employees and directors are recognized as expense and liability, provided that such recognition is required under legal or constructive obligation and those amounts can be reliably estimated. If the accrued amounts for employees’ compensation and remuneration to directors and supervisors are different from the actual distributed amounts, the differences should be recognized based on the accounting for changes in estimates. If employee compensation is distributed by shares, the Group calculates the number of shares based on the closing price at the previous day of the board meeting resolution.

(24) Income tax

1. The tax expense for the period comprises current and deferred tax. Tax is recognized in profit or loss, except to the extent that it relates to items recognized in other comprehensive income or items recognized directly in equity, in which cases the tax is recognized in other comprehensive income or equity.

2. The current income tax charge is calculated on the basis of the tax laws enacted or substantively enacted at the balance sheet date in the countries where the Group operates and generates taxable income. Management periodically evaluates positions taken in tax returns with respect to situations in accordance with the applicable tax regulations. An additional tax is levied on the unappropriated retained earnings and is recorded as income tax expense in the year the stockholders resolve to retain the earnings.

3. Deferred income tax is recognized, using the balance sheet liability method, on temporary differences arising between the tax bases of assets and liabilities and their carrying amounts in the consolidated financial statements. However, the deferred income tax is not accounted for if it arises from initial recognition of goodwill or of an asset or liability in a transaction other than a business combination that at the time of the transaction affects neither accounting nor taxable profit or loss. Deferred income tax is provided on temporary differences arising on investments in subsidiaries and associates, except where the timing of the reversal of the temporary difference is controlled by the Group and it is probable that the temporary difference will not reverse in the foreseeable future. Deferred income tax is determined using tax rates (and laws) that have been enacted or substantially enacted as of the balance sheet date and are expected to apply when the related deferred income tax asset is realized or the deferred income tax liability is settled.

4. Deferred income tax assets are recognized only to the extent that it is probable that future taxable profit will be available against which the temporary differences can be utilized. At each balance sheet date, unrecognized and recognized deferred income tax assets are reassessed.

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1. Current income tax and liabilities are offset and the net amount is reported in the balance sheet when there is a legally enforceable right to offset the recognized amounts and there is an intention to settle on a net basis or realize the asset and settle the liability simultaneously. Deferred income tax assets and liabilities are offset on the balance sheet when the entity has the legally enforceable right to offset current tax assets against current tax liabilities and they are levied by the same taxation authority on either the same entity or different entities that intend to settle on a net basis or realize the asset and settle the liability simultaneously.

(25) Dividends

Dividends distributed to shareholders of the Company are recognized in the financial statements when the shareholder meeting resolves to distribute dividends, and the cash dividends are recognized as liabilities.

(26) Recognition of revenue

1. Product sales

• (1)The Group manufactures and sells API-related products. The sales revenue is recognized when products are delivered to customers who have discretionary power in channels and prices of products sold and the Group has no outstanding performance obligations which may affect customers’ acceptance of products. The delivery of products is considered occurs when the products are shipped to the designated locations and the risks of obsolescence and loss have been transferred to customers who accept the products under sales contracts, or when there is objective evidence showing that all acceptance criteria have been met.

• (2) Account receivables are recognized when goods are delivered to customers. Since the Group has unconditional rights to the contract price from that point in time, only the passage of time is required before the payment is due.

2. Labor revenue

• (1) The Group provides commissioned bio drug testing and other related services. Labor service income is recognized as income during the period of financial reporting on services provided to customers. Revenues from fixed price contracts are recognized based of the proportion of services provided in all services provided as of the balance sheet date. The percentage of service completion is based on the proportion of actual costs incurred in the total costs. The customer shall pay contract prices according to the payment time agreed. When services provided by the company exceed the customer’s accounts payable, they are recognized as contract assets; if the customer’s accounts payable exceeds the services provided by the company, they are recognized as contract liability.

• (2) The Group’s estimates of revenues, costs, and degree of work completion are subject to amendments as circumstances change. Any increase or decrease in estimated income or cost due to changes in estimates shall be reflected in profit or loss during the period in which the circumstances leading to the amendments are known to management.

(27) Operating segments

The operating segment information and the internal management reports submitted to the mainly operational decision makers are consistent in the way of reporting. The chief operating decision-maker is responsible for allocating resources and assessing performance of the operating segments.

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5. Main source of significant accounting judgment, estimates and assumptions uncertainty

The preparation of these consolidated financial statements requires management to make critical judgments in applying the Group’s accounting policies and make critical assumptions and estimates based on the expectation of future events that are believed to be reasonable under the circumstances at the end of the reporting period. The resulting accounting estimates might be different from the related actual results, the judgments and estimates are continually evaluated and adjusted based on historical experience and other factors. Such assumptions and estimates have a significant risk of causing a material adjustment to the carrying amounts of assets and liabilities within the next financial year. Critical accounting judgments, estimates and key sources of assumption uncertainty are explained as follows:

(1) Critical judgments concerning the application of accounting policies

None.

• (2) Critical accounting estimates and assumptions

Evaluation of inventory

The Group measures the normal sales of inventories by the lower of cost and net realizable value. For inventories that have existed longer than a certain period of time and are obsolete and damaged, net realizable value of each inventory is identified to be recognized as a loss. Therefore, the Group must use its best judgments and estimates to determine the net realizable value of inventory at the balance sheet date. Due to the stricter verification of active pharmaceutical ingredients and the lengthening time required to obtain drug licenses, the disposal of inventory is below expectation, resulting in the loss from inventory depreciation or the higher risk of inventory obsolescence. The Group assesses on the balance sheet date the inventory due to normal wear and tear, obsolescence or without market sales value and reduces the inventory cost to net realizable value. The inventory assessment may experience significant changes due to fluctuations in the net realizable value of future products. As of December 31, 2021, the book balance of the Group’s inventories is NT$753,850.

6. Summary of significant accounting titles

(1) Cash and cash equivalents

Cash on hand and petty cash Checking accounts and demand deposits Cash equivalents- Short-term bills	$	December 31, 2021 513 194,737 -	$	December 31, 2020 418 99,791 48,416 148,625
	$	195,250	$

1. The financial institutions that the Group deals with are with good credit quality; also, the Group deals with a number of financial institutions to diversify credit risk; therefore, the possibility of default is very unlikely.

2. None of the Group’s cash and cash equivalents pledged to others as collateral.

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(2) Financial assets at fair value through profit and loss

Item	December 31, 2021	December 31, 2021	December 31, 2020	December 31, 2020
Non-current items:
Financial assets mandatorily
measured at fair value through
profit or loss
China Development Biomedical
Venture Capital (limited company)	$	21,000	$	30,000
Evaluation adjustment		5,726		2,456
	$	26,726	$	32,456
1. Financial assets at fair value through	profit and loss is detailed as		follows:
	2021			2020
Financial assets mandatorily
measured at fair value through profit
or loss
Equity instruments	$	3,270	$	4,296
2. In March 2021, the share value returned upon capital decrease for			financial	assets measured
at fair value through profits or losses	invested in by the	Group totaled $9,000.

(3) Note receivable and accounts receivable

December 31, 2021 Notes receivable $ 480 Less: Allowance for losses - $ 480 Accounts receivable $ 374,534 Less: Allowance for losses ( 18,611) $ 355,923 1. Aging of accounts receivable and notes receivable is as follows: (1) Notes receivable December 31, 2021 Not overdue $ 480 (2) Accounts receivable December 31, 2021 Not overdue $ 319,258 Up to 30 days 36,931 Over 90 days 18,345 $ 374,534	December 31, 2021 Notes receivable $ 480 Less: Allowance for losses - $ 480 Accounts receivable $ 374,534 Less: Allowance for losses ( 18,611) $ 355,923 1. Aging of accounts receivable and notes receivable is as follows: (1) Notes receivable December 31, 2021 Not overdue $ 480 (2) Accounts receivable December 31, 2021 Not overdue $ 319,258 Up to 30 days 36,931 Over 90 days 18,345 $ 374,534	December 31, 2021 480 -	$
		480	$
		374,534 18,611) 355,923	$ (
			$
			$
	December 31, 2021 $ 319,258 36,931 18,345 $ 374,534

The aforementioned aging analysis is based on the overdue days.

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1. The accounts receivables and bills receivable balance in December 31, 2021 and 2020 were generated from the client contract. The accounts receivables balance and allowance loss in the client contract as of January 1, 2020 amount to NT$125,879 and NT$266 respectively.

2. While not considering the collaterals or other credit enhancements, the notes and accounts receivable held by the Group had the maximum exposure of credit risk at NT$356,403 and NT$315,954, respectively, as of December 31, 2021 and 2020.

3. The Group does not hold any collaterals.

4. Please see Note 12 (2) for the credit quality of the accounts receivable and notes receivable.

5. (4) Inventory

Raw materials Work in process Finished products Raw materials Work in process Finished products	$	Cost 366,960 71,866 396,099 834,925 Cost 188,368 77,104 282,773 548,245	December 31, 2021 Price loss allowance ($ 33,034) $ ( 471) ( 47,570) ($ 81,075) $ December 31, 2020 Price loss allowance ($ 21,153) $ ( 550) ( 45,298) ($ 67,001) $	December 31, 2021 Price loss allowance ($ 33,034) $ ( 471) ( 47,570) ($ 81,075) $ December 31, 2020 Price loss allowance ($ 21,153) $ ( 550) ( 45,298) ($ 67,001) $	Book value 333,926 71,395 348,529 753,850 Book value 167,215 76,554 237,475 481,244
	$
	$ $
			($ 21,153) ( 550) ( 45,298) ($ 67,001)
				$

The Group’s current inventory cost recognized as expenses:

Cost of inventory sold Loss of price decline of inventory and obsolescence loss Proceeds from sale of scraps.	$ (	2021 957,369 28,964 3,019) 983,314	$ (	2020 839,956 14,899 3,179) 851,676
	$		$

(5) Investments accounted for by the equity method

Affiliate business: China Chemical & Pharmaceutical Co., Ltd. 1. Affiliate business	December 31, 2021 $ 1,032,860	December 31, 2020 $ 511,434

(1) The basic information of the Group’s main affiliates is shown as follows:

Company Name China Chemical & Pharmaceutical Co., Ltd.	Main places	Ratio of Shareholding Ratio of Shareholding Type of affiliation December 31, 2021 December 31, 2020 14.11% 8.49% Strategic investment	Measurement Equity method
	of business operations Taiwan

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• (2) The aggregated information of the Group’s main affiliates is shown as follows: Balance Sheet

BalanceSheet
Current assets Non-Current assets Current liabilities Non-current liabilities Total net assets Book value of affiliates	$ ( (	China Chemical & Pharmaceutical Co., Ltd. December 31, 2021 December 31, 2020 3,193,213 $ 3,475,791 7,988,514 7,093,226 1,512,912) ( 1,874,262) 1,914,705) ( 2,103,576)
	$	7,754,110	$	6,591,179
	$	1,032,860	$	511,434

Comprehensive income statement

Income Current net profits from continuing operations Other comprehensive income (net after tax) Total comprehensive income for the period Stock dividends collected from affiliates	$	China Chemical & Pharmaceutical Co., Ltd. 2021 2020 3,407,463 $ 3,857,241	China Chemical & Pharmaceutical Co., Ltd. 2021 2020 3,407,463 $ 3,857,241	China Chemical & Pharmaceutical Co., Ltd. 2021 2020 3,407,463 $ 3,857,241
			2021 3,407,463 $
	$		517,508 $ 942,413	557,232 366,087
	$		1,459,921 $	923,319
	$		38,977 $	20,235

1. Profit and loss of associates recognized by using equity method:

China Chemical & Pharmaceutical Co., Ltd.	$	2021 50,100	$	2020 37,896

1. In 2021, the Group obtained NT$399,961 equity from China Chemical & Pharmaceutical Co., Ltd. in the open market.

2. The Group’s investment in China Chemical & Pharmaceutical has a public offer of which the fair value were NT$952,504 and NT$508,987 as of December 31, 2021 and 2020, respectively.

3. The Group holds up to 14.11% of the total shares of China Chemical & Pharmaceutical Co., Ltd. as the largest single shareholder. Given the facts that the Group lacks substantial capability to dominate the relevant events as indicated through the participation by other shareholders in that company and the voting powers in major motions, it is judged that the Group does not possess control power but only has influence toward that company.

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(6) Property , plant, and equipment

January 1 Cost Accumulated depreciation and impairment 2021 January 1 Additions Reclassification Depreciation Net exchange differences December 31 December 31 Cost Accumulated depreciation and impairment	$	Land 741,400 - (	Buildings and	Buildings and	$ (	Machinery equipment 1,172,957 888,583)	$ (	2021 Transport equipment 7,448 5,950) 1,498	Other equipment $ 580,181 ( 409,306) $ 170,875	Uncompleted construction and equipment pending inspection $ 112,289 - $ 112,289 $ 112,289 404,269 ( 390,115) - - $ 126,443 $ 126,443 - $ 126,443	Total $ 3,288,531 ( 1,749,280) $ 1,539,251 $ 1,539,251 454,638 - ( 127,733) ( 4) $ 1,866,152 $ 3,725,884 ( 1,859,732) $ 1,866,152
			$	structures 674,256 445,441)
	$	741,400	$	228,815	$	284,374	$			$
	$	741,400 - - - ( -	$	228,815 17,727 134,124 25,253) -	$ (	284,374 14,160 241,528 66,750) -	$ (	1,498 860 - 457) -	$ 170,875 17,622 14,463 ( 35,273) ( 4) $ 167,683	$ (
	$	741,400	$	355,413	$	473,312	$	1,901		$
	$	741,400 - (	$	826,107 470,694)	$ (	1,414,963 941,651)	$ (	8,121 6,220) 1,901	$ 608,850 ( 441,167) $ 167,683	$
	$	741,400	$	355,413	$	473,312	$			$

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Land January 1 Cost $ 1,454,384 Accumulated depreciation and impairment - $ 1,454,384 2020 January 1 $ 1,454,384 Additions - Disposition ( 712,984) Reclassification (Note) - Depreciation - Net exchange differences - December 31 $ 741,400 December 31 Cost $ 741,400 Accumulated depreciation and impairment - $ 741,400	Buildings and structures $ 662,864 ( 421,831) $ 241,033 $ 241,033 5,960 - 5,433 ( 23,611) - $ 228,815 $ 674,256 ( 445,441) $ 228,815	$ (	Machinery equipment 1,128,088 833,042) 295,046 295,046 5,222 96) 50,481 66,279) - 284,374 1,172,957 888,583) 284,374	$ (	2020 Transport equipment 6,899 6,624) 275 275 1,421 - - 198) - 1,498 7,448 5,950) 1,498	Other equipment $ 553,846 ( 381,544) $ 172,302 $ 172,302 30,229 - 4,970 ( 36,622) ( 4) $ 170,875 $ 580,181 ( 409,306) $ 170,875	$	Uncompleted construction and equipment pending inspection 17,268 - 17,268 17,268 156,186 - 61,165) - - 112,289 112,289 - 112,289	Total $ 3,823,349 ( 1,643,041) $ 2,180,308 $ 2,180,308 199,018 ( 713,080) ( 281) ( 126,710) ( 4) $ 1,539,251 $ 3,288,531 ( 1,749,280) $ 1,539,251
	$	$		$			$
	$ (	$ ( (		$ (			$ (
	$	$		$			$
	$ (	$ (		$ (			$
	$	$		$			$

Note: The term reclassification is an act to transfer out onto “intangible assets.”

The Group executed a contract on land transaction with Lian Hwa Foods Corporation on May 14, 2020. The aggregate total price under the transaction amounted to NT$1,063,953. After deducting essential transaction cost of NT$4,247, the benefit from the transaction amounted to NT$346,722. The ownership transfer registration was completed in June 2020.

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(7) Investment property

Land cost	$	December 31, 2021 10,700	$	December 31, 2020 10,700

1. Rental income and direct operating expenses of investment properties:

Rental income of investment properties Direct operating expenses incurred in investment properties that have rental income in the current period	2021 $ 800	2020 $ 824
	$ 48	$ 48

1. The fair value of investment properties held by the Group for the years ended December 31, 2021 and 2020 was NT$70,305 and NT$50,239, respectively, based on the transaction prices of the adjacent lands.

(8) Shot-term borrowings

In the Group, short-term loans were nonexistent as of December 31, 2020. As of December 31, 2021, the short-term loan fact was as follows:

Loans nature	December 31, 2021	Interest rate collars	Collateral
Bank loan
Credit loan	$ 150,000	0.80%~0.83%	None

(9) Other payable

Remuneration to employees and directors and supervisors payable Equipment payables Salary and bonus payables Commission payable Repair fees payable Others	$	December 31, 2021 52,390 94,544 74,224 11,458 5,643 59,282	$	December 31, 2020 46,996 13,183 74,628 12,184 7,103 33,592
	$	297,541	$	187,686

- (10) Long term borrowings

Bank loan Credit loan Interest rate collars	$	December 31, 2021 600,000	$ –	December 31, 2020 -
	1.13%~1.35%

The one-time repayment of credit loan is due in 2023.

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(11) Pension

1. (1) The Company has a defined benefit pension plan in accordance with the “Labor Standards Act”, covering all regular employees’ service years prior to the enforcement of the Labor Pension Act on July 1, 2005 and service years thereafter of employees who chose to continue to be subject to the pension mechanism under the Law. When an employee meets the requirements of retirement, the payment of pension is based on service years and the average salary of the six months prior to retirement, with services within 15 years accumulating 2 basis points per year, and service years beyond 15 years accumulating 1 basis point per year up to a maximum of 45 basis points. The company provisions 5% of total monthly salary to the pension fund in the name of the Pension Supervisory Committee at the Bank of Taiwan. In addition, the Company has the labor pension reserve account balance referred to in the preceding paragraph estimated at the end of each fiscal year. If the account balance is insufficient to pay pension benefit to the employees who qualify for retirement within next year for the pension benefit calculated in the preceding paragraph, the Company will have the spread amount appropriated in a lump sum before the end of March next year.

2. (2) The amounts recognized in the balance sheet are as follows:

estimated at the end of each fiscal year. If the account balance is insufficient to pay pension benefit to the employees who qualify for retirement within next year for the pension benefit calculated in the preceding paragraph, the Company will have the spread amount appropriated in a lump sum before the end of March next year. The amounts recognized in the balance sheet are as follows:	estimated at the end of each fiscal year. If the account balance is insufficient to pay pension benefit to the employees who qualify for retirement within next year for the pension benefit calculated in the preceding paragraph, the Company will have the spread amount appropriated in a lump sum before the end of March next year. The amounts recognized in the balance sheet are as follows:	estimated at the end of each fiscal year. If the account balance is insufficient to pay pension benefit to the employees who qualify for retirement within next year for the pension benefit calculated in the preceding paragraph, the Company will have the spread amount appropriated in a lump sum before the end of March next year. The amounts recognized in the balance sheet are as follows:	estimated at the end of each fiscal year. If the account balance is insufficient to pay pension benefit to the employees who qualify for retirement within next year for the pension benefit calculated in the preceding paragraph, the Company will have the spread amount appropriated in a lump sum before the end of March next year. The amounts recognized in the balance sheet are as follows:	estimated at the end of each fiscal year. If the account balance is insufficient to pay pension benefit to the employees who qualify for retirement within next year for the pension benefit calculated in the preceding paragraph, the Company will have the spread amount appropriated in a lump sum before the end of March next year. The amounts recognized in the balance sheet are as follows:	estimated at the end of each fiscal year. If the account balance is insufficient to pay pension benefit to the employees who qualify for retirement within next year for the pension benefit calculated in the preceding paragraph, the Company will have the spread amount appropriated in a lump sum before the end of March next year. The amounts recognized in the balance sheet are as follows:	estimated at the end of each fiscal year. If the account balance is insufficient to pay pension benefit to the employees who qualify for retirement within next year for the pension benefit calculated in the preceding paragraph, the Company will have the spread amount appropriated in a lump sum before the end of March next year. The amounts recognized in the balance sheet are as follows:
December 31, 2021 December 31, 2020 Present value of the defined benefit obligations ($ 117,792) ($ 115,828) The fair value of plan assets 141,770 139,113 Net defined benefit assets $ 23,978 $ 23,285 (Recognized as Other non-current assets) Changes in net defined benefit assets are as follows: Present value of the defined benefit obligations The fair value of plan assets Net defined benefit assets 2021 Balance at January 1 ($ 115,828) $ 139,113 $ 23,285 Current service cost ( 1,326) - ( 1,326) Interest (expense) income ( 342) 416 74 ( 117,496) 139,529 22,033 Revaluation amount: Return on plan assets (excluding amounts included in interest income or expense) - 2,046 2,046 The effect of changes in financial assumptions 3,508 - 3,508 Experience adjustments ( 3,804) - ( 3,804) ( 296) 2,046 1,750 The appropriation of pension fund - 195 195 Balance at December 31 ($ 117,792) $ 141,770 $ 23,978
					assets 139,113 $ - ( 416	assets 23,285 1,326) 74
	(		117,496)		139,529	22,033
	(		- 3,508 3,804)		2,046 - - (	2,046 3,508 3,804) 1,750
	(		296)		2,046
			-		195	195
	($		117,792)	$	141,770 $	23,978

• (3) Changes in net defined benefit assets are as follows:

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2020 Balance at January 1 ($ Current service cost ( Interest (expense) income ( ( Revaluation amount: Return on plan assets (excluding amounts included in interest income or expense) The effect of changes in financial assumptions ( Experience adjustments ( ( The appropriation of pension fund Balance at December 31 ($	($ ( (	Present value of the defined benefit obligations 109,160) 1,073) 728) 110,961) - 3,674) 1,193) 4,867) - 115,828)	Present value of the defined benefit obligations 109,160) 1,073) 728) 110,961) - 3,674) 1,193) 4,867) - 115,828)	The fair value of plan assets $ 131,261 - 891 132,152 4,623 - - 4,623 2,338 $ 139,113	Net defined benefit assets $ 22,101 ( 1,073) 163 21,191 4,623 ( 3,674) ( 1,193) ( 244) 2,338 $ 23,285	Net defined benefit	Net defined benefit
							assets 22,101 1,073) 163 21,191 4,623 3,674) 1,193) 244) 2,338 23,285
	(
					( (
	(				(
	($			$	$

(4) The Bank of Taiwan was commissioned to manage the Fund of the Company’s defined benefit pension plan in accordance with the Fund’s annual investment and utilization plan and the “Regulations for Revenues, Expenditures, Safeguard and Utilization of the Labor Retirement Fund” (Article 6: The scope of utilization for the Fund includes deposit in domestic or foreign financial institutions, investment in domestic or foreign listed, over-the-counter, or private placement equity securities, investment in domestic or foreign real estate securitization products, etc.). For the use of this fund, the minimum earnings distribution every year shall not be for an amount less than the income calculated in accordance with the local bank’s two-year time deposit rate; also, the insufficient fund, if any, should be made up by the National Treasury with the approval of the competent authorities. Since the Company is not entitled to participating in the operation and management of the Fund, the classification of the fair value of plant asset cannot be disclosed in accordance with International Accounting Standards No. 19, paragraph 142. The composition of fair value of plan assets as of December 31, 2021 and 2020 is given in the Annual Labor Retirement Fund Utilization Report announced by the government.

(5) Assumptions for the actuation of pension funds are summarized as follows:

Discounted rate Future salary increases rate	2021 0.70% 2.00%	2020 0.30% 2.00%

Assumptions regarding future mortality experience are set based on actuarial advice in accordance with the published statistics and experience in the 6th Taiwan Standard Ordinary Experience Mortality Table.

The present value of the defined benefit obligations affected by the changes in the actuarial assumptions is analyzed as follows:

December 31, 2021 The impact on the present value of the defined benefit obligations ($ December 31, 2020 The impact on the present value of the defined benefit obligations ($	Discounted rate Increase by 0.25% Decrease by 0.25% 2,132) $ 2,197 2,319) $ 2,395	$	Future salary Increase by 0.25% 2,163 2,348	Future salary	increases rate Decrease by 0.25% $ 2,110 ($ 2,286)	increases rate Decrease by 0.25% $ 2,110 ($ 2,286)	increases rate Decrease by 0.25% $ 2,110 ($ 2,286)
					$
							0.25% 2,110 2,286)
		$			($

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The sensitivity analysis above analyzes the impact from changing one of the assumptions while others remain constant. In practice, many changes in assumptions may be mutually interactive. The sensitivity analysis is consistent with the method adopted for calculating the net pension liability on the balance sheet.

  - (6) The Company applied on December 7, 2020 for suspension from appropriation of labor pension reserve. The Company has been approved for suspension from appropriation starting from fiscal year 2021.

1. (1) The Company has a retirement policy with a defined pension contribution plan regulated in accordance with the “Labor Pension Act” for the employees of Taiwan nationality since July 1, 2005. The Company has established a defined contribution pension plan (the “New Plan”) under the “Labor Pension Act” covering all regular employees. Under the New Plan, the Company contributes monthly an amount based on 6% of the employees’ monthly salaries and wages to an employee’s individual pension account at the Bureau of Labor Insurance. The payment of pension benefits is based on an employee’s individual pension fund account and the cumulative profit in such account, and employees can choose to receive such pension benefits monthly or in one lump sum.

   • (2) Pharmaports, LLC follows the retirement insurance system in the US and has an internal policy determining the allocation of pensions. Every month, a certain percentage of the local employees’ salary is allocated to the pension fund.

   • (3) The pension costs under the defined contribution pension plans of the Group for the 2021 and 2020 were NT$9,856 and NT$9,102, respectively.

2. (12) Share capital

3. As of December 31, 2021, the Company’s authorized capital was $1,600,000, consisting of 160,000 thousand shares of ordinary stock, and the paid-in capital was NT$775,600 with a par value of $10 (in dollars) per share. All issued capital of the Company were paid up.

4. The number of the Company’s outstanding ordinary shares was 77,560 thousand as of 2021 and 2020.

5. The affiliation of the Company held 19,245 thousand shares and 17,331 thousand shares, respectively of the Company as of December 31, 2021 and 2020.

6. (13) Capital reserve

According to the Company Act, capital reserves from premium income for issuing shares over face values and gift income, not only can offset losses, it can also issue new shares or cash according to the original shareholding when there is no accumulated losses in the company. Further, the Securities and Exchange Act requires that the amount of capital surplus to be capitalized, as above, should not exceed 10% of paid-in capital each year. When the retained earnings of a company is not enough to offset capital losses, the capital reserves cannot be applied.

(14) Retained earnings

1. According to the Company’s articles of incorporation, the dividend policy considers the Company’s future capital needs and long-term financial planning and meets the shareholders’ demand for cash inflows. The current year’s earning, if any, shall first be used to offset prior years’ operating losses and pay all taxes, and then 10% of the remaining amount shall be set aside as legal reserve. Special reserve shall also be allocated. If there is still surplus, it can be put together with the accumulated undistributed surplus of the previous year as the surplus available this year for distribution. Part of it can be retained, depending on the Company’s business needs for the year, before being distributed to

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shareholders. Cash dividends shall not be less than 50% of the shareholder dividend given, but when the cash dividend is calculated to be less than $0.1 per share, it can be given in the form of stock dividend.

1. Except for covering accumulated deficit or issuing new stocks or cash to shareholders in proportion to their share ownership, the legal reserve shall not be used for any other purpose. The use of the legal reserve for the issuance of stocks or cash to shareholders in proportion to their share ownership is permitted, provided that the distribution of the reserve is limited to the portion in excess of 25% of the Company’s paid-in capital.

2. (1) In accordance with the regulations, the Company shall set aside special reserve from the debit balance on other equity items at the balance sheet date before distributing earnings. When debit balance on other equity items is reversed subsequently, the reversed amount could be included in the distributable earnings.

3. (2) When adopting IFRSs for the first time, refer to Jin-Guan-Zheng-Fa-Zi Document #1010012865 on special reserve. The Company will conduct a reversal of the originally allocated special reserve when using, disposing of or reclassifying assets.

4. (1) The appropriations of 2020 and 2019 earnings had been resolved at the shareholders’ meeting on July 1, 2021 and May 29, 2020, respectively. Details are summarized below:

below:	below:
Legal earnings reserve $ Cash dividend $		Amount 54,786 116,340	2020 Dividends per share ($) $ $ 1.5 $			Amount 11,885 62,048	2019 Dividends per share ($) $ 0.8
				($) $ 1.5				share ($) 0.8
	$	171,126			$	73,933

• (2) The appropriations of 2021 earnings had been proposed by the Board of Directors on March 8, 2022. Details are summarized below:

March 8, 2022. Details are summarized below:
Legal earnings reserve Cash dividend	$	Amount 47,598 100,828	2021 Dividends per share ($) $ 1.3
				share ($) 1.3
	$	148,426

The aforementioned distribution of earnings of 2021 has not been passed in the shareholders’ meeting.

(15) Operating revenues

Revenue from Contracts with Customers	$	2021 1,934,702	$	2020 1,543,589

1. Segmentation of revenue from contracts with customers

The Group’s revenues are generated from goods and labor services gradually transferred with time and transferred at a specific time. Revenues can be subdivided into the following geographic areas:

ographic areas:
2021 Revenue from contracts with external customers Time point of sales income recognition Revenues recognized at a specific time Revenues gradually recognized with time	$	Taiwan 681,900 677,384 4,516 681,900	$	United States 1,252,802 1,252,802 - 1,252,802	Total $ 1,934,702 $ 1,930,186 4,516 $ 1,934,702
	$		$
	$		$

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2020 Revenue from contracts with external customers $ Time point of sales income recognition Revenues recognized at a specific time $ Revenues gradually recognized with time $	$	Taiwan 745,592 735,636 9,956 745,592	$	United States 797,997 797,997 - 797,997
			$
	$		$

1. Contract assets and contract liabilities

(1) The contract assets and contract liabilities of customer contract revenue recognized by the Group are shown as follows:

Contract assets -Labor services Contract liabilities: -Drug sale contracts -Labor services Total	December 31, 2021 December 31, 2020 January 1, 2020 $- $ 21 $ 452	December 31, 2021 December 31, 2020 January 1, 2020 $- $ 21 $ 452	December 31, 2021 December 31, 2020 January 1, 2020 $- $ 21 $ 452
	$	70,299 $ 3,689	1,263 $ 59,377 2,394 2,263
	$	73,988 $	3,657 $ 61,640

• (2) The initial contract liabilities arising from sales and labor contracts recognized as revenues in 2021 and 2020 total NT$972 and NT$56,136 respectively.

(16) Interest income

(16)	Interest income
(17)	Interest from bank deposits Other interest incomes Other revenue	$	2021 175 $ 6	2020 354 70
		$	181 $	424

Other revenue
Rent revenue Other Revenue- other	$	2021 12,800 5,700	$	2020 1,296 9,538
	$	18,500	$	10,834

(18) Other profits and losses

Other profits and losses
Gain in disposal of property, plant and equipment Net foreign exchange loss Net profit from financial assets and liabilities at fair value through profit and loss Other losses	$ (	2021 - 9,592) 3,270 -	$ ( (	2020 346,826 11,819) 4,296 2,323) 336,980
	($	6,322)	$

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(19) Financial costs

Financial costs
Bank loan Lease liabilities	$	2021 3,273 48 3,321	$	2020 4,704 53 4,757
	$		$

(20) Employee benefit expense, depreciation and amortization

1. Employee benefit expense, depreciation and amortization:

Functionality Characteristics		2021
	Allocated as operating cost	Employee expenses	Total
Employee benefits expenses
Salaries and wages	$ 139,452	$ 202,256	$ 341,708
Labor insurance and national health insurance	12,155	13,363	25,518
Pension expenses	4,188	6,920	11,108
Other employee expenses	9,325	8,862	18,187
Depreciation	97,188	33,226	130,414
Amortization	-	1,579	1,579
Functionality Characteristics		2020
	Allocated as operating cost	Employee expenses	Total
Employee benefits expenses
Salaries and wages	$ 124,930	$ 191,556	$ 316,486
Labor insurance and national health insurance	9,748	12,242	21,990
Pension expenses	3,565	6,447	10,012
Other employee expenses	8,177	13,068	21,245
Depreciation	96,564	32,981	129,545
Amortization	-	1,609	1,609

1. Remunerations for employees and directors:

2. (1) According to the articles of incorporation of the Company, a portion of distributable profit of the current year, after covering accumulated losses, shall be distributed as employees’ compensation and directors’ remuneration. The percentage shall be 1% to 15% for employees’ compensation and shall not be higher than 3% for directors’ remuneration.

3. (2) A. For the 2021, employees’ compensation was accrued at NT$45,777 while directors’ remuneration was accrued at NT$6,613. The aforementioned amounts were recognized in salary expenses.

   • B. For the 2020, employees’ compensation was accrued at NT$39,296 while directors’ remuneration was accrued at NT$7,481. The aforementioned amounts were recognized in salary expenses.

   • C. The employees’ compensation and directors’ remuneration were estimated and accrued based on 8.42% and 1.22% of profit of current year distributable for the 2021, respectively.

   • D. The employees’ compensation and directors’ remuneration resolved by the Board of Directors for 2020 were NT$39,296 and NT$7,481, respectively, consistent with the amount recognized in the 2020 financial report.

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     - E. Information about employees’ compensation and directors’ remuneration of the Company as resolved by the Board of Directors and shareholders will be posted in the “Market Observation Post System”.

• (21) Income tax

• Income tax expense

  • (1) Components of income tax expense:

Income tax expense (1) Components of income tax expense:	Income tax expense (1) Components of income tax expense:
2021 Current income tax: Current income tax $ 98,794 $ Additional levy on undistributed earnings 1,980 Underestimate (overestimated) income tax of prior years 1,061 ( Total Current income tax 101,835 Deferred income tax: Origin and reversal of temporary differences ( 5,272) Income tax expense $ 96,563 $ (2) Income tax amounts relating to other comprehensive profit and loss: 2021 Defined benefit obligation revaluation amount and volume($ 350) $ Reconciliation between income tax expense and accounting profit: 2021 Income tax derived by applying the statutory tax rate to pre-tax net profit $ 104,373 $ Tax-free income by Income Tax Law ( 10,675) ( Impact on income tax from items excluded according to the tax law 12 Realizable changes from deferred income tax assets ( 1,817) Additional levy on undistributed earnings 1,980 Underestimate (overestimated) income tax of prior years 1,061 ( Foreign dividend withholding tax rate difference 1,629 The land value increment tax payable for land sold - Income tax expense $ 96,563 $		2021 98,794 $ 1,980 1,061 (	2020 121,952 112 8,832) 113,232
		101,835
		5,272)	5,002
		96,563 $	118,234
			2020 49
		accounting profit: 2021 104,373 $ 10,675) ( 12 1,817) 1,980 1,061 ( 1,629 -	2020 133,094 9,504) 66 1,546 112 8,832) 686 1,066 118,234
	$	96,563 $

• (2) Income tax amounts relating to other comprehensive profit and loss:

2. Reconciliation between income tax expense and accounting profit:

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1. Deferred income tax assets or liabilities arising from temporary differences:

January 1 Temporary differences - Deferred income tax assets: Falling price of inventory $ 13,826 Excess losses from bad debts - Unrealized exchange loss 424 Impairment loss of fixed assets 1,019 Bonus payable for paid leave not taken 1,489 Unrealized profit from sales of inventories in transit - Subtotal 16,758 Deferred income tax liabilities Profit and loss recognized by using equity method ( 2,678) Determined benefit obligation ( 4,657) Reserve for land revaluation increment tax (“LRIT”) ( 240,164) Subtotal ( 247,499) Total ($ 230,741) January 1 Temporary differences - Deferred income tax assets: Falling price of inventory $ 14,996 Unrealized exchange loss 264 Impairment loss of fixed assets 1,658 Bonus payable for paid leave not taken 1,270 Profit and loss recognized by using equity method 608 Subtotal 18,796 Deferred income tax liabilities Profit and loss recognized by using equity method - Determined benefit obligation ( 4,420) Reserve for land revaluation increment tax (“LRIT”) ( 240,164) Subtotal ( 244,584) Total ($ 225,788)	January 1 Temporary differences - Deferred income tax assets: Falling price of inventory $ 13,826 Excess losses from bad debts - Unrealized exchange loss 424 Impairment loss of fixed assets 1,019 Bonus payable for paid leave not taken 1,489 Unrealized profit from sales of inventories in transit - Subtotal 16,758 Deferred income tax liabilities Profit and loss recognized by using equity method ( 2,678) Determined benefit obligation ( 4,657) Reserve for land revaluation increment tax (“LRIT”) ( 240,164) Subtotal ( 247,499) Total ($ 230,741) January 1 Temporary differences - Deferred income tax assets: Falling price of inventory $ 14,996 Unrealized exchange loss 264 Impairment loss of fixed assets 1,658 Bonus payable for paid leave not taken 1,270 Profit and loss recognized by using equity method 608 Subtotal 18,796 Deferred income tax liabilities Profit and loss recognized by using equity method - Determined benefit obligation ( 4,420) Reserve for land revaluation increment tax (“LRIT”) ( 240,164) Subtotal ( 244,584) Total ($ 225,788)	Recognized in the profit or loss $ 2,388 2,868 ( 179) ( 776) 41 3,380 7,722 ( 2,661) 211 - ( 2,450) $ 5,272 Recognized in the profit or loss ($ 1,170) 160 ( 639) 219 ( 608) ( 2,038) ( 2,678) ( 286) - ( 2,964) ($ 5,002)	Recognized	Recognized	2021 Recognized in other comprehensive net loss $ - - - - - - - - ( 350) - ( 350) ($ 350) 2020 Recognized in other comprehensive net loss $ - - - - - - - 49 - 49 $ 49	2021 Recognized in other comprehensive net loss $ - - - - - - - - ( 350) - ( 350) ($ 350) 2020 Recognized in other comprehensive net loss $ - - - - - - - 49 - 49 $ 49	2021 Recognized in other comprehensive net loss $ - - - - - - - - ( 350) - ( 350) ($ 350) 2020 Recognized in other comprehensive net loss $ - - - - - - - 49 - 49 $ 49
			in	the profit
	16,758
	( 2,678) ( 4,657) ( 240,164)	(						( ( (
	( 247,499)	(						(
	($ 230,741) January 1 $ 14,996 264 1,658 1,270 608		$
			in	the profit
				or loss 1,170) 160 639) 219 608) 2,038) 2,678) 286) - 2,964) 5,002)		$	net loss - - - - - - - 49 - 49 49
	18,796	(
		( (
	( 244,584)	(
	($ 225,788)	($				$

1. The Company's filings of profit-seeking enterprise business income tax returns had been certified by the tax authority up till 2019.

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(22) Earnings per share

(23)

2021 Weighted average outstanding shares (thousand shares). Earnings per share After-tax amount (NT$) Base earnings per share Net income attributable to the parent company $ 400,778 77,560 $ 5.17 Diluted earnings per share Net income attributable to the parent company $ 400,778 77,560 Effect of dilutive potential ordinary shares: Employees’ compensation - 758 Net income attributable to the parent company Potential effect on ordinary shares $ 400,778 78,318 $ 5.12 2020 Weighted average outstanding shares (thousand shares). Earnings per share After-tax amount (NT$) Base earnings per share Net income attributable to the parent company $ 531,873 77,560 $ 6.86 Diluted earnings per share Net income attributable to the parent company $ 531,873 77,560 Effect of dilutive potential ordinary shares: Employees’ compensation - 771 Net income attributable to the parent company Potential effect on ordinary shares $ 531,873 78,331 $ 6.79 Supplemental cash flow information 1. Investment activities with partial cash payments: 2021 2020 Purchase of property, plant, and equipment $ 454,638 $ 199,018 Add: Opening balance of payable on equipment 13,183 5,777 Prepayments for equipment at the end of the period 30,086 - Less: Ending balance of payable on equipment ( 94,544) ( 13,183) Cash Paid for the Period $ 403,363 $ 191,612 2. Investment activities with partial cash collection: 2021 2020 Disposal of property, plant, and equipment $ - $ 1,064,153 Less: Relevant expenses - ( 4,247) Cash received during the year $- $ 1,059,906

(24) Changes in liabilities arising from financing activities

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2021

		2021	2021	2021
January 1 Addition Repayment Other non-cash changes December 31 January 1 Borrowing Repayment Other non-cash changes December 31	Shot-term borrowings $ - 1,310,000 ( 1,160,000) -	Short-term bills payable Long-term borrowings Lease liabilities $ - $ - $ 3,071 50,014 1,200,000 1,913 ( 50,014) ( 600,000) ( 2,712) - - 66 $- $ 600,000 $ 2,338 2020 Short-term bills payable Long-term borrowings Lease liabilities $ 219,740 $ 600,000 $ 5,366 190,306 600,000 - ( 410,046) ( 1,200,000) ( 2,918) - - 623 $- $- $ 3,071			Total liabilities arising from financing activities $ 3,071 2,561,927 ( 1,812,726) 66 $ 752,338 Total liabilities arising from financing activities $ 895,106 1,130,306 ( 2,022,964) 623 $ 3,071
	$ 150,000		$- $	600,000 $
	Shot-term borrowings $ 70,000 340,000 ( 410,000) - $-
					(
						$
						$

7. Related party transactions

(1) Name and relationship of related parties

Name	Relationship with the Group
China Chemical & Pharmaceutical Co., Ltd. (CCPC)	The Group’s main affiliates
Chunghwa Yuming Healthcare Co., Ltd. (CYH)	The Group’s main affiliates
Tairung Development Co., Ltd.	The Group’s main affiliates
Sino-Japan Chemical Co., Ltd.	Other related parties

(2) Major transactions with related parties

1. Operating revenues

Product sales: Affiliate business	$	2021 66,516 $	2020 95,737

(1) The transaction price of the Group’s sales to related parties is based on the price agreed by both parties.

(2) The Group’s payment period is 30–120 days (monthly) for non-stakeholders and 120 days (monthly) for stakeholders after shipment.

~43~

• (3) The Group signed a raw material production and sales contract with China Chemical & Pharmaceutical Co., Ltd. in 2016 and renewed the contract in 2019. The Group sold raw materials to the said party at the net cost +30% profit for processing into goods; the Group is entitled to a differential profit ratio of 50% profit from actual sales (China Chemical & Pharmaceutical Co., Ltd. gross profit and the Group’s sales gross profit).

2. Account receivable from related parties

2. Account receivable from related parties	es
Accounts receivable: CCPC $ Less: Allowance for losses ( $ 3. Other accounts payable to related parties Other payable: Affiliate business $	$ (	December 31, 2021 23,523 46) 23,477	$ (	December 31, 2020 41,998 46) 41,952 December 31, 2020 20
	$		$
		December 31, 2021 145	$

1. The Group’s business supplies purchased in 2021 and 2020 totaled NT$2,770 and NT$2,128, respectively, and are listed as operating cost and miscellaneous fees.

2. On November 8, 2021, the Board of Directors approved that the Group may enter into the Letter of Intent for Land Transaction with Sino-Japan Chemical Co., Ltd. As of March 29, 2022, the parties were still negotiating with each other; the Land Transaction Contract was yet to be officially signed by the Group.

(3) Remuneration to key management

Salaries and other short-term employee benefits Retirement benefits	$	2021 39,524 532	$	2020 40,862 538
	$	40,056	$	41,400

8. Pledged assets

The assets of the Group are offered as collateral as follows:

Book Value

Asset Item Deposits paid (Recognized as Other non-current assets)	$	December 31, 2021 4,000	$	December 31, 2020 Purpose of guarantee 4,000 Tariff guarantee bond

1. Significant contingent liabilities and unrecognized contractual commitments

(1) Contingencies

None.

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(2) Commitments

Capital expenditures that have been signed but not yet incurred

December 31, 2021 December 31, 2020 property , plant, and equipment $ 147,601 $ 445,400

10. Significant disaster loss

None.

11. Major post-balance sheet events

1. Please refer to Note 6 (14) 4 for a description on distribution of surplus for 2021.

2. On March 8, 2022, the Board of Directors approved that the Group can issue common stock shares or domestic convertible corporate bonds through private placement (including secured or unsecured convertible corporate bonds). It is brought forth during the shareholders’ meeting for authorizing the Board of Directors to select appropriate timing and fund-raising tools reflective of the market situation and the needs of the Company for issuance of either one or the combination of the two separately or concurrently.

12. Others

(1) Capital management

The Group’s capital risk management objectives are to ensure that the Group is capable of continuing operations, to maintain the most appropriate capital structure in order to reduce cost of capital and to maximize returns for shareholders. The Group may make adjustments to dividends paid to shareholders, refund capital to shareholders, issue new shares or sell assets to reduce the level of debts in order to maintain or adjust the Group’s capital structure. The Group uses the debt-to-equity ratio to monitor its capital. The ratio is calculated by dividing net debts by total capital. Net debts are calculated as total debts (including “current and non-current borrowings” presented in the consolidated balance sheet) less cash and cash equivalents. Total capital is calculated as “equity” presented in the consolidated balance sheet plus net debts.

The Group maintained the same strategy in 2021 as in 2020. It is committed to keeping the debt-to-capital ratio between 20% and 45%.

~45~

(2) Financial instruments

1.

Types of financial instrument December 31, 2021 December 31, 2020 Financial assets Financial assets at fair value through profit and loss Financial assets mandatorily measured at fair value through profit or loss $ 26,726 $ 32,456 Financial assets based on cost after amortization Cash and cash equivalents 195,250 148,625 Notes receivable 480 344 Accounts receivable (including related parties) 379,400 357,562 Other receivable 16,127 9,653 Deposits paid (Recognized as Other non-current assets) 4,585 7,251 $ 622,568 $ 555,891 Financial liabilities Financial liability measured at the amortized cost Shot-term borrowings $ 150,000 $ - Payable notes 1,215 1,215 Accounts payable 77,550 96,495 Other payable 297,541 187,686 Long-term borrowings 600,000 - Deposits received (Recognized as other current liabilities-others) 266 266 $ 1,126,572 $ 285,662 Lease liabilities (including current and non-current) $ 2,338 $ 3,071

2. Risk management policies

(1) The Group’s activities expose it to a variety of financial risks, including market risk (exchange rate, interest rate and price), credit risk and liquidity risk. The Group’s overall risk management policy focuses on unpredictable events in the financial market, and the Group seeks to mitigate potential adverse effect on the financial position and performance.

• (2) The Group’s Finance Department identifies and assesses financial risks in close collaboration with the Group’s other operating units.

• The nature and extent of significant financial risks

• (1) Market risk

Exchange rate risk

• A. The Group is a multinational operation and therefore is subject to exchange rate risk arising from transactions between the different currencies of the Company and its subsidiaries, mainly in US dollars. The related exchange risk from future operating activities have been recognized in assets and liabilities.

• B. The Finance Department of the Group conducts hedging for the overall

~46~

exchange rate risk. In order to manage the exchange rate risk from future commercial transactions and recognized assets and liabilities, companies within the Group take on the natural hedging approach for general imports and exports to reduce the foreign exchange risk.

• C. The Group’s operations involve certain non-functional currencies (the Company’s functional currency is the New Taiwan dollar (NTD), and subsidiary's functional currency is the USD), so it is subject to the impact of exchange rate fluctuation. The details of assets and liabilities denominated in foreign currencies whose values would be materially affected by exchange rate fluctuations are as follows:

fluctuations are as follows:
		December 31, 2021
	Foreign currency		Book value
	(thousand
	dollars)	Exchange rate	(NTD)
(Foreign currency: Functional
currency)
Financial assets
Monetary items
USD: NTD	$ 15,395	27.68 $ 426,134
Financial liabilities
Monetary items
USD: NTD	$ 1,487	27.68 $ 41,160
		December 31, 2020
	Foreign currency		Book value
	(thousand	Exchange rate	(NTD)
	dollars)
(Foreign currency: Functional
currency)
Financial assets
Monetary items
USD: NTD	$ 13,185	28.48 $ 375,509
Financial liabilities
Monetary items
USD: NTD	$ 2,700	28.48 $ 76,896

• D. Total exchange gain, including realized and unrealized gains from significant foreign exchange variations on monetary items held by the Group amounted to a gain of (NT$9,592) and a loss of (NT$11,819) for the years ended December 31, 2021 and 2010, respectively.

~47~

• E. The analysis of foreign currency risk due to significant exchange rate fluctuation is as follows:

is as follows:
			2021
		Sensitivity analysis
	Magnitude	Profit and	loss	Other comprehensive
	changes	affected		profit and loss affected
(Foreign currency: Functional
currency)
Financial assets
Monetary items
USD: NTD	1%	$ 4,261		$ -
Financial liabilities
Monetary items
USD: NTD	1%	($ 412)		$ -
			2020
		Sensitivity analysis
	Magnitude	Profit and loss		Other comprehensive
	changes	affected		profit and loss affected
(Foreign currency: Functional
currency)
Financial assets
Monetary items
USD: NTD	1%	$ 3,755 $ -
Financial liabilities
Monetary items
USD: NTD	1%	($ 769) $ -
Price risk

• A. The equity instruments of the Group that are exposed to price risks are those financial assets held at fair value through profit and loss. To manage the price risk of equity instruments, the Group diversifies its investment portfolio in a manner that is based on the limits set by the Group.

• B. The Group invests primarily in equity instruments issued by domestic companies. The price of such equity instrument is subject to the uncertainty of the future value of investment target. In case the price of the said equity instrument rises or drops by 10% while the other factors remain unchanged, the after-tax net profit for 2021 and 2020 due to the profit or loss of the equity instrument measured from fair value through profit and loss will increase or decrease by NT$2,673 and NT$3,246 respectively.

Cash flow and fair value interest rate risk

• A. The Group’s interest rate risk mainly comes from short-term borrowings issued at floating rates and long-term borrowing, which exposes the Group to cash flow interest rate risk. As a policy of the Group, a fixed interest rate is maintained for at least 40% of borrowings. For 2021 and 2020, the Group’s borrowings issued at floating rates were mainly denominated in New Taiwan dollars.

• B. If the interest rates of borrowing NTD and USD increases or decreases by 1%, while all other factors remain constant, the net profit after tax for 2021 and 2020 is an increase of $5,600 and $0, respectively, mainly due to the interest expense changes caused by the floating interest rate.

• (2) Credit risk

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• A. Credit risk refers to the risk of financial loss of the Group arising from default by the clients or counterparties of financial instruments under contract obligations, and the defaults are accounts receivable.

• B. The management of credit risk is established with a Group perspective. According to the Company’s credit policy, each local entity in the Group is responsible for managing and analyzing the credit risk for each of their new clients before standard payment and delivery terms and conditions are offered. Internal risk control assesses the credit quality of the customers, taking into account their financial position, past experience and other factors. Individual risk limits are set based on internal or external ratings in accordance with limits set by the Office of the General Manager. The utilization of credit limits is regularly monitored.

• C. The Group uses IFRS 9 to provide an assumption that if a contract payment is overdue for more than 90 days in accordance with the agreed payment terms, it is considered a breach of contract.

• D. The Group uses IFRS 9 to provide the following assumption as a basis for determining whether there is a significant increase in the credit risk of financial instruments after the original recognition: If the contract payment is overdue for more than 30 days in accordance with the agreed payment terms, the credit risk of the financial asset is significantly increased since the original recognition.

• E. The Group categorizes the accounts receivable from customers based on their nature. The provision matrix and the loss ratio method are adopted as the basis for estimating the expected credit loss.

• F. The Group may write off the amount of financial assets that cannot be reasonably expected to be recovered after recourse. However, the Group will still continue the recourse to protect the rights of the claims. For the year ended December 31, 2021 and 2010, the Group has no creditor’s rights that have been written off but are involved in recourse.

• G. The Group has included the global economic indicators and signals and estimated the loss allowance for notes receivable and accounts (including the interested parties) based on the loss rates built according to historic and current data. The provision matrix and loss rate as of December 31, 2021 and 2020 are show as follows:

show as follows:
December 31, 2021 Not overdue Overdue within 30 days Overdue 31 to 60 days Overdue 61 to 90 days Overdue 91 December 31, 2020 Not overdue Overdue within 30 days Overdue 31 to 60 days Overdue 61 to 90 days Overdue 91	Expected rate of loss 0.02%~0.17% $ 0.21%~2.08% 0.21%~2.12% 0.80%~8% 10%~100% $ Expected rate of loss 0.02%~0.20% $ 0.25%~2.46% 0.25%~2.50% 0.68%~6.67% 10%~100% $		Total book value 116,465 - - - 18,345 134,810 Total book value 105,899 105 - - - 106,004		Allowance for losses $ 294 - - - 18,345 $ 18,639 Allowance for losses $ 285 9 - - - $ 294
	0.02%~0.20% 0.25%~2.46% 0.25%~2.50% 0.68%~6.67% 10%~100%
		$

The customers of Pharmaports, LLC, one of the Company’s subsidiaries, prove very sound in credit standing. The previous experiences show no default record at all. The anticipated loss rate is, therefore, at 0.2%. As of December 31, 2020 and 2020, the total receivable book value and the allowance for loss amounted to

~49~

NT$263,727 and NT$18 and NT$252,214 and NT$18.

• H. The Group adopts a simplified method in which the loss allowance for the accounts receivable is shown below:

accounts receivable is shown below:
January 1 Impairment loss is recognized December 31 January 1 Impairment loss is recognized December 31	2021 Notes receivable and accounts (including interested parties) $ 312 18,345
	$	18,657
	2020 Notes receivable and accounts (including interested parties) $ 312 - $ 312

The amount recognized above is based on other credit enhancements held, so the unrecognized loss allowance as of December 31, 2021 and 2020 are NT$200 and NT$559. Among the reversed loss in 2021 and 2020, $0 is the impairment loss reversed by payables derived from customer contracts.

• (3) Liquidity risk

• A. Cash flow forecasting is performed by the operating entities of the Group and aggregated by the Group’s finance department. It monitors rolling forecasts of liquidity requirements to ensure the Group has sufficient cash to meet operational needs and maintain sufficient unencumbered loan commitments at all times. Such forecasting takes into consideration the Group’s debt financing plans, covenant compliance, and compliance with internal balance sheet ratio targets.

B. The Group’s unutilized borrowings are shown as follows:

Maturing in one year or less Mature beyond one year	December 31, 2021 $ 920,000 -	December 31, 2020 $ - 200,000 $ 200,000
	$ 920,000

• C. The table below analyses the Group’s non-derivative financial liabilities into relevant maturity groupings based on the remaining period at the balance sheet date to the contractual maturity date for non-derivative financial liabilities. The amounts disclosed in the table are the contractual undiscounted cash flows.

Non-derivative financial liabilities: December 31, 2021 Within 1 year Payable notes $ 1,215 $ Accounts payable 77,550 Other payable 297,541 Lease liabilities 1,338 Deposits received (Recognized as other current liabilities-others) 266 Non-derivative financial liabilities: December 31, 2020 Within 1 year	1 to 2 years - $ - - 772 - 1 to 2 years	2 to 5 years - - - 253 - 2 to 5 years

~50~

Payable notes	$ 1,215 $ - $ -
Accounts payable	96,495 - -
Other payable	187,686 - -
Lease liabilities	2,370 700 123
Deposits received
(Recognized as other
current liabilities-others)	266 - -

• (3) Fair value information

• The different levels that the inputs to valuation techniques are used to measure fair value of financial and non-financial instruments have been defined as follows:

  • Level 1: The quotation (unadjusted) of the same assets or liabilities that can be acquired by the company in an active market on the measurement date A market is regarded as active where a market in which transactions for the asset or liability take place with sufficient frequency and volume to provide pricing information on an ongoing basis. The fair value of the Group’s investment in publicly traded or OTC stocks is included.

  • Level 2: It refers to the directly or indirectly observable input value of asset or liability, except for those quotations included in Level 1.

  • Level 3: The unobservable inputs of assets or liabilities.

• Please refer to Note 6 (7) for the fair value of investment property carried at cost.

• Financial instrument not measured at fair value:

  • Include the book value of cash and cash equivalents, notes receivable, accounts receivable (including the interested parties), other receivable, short-term borrowings, long-term borrowings, notes payable, accounts payable, other accounts payable and lease liabilities as reasonable approximation of fair value.

• The related information for financial and non-financial instruments measured at fair value by level on the basis of the nature, characteristics and risks of the assets and liabilities is as follows:

  • (1) The Group classifies them based on the nature of assets and liabilities, and the information is as follows:

information is as follows:
December 31, 2021 Assets Repeatable fair value Financial assets at fair value through profit and loss Equity securities December 31, 2020 Assets Repeatable fair value Financial assets at fair value through profit and loss Equity securities	$	Level 1 -	$	Level 2 - $	Level 3 26,726 $	Total 26,726 Total 32,456
	$	Level 1 -	$	Level 2 - $	Level 3 32,456 $

~51~

• (2) The methods and assumptions adopted by the Group to measure fair value are as follows:

  • A. The fair value of other financial instruments is obtained by valuation or reference to quotation from counterparties.

  • B. When assessing non-standardized and less complex financial instruments, the Group adopts valuation techniques widely used by other market participants. The parameters used in the valuation models for this type of financial instruments are usually observable market information.

  • C. The output of valuation models are estimates, and the valuation techniques may not reflect all factors affecting the financial instruments and non-financial instruments held by the Group. Therefore, the estimates of valuation models will be adjusted according to additional parameters, such as model risk or liquidity risk. Based on the management policies of the Group’s valuation model at fair value and the related control procedures, the management believes that to fairly present the fair value of financial and non-financial instruments in the consolidated balance sheet, adjusting valuation may be appropriate and necessary. Price information and parameters used in valuation are carefully assessed and they are appropriately adjusted according to the current market conditions.

• There were no transfers between Level 1 and 2 in 2021 and 2020.

• The following table shows the changes in Level 3 in 2021 and 2020:

January 1 Income recognized in profit or loss (Note) Payment on shares refunded by capital decrease December 31 Note: Other gains and losses listed.	$ (	2021 Equity instruments 32,456 3,270 9,000) 26,726	$	2020 Equity instruments 28,160 4,296 - 32,456
	$		$

1. There were no transfers in and/or out of Level 3 in 2021 and 2020.

2. With respect to the valuation of fair value classified as Level 3, the Finance Department is responsible for the independent verification of fair value of financial instruments. Based on independent information, the valuation results can be closer to the market conditions. The independence and reliability of information and the consistency with other sources, as well as other necessary adjustments to the fair value, can ensure that the results are reasonable.

In addition, the Finance Department develops valuation policies and procedures for fair value of financial instruments and ensure that they comply with the requirements of the International Financial Reporting Standards.

1. The quantitative and sensitivity analysis of significant and unobservable input of valuation models used for measuring Level 3 fair value is shown as follows:

Fair value as of December 31, 2021 Shares of venture capital $ 26,726 Fair value as of December 31, 2020	Valuation technique Net asset value method Valuation technique	Significant unobservable input value Not applicable Significant unobservable input value	Relationship between	Relationship between
			input value and fair value Not applicable Relationship between
				input value and fair value

~52~

Shares of venture Net asset value capital $ 32,456 method Not applicable Not applicable

1. The Group conducts careful assessment before determining the valuation model and parameters to be used, and the use of different valuation models or parameters may lead to different valuation results.

(4) Other matters

In response to the COVID-19 pandemic and the multiple preventive measures promoted by the government, the Group has split operations and continued to address related matters; it is determined that there are no major impacts on the financial standing and performance of the Group.

13. Notes of disclosure

(1) Information about important transactions

In accordance with the provisions of the Regulations Governing the Preparation of Financial Reports by Securities Issuers. the major transactions related to the Group in 2021 are as follows:

1. Loans to others: None

2. Provision of endorsements and guarantees to others: None

3. Holding of marketable securities at the end of the period (not including subsidiaries, associates and joint ventures): Please refer to Table 1.

4. The cumulative purchase or sale of the same security for an amount exceeding NT$300 million or 20% of paid-in capital: Not applicable.

5. Acquisition of real estate reaching $300 million or 20% of paid-in capital or more: None.

6. Disposition of real estate properties amounting to more than NTD300 million or 20% of paid up capital: Not applicable.

7. Purchases or sales of goods from or to related parties reaching $100 million or 20% of paid-in capital or more: Please refer to Attached table 2.

8. Receivables from related parties reaching $100 million or 20% of paid-in capital or more: Please refer to Table 3.

9. Engaged in derivatives trading: None.

10. Significant inter-company transactions during the reporting periods: Please refer to Table 4.

(2) Information regarding investees

Names, locations and other information of investee companies (not including investees in China): Please refer to Table 5.

• (3) Information regarding investment in the territory of mainland china

• Basic information: None.

• Significant transactions, either directly or indirectly through a third area, with investee companies in China: None.

(4) Information of major shareholders

Information of major shareholders: Please refer to Table 6.

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14. Segment information

(1) General information

Management has determined the reportable operating segments based on reports reviewed by the general manager and used to make strategic decisions. The general manager operates the business from a geographical perspective, with the production and sales of active pharmaceutical ingredients being the main sources of income. Taiwan is mainly responsible for sales and research and development, and the US mainly is involved in sales. The Group provides the operating results of entities in the consolidated statements to the chief operating decision-maker for review and uses the information to evaluate performance of the departments.

(2) Evaluation of department information

The Group presents the chief operating decision-maker with the pre-tax net profit or loss of each region which uses consistent measurement for revenue and expense in the income statements, and the performance of each operating department is evaluated based on the pre-tax net profit or loss.

The Group did not provide the chief operating decision-maker with total assets and liabilities for operational decisions.

(3) Segment profit/loss

Information on the reporting segments provided to the chief operating decision maker is shown as follows:

shown as follows:
2021 Revenue from external clients Revenue from internal transactions Department income Segment profit/loss Segment profit and loss include: Depreciation and amortization 2020 Revenue from external clients Revenue from internal transactions Department income Segment profit/loss Segment profit and loss include: Depreciation and amortization	Taiwan $ 681,900 1,214,722 $ 1,896,622 $ 477,920 $ 130,865 Taiwan $ 745,592 769,552 $ 1,515,144 $ 636,958 $ 129,968	United States $ 1,252,802 - $ 1,252,802 $ 19,693 $ 1,128 United States $ 797,997 - $ 797,997 $ 13,339 $ 1,186	(	Adjustment and	Total $ 1,934,702 -
					$ 1,934,702 $ 497,613
					$
					$	131,993
			(		Total $ 1,543,589 -
				$
			($		$ 1,543,589 $ 650,297
			$
			$		$ 131,154

(4) Reconciliation of segment profit and loss

The reports provided to the chief operating decision-maker for the segments’ operating decision are not different from the segments’ profit and loss statement, so no adjustment is required.

~54~

(5) Information on types of product and labor service

The income from external customers is mainly in the forms of manufacturing and sales of APIs, and the breakdown of income balance is shown as follows:

Sales revenue of biotechnology products Sales revenue of non-biotech products Labor revenue	$	2021 852,641 1,077,545 4,516 1,934,702	$	2020 1,045,679 487,954 9,956
	$		$	1,543,589

(6) Information by areas

Information by region for the Group in 2021 and 20120:

Taiwan U.S. Japan India Ireland Others Total	$	2021 Income 113,905 $ 1,252,802 124,206 148,507 108,450 186,832 1,934,702 $	2021	2021	Non-Current assets 1,880,520 448 - - - -	Non-Current assets 1,880,520 448 - - - -	$	2020 Income 151,562 $ 797,997 147,931 124,543 - 321,556 1,543,589 $	2020	2020	Non-Current assets 1,552,745 1,609 - - - - 1,554,354
				$						$
	$	1,934,702		$		1,880,968	$	1,543,589		$

(7) Information about important customers

Major clients who accounted for more than 10% of the sales in 2021 and 2020:

Client A $ Client B	Income 968,881 -	2021 Department United States $ Taiwan	Income

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Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries

Holding of marketable securities at the end of the period (not including subsidiaries, associates and joint ventures)

January 1 to December 31, 2021

Attached table 1									Unit: NTD thousand
								(Except where otherwise stated)
					At ending
	Type and name of marketable securities	Relationship with the securities				Shareholding
Holding company	(Note 1)	issuer	Account titles in book	Quantity	Book value (Note 2)	percentage		Fair value	Remarks
Chunghwa Chemical Synthesis &	Common shares	None	Financial assets at fair value through	2,100,000	$ 26,726		1.71% $ 26,726		None
Biotech Co., Ltd.	China Development Biomedical Venture		profit and loss
	Capital (limited company)

Note 1: Securities as stated in this table are the stocks, bonds, beneficiary certificates and the securities deriving from the above items within the scope of IFRS 9, “Financial Instruments”. Note 2: Book value is determined based on fair value less accumulated impairment for marketable securities measured at fair value. For those not measured at fair value, the book value is determined based on the acquisition cost or amortized cost less accumulated impairment.

Attached table 1 Page 1

Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries

Purchase from or sale to related parties for an amount exceeding NT$100 million or 20% of paid-in capital

January 1 to December 31, 2021

Attached table 2

Unit: NTD thousand (Except where otherwise stated)

Trading terms different from general trade and Transactions reasons Notes and accounts receivable (payable) Percentage of Percentage of total notes, total purchase The credit accounts receivable Purchase (sale) company Name of counterparty Relation Purchase (sale) Amount (sale) period Unit price The credit period Balance (payable) Remarks Chunghwa Chemical Synthesis & PHARMAPORTS, LLC Subsidiaries Sale $ 1,214,722 64% Collection The agreed amount of the - $ 265,727 66% None Biotech Co., Ltd. period is 60 to two parties 90 days after delivery.

Note: The disclosure is made by the income and corresponding transactions will not be disclosed additionally.

Attached table 2 Page 1

Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries

1. Receivables from related parties reaching $100 million or 20% of paid-in capital or more

January 1 to December 31, 2021

Attached table 3									Unit: NTD thousand
									(Except where otherwise stated)
						Overdue Receivables	from related parties	Receivables amount collected
					Turnover			from related parties
The company booked in the receivables	Name of counterparty	Relation	Receivables from related party		rate	Amount	Disposal Method	subsequently	Provision for loss allowance
Chunghwa Chemical Synthesis & Biotech	PHARMAPORTS, LLC	Subsidiaries	$ 265,727		4.76	$ -	-	$ 265,727	$ -
Co., Ltd.
"	"	"	3,678	(Note)	-	-	-	-	-

Note: As other receivables.

Attached table 3 Page 1

Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries

Significant inter-company transactions during the reporting periods

January 1 to December 31, 2021

Attached table 4

Unit: NTD thousand

(Except where otherwise stated)

Code (Note 1) Trader’s name Counterparty 0 Chunghwa Chemical Synthesis & Biotech Co., Ltd. PHARMAPORTS, LLC 0 Chunghwa Chemical Synthesis & Biotech Co., Ltd. PHARMAPORTS, LLC 0 Chunghwa Chemical Synthesis & Biotech Co., Ltd. PHARMAPORTS, LLC 0 Chunghwa Chemical Synthesis & Biotech Co., Ltd. PHARMAPORTS, LLC	Relationship (Note 2) Item 1 Sales revenue $ 1 Accounts receivable 1 Other revenue 1 Other receivable	Transactions Amount Terms and conditions 1,214,722 Note 4 265,727 Note 4 6,468 Note 4 3,678 Note 4	Percentage of consolidated total	Percentage of consolidated total
				operating revenues or total assets (Note 3) 63% 6% 0% 0%

Note 1: The information about transactions between parent company and subsidiaries shall be numbered and noted in the following manner in the box of numbers:

(1) Fill in “0” for parent company.

(2) Subsidiaries are numbered from number 1.

Note 2: The relationship with the traders is classified into three categories, which should be specified (the transaction conducted between the parent company and its subsidiaries or between two subsidiaries need not be disclosed in duplication). Such as: if the parent company has the transaction with the subsidiaries disclosed, the subsidiaries need not to have it disclosed in duplication. If one of the two subsidiaries has the transaction disclosed, the other subsidiary needs not to have it disclosed in duplication).

• (1) Parent company vs. subsidiaries.

• (2) Subsidiaries vs. parent company.

• (3) Subsidiaries vs. subsidiaries.

Note 3: For computing the ratio of trade amount to total sales revenue or total assets, if it is for asset and liability account, the computation is based on the ratio of ending balance to total consolidated assets; however, if it is for income and expense account, the computation is based on the ratio of interim cumulative amount to total consolidated revenue.

Note 4: Payment collection terms for sales and service provided to related parties are 60 to 90 days after shipment and provision of service, respectively.

Attached table 4 Page 1

Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries

Names, locations and other information of investee companies (not including investees in China)

January 1 to December 31, 2021

Attached table 5

Unit: NTD thousand

(Except where otherwise stated)

Investor Name of investee Location Principal business Chunghwa Chemical Synthesis & Biotech Co. Ltd. PHARMAPORTS, LLC U.S. Trading of API drugs $ Chunghwa Chemical Synthesis & Biotech Co. Ltd. China Chemical & Pharmaceutical Co., Ltd. Taiwan Manufacturing and sales of pharmaceuticals and health care products and import of the related medical equipment.	Sum of initial investment Current period-end The end of last year 4,925 $ 4,925 863,602 463,641	Ending shareholding Quantity Ratio - 98.00% $ 42,053,137 14.11%	Ending shareholding	Book value 9,289 1,032,860	Current period profit / loss of the investee $ 13,579 517,508	Recognized investment Income Remarks $ 13,308 Subsidiaries 50,100 Affiliate business
						$

Attached table 5 Page 1

Chunghwa Chemical Synthesis & Biotech Co., Ltd. and its subsidiaries

Information of major shareholders December 31, 2021

Attached table 6 Shareholding Name of main shareholder Number of shares held Shareholding percentage China Chemical & Pharmaceutical Co., Ltd. 21,509,064 27.73

Attached table 6 Page 1