BOTANIX PHARMACEUTICALS LTD — AGM Information 2021

Sep 19, 2021

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20 September 2021

Dear Shareholder

Annual General Meeting – Notice and Proxy Form

Notice is hereby given that its Annual General Meeting ( Meeting ) of Shareholders of Botanix Pharmaceuticals Limited (ABN 70 009 109 755) ( Company ) will be held at the offices of BDO, 38 Station St, Subiaco WA 6008 on 26 October 2021 at 9.00 am (AWST).

In accordance with the Treasury Laws Amendment (2021 Measures No. 1) Act 2021 (Cth), the Company will not be dispatching physical copies of the Notice of Annual General Meeting ( Notice ) unless a shareholder has requested a hard copy. Instead, a copy of the Notice, which was released to the ASX on - 20 September 2021, can be viewed and downloaded at https://botanixpharma.com/category/asx releases/.

The Board has made the decision that it will hold a physical Meeting with the appropriate social gathering and physical distancing measures in place to comply with the Federal Government’s and State Government’s current restrictions for physical gatherings.

Shareholders are encouraged to submit a proxy vote either online at https://investor.automic.com.au/#/loginsah, or by returning the personalised proxy form (enclosed) in accordance with the instructions set out on the proxy form.

Your proxy voting instruction must be received by 9.00 am (AWST) on 24 October 2021, being not less than 48 hours before the commencement of the Meeting. Any proxy voting instructions received after that time will not be valid for the Meeting.

Circumstances relating to COVID-19 my change rapidly. The Company will update shareholders if changing circumstances will impact planning or the arrangements for the Meeting by way of announcement on ASX and the details will also be made available on our website at www.botanixpharma.com.

The Notice is important and should be read in its entirety. If you are in doubt as to the course of action you should follow, you should consult your financial adviser, lawyer, accountant or other professional adviser. If you have any difficulties obtaining a copy of the Notice of Meeting please contact the Company’s share registry, Automic Group Pty Ltd on, 1300 288 664 (within Australia) or +61 2 9698 5414 (overseas).

Yours sincerely

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Simon Robertson Company Secretary

Botanix Pharmaceuticals Limited ACN 009 109 755 Level 1, 50 Angove Street, North Perth, WA 6006