Zealand Pharma

Major Shareholding Notification • Mar 18, 2015

Copenhagen, 2015-03-18 14:48 CET (GLOBE NEWSWIRE) -- Copenhagen, 18 March 2015–
Zealand Pharma (Nasdaq Copenhagen: ZEAL) (“Zealand”) has received a major
shareholder announcement from Innovation Capital S.A.S, 57 Franklin D.
Roosevelt, 75008 Paris (French registration no. 424 386 795) (”Innovation
Capital”).

Pursuant to Section 29 of the Danish Securities Act, cf. executive order no.
668 of 25 June 2012 on major shareholders and the Danish Companies Act section
55, cf. section 56, it has been announced that Innovation Capital no longer
manages nor control the voting rights of CDC Entreprises Capital Investissement
(French registration no. 351 910 625).

Further, on 17 March 2015 it has been announced that funds managed by
Innovation Capital have sold shares in Zealand Pharma A/S.

Accordingly, Innovation Capital manages and may exercise voting rights on
1,137,669 shares, corresponding to less than 5% of the company’s share capital
and voting rights.

Innovation Capital has been a shareholder in Zealand since 2006.

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For further information, please contact:
Hanne Leth Hillman, Vice President and Head of IR & Corporate Communications
Tel: +45 5060 3689, email: hlh@zealandpharma.com

About Zealand Pharma

Zealand Pharma A/S (“Zealand”) (Nasdaq Copenhagen: ZEAL) is a biotechnology
company based in Copenhagen, Denmark. Zealand has leading expertise in the
discovery, design and development of novel peptide medicines and possesses
in-house competences in clinical trial design and management with a therapeutic
focus on metabolic diseases and acute care indications. The company is
advancing a proprietary pipeline of novel medicines alongside a partnered
product and development portfolio.

Zealand’s first invented medicine, lixisenatide, a once-daily prandial GLP-1
agonist for the treatment of Type 2 diabetes, is marketed globally (ex-US) as
Lyxumia® and in Phase III development as a single-injection combination with
Lantus® (LixiLan), both under a global license agreement with Sanofi. US
regulatory submission of Lyxumia® is planned for Q3 2015 and US/EU regulatory
submissions for LixiLan in Q4 2015.

Zealand proprietary pipeline includes danegaptide (prevention of Ischemic
Reperfusion Injury) and the stable glucagon product, ZP4207 (treatment of
severe hypoglycemia) as well as several preclinical peptide therapeutics.
Partnering represents an important component of strategy to leverage in-house
expertise, share development risk in large clinical trials, provide funding and
commercialize the company’s products. Zealand currently has global license
agreements and partnerships with Sanofi, Helsinn Healthcare, Boehringer
Ingelheim and Eli Lilly.

For further information: www.zealandpharma.com Follow us on Twitter
@ZealandPharma