VERTEX PHARMACEUTICALS INC / MA — Director's Dealing 2017

Jul 21, 2017

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: VERTEX PHARMACEUTICALS INC / MA (VRTX)
CIK: 0000875320
Period of Report: 2017-07-19

Reporting Person: SMITH IAN F (EVP, CFO & COO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2017-07-19	Common Stock	M	25500	$96.87	Acquired	151738	Direct
2017-07-19	Common Stock	M	10775	$91.05	Acquired	162513	Direct
2017-07-19	Common Stock	M	55250	$77.31	Acquired	217763	Direct
2017-07-19	Common Stock	M	31875	$83.36	Acquired	249638	Direct
2017-07-19	Common Stock	S	123400	$161.00	Disposed	126238	Direct
2017-07-21	Common Stock	S	400	$157.56	Disposed	125838	Direct
2017-07-21	Common Stock	S	1829	$158.62	Disposed	124009	Direct
2017-07-21	Common Stock	S	815	$159.61	Disposed	123194	Direct
2017-07-21	Common Stock	S	2000	$161.01	Disposed	121194	Direct
2017-07-21	Common Stock	S	5106	$161.71	Disposed	116088	Direct
2017-07-21	Common Stock	S	200	$162.40	Disposed	115888	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2017-07-19	Stock Option (Right to Buy)	$96.87	M	25500	Disposed	2024-07-14	Common Stock (25500)	Direct
2017-07-19	Stock Option (Right to Buy)	$91.05	M	10775	Disposed	2026-02-01	Common Stock (10775)	Direct
2017-07-19	Stock Option (Right to Buy)	$77.31	M	55250	Disposed	2024-02-04	Common Stock (55250)	Direct
2017-07-19	Stock Option (Right to Buy)	$83.36	M	31875	Disposed	2023-07-29	Common Stock (31875)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	5306	Indirect

Footnotes

F1: Transaction made pursuant to Mr. Smith's company-approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $157.56 (range $156.99 to $157.90).

F3: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $158.62 (range $158.11 to $159.09).

F5: Open market sales reported on this line occurred at a weighted average price of $159.61 (range $159.16 to $159.90).

F6: Open market sales reported on this line occurred at a weighted average price of $161.01 (range $160.28 to $161.24).

F7: Open market sales reported on this line occurred at a weighted average price of $161.71 (range $161.28 to $162.20).

F8: Open market sales reported on this line occurred at a weighted average price of $162.40 (range $162.39 to $162.40).

F9: The option vests in 16 quarterly installments from 7/15/2014.

F10: The option vests in 16 quarterly installments from 02/02/2016.

F11: The option vests in 16 quarterly installments from 02/05/2014.

F12: The option vests in 16 quarterly installments from 07/30/2013.