VERTEX PHARMACEUTICALS INC / MA — Director's Dealing 2012

Mar 2, 2012

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: VERTEX PHARMACEUTICALS INC / MA (VRTX)
CIK: 0000875320
Period of Report: 2012-02-29

Reporting Person: Silva Paul M (SVP & Corp Controller)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2012-02-29	Common Stock	S	6875	$39.36	Disposed	6125	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	1380	Indirect

Footnotes

F1: Open market sales reported on this line occurred at a weighted average price of $39.36 (range $39.34 to $39.39).

F2: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.