VERTEX PHARMACEUTICALS INC / MA — Director's Dealing 2012

Oct 15, 2012

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: VERTEX PHARMACEUTICALS INC / MA (VRTX)
CIK: 0000875320
Period of Report: 2012-10-11

Reporting Person: SMITH IAN F (EVP & CFO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2012-10-11	Common Stock	M	7680	$28.84	Acquired	31848	Direct
2012-10-11	Common Stock	M	6363	$18.93	Acquired	38211	Direct
2012-10-11	Common Stock	S	14043	$60.00	Disposed	24168	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2012-10-11	Employee Stock Option (right to buy)	$28.84	M	7680	Disposed	2017-07-11	Common Stock (7680)	Direct
2012-10-11	Employee Stock Option (right to buy)	$18.93	M	6363	Disposed	2018-02-06	Common Stock (6363)	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	5185	Indirect

Footnotes

F1: Transaction made pursuant to Mr. Smith's company approved trading plan under Rule 10b5-1.

F2: Fully vested.