VERTEX PHARMACEUTICALS INC / MA — Director's Dealing 2011

May 18, 2011

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: VERTEX PHARMACEUTICALS INC / MA (VRTX)
CIK: 0000875320
Period of Report: 2011-05-17

Reporting Person: Kearney Terrence C (Director)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2011-05-17	Stock Option	$56.99	A	30000	Acquired	2021-05-16	Common Stock (30000)	Direct

Footnotes

F1: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 05/17/2011.