VERTEX PHARMACEUTICALS INC / MA — Director's Dealing 2011

Mar 24, 2011

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: VERTEX PHARMACEUTICALS INC / MA (VRTX)
CIK: 0000875320
Period of Report: 2011-03-23

Reporting Person: ULLIAN ELAINE (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2011-03-23	Common Stock	M	7500	$44.47	Acquired	12500	Direct
2011-03-23	Common Stock	S	7235	$46.08	Disposed	5265	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2011-03-23	Stock Option	$44.47	M	7500	Disposed	2011-05-31	Common Stock (7500)	Direct

Footnotes

F1: Open market sales reported on this line occurred at a weighted average price of $46.08 (range $46.07 to $46.11).

F2: Ms. Ullian undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.