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USCOM LIMITED — Investor Presentation 2015
Jul 19, 2015
65979_rns_2015-07-19_6c0effc9-3ca5-4881-8820-d7565ac581b3.pdf
Investor Presentation
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Investor Presentation July 2015
Global Momentum
Rob Phillips
PhD(med), MPhil(med), FASE, DMU(cardiol) Associate Professor, Critical Care Research Group, School of Medicine, The University of Queensland CEO
The Measure of Life
Disclaimer
This presentation is intended to provide a general outline only and is not intended to be a definitive statement on the subject matter. The information in this presentation, whether written or verbal, has been prepared without taking into account the commercial, financial or other needs of any individual or organisation.
While Uscom (the "Company”) has taken due care in compiling the information, neither the Company nor its officers or advisors or any other person warrants the accuracy, reliability, completeness or timeliness of the information or guarantees the commercial or investment performance of the Company. Certain information may relate to protected intellectual property rights owned by Uscom. By viewing this presentation the viewer accepts the terms of the accompanying Company NDA. The information does not constitute advice of any kind and should not be relied on as such. Investors must make their own independent assessment of the Company and undertake such additional enquiries as they deem necessary or appropriate for their own investment purposes. Any and all use of the information is at your own risk.
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See video at news.bbc.co.uk/2/hi/uk_news/england/nottinghamshire/8525901.stm or on Uscom YouTube channel
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Uscom Vision
Company of the Year, 2014 Johnson & Johnson Innovation Industry Excellence Awards
“A milestone driven Australian bio device company with real products, real revenue and real growth which is approaching profitability”
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Current Business
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Premium noninvasive cardiovascular monitoring devices
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Addressing the growing threat of superbugs
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Validated, clinically accepted, cost and life saving devices
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Patent protected with regulatory approvals and full ownership of IP
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Rapidly growing revenues in major markets and new untouched markets
2015 Financials
-
Corporate Board & Management 2015 Financials
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ASX listed (UCM) Rob Phillips, Chairman & CEO Sales +125% H1 2015 YOY[] Headquartered in Sydney Sheena Jack, Director Revenue +147% H1 2015 (HCF, Moneytime Health) YOY[] Market cap of $17m
-
80m shares on issue Christian Bernecker, Director Gross Margins ~ 78% (Stream)
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Rob Phillips, Founder and Cash at bank $0.60m[** ] CEO, holds 21% of Nick Schicht, General Manager Company holds no debt company
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- Uscom half year reports
** Quarter ended 31 March
Current Products
USCOM 1A
Cardiac Output Monitor
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USCOM 1A
BP+
Blood Pressure Monitor
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BP+
-
World leading technology offering huge potential savings to global healthcare systems
-
Next generation blood pressure monitoring providing central and brachial BP measurement
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Sold into hospitals, emergency departments, ICUs, anesthesia and paediatrics
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Growing global distribution and revenue
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Sold to hypertension & research clinics and ICUs
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Pulsecor acquired and integrated by Uscom in 2012 now preparing for mass market
Non-invasive, real time, beat-to-beat
haemodynamics
A stand-alone, non-invasive, accurate and compact system
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Strong Competitive Advantage
USCOM 1A BP+
Cardiac Output Monitor
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USCOM 1A
Blood Pressure Monitor
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BP+
-
Measures flow at heart
-
Measures pressure at heart
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Noninvasive – replaces catheters
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Noninvasive – replaces catheters
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Addresses superbug threat
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Superior to “arm” pressure
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Accurate, quick and simple to use
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Reduces drugs used
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Patent protected
-
Patent protected
Disruptive devices which are superior to current products
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Targeting Strong Revenue Growth…
USCOM 1A
Cardiac Output Monitor
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USCOM 1A
BP+
Blood Pressure Monitor
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BP+
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US$1.3bn global market with CAGR of 7.6%[** ]
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US$1.7bn global market with CAGR of 11.5%[** ]
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Increasing unit sales globally
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US$7m China distribution agreement signed[****]
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Australian reimbursement expected Q1 2016
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US reimbursement obtained for Q1 2016
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80% Gross Margins & $12k profit / unit[***]
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70% Gross Margins & US$1.1k profit / unit[***]
Global revenue opportunities only just beginning to be tapped, with two consecutive years of 60%[+] revenue growth[ *]
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2014/15 FY figures unaudited
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** Source: MedTech Insight; Transparency Market Research
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*** Average (figures vary from sale to sale)
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**** Distribution contingent on CFDA approval
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…to Continue Recent Trends On track to break even in 2016 by continuing 60%+ revenue growth
Sales Revenues
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$1,600k
Quarterly
$1,400k Cumulative Annual Sales
$1,200k
$1,000k
$800k
$600k
$400k
$200k
$0k
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Annual Net Loss
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2011 2012 2013 2104 2015 2016
$0k
-$500k
-$1,000k
-$1,500k
-$2,000k
-$2,500k
-$3,000k
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A number of key USCOM 1A and BP+ revenue drivers already in train, with June 2015 a profitable month **
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- Estimate
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** June 15 figures unaudited
USCOM 1A Around the World
•• •[•][•][•] • •• • • • • • •• • • • • • • • • • • • • • • • • • • • Key Markets •[•] • 1. Nth America 2. Europe 3. AsiaPAC
Over 700 USCOM units sold worldwide
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Uscom Growth
Fluid, Sepsis
Hypertension & Vascular Health
& Heart Failure
-
US 1.3bn market[ * ]
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US 1.7bn market[ *]
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CAGR of 7.6%[ *]
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CAGR of 11.5%[ *]
USCOM 1A
BP+
Cardiac Output Monitoring Blood Pressure Monitoring
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COPD
& Asthma
-
US 400m market[ *]
-
CAGR of 6.5%[ *]
Unmet Need
Pulmonary Monitoring
?
Complementary products and technology
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- Source: MedTech Insight; Transparency Market Research
Thor Acquisition – the Next Step
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Uscom has signed an agreement to acquire 100% of Thor Laboratories *
Company Overview
2014 Financials
High fidelity digital Doppler spirometry devices
- Sales revenue of $500k
Established ISO manufacturing - 15 years
- Costs of $450k
Global reach with CE, TGA and FDA approval
- Profits of $32k
Reimbursement in multiple markets
-
Cash, inventory and receivables of $350k
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Strong R&D and grant capabilities
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Gross margins of 70%+
Adding revenue, distribution, internationally accredited manufacturing, personnel and products
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- Agreement subject to DD and Uscom capital raise
Deal Rationale and Structure
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Revenue Synergies
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Established complementary distribution channels
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Complementary product sets
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Suited to huge China/US home care markets
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Cost & Development Synergies
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Low cost, established and accredited R&D/manufacturing
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New prototypes products already in testing
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Firm links with Budapest University
Combined Business is De-Risked
- Revenue diversification
Deal Structure
Total Consideration $1 million
= Upfront $700k cash
Earnouts
$100k cash (12 months) $100k cash (24 months) $100k shares (over 3 years)*
- Improved access to R&D grants
Acquisition includes $350k of cash, inventory and receivables
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- Consists of 500,000 shares (value based on a share price of $0.20)
Uscom Growth
Fluid, Sepsis
Hypertension & Vascular Health
& Heart Failure
-
US 1.3bn market[ * ]
-
US 1.7bn market[ *]
-
CAGR of 7.6%[ *]
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CAGR of 11.5%[ *]
USCOM 1A
BP+
Cardiac Output Monitoring Blood Pressure Monitoring
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COPD
& Asthma
-
US 400m market[ *]
-
CAGR of 6.5%[ *]
Thor Pulmonary Monitoring
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?
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Complementary products and technology
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- Source: MedTech Insight; Transparency Market Research
Thor Manufacturing
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Global approvals
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Manufacturing and R&D
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Experienced engineers
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Established reputation
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USCOM and BP+ reserve
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University Budapest links
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Internationally ISO accredited medical device manufacturing
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Thor Products
Products in Market
Digital Doppler Spirometer Home use
With Diagnostics and WIFI Digital wifi spirometer
Professional System
Desktop with advanced software analytics
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Products in Development
Prototype 1
Drug delivery measure
Prototype 2
Digital wifi spirometer
Prototype 3 Neonatal Asthma diagnostic
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Uscom Post-Acquisition Manufacturing Products Distribution Sales Partners Revenue[] and R&D $1.0m 40 Thor 18 7 $2.5m 36 Uscom 3 2 Thor’s cost per head 2 products Attractive diversified Immediate 1/7 of Uscom’s to 9 products offering top line impact*
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- Estimated 2016 revenues
Acquisition and Growth
More products and increased distribution in US, Europe and Asia
| 2015 | US | Euro | Asia | Revenue |
|---|---|---|---|---|
| 1A | $0.2 | $0.8 | $1 | $2 |
| BP+ | $0 | $0 | $0 | $0 |
| Thor | $0 | $0.5 | $0 | $0 |
Revenue $2m
| 2020 | US | Euro | Asia | Revenue |
|---|---|---|---|---|
| 1A | $2 | $2 | $3 | $7 |
| BP+ | $3 | $3 | $3 | $9 |
| Thor | $1 | $1 | $2 | $4 |
Revenue $20m
$20m revenue in 2020 delivers a 5 year CAGR of 58%
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$20m Revenue by 2020
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Thor
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Projected Revenues
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$18 m
$16 m
$14 m
$12 m
$10 m
$8 m
$6 m
$4 m
$2 m
$0 m
2015 2016 2017 2018 2019
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BP+
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USCOM
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$20m revenue in 2020 delivers a 5 year CAGR of 58%
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Key Goals & Milestones
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Core focus is driving distribution to increase sales and grow revenue
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Key steps are reimbursement, regulatory approval and more distributors
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Active IR/capital markets program to address liquidity
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Also boosting resources to bed down Thor acquisition
Quarter 3 Quarter 4 Quarter 1 Quarter 2 2015 2015 2016 2016 Completion of USCOM 1A Australian BP+ Chinese Thor Integration Capital Raise IR program Reimbursement Approval Distribution Begins Completion of Thor Senior Sales & BP+ CFDA US Sales from BP+ Acquisition Marketing Hire Approval Reimbursement
Driving towards $20m revenue in 2020
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Key Business Risks & Mitigants
| Thor integration & key staff retention Ongoing Thor business management Competitiveness of market sectors Thor distraction from USCOM & BP+ Regulatory costs and timelines Distribution & revenue growth Working capital requirements to support additional sales Key Risks |
Earn outs in Thor deal structure Senior sales and marketing resource; increased marketing spend Product diversification Resources focussed on integration Key Uscom and Thor staff Senior sales and marketing resource Additional WC in capital raise Key Mitigants |
|
|---|---|---|
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July 2015 Capital Raise
Raise managed by Patersons Securities
Cornerstone private placement (PP) and share purchase plan (SPP)
Indicative Raise Overview
10m PP + 2m SPP shares (vs. 80m currently on issue) Issuance Volume[ ] 3.3m options Issue Price $0.15 per share Attaching Option 1-for-3 unlisted option Strike $0.25 and maturity 31 July 2017 Available to PP subscribers only Capital Raise Target[] $1.8m Issuance Structure $1.5m PP and $0.3m SPP Intended Use of Funds $1m Thor purchase and integration Balance: sales, marketing, regulatory, reimbursement, working capital and IR
Capital facilitates Thor acquisition & integration and Uscom’s growth plans
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- Uscom reserves the right to take additional capital, but is under no obligation to do so
Uscom
Thor Acquisition – Value at many levels
New product suite ✓ Accredited manufacturing ✓ Skilled personnel ✓ Revenue ✓ Increased distribution ✓
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Appendices
Uscom Products
Three product ranges each at commercialization phase
| Concept | Product | Pilot | Validation | Regulatory | Revenue | Global Distribution |
Profit 2016 |
|
|---|---|---|---|---|---|---|---|---|
| USCOM | ✓ |
✓ |
✓ |
✓ |
✓ |
✓ |
✓ |
±✓ |
| Uscom BP+ |
✓ |
✓ |
✓ |
✓ |
✓ |
✓ |
✓ |
±✓ |
| Thor | ✓ |
✓ |
✓ |
✓ |
✓ |
✓ |
✓ |
✓ |
Turning unrecognised IP into balance sheet value
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Regulatory Strategy
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All devices CE and TGA approved
Device FDA approval in process Next step is CFDA approval
| USCOM 1A | BP+ | Thor | |
|---|---|---|---|
| FDA | ✓ |
✓ |
P |
| CE | ✓ |
✓ |
✓ |
| CFDA | ✓ |
P | -- |
| TGA | ✓ |
✓ |
✓ |
-
✓ Approved
-
P[Preparation for submission ]
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Not yet submitted
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Reimbursement Strategy
Reimbursement consultant appointed
| USCOM 1A | Uscom BP+ | Thor | |
|---|---|---|---|
| MSAC (Aus) | Initiated | Background | Existing |
| CPT (USA) | Background | Granted | Existing |
| NHS (UK) | Review | Background | Existing |
| ROW | - | - | - |
Timelines
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USCOM 1A : Australia Aug 2015; UK Oct 15; US 2016
-
BP+ : Australia Nov 2015; UK Nov 2015
Thor devices mostly reimbursed
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USCOM Saving Lives
National ICU Study – Sepsis and septic shock mortality 6yr Australian Practice Audit ANZICS CORE Adult database
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25
20
15
BUSH protocol
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introduced
5
0
2006 2007 2008 2009 2010 2011 2012
Bathurst USCOM Australia Australian Rural
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Smith BE, Phillips RA, Madigan V, West MJ. Decreased Mortality, Morbidity and Emergency Transport in Septic Shock; A New Protocol Based on Advanced Noinvasive Haemodynamics (USCOM) and Early Antibiotics. Crit Care Med 2012; 40(12):1023. doi: 10.1097/01.ccm.0000424114.76434.7a
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USCOM Saving Lives
-
10 Million women get pre-eclampsia per year
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76,000 mothers die per year (200 per day) and 500,000 unborn babies (1300 per day)
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Early detection and treatment associated with better
outcomes
- USCOM detects pre-eclampsia at 5 weeks not 20 weeks
as current
- USCOM recommended as pregnancy screening method to detect pre-eclampsia – one USCOM in every
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obstetrician’s office?
- G.M. Tiralongo, D. Lo Presti, I. Pisani, G. Gagliardi, R.L. Scala, G.P. Novelli, B. Vasapollo, A. Andreoli, H. Valensise. Assessment of total vascular resistance and total body water in normotensive women during the first trimester of pregnancy. A key for the prevention of preeclampsia. Hypertension pregnancy 2015; 5(2):DOI: http://dx.doi.org/10.1016/j.preghy.2015.02.001
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USCOM Reducing Costs
National ICU Study 6 yr Australian Practice Audit ANZICS CORE Adult database Mean Cost per Admission 2007- 2012
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$60,000
$48,000
$50,000
$41,645
$40,000
$30,000 $26,273
$20,000
$10,000
$0
Australian Australian Rural BUSH
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Mean cost per hospitalisation for sepsis and septic shock patients between 2007 - 2012 assuming $1233 per ward day and $4427 per ICU day.
Smith BE, Phillips RA, Madigan V, West MJ. Decreased Mortality, Morbidity and Emergency Transport in Septic Shock; A New Protocol Based on Advanced Noinvasive Haemodynamics (USCOM) and Early Antibiotics. Crit Care Med 2012; 40(12):1023. doi: 10.1097/01.ccm.0000424114.76434.7a
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De-Risked Technology
Featured in 400+ peer reviewed publications and presentations
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Sepsis, Heart failure, Hypertension, Fluid management, Emergency, Pediatrics, Cardiac transplantation, Electrophysiology, Emergency transport, Anesthesia, Liver transplantation, ICU, Pre-eclampsia, Pulmonary hypertension, Nurse outreach, Organ procurement, Haemodialysis, Neonates, infants, Children etc……..
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USCOM 1A Competitive Advantage
| Method | Manufacturer | Technology | Rel+Rep | Non- invasive |
Simple | Cost | Portable | SV beat to beat |
|---|---|---|---|---|---|---|---|---|
| USCOM 1A | Uscom | Doppler | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| BioZ | Samsung | BioImpedance | ✗ | ✓ | ✓ | ✗ | ✓ | ✗ |
| NiCOM | Cheetah | BioReactance | ✗ | ✓ | ✓ | ✗ | ✓ | ✗ |
| Nexfin | Bmeye | APP | ✗ | ✓ | ✓ | ✓ | ✓ | ✗ |
| CardioQ | Deltex | Doppler | ✓ | ✗ | ✓ | ✗ | ✓ | ✗ |
| LiDCO | LiDCO | LiCl dilutio +APP | ✓ | ✗ | ✗ | ✗ | ✗ | ✗ |
| LiDCOrapid | LiDCO | APP | ✗ | ✗ | ✓ | ✗ | ✗ | ✗ |
| PiCCO (mod Tx + PP) |
Pulsion | APP | ✓ | ✗ | ✗ | ✗ | ✗ | ✗ |
| FloTrac | Edwards | APP | ✗ | ✗ | ✗ | ✗ | ✗ | ✗ |
| PAC (Tx) | Many | Thermodilution | ✗ | ✗ | ✗ | ✗ | ✗ | ✗ |
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Testimonials
“This machine is saving lives, there are no two ways about it.”
Professor Brendan Smith, Anesthetist, Intensivist and Emergency Physician, N.S.W. Dept of Health, Australia
“USCOM has changed the way I look at the cardiovascular status of my patients.
It’s part of the initial shock evaluation and monitored regularly thereafter…. USCOM has now been established as the standard of care.”
Dr Akash Deep, Director of Paediatric ICU, King's College Hospital, London
“The USCOM device is a simple method of accurately and noninvasively measuring central circulation, a goal of cardiology for many years. The device has the potential to change the way we approach management of sepsis, heart failure and hypertension.”
Professor Malcolm West, Cardiologist, Mayne Professor of Medicine at The University of Queensland School of Medicine, Brisbane, Australia and Uscom Medical Advisory Board Member.
“I have used USCOM for over 5 years now on our very sick children, and use it to guide management. We are now beginning multi-centre, global research which will define the way USCOM is used in Paediatric Departments across the world.”
Dr Joe Brierley, Consultant Intensivist, Great Ormond Street Hospital for Sick Children, London, UK.
“The USCOM device is really good; I use it in all my aneasthetics. I think there should be one on every ICU bed and on every anaesthetic patient.”
Dr Steve Woodford, Consultant Anaesthetist, circulatory researcher at Australian School of Advanced Medicine, and Uscom Investor,
“To parents and doctors this machine, USCOM, is priceless. This machine is thought to have saved baby Abbie’s life.
BBC Documentary “New machine helps save babies life”, 2010, Nottingham Children’s Hospital
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BP+ Competitive Advantage
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| Uscom BP+ | TensioMed | BPLab | IEM | Centron | AtCor |
|---|---|---|---|---|---|
| Australia | Hungary | Russia | Germany | UK | Australia |
| USD 3,950 | USD 6,000 | USD 7,000 | USD 7,000 | USD 6,300 | USD 14,000 |
| 1 min | 2 min | 2 min | 2 min | 1 min | 1 min |
| Stand-alone | ABP, needs computer |
ABP, needs computer |
ABP, needs computer |
Stand-alone | Needs computer |
| CE, FDA, TGA | CE | CE | CE, FDA | CE | CE, FDA |
| Aortic + brachial waveform |
Central systolic BP | Rough waveform | Rough waveform | Rough waveform | Rough waveform |
| Physical model | Statistical regression | Transfer function | Transfer function | Transfer function | Transfer function |
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Why ?
Independent research from Cambridge University, Weill Cornell, University of California, Wales Heart Institute – BP+ = Four stars
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BP+ is on the international space station
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McEniery CM, Cockcroft JR, Roman MJ, Franklin SS, Wilkinson AB. Central blood pressure: current evidence and clinical importance. Euro Heart J 2014;doi10.1093/ eurojeartj/eht565
BP+ US Reimbursement
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US Category 1 CPT Code recommended by AMA CPT panel *
CPT Category 1 Code (9300X1)
Non-invasive calculation and analysis of central arterial pressure waveforms with interpretation and report
Effective January 2016
- BP+ has US FDA clearance
Key revenue driver for BP+ in the most important
market globally
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Broad Patent Portfolio
Core technology patent protected, with patents running to 024 and beyond
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USCOM 1A
BP+
-
22 granted patents
-
34 granted patents
-
5 pending applications
4 registered trademarks
2 registered trademarks
IP protected in key markets
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Growth in Distribution
Distribution Agreements
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25
20
15
12
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5
0
2013 2014 2015
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Further distribution through Thor and greater focus through recent hires
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- FY to date
George Ferenczi
-
Founder of THOR
-
15 years building Thor and Thor products
-
Innovative and global leading bio-engineer
-
Specialist in Computer Engineering
-
10 years global executive management
-
Experienced in channel management and distribution
-
Will join Uscom as Manager of Product Development and manager of new operations
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George to split his time between Sydney and Budapest
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Spirometry
Lung disease increasing worldwide with reduced air quality – Asthma, COPD, Industrial lung disease
Spirometry
- Measures the volume, and rate of inspired and expired air to identify disease (Asthma and COPD), investigate SOB (short of breath), monitor disease and therapy, industrial disease detection, pre-op assessment, lung function recovery (smoking etc.)
Digital Doppler Spirometry
-
Spirometry using Digital Doppler
-
Identical technique to Uscom 1A
Market
-
Asthma – 250-300m sufferers worldwide and 250,000 deaths and increasing
-
COPD – 4th leading cause of US death, one US death per 4 minutes, and 24m sufferers
-
Estimated - $400m USD with CAGR 6.5%
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Post-Acquisition Revenue Drivers
-
US BP+ Re-imbursement - CPT category 1 code (9300X1) effective January 2016
-
Thor FDA (pending)
-
USCOM 1A and BP+ sales pipeline growing (Pioneer + Europe)
-
Increased distribution (Uscom + Thor) – 30 to 60 (+100%) increases revenue for all products
-
New clinical science
-
9 products with consumables – attractive to higher volume distributors
Great revenue opportunities
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