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Upstream Bio, Inc. — Director's Dealing 2026
Jan 6, 2026
32187_dirs_2026-01-06_1590243d-1cb5-4891-b3a5-cfe94921a31a.zip
Director's Dealing
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SEC Form 4 — Statement of Changes in Beneficial Ownership
Issuer: Upstream Bio, Inc. (UPB)
CIK: 0002022626
Period of Report: 2026-01-02
Reporting Person: Houghton Adam (N/A)
Non-Derivative Transactions
| Date | Security | Code | Shares | Price | A/D | Holdings After | Ownership |
|---|---|---|---|---|---|---|---|
| 2026-01-02 | Common Stock | A | 25000 | — | Acquired | 25000 | Direct |
Derivative Transactions
| Date | Security | Exercise Price | Code | Shares | A/D | Expiration | Underlying | Ownership |
|---|---|---|---|---|---|---|---|---|
| 2026-01-02 | Stock Option (Right to Buy) | $27.07 | A | 75000 | Acquired | 2036-01-01 | Common Stock (75000) | Direct |
Footnotes
F1: Represents restricted stock units ("RSUs") granted pursuant to the Issuer's 2024 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting. The RSUs shall vest in sixteen equal quarterly installments following January 1, 2026, subject to the Reporting Person's continued service on each such vesting date.
F2: The shares underlying this option shall vest in forty-eight equal monthly installments following January 1, 2026, subject to the Reporting Person's continued service on each such vesting date.