Tyra Biosciences, Inc. — Director's Dealing 2021

Sep 17, 2021

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Tyra Biosciences, Inc. (TYRA)
CIK: 0001863127
Period of Report: 2021-09-17

Reporting Person: RA CAPITAL MANAGEMENT, L.P. (Director, 10% Owner)
Reporting Person: RA Capital Healthcare Fund LP (Director, 10% Owner)
Reporting Person: RA Capital Nexus Fund, L.P. (Director, 10% Owner)
Reporting Person: Kolchinsky Peter (Director, 10% Owner)
Reporting Person: Shah Rajeev M. (Director, 10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2021-09-17	Common Stock	C	4047120	—	Acquired	4047120	Indirect
2021-09-17	Common Stock	P	1250000	$16	Acquired	5297120	Indirect
2021-09-17	Common Stock	C	1496613	—	Acquired	1496613	Indirect
2021-09-17	Common Stock	C	442721	—	Acquired	442721	Indirect

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2021-09-17	Series A Preferred Stock	$	C	1011370	Disposed		Common Stock (2626932)	Indirect
2021-09-17	Series A Preferred Stock	$	C	393940	Disposed		Common Stock (1023219)	Indirect
2021-09-17	Series A Preferred Stock	$	C	170448	Disposed		Common Stock (442721)	Indirect
2021-09-17	Series B Preferred Stock	$	C	546773	Disposed		Common Stock (1420188)	Indirect
2021-09-17	Series B Preferred Stock	$	C	182257	Disposed		Common Stock (473394)	Indirect

Footnotes

F1: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F2: These securities are held directly by RA Capital Healthcare Fund, L.P. (the "Fund").

F3: These securities are held directly by RA Capital Nexus Fund, L.P. (the "Nexus Fund").

F4: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund, the Nexus Fund, and a separately managed account (the "Account"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

F5: These securities are held directly by the Account.